Basic Information
ID: ALA1613974
Type: Functional
Description: PUBCHEM_BIOASSAY: Secondary assay for Activators of Human Pyruvate Kinase M2 isoform - Cell Titer Glo cytotoxicity assay. Measurement of cytotoxicity by measuring the total ATP content of Hela cells after 24 hrs of exposure to compound (Class of assay: confirmatory) [Related pubchem assays: 1540 (Secondary assay for Activators of Human Pyruvate Kinase M2 isoform.), 1751 (Confirmation Concentration-Response Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase.), 954 (qHTS Assay for Activators of Human Muscle Pyruvate Kinase.), 1631 (qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase.)]
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: HeLa(ALA399)
Document: ALA1201862
PubChem Source: AID:1898
Activity Charts
Bioactivity
Activity Types for Assay ALA1613974
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.95 | 1.81 | 1.81 |
| 460.48 | 1.43 | 1.43 |
| 454.53 | 1.16 | 1.16 |
| 474.51 | 1.82 | 1.82 |
| 446.45 | 1.39 | 1.39 |
| 459.49 | 2.36 | 2.36 |
| 424.43 | 1.88 | 1.88 |
| 460.48 | 1.48 | 1.48 |
| 474.51 | 1.82 | 1.82 |
| 341.41 | 3.70 | 3.70 |
| 355.44 | 4.26 | 4.26 |
| 313.36 | 3.14 | 3.14 |
| 445.52 | 5.43 | 5.43 |
| 329.43 | 4.19 | 4.19 |
| 403.49 | 2.85 | 2.85 |
| 380.43 | 3.14 | 3.14 |
| 381.46 | 4.14 | 4.14 |
| 421.48 | 2.20 | 2.20 |
| 360.45 | 4.15 | 4.15 |
| 361.85 | 3.68 | 3.68 |
| 352.42 | 3.62 | 3.62 |
| 450.54 | 3.62 | 3.62 |
| 330.41 | 2.99 | 2.99 |
| 436.99 | 4.78 | 4.78 |
| 401.47 | 5.38 | 5.38 |