ID: ALA1613988
Type: Functional
Description: PUBCHEM_BIOASSAY: Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Confirmation in an HTRF (commercial TR-FRET) Assay using His-tagged menin and biotin-labeled MLL peptide. (Class of assay: confirmatory) [Related pubchem assays: 1768, 2076, 1766 ]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1613988
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
302.19 | 1.31 | 1.31 |
502.80 | 0.42 | 0.42 |
276.34 | 4.49 | 4.49 |
272.21 | 1.28 | 1.28 |
394.32 | 4.13 | 4.13 |
240.21 | 1.87 | 1.87 |
393.40 | 4.61 | 4.61 |
321.76 | 0.83 | 0.83 |
399.87 | 4.07 | 4.07 |
580.55 | 6.04 | 6.04 |
310.40 | 1.73 | 1.73 |
446.53 | 4.74 | 4.74 |
746.74 | 6.24 | 6.24 |
566.52 | 5.74 | 5.74 |
407.85 | 5.00 | 5.00 |
477.03 | 3.64 | 3.64 |
457.53 | 2.34 | 2.34 |
563.91 | 4.32 | 4.32 |
561.72 | 5.35 | 5.35 |
367.88 | 5.37 | 5.37 |
422.98 | 3.26 | 3.26 |
720.67 | 6.20 | 6.20 |
468.35 | 4.29 | 4.29 |
317.39 | 0.85 | 0.85 |
329.22 | 1.69 | 1.69 |
376.33 | ||
342.42 | 2.81 | 2.81 |
438.46 | 3.34 | 3.34 |
427.55 | 3.71 | 3.71 |
359.18 | 4.06 | 4.06 |
497.65 | 4.32 | 4.32 |
351.39 | 4.34 | 4.34 |
494.35 | 5.27 | 5.27 |
365.21 | 4.12 | 4.12 |
374.27 | 1.20 | 1.20 |
356.50 | 4.27 | 4.27 |
338.36 | 1.98 | 1.98 |
431.54 | 5.32 | 5.32 |
339.80 | 3.93 | 3.93 |
474.59 | 4.90 | 4.90 |
387.58 | 3.57 | 3.57 |
395.49 | 6.01 | 6.01 |
283.29 | 1.87 | 1.87 |
396.42 | 3.37 | 3.37 |
436.49 | 4.74 | 4.74 |
431.29 | 4.28 | 4.28 |
442.56 | 3.95 | 3.95 |
228.25 | 3.03 | 3.03 |
527.57 | 0.47 | 0.47 |
447.93 | 5.00 | 5.00 |
251.28 | 4.06 | 4.06 |
405.45 | 6.14 | 6.14 |
480.59 | 5.13 | 5.13 |
262.74 | 3.03 | 3.03 |
479.54 | 5.35 | 5.35 |
352.42 | 3.25 | 3.25 |
379.55 | 3.88 | 3.88 |
419.48 | 3.53 | 3.53 |
450.54 | 6.17 | 6.17 |
388.25 | 3.92 | 3.92 |
439.59 | 5.52 | 5.52 |
396.97 | 2.99 | 2.99 |
578.38 | 4.18 | 4.18 |
465.77 | 5.94 | 5.94 |
475.60 | 5.12 | 5.12 |
352.51 | 4.38 | 4.38 |
349.21 | 3.69 | 3.69 |
394.52 | 4.14 | 4.14 |
549.48 | 6.44 | 6.44 |
494.62 | 5.44 | 5.44 |
363.24 | 4.08 | 4.08 |
317.22 | 2.49 | 2.49 |
559.49 | 3.68 | 3.68 |
358.49 | 2.72 | 2.72 |
367.88 | 1.10 | 1.10 |
535.62 | 4.74 | 4.74 |
456.48 | 5.30 | 5.30 |
279.30 | 3.04 | 3.04 |
268.74 | 2.36 | 2.36 |
297.31 | 1.96 | 1.96 |
393.46 | 4.89 | 4.89 |
385.42 | 4.59 | 4.59 |
527.53 | 4.37 | 4.37 |
381.87 | 4.00 | 4.00 |
349.14 | 3.66 | 3.66 |
348.48 | 4.77 | 4.77 |
379.89 | 2.56 | 2.56 |
442.39 | 2.87 | 2.87 |
443.53 | 3.71 | 3.71 |
457.35 | 2.69 | 2.69 |
353.38 | 2.89 | 2.89 |
321.42 | 3.78 | 3.78 |
291.35 | 4.00 | 4.00 |
542.61 | 2.79 | 2.79 |
402.42 | 2.36 | 2.36 |