Basic Information
ID: ALA1613991
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Measurement of IP-One Response. (Class of assay: confirmatory)
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1613991
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 280.42 | 3.88 | 3.88 |
| 303.29 | 1.77 | 1.77 |
| 252.27 | 1.77 | 1.77 |
| 314.86 | 4.53 | 4.53 |
| 180.16 | 1.31 | 1.31 |
| 407.51 | 4.95 | 4.95 |
| 166.20 | 2.29 | 2.29 |
| 176.22 | 1.37 | 1.37 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 219.33 | 2.98 | 2.98 |
| 393.47 | 4.51 | 4.51 |
| 315.76 | 4.04 | 4.04 |
| 385.51 | 2.09 | 2.09 |
| 302.24 | 1.99 | 1.99 |
| 184.96 | -0.09 | -0.09 |
| 375.87 | 4.43 | 4.43 |
| 393.49 | 2.89 | 2.89 |
| 272.18 | 3.33 | 3.33 |
| 444.49 | -0.14 | -0.14 |
| 336.33 | -0.13 | -0.13 |
| 395.48 | 3.22 | 3.22 |
| 339.48 | 3.36 | 3.36 |
| 304.25 | 1.19 | 1.19 |
| 196.68 | 1.75 | 1.75 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 210.28 | 2.38 | 2.38 |
| 234.34 | 2.58 | 2.58 |
| 351.41 | 1.56 | 1.56 |
| 473.59 | 6.08 | 6.08 |
| 410.49 | 3.59 | 3.59 |
| 198.27 | 2.70 | 2.70 |
| 105.09 | -1.61 | -1.61 |
| 285.39 | 2.66 | 2.66 |
| 477.58 | 5.48 | 5.48 |
| 304.22 | 3.38 | 3.38 |
| 287.41 | 4.70 | 4.70 |
| 174.26 | 0.23 | 0.23 |
| 332.34 | 3.43 | 3.43 |
| 324.42 | 3.17 | 3.17 |
| 348.38 | 3.72 | 3.72 |
| 331.35 | 1.58 | 1.58 |
| 314.47 | 4.72 | 4.72 |
| 385.51 | 2.53 | 2.53 |
| 426.56 | 4.13 | 4.13 |
| 309.43 | 4.01 | 4.01 |
| 216.28 | 1.94 | 1.94 |
| 197.24 | 1.58 | 1.58 |
| 110.11 | 1.10 | 1.10 |
| 344.85 | 5.38 | 5.38 |
| 369.34 | 4.40 | 4.40 |
| 431.39 | 5.51 | 5.51 |
| 223.30 | 1.94 | 1.94 |
| 409.42 | 4.79 | 4.79 |
| 242.27 | 2.75 | 2.75 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 236.31 | 1.77 | 1.77 |
| 352.43 | 5.26 | 5.26 |
| 277.41 | 3.29 | 3.29 |
| 486.53 | 3.26 | 3.26 |
| 360.35 | 4.85 | 4.85 |
| 314.34 | 3.03 | 3.03 |
| 260.38 | 2.85 | 2.85 |
| 471.69 | 6.45 | 6.45 |
| 335.45 | 5.43 | 5.43 |
| 163.20 | -0.49 | -0.49 |
| 213.28 | 1.64 | 1.64 |
| 393.46 | 3.28 | 3.28 |
| 212.30 | 2.25 | 2.25 |
| 241.68 | 0.82 | 0.82 |
| 339.39 | 3.86 | 3.86 |
| 283.33 | 2.56 | 2.56 |
| 403.53 | 4.06 | 4.06 |
| 246.31 | 4.49 | 4.49 |
| 145.25 | -0.34 | -0.34 |
| 450.57 | 5.32 | 5.32 |
| 250.30 | 0.72 | 0.72 |
| 520.63 | 5.58 | 5.58 |
| 277.41 | 4.17 | 4.17 |
| 230.10 | 2.36 | 2.36 |
| 255.36 | 3.35 | 3.35 |
| 277.41 | 4.21 | 4.21 |
| 263.38 | 4.30 | 4.30 |
| 275.40 | 4.55 | 4.55 |
| 265.37 | 3.51 | 3.51 |
| 320.43 | 5.17 | 5.17 |
| 382.46 | 2.86 | 2.86 |
| 264.37 | 2.62 | 2.62 |
| 387.48 | 0.72 | 0.72 |
| 417.55 | 4.18 | 4.18 |
| 353.51 | 4.66 | 4.66 |
| 247.38 | 3.37 | 3.37 |
| 414.59 | 5.04 | 5.04 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 256.10 | 2.01 | 2.01 |
| 352.74 | 5.22 | 5.22 |
| 347.86 | 4.47 | 4.47 |
| 422.57 | 3.83 | 3.83 |
| 354.45 | 2.65 | 2.65 |
| 582.92 | 7.22 | 7.22 |
| 260.38 | 2.85 | 2.85 |
| 395.47 | 4.23 | 4.23 |
| 608.69 | 4.17 | 4.17 |
| 266.73 | 2.51 | 2.51 |
| 139.09 | -0.49 | -0.49 |
| 312.80 | 2.57 | 2.57 |
| 311.38 | 3.34 | 3.34 |
| 374.28 | 4.04 | 4.04 |
| 255.32 | 2.38 | 2.38 |
| 342.44 | 3.48 | 3.48 |
| 276.21 | 3.21 | 3.21 |
| 454.61 | 5.09 | 5.09 |
| 345.40 | 2.51 | 2.51 |
| 340.88 | 3.29 | 3.29 |
| 340.49 | 4.83 | 4.83 |
| 227.31 | 1.99 | 1.99 |
| 477.05 | 5.09 | 5.09 |
| 295.73 | -0.06 | -0.06 |
| 292.34 | 3.17 | 3.17 |
| 338.21 | 4.10 | 4.10 |
| 434.53 | 4.60 | 4.60 |
| 220.34 | 3.21 | 3.21 |
| 279.38 | 3.96 | 3.96 |
| 475.58 | 5.31 | 5.31 |
| 368.52 | 5.11 | 5.11 |
| 195.29 | 0.32 | 0.32 |
| 334.42 | 2.38 | 2.38 |
| 252.21 | -1.09 | -1.09 |
| 264.33 | 3.25 | 3.25 |
| 495.64 | 5.27 | 5.27 |
| 308.37 | 0.94 | 0.94 |
| 123.54 | -0.36 | -0.36 |
| 336.44 | 2.75 | 2.75 |
| 271.40 | 3.38 | 3.38 |
| 327.18 | 4.09 | 4.09 |
| 258.06 | 2.95 | 2.95 |
| 75.07 | -1.47 | -1.47 |
| 302.20 | 3.17 | 3.17 |
| 247.38 | 3.37 | 3.37 |
| 271.40 | 3.33 | 3.33 |
| 253.32 | 0.98 | 0.98 |
| 294.31 | 2.32 | 2.32 |
| 297.27 | 2.30 | 2.30 |
| 308.34 | 2.36 | 2.36 |
| 322.36 | 2.75 | 2.75 |
| 280.28 | 2.64 | 2.64 |
| 284.36 | 2.95 | 2.95 |
| 340.85 | 4.30 | 4.30 |
| 418.28 | 3.49 | 3.49 |
| 270.21 | 3.25 | 3.25 |
| 291.44 | 4.56 | 4.56 |
| 344.91 | 4.34 | 4.34 |
| 312.41 | 2.53 | 2.53 |
| 193.25 | 2.79 | 2.79 |
| 290.41 | 3.79 | 3.79 |
| 448.44 | 1.65 | 1.65 |
| 307.40 | 2.77 | 2.77 |
| 382.89 | 3.36 | 3.36 |
| 224.22 | -0.71 | -0.71 |
| 249.31 | 1.94 | 1.94 |
| 382.89 | 4.89 | 4.89 |
| 355.31 | 4.01 | 4.01 |
| 326.44 | 3.52 | 3.52 |
| 244.38 | 3.15 | 3.15 |
| 520.95 | 5.01 | 5.01 |
| 317.43 | 2.76 | 2.76 |
| 246.31 | 1.38 | 1.38 |
| 361.46 | 3.23 | 3.23 |
| 293.41 | 3.77 | 3.77 |
| 220.25 | 1.29 | 1.29 |
| 202.17 | 1.23 | 1.23 |
| 216.20 | 1.54 | 1.54 |
| 282.39 | 4.42 | 4.42 |
| 255.16 | 2.16 | 2.16 |
| 113.16 | 1.14 | 1.14 |
| 328.43 | 1.17 | 1.17 |
| 381.55 | 5.16 | 5.16 |
| 268.22 | 2.05 | 2.05 |
| 197.13 | -0.64 | -0.64 |
| 376.39 | 0.53 | 0.53 |
| 303.41 | 4.89 | 4.89 |
| 401.51 | 1.03 | 1.03 |
| 506.56 | 2.86 | 2.86 |
| 211.70 | 1.66 | 1.66 |
| 277.37 | 1.72 | 1.72 |
| 166.24 | 1.98 | 1.98 |
| 373.88 | 2.90 | 2.90 |
| 286.36 | 3.59 | 3.59 |
| 293.37 | 3.41 | 3.41 |
| 313.79 | 3.43 | 3.43 |
| 380.50 | 3.12 | 3.12 |
| 257.38 | 3.10 | 3.10 |
| 309.49 | 4.40 | 4.40 |
| 238.29 | 3.12 | 3.12 |
| 172.24 | -1.27 | -1.27 |
| 160.24 | 0.45 | 0.45 |
| 176.31 | 1.17 | 1.17 |
| 248.27 | 3.81 | 3.81 |
| 282.44 | 2.02 | 2.02 |
| 331.76 | 3.21 | 3.21 |
| 137.12 | 0.24 | 0.24 |
| 359.73 | 2.43 | 2.43 |
| 335.67 | 3.04 | 3.04 |
| 456.68 | 6.17 | 6.17 |
| 195.69 | 2.37 | 2.37 |
| 304.35 | 3.84 | 3.84 |
| 258.49 | 3.52 | 3.52 |
| 152.15 | 0.00 | 0.00 |
| 173.17 | -0.48 | -0.48 |
| 386.45 | 5.28 | 5.28 |
| 135.17 | 0.55 | 0.55 |
| 604.70 | 3.54 | 3.54 |
| 1162.89 | ||
| 191.30 | 1.58 | 1.58 |
| 195.22 | 0.78 | 0.78 |
| 187.16 | 0.85 | 0.85 |
| 266.34 | 0.45 | 0.45 |
| 495.58 | 4.94 | 4.94 |
| 181.24 | 0.68 | 0.68 |
| 317.22 | 2.45 | 2.45 |
| 168.15 | 0.72 | 0.72 |
| 289.34 | 2.44 | 2.44 |
| 531.44 | 4.21 | 4.21 |
| 243.29 | 2.36 | 2.36 |
| 336.33 | -1.72 | -1.72 |
| 91.07 | -1.04 | -1.04 |
| 279.38 | 2.98 | 2.98 |
| 267.36 | 3.13 | 3.13 |
| 138.17 | 0.36 | 0.36 |
| 324.44 | 3.60 | 3.60 |
| 317.23 | 3.84 | 3.84 |
| 356.18 | 5.18 | 5.18 |
| 176.18 | -1.80 | -1.80 |
| 510.83 | 5.45 | 5.45 |
| 592.69 | 2.88 | 2.88 |
| 332.48 | 3.77 | 3.77 |
| 319.76 | 0.54 | 0.54 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 318.39 | 1.06 | 1.06 |
| 307.10 | -1.06 | -1.06 |
| 327.12 | 3.86 | 3.86 |
| 240.35 | 3.17 | 3.17 |
| 211.22 | 1.62 | 1.62 |
| 210.28 | 0.07 | 0.07 |
| 178.14 | 1.20 | 1.20 |
| 310.40 | 1.73 | 1.73 |
| 312.82 | 2.51 | 2.51 |
| 446.37 | 3.58 | 3.58 |
| 278.40 | 3.92 | 3.92 |
| 346.47 | 2.81 | 2.81 |
| 360.45 | 1.99 | 1.99 |
| 346.34 | 2.18 | 2.18 |
| 239.75 | 3.30 | 3.30 |
| 319.88 | 4.81 | 4.81 |
| 324.40 | 3.81 | 3.81 |
| 384.26 | 3.96 | 3.96 |
| 414.35 | 3.44 | 3.44 |
| 284.43 | 4.24 | 4.24 |
| 370.48 | 2.53 | 2.53 |
| 248.31 | 1.96 | 1.96 |
| 292.45 | 2.80 | 2.80 |
| 395.54 | 4.55 | 4.55 |
| 241.25 | 1.91 | 1.91 |
| 277.27 | 1.15 | 1.15 |
| 218.21 | 1.57 | 1.57 |
| 428.49 | 0.83 | 0.83 |
| 324.40 | 2.21 | 2.21 |
| 274.25 | 1.77 | 1.77 |
| 317.39 | 2.28 | 2.28 |
| 343.90 | 5.10 | 5.10 |
| 332.85 | 1.58 | 1.58 |
| 465.44 | 4.40 | 4.40 |
| 402.49 | 2.56 | 2.56 |
| 311.34 | 3.21 | 3.21 |
| 242.03 | 2.23 | 2.23 |
| 365.83 | 3.33 | 3.33 |
| 342.70 | 5.18 | 5.18 |
| 381.99 | 3.57 | 3.57 |
| 352.50 | 2.67 | 2.67 |
| 316.47 | 4.18 | 4.18 |
| 496.68 | 3.80 | 3.80 |
| 260.34 | 1.80 | 1.80 |
| 371.46 | 2.64 | 2.64 |
| 309.45 | 4.20 | 4.20 |
| 401.50 | 4.22 | 4.22 |
| 452.56 | 3.91 | 3.91 |
| 414.37 | 3.05 | 3.05 |
| 402.44 | 1.90 | 1.90 |
| 309.33 | 4.44 | 4.44 |
| 328.36 | 4.43 | 4.43 |
| 339.48 | 3.97 | 3.97 |
| 263.40 | 3.12 | 3.12 |
| 368.50 | 4.73 | 4.73 |
| 648.85 | 6.38 | 6.38 |
| 428.68 | 6.34 | 6.34 |
| 445.90 | 3.77 | 3.77 |
| 352.87 | 5.43 | 5.43 |
| 322.45 | 4.00 | 4.00 |
| 522.62 | 4.60 | 4.60 |
| 206.33 | 2.79 | 2.79 |
| 268.36 | 2.28 | 2.28 |
| 272.35 | 2.81 | 2.81 |
| 224.69 | 1.07 | 1.07 |
| 349.40 | 3.65 | 3.65 |
| 525.60 | 3.40 | 3.40 |
| 290.45 | 4.75 | 4.75 |
| 401.84 | 1.07 | 1.07 |
| 334.37 | 4.94 | 4.94 |
| 373.39 | 1.95 | 1.95 |
| 437.19 | 3.21 | 3.21 |
| 512.79 | 7.73 | 7.73 |
| 523.74 | 6.49 | 6.49 |
| 434.43 | 0.22 | 0.22 |
| 452.67 | 4.40 | 4.40 |
| 340.47 | 2.93 | 2.93 |
| 289.16 | 3.59 | 3.59 |
| 220.32 | 2.32 | 2.32 |
| 330.41 | 2.22 | 2.22 |
| 404.50 | 5.39 | 5.39 |
| 299.41 | 3.43 | 3.43 |
| 438.58 | 5.32 | 5.32 |
| 287.36 | 2.35 | 2.35 |
| 341.45 | 3.24 | 3.24 |
| 303.83 | 4.19 | 4.19 |
| 303.36 | 0.92 | 0.92 |
| 211.22 | 0.14 | 0.14 |
| 359.47 | 3.44 | 3.44 |
| 242.24 | 0.09 | 0.09 |
| 264.37 | 3.08 | 3.08 |
| 287.41 | 2.93 | 2.93 |
| 366.46 | 4.15 | 4.15 |
| 389.89 | 1.23 | 1.23 |
| 276.61 | 3.51 | 3.51 |
| 344.41 | 1.82 | 1.82 |
| 246.22 | 1.93 | 1.93 |
| 269.39 | 3.66 | 3.66 |
| 269.34 | 2.72 | 2.72 |
| 199.64 | 1.29 | 1.29 |
| 330.47 | 3.84 | 3.84 |
| 319.27 | 0.09 | 0.09 |
| 199.17 | -2.05 | -2.05 |
| 301.47 | 4.33 | 4.33 |
| 360.01 | 3.51 | 3.51 |
| 385.82 | 3.06 | 3.06 |
| 370.59 | 5.89 | 5.89 |
| 382.39 | 2.73 | 2.73 |
| 699.61 | 2.88 | 2.88 |
| 449.64 | 4.85 | 4.85 |
| 367.81 | 0.62 | 0.62 |
| 357.88 | 4.06 | 4.06 |
| 353.47 | 1.94 | 1.94 |
| 314.21 | 3.78 | 3.78 |
| 840.12 | 3.85 | 3.85 |
| 329.21 | -0.82 | -0.82 |
| 301.39 | 2.96 | 2.96 |
| 204.30 | 2.15 | 2.15 |
| 493.53 | -0.73 | -0.73 |
| 230.31 | 2.68 | 2.68 |
| 337.46 | 4.24 | 4.24 |
| 298.35 | 1.53 | 1.53 |
| 511.60 | 3.84 | 3.84 |
| 444.44 | -0.35 | -0.35 |
| 213.67 | 4.04 | 4.04 |
| 335.36 | -0.21 | -0.21 |
| 268.23 | 0.97 | 0.97 |
| 289.37 | 1.93 | 1.93 |
| 339.44 | 3.25 | 3.25 |
| 281.27 | -1.52 | -1.52 |
| 808.98 | 1.97 | 1.97 |
| 357.49 | 3.34 | 3.34 |
| 523.63 | 5.53 | 5.53 |
| 481.48 | 3.98 | 3.98 |
| 231.34 | 2.91 | 2.91 |
| 339.48 | 4.02 | 4.02 |
| 414.53 | 3.37 | 3.37 |
| 394.49 | 4.04 | 4.04 |
| 234.61 | 2.01 | 2.01 |
| 319.25 | 3.93 | 3.93 |
| 750.71 | 3.19 | 3.19 |
| 271.36 | 3.42 | 3.42 |
| 586.68 | -1.44 | -1.44 |
| 405.50 | 3.58 | 3.58 |
| 261.39 | 2.71 | 2.71 |
| 464.86 | 0.26 | 0.26 |
| 341.88 | 5.07 | 5.07 |
| 428.44 | 2.54 | 2.54 |
| 407.46 | 3.08 | 3.08 |
| 296.43 | 4.33 | 4.33 |
| 304.41 | 2.08 | 2.08 |
| 299.39 | 3.09 | 3.09 |
| 521.51 | 4.56 | 4.56 |
| 321.16 | 2.20 | 2.20 |
| 522.71 | 5.20 | 5.20 |
| 294.44 | 4.12 | 4.12 |
| 406.61 | 5.33 | 5.33 |
| 266.47 | 3.57 | 3.57 |
| 399.97 | 5.97 | 5.97 |
| 255.36 | 3.72 | 3.72 |
| 403.54 | 4.42 | 4.42 |
| 302.35 | -0.10 | -0.10 |
| 520.72 | 4.21 | 4.21 |
| 588.56 | 1.69 | 1.69 |
| 386.41 | -0.33 | -0.33 |
| 610.85 | 5.21 | 5.21 |
| 661.80 | 3.82 | 3.82 |
| 275.35 | 1.89 | 1.89 |
| 299.50 | 3.92 | 3.92 |
| 268.32 | 2.72 | 2.72 |
| 284.36 | 2.21 | 2.21 |
| 370.42 | 2.45 | 2.45 |
| 315.87 | 5.19 | 5.19 |
| 339.44 | 1.92 | 1.92 |
| 305.37 | -0.45 | -0.45 |
| 416.58 | 4.85 | 4.85 |
| 554.54 | -0.90 | -0.90 |
| 139.15 | 0.28 | 0.28 |
| 379.44 | 3.89 | 3.89 |
| 338.23 | 4.02 | 4.02 |
| 707.85 | 2.72 | 2.72 |
| 252.23 | -1.56 | -1.56 |
| 327.38 | 1.30 | 1.30 |
| 141.17 | 0.45 | 0.45 |
| 499.53 | -0.16 | -0.16 |
| 376.58 | 5.66 | 5.66 |
| 388.46 | 2.92 | 2.92 |
| 361.53 | 4.84 | 4.84 |
| 380.40 | 1.06 | 1.06 |
| 259.22 | -2.70 | -2.70 |
| 418.53 | 4.34 | 4.34 |
| 679.80 | 2.08 | 2.08 |
| 366.41 | 2.08 | 2.08 |
| 497.50 | 1.02 | 1.02 |
| 572.88 | 6.11 | 6.11 |
| 550.76 | 5.98 | 5.98 |
| 394.42 | 3.70 | 3.70 |
| 200.28 | 2.11 | 2.11 |
| 436.43 | 3.31 | 3.31 |
| 283.19 | 2.91 | 2.91 |
| 133.15 | -2.33 | -2.33 |
| 385.90 | 3.93 | 3.93 |
| 384.52 | 3.49 | 3.49 |
| 414.55 | 1.86 | 1.86 |
| 310.46 | 5.07 | 5.07 |
| 337.46 | 4.22 | 4.22 |
| 287.75 | 4.00 | 4.00 |
| 410.61 | 4.27 | 4.27 |
| 294.27 | -2.23 | -2.23 |
| 228.34 | 3.15 | 3.15 |
| 274.80 | 3.82 | 3.82 |
| 293.35 | 0.26 | 0.26 |
| 179.18 | 0.13 | 0.13 |
| 398.42 | 2.91 | 2.91 |
| 360.47 | 2.23 | 2.23 |
| 332.46 | 3.06 | 3.06 |
| 308.34 | 2.37 | 2.37 |
| 334.50 | 3.57 | 3.57 |
| 448.55 | 0.94 | 0.94 |
| 652.26 | 10.29 | 10.29 |
| 127.14 | -0.19 | -0.19 |
| 479.53 | 3.68 | 3.68 |
| 349.57 | ||
| 303.19 | 3.22 | 3.22 |
| 244.25 | 2.68 | 2.68 |
| 361.53 | 4.05 | 4.05 |
| 227.74 | 2.76 | 2.76 |
| 273.38 | 2.77 | 2.77 |
| 263.34 | 3.62 | 3.62 |
| 547.59 | 1.72 | 1.72 |
| 340.85 | 2.69 | 2.69 |
| 524.59 | ||
| 361.35 | 1.13 | 1.13 |
| 684.82 | 1.61 | 1.61 |
| 800.99 | 3.77 | 3.77 |
| 519.42 | 4.40 | 4.40 |
| 464.65 | 4.99 | 4.99 |
| 458.42 | 5.87 | 5.87 |
| 399.62 | 4.23 | 4.23 |