Basic Information
ID: ALA1613993
Type: ADME
Description: PUBCHEM_BIOASSAY: Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR). (Class of assay: confirmatory) [Related pubchem assays: 2796 (Primary screen (AHR activators in singlicate)), 2845 (Confirmation screen (AHR activators in triplicate)), 434939 (Counterscreen (PXR activators in triplicate)), 2804 (Summary (AHR activators))]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1613993
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.78 | 1.79 | 1.79 |
| 282.34 | 2.39 | 2.39 |
| 293.33 | 3.30 | 3.30 |
| 350.38 | 1.92 | 1.92 |
| 313.27 | 2.12 | 2.12 |
| 253.33 | 3.95 | 3.95 |
| 235.67 | 2.69 | 2.69 |
| 383.50 | 1.56 | 1.56 |
| 318.18 | 3.25 | 3.25 |
| 271.32 | 3.26 | 3.26 |
| 293.33 | 3.28 | 3.28 |
| 205.21 | 2.19 | 2.19 |
| 379.37 | 2.12 | 2.12 |
| 251.27 | 1.89 | 1.89 |
| 286.34 | 3.79 | 3.79 |
| 396.40 | 3.81 | 3.81 |
| 242.23 | 2.06 | 2.06 |
| 249.29 | 2.17 | 2.17 |
| 282.13 | 4.03 | 4.03 |
| 279.34 | 4.26 | 4.26 |
| 378.21 | 4.07 | 4.07 |
| 315.29 | 2.08 | 2.08 |
| 299.30 | 3.76 | 3.76 |
| 294.31 | 2.75 | 2.75 |
| 320.72 | 4.38 | 4.38 |
| 407.99 | 4.75 | 4.75 |
| 320.31 | 1.12 | 1.12 |
| 262.25 | 1.00 | 1.00 |
| 282.30 | 2.23 | 2.23 |
| 293.80 | 4.66 | 4.66 |
| 281.38 | 4.19 | 4.19 |
| 324.77 | 4.34 | 4.34 |
| 319.79 | 2.17 | 2.17 |
| 299.81 | 3.23 | 3.23 |
| 272.34 | 1.80 | 1.80 |
| 232.24 | 2.84 | 2.84 |
| 300.75 | 3.97 | 3.97 |
| 298.32 | 3.46 | 3.46 |
| 392.38 | 3.49 | 3.49 |
| 386.23 | 5.46 | 5.46 |
| 285.35 | 2.47 | 2.47 |
| 327.41 | 2.81 | 2.81 |
| 356.22 | 4.86 | 4.86 |
| 332.79 | 3.58 | 3.58 |
| 256.33 | 3.82 | 3.82 |
| 264.24 | 2.07 | 2.07 |
| 327.82 | 4.43 | 4.43 |
| 256.72 | 2.09 | 2.09 |
| 313.59 | 3.53 | 3.53 |
| 266.26 | 1.53 | 1.53 |
| 349.43 | 3.58 | 3.58 |
| 328.37 | 3.30 | 3.30 |
| 385.92 | 4.56 | 4.56 |
| 385.27 | 3.97 | 3.97 |
| 377.40 | 3.60 | 3.60 |
| 387.72 | 3.34 | 3.34 |
| 310.35 | 3.64 | 3.64 |
| 272.74 | 2.96 | 2.96 |
| 424.50 | 4.93 | 4.93 |
| 259.27 | 1.31 | 1.31 |
| 270.21 | 2.26 | 2.26 |
| 351.82 | 3.41 | 3.41 |
| 309.37 | 2.11 | 2.11 |
| 272.73 | 2.70 | 2.70 |
| 296.33 | 2.20 | 2.20 |
| 237.26 | 3.11 | 3.11 |
| 295.64 | 2.69 | 2.69 |
| 342.78 | 4.27 | 4.27 |
| 296.37 | 3.41 | 3.41 |
| 337.40 | 2.39 | 2.39 |
| 291.35 | 4.41 | 4.41 |
| 348.34 | 2.36 | 2.36 |
| 284.34 | 2.45 | 2.45 |
| 310.40 | 3.94 | 3.94 |
| 293.78 | 3.41 | 3.41 |
| 247.30 | 3.58 | 3.58 |
| 282.35 | 3.17 | 3.17 |
| 340.32 | 2.71 | 2.71 |
| 302.31 | 2.80 | 2.80 |
| 385.10 | 3.24 | 3.24 |
| 227.27 | 2.23 | 2.23 |
| 431.99 | 3.32 | 3.32 |
| 346.39 | 5.55 | 5.55 |
| 298.27 | 2.92 | 2.92 |
| 233.66 | 2.38 | 2.38 |
| 246.33 | 3.26 | 3.26 |
| 283.35 | 2.79 | 2.79 |
| 313.23 | 2.62 | 2.62 |
| 243.27 | 2.73 | 2.73 |
| 357.41 | 4.87 | 4.87 |
| 279.30 | 1.39 | 1.39 |
| 343.77 | 2.17 | 2.17 |
| 322.35 | 1.48 | 1.48 |
| 327.41 | 3.64 | 3.64 |
| 321.38 | 4.50 | 4.50 |
| 240.26 | 2.68 | 2.68 |
| 298.18 | 3.74 | 3.74 |
| 281.32 | 2.73 | 2.73 |
| 255.32 | 1.85 | 1.85 |
| 249.66 | 2.09 | 2.09 |
| 383.46 | 2.68 | 2.68 |
| 316.15 | 4.01 | 4.01 |
| 321.34 | 2.46 | 2.46 |
| 340.41 | 3.14 | 3.14 |
| 299.71 | 3.83 | 3.83 |
| 382.42 | 3.35 | 3.35 |
| 389.41 | 3.42 | 3.42 |
| 306.75 | 1.59 | 1.59 |
| 296.33 | 3.03 | 3.03 |
| 299.42 | 4.09 | 4.09 |
| 322.36 | 3.63 | 3.63 |
| 271.30 | 3.25 | 3.25 |
| 348.37 | 2.93 | 2.93 |
| 465.44 | 3.56 | 3.56 |
| 299.29 | 1.58 | 1.58 |
| 341.37 | 3.78 | 3.78 |
| 323.42 | 4.12 | 4.12 |
| 298.37 | 3.01 | 3.01 |
| 340.30 | 1.99 | 1.99 |
| 291.35 | 4.00 | 4.00 |
| 309.34 | 4.14 | 4.14 |
| 415.20 | 3.78 | 3.78 |
| 310.31 | 2.81 | 2.81 |
| 305.34 | 2.42 | 2.42 |
| 313.18 | 2.76 | 2.76 |
| 268.74 | 4.38 | 4.38 |