Basic Information
ID: ALA1614006
Type: Binding
Description: PUBCHEM_BIOASSAY: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). (Class of assay: confirmatory) [Related PubChem assays: 2170 (Confirmation screen (PFM18AAP inhibitors).), 1855 (Summary AID.)]
Organism: Plasmodium falciparum 3D7
Strain: 3D7
Activity Charts
Bioactivity
Activity Types for Assay ALA1614006
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.33 | 2.85 | 2.85 |
| 154.12 | 0.80 | 0.80 |
| 179.18 | 0.81 | 0.81 |
| 228.25 | 2.97 | 2.97 |
| 292.32 | 1.88 | 1.88 |
| 328.35 | 2.72 | 2.72 |
| 189.64 | 0.60 | 0.60 |
| 207.25 | 2.53 | 2.53 |
| 290.27 | 1.55 | 1.55 |
| 320.25 | 1.99 | 1.99 |
| 333.29 | 0.35 | 0.35 |
| 417.37 | 3.06 | 3.06 |
| 279.25 | 1.01 | 1.01 |
| 271.20 | 2.07 | 2.07 |
| 364.36 | 0.80 | 0.80 |
| 284.28 | 2.45 | 2.45 |
| 354.71 | 2.66 | 2.66 |
| 259.31 | 3.50 | 3.50 |
| 415.45 | 2.37 | 2.37 |
| 194.22 | 1.62 | 1.62 |
| 291.22 | 1.38 | 1.38 |
| 270.31 | 3.28 | 3.28 |
| 214.22 | 1.79 | 1.79 |
| 241.32 | 3.36 | 3.36 |
| 373.72 | 3.22 | 3.22 |
| 165.24 | 2.49 | 2.49 |
| 361.36 | 2.06 | 2.06 |
| 259.29 | 1.75 | 1.75 |
| 350.43 | 2.70 | 2.70 |
| 379.44 | 1.73 | 1.73 |
| 309.33 | 2.11 | 2.11 |
| 316.24 | 1.54 | 1.54 |
| 311.14 | 1.50 | 1.50 |
| 251.68 | 2.02 | 2.02 |
| 246.26 | 3.00 | 3.00 |
| 350.45 | 2.12 | 2.12 |
| 299.28 | 1.77 | 1.77 |
| 307.34 | 0.55 | 0.55 |
| 302.32 | 1.19 | 1.19 |
| 331.31 | 2.93 | 2.93 |
| 242.24 | 1.72 | 1.72 |
| 214.23 | 1.06 | 1.06 |
| 303.79 | 2.85 | 2.85 |
| 248.20 | 0.96 | 0.96 |
| 363.68 | 3.45 | 3.45 |
| 388.46 | 3.91 | 3.91 |
| 264.29 | 2.33 | 2.33 |
| 314.34 | 1.19 | 1.19 |
| 345.30 | 3.26 | 3.26 |
| 387.40 | 5.04 | 5.04 |
| 318.31 | 0.69 | 0.69 |
| 288.39 | 3.31 | 3.31 |
| 272.10 | 2.36 | 2.36 |
| 394.64 | 2.21 | 2.21 |
| 375.38 | 1.90 | 1.90 |
| 315.33 | 1.60 | 1.60 |
| 275.27 | 1.23 | 1.23 |
| 388.51 | 3.54 | 3.54 |
| 366.85 | 4.45 | 4.45 |
| 331.34 | 2.05 | 2.05 |
| 272.10 | 2.36 | 2.36 |
| 255.64 | 1.85 | 1.85 |
| 345.36 | 2.36 | 2.36 |
| 175.20 | 0.74 | 0.74 |
| 316.55 | 2.47 | 2.47 |
| 330.30 | -0.15 | -0.15 |
| 327.25 | 3.55 | 3.55 |
| 310.34 | 0.09 | 0.09 |
| 318.39 | 2.05 | 2.05 |
| 244.28 | 1.88 | 1.88 |
| 247.33 | 2.06 | 2.06 |
| 345.36 | 2.89 | 2.89 |
| 374.32 | 2.22 | 2.22 |
| 180.13 | -0.92 | -0.92 |
| 269.33 | 3.89 | 3.89 |
| 278.23 | 0.97 | 0.97 |
| 271.30 | 1.08 | 1.08 |
| 248.20 | 0.96 | 0.96 |
| 237.65 | 1.71 | 1.71 |
| 267.68 | 1.72 | 1.72 |
| 159.17 | -0.02 | -0.02 |
| 315.74 | 0.84 | 0.84 |
| 294.30 | 1.36 | 1.36 |
| 315.16 | 2.67 | 2.67 |
| 323.38 | 0.69 | 0.69 |
| 450.44 | 1.88 | 1.88 |
| 226.24 | 2.41 | 2.41 |
| 272.10 | 2.36 | 2.36 |
| 340.69 | 2.27 | 2.27 |
| 180.24 | 1.03 | 1.03 |
| 288.16 | 2.53 | 2.53 |
| 377.42 | 2.97 | 2.97 |
| 411.34 | 2.12 | 2.12 |
| 291.22 | 0.36 | 0.36 |
| 314.33 | 2.31 | 2.31 |
| 321.38 | 3.28 | 3.28 |
| 326.18 | 1.30 | 1.30 |
| 247.33 | 2.00 | 2.00 |
| 345.36 | 2.36 | 2.36 |
| 247.33 | 2.06 | 2.06 |
| 346.37 | 3.57 | 3.57 |
| 330.75 | 0.43 | 0.43 |
| 218.22 | 0.56 | 0.56 |
| 296.31 | -0.22 | -0.22 |
| 224.25 | 0.21 | 0.21 |
| 272.10 | 2.36 | 2.36 |
| 267.75 | 2.40 | 2.40 |
| 265.23 | 0.96 | 0.96 |
| 395.35 | 1.29 | 1.29 |
| 284.34 | 2.70 | 2.70 |
| 251.68 | 2.02 | 2.02 |
| 216.24 | 1.17 | 1.17 |
| 314.34 | 3.24 | 3.24 |
| 234.28 | 2.07 | 2.07 |
| 516.46 | 1.03 | 1.03 |
| 272.26 | 1.96 | 1.96 |
| 397.46 | 3.21 | 3.21 |
| 464.43 | 1.80 | 1.80 |
| 397.46 | 3.21 | 3.21 |
| 330.30 | 1.18 | 1.18 |
| 348.24 | 4.91 | 4.91 |
| 277.13 | 2.55 | 2.55 |
| 239.19 | -0.47 | -0.47 |
| 204.19 | 0.57 | 0.57 |
| 297.11 | 2.03 | 2.03 |