Basic Information
ID: ALA1614007
Type: Functional
Description: PUBCHEM_BIOASSAY: Concentration response confirmation VP16 counterscreen for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) [Related pubchem assays: 2546 (Primary counterscreen tested in the VP16 cell line at 6 concentrations from 46 uM to 3 nM)]
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1614007
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.25 | 2.97 | 2.97 |
| 456.71 | 7.09 | 7.09 |
| 333.39 | 4.18 | 4.18 |
| 207.25 | 2.53 | 2.53 |
| 193.17 | -1.63 | -1.63 |
| 387.35 | 4.24 | 4.24 |
| 320.22 | 2.94 | 2.94 |
| 376.47 | 2.92 | 2.92 |
| 349.35 | 3.38 | 3.38 |
| 364.86 | 3.20 | 3.20 |
| 302.28 | 2.15 | 2.15 |
| 303.41 | 4.33 | 4.33 |
| 278.32 | 2.32 | 2.32 |
| 373.43 | 4.97 | 4.97 |
| 339.44 | 4.34 | 4.34 |
| 290.39 | 2.49 | 2.49 |
| 336.44 | 2.61 | 2.61 |
| 516.65 | 2.07 | 2.07 |
| 383.45 | 4.82 | 4.82 |
| 379.44 | 3.82 | 3.82 |
| 350.42 | 4.00 | 4.00 |
| 439.51 | 4.27 | 4.27 |
| 411.46 | 0.56 | 0.56 |
| 384.87 | 3.97 | 3.97 |
| 364.49 | 4.07 | 4.07 |
| 300.34 | 2.74 | 2.74 |
| 344.46 | 5.29 | 5.29 |
| 335.41 | 4.09 | 4.09 |
| 443.62 | 3.22 | 3.22 |
| 370.48 | 5.39 | 5.39 |
| 259.19 | 2.55 | 2.55 |
| 429.86 | 2.35 | 2.35 |
| 339.40 | 3.76 | 3.76 |
| 360.44 | 2.56 | 2.56 |
| 527.70 | 4.07 | 4.07 |
| 326.27 | 2.51 | 2.51 |
| 381.44 | 2.60 | 2.60 |
| 364.45 | 2.88 | 2.88 |
| 348.40 | 3.67 | 3.67 |
| 437.43 | 4.57 | 4.57 |
| 348.40 | 2.69 | 2.69 |
| 475.57 | 1.83 | 1.83 |
| 357.44 | 2.06 | 2.06 |
| 251.28 | 3.99 | 3.99 |
| 376.46 | 3.28 | 3.28 |
| 331.37 | -0.01 | -0.01 |
| 524.46 | 3.30 | 3.30 |
| 360.84 | 2.84 | 2.84 |
| 397.48 | 2.13 | 2.13 |
| 325.37 | 3.61 | 3.61 |
| 349.83 | 4.37 | 4.37 |
| 370.35 | 4.28 | 4.28 |
| 305.38 | 4.08 | 4.08 |
| 293.43 | 3.40 | 3.40 |
| 350.49 | 4.49 | 4.49 |
| 326.38 | 3.89 | 3.89 |
| 234.26 | 1.30 | 1.30 |
| 437.97 | 5.16 | 5.16 |
| 279.35 | 1.53 | 1.53 |
| 417.94 | 4.36 | 4.36 |
| 390.26 | 3.76 | 3.76 |
| 360.49 | 5.03 | 5.03 |
| 419.46 | 4.17 | 4.17 |
| 341.38 | 2.72 | 2.72 |
| 427.53 | 3.00 | 3.00 |
| 329.38 | 2.83 | 2.83 |
| 380.92 | 3.55 | 3.55 |
| 409.96 | 2.71 | 2.71 |
| 313.36 | 4.79 | 4.79 |
| 398.42 | 4.55 | 4.55 |
| 314.34 | 4.57 | 4.57 |
| 405.59 | 6.20 | 6.20 |
| 268.34 | 3.50 | 3.50 |
| 397.44 | 0.17 | 0.17 |
| 330.45 | 3.72 | 3.72 |
| 378.54 | 5.11 | 5.11 |
| 489.59 | 2.22 | 2.22 |
| 399.84 | 2.34 | 2.34 |
| 256.31 | 4.45 | 4.45 |
| 440.51 | 3.83 | 3.83 |
| 426.45 | 1.72 | 1.72 |
| 302.29 | 3.82 | 3.82 |
| 528.87 | 5.09 | 5.09 |
| 297.76 | 3.62 | 3.62 |
| 544.94 | 4.42 | 4.42 |
| 411.46 | 2.87 | 2.87 |
| 329.38 | 2.83 | 2.83 |
| 300.37 | 3.95 | 3.95 |
| 365.43 | 3.77 | 3.77 |
| 343.34 | 3.12 | 3.12 |
| 240.21 | 1.02 | 1.02 |
| 452.67 | 4.52 | 4.52 |
| 254.22 | 2.60 | 2.60 |
| 359.29 | 4.84 | 4.84 |
| 452.67 | 4.52 | 4.52 |
| 277.33 | 2.79 | 2.79 |
| 301.42 | 2.36 | 2.36 |
| 357.36 | 2.69 | 2.69 |
| 413.36 | 4.48 | 4.48 |
| 398.89 | 3.17 | 3.17 |
| 359.41 | 4.58 | 4.58 |
| 347.38 | 3.11 | 3.11 |
| 301.39 | 3.10 | 3.10 |
| 474.58 | 3.27 | 3.27 |
| 388.47 | 5.53 | 5.53 |
| 410.52 | 1.56 | 1.56 |
| 271.10 | 2.55 | 2.55 |
| 371.37 | 2.54 | 2.54 |
| 351.46 | 5.67 | 5.67 |
| 419.33 | 4.09 | 4.09 |
| 446.58 | 4.05 | 4.05 |
| 395.53 | 4.14 | 4.14 |
| 283.83 | 3.03 | 3.03 |
| 372.40 | 3.34 | 3.34 |
| 331.42 | 3.89 | 3.89 |
| 485.54 | 4.06 | 4.06 |
| 301.77 | 3.66 | 3.66 |
| 353.41 | 2.68 | 2.68 |
| 260.34 | 1.97 | 1.97 |
| 444.47 | 0.07 | 0.07 |
| 351.44 | 2.92 | 2.92 |
| 373.61 | 5.58 | 5.58 |
| 266.30 | 3.46 | 3.46 |
| 381.43 | 3.44 | 3.44 |
| 294.31 | 3.22 | 3.22 |
| 348.23 | 3.26 | 3.26 |
| 338.37 | 3.17 | 3.17 |
| 656.66 | 2.75 | 2.75 |
| 489.59 | 2.13 | 2.13 |
| 320.41 | 1.88 | 1.88 |
| 224.65 | 1.32 | 1.32 |
| 261.31 | 2.53 | 2.53 |
| 374.49 | 3.55 | 3.55 |
| 272.30 | 3.36 | 3.36 |
| 309.32 | 3.36 | 3.36 |
| 266.30 | 3.62 | 3.62 |
| 276.36 | 3.03 | 3.03 |
| 286.36 | 1.67 | 1.67 |
| 318.36 | 4.09 | 4.09 |
| 397.48 | 5.12 | 5.12 |
| 447.52 | 4.86 | 4.86 |
| 262.33 | 1.87 | 1.87 |
| 384.49 | 4.37 | 4.37 |
| 301.44 | 3.90 | 3.90 |
| 395.42 | 1.70 | 1.70 |
| 356.84 | 4.41 | 4.41 |
| 322.36 | 3.92 | 3.92 |
| 437.59 | 2.90 | 2.90 |
| 374.40 | 3.84 | 3.84 |
| 305.77 | 4.51 | 4.51 |
| 496.61 | 3.82 | 3.82 |
| 307.42 | 4.34 | 4.34 |
| 385.84 | 4.34 | 4.34 |
| 488.39 | 3.79 | 3.79 |