Basic Information
ID: ALA1614034
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Antagonists for Thrombopoietin (TPO) Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 917 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614034
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 391.56 | 6.86 | 6.86 |
| 167.30 | 2.42 | 2.42 |
| 168.15 | 1.22 | 1.22 |
| 314.86 | 4.53 | 4.53 |
| 407.51 | 4.95 | 4.95 |
| 270.24 | 2.58 | 2.58 |
| 263.38 | 3.83 | 3.83 |
| 393.47 | 4.51 | 4.51 |
| 270.24 | 2.58 | 2.58 |
| 329.36 | 4.06 | 4.06 |
| 254.24 | 2.87 | 2.87 |
| 184.96 | -0.09 | -0.09 |
| 375.87 | 4.43 | 4.43 |
| 125.13 | -0.07 | -0.07 |
| 272.18 | 3.33 | 3.33 |
| 444.49 | -0.14 | -0.14 |
| 153.18 | 0.60 | 0.60 |
| 348.36 | 2.08 | 2.08 |
| 301.33 | 3.03 | 3.03 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 376.50 | 4.72 | 4.72 |
| 473.59 | 6.08 | 6.08 |
| 853.92 | 3.74 | 3.74 |
| 284.32 | 1.59 | 1.59 |
| 160.18 | 0.92 | 0.92 |
| 259.35 | 2.58 | 2.58 |
| 125.17 | 0.30 | 0.30 |
| 304.22 | 3.38 | 3.38 |
| 332.34 | 3.43 | 3.43 |
| 348.38 | 3.72 | 3.72 |
| 348.49 | 6.29 | 6.29 |
| 422.35 | 2.45 | 2.45 |
| 314.47 | 4.72 | 4.72 |
| 385.51 | 2.53 | 2.53 |
| 216.28 | 1.94 | 1.94 |
| 110.11 | 1.10 | 1.10 |
| 344.85 | 5.38 | 5.38 |
| 211.66 | 1.17 | 1.17 |
| 431.39 | 5.51 | 5.51 |
| 399.44 | 2.87 | 2.87 |
| 409.42 | 4.79 | 4.79 |
| 242.27 | 2.75 | 2.75 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 352.43 | 5.26 | 5.26 |
| 285.69 | 2.77 | 2.77 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 471.69 | 6.45 | 6.45 |
| 163.20 | -0.49 | -0.49 |
| 370.41 | 5.26 | 5.26 |
| 299.48 | 5.55 | 5.55 |
| 393.46 | 3.28 | 3.28 |
| 339.39 | 3.86 | 3.86 |
| 283.33 | 2.56 | 2.56 |
| 403.53 | 4.06 | 4.06 |
| 170.24 | 0.58 | 0.58 |
| 522.61 | 2.97 | 2.97 |
| 246.31 | 4.49 | 4.49 |
| 145.25 | -0.34 | -0.34 |
| 450.57 | 5.32 | 5.32 |
| 520.63 | 5.58 | 5.58 |
| 645.32 | 6.94 | 6.94 |
| 255.36 | 3.35 | 3.35 |
| 277.41 | 4.21 | 4.21 |
| 231.04 | 2.35 | 2.35 |
| 263.38 | 4.30 | 4.30 |
| 275.40 | 4.55 | 4.55 |
| 183.21 | 0.48 | 0.48 |
| 320.43 | 5.17 | 5.17 |
| 202.35 | -0.36 | -0.36 |
| 472.38 | 5.00 | 5.00 |
| 215.03 | 3.10 | 3.10 |
| 179.22 | 2.12 | 2.12 |
| 372.55 | 3.81 | 3.81 |
| 417.55 | 4.18 | 4.18 |
| 110.11 | 1.10 | 1.10 |
| 414.59 | 5.04 | 5.04 |
| 267.33 | 2.65 | 2.65 |
| 334.35 | 3.26 | 3.26 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 352.74 | 5.22 | 5.22 |
| 328.41 | 2.14 | 2.14 |
| 347.86 | 4.47 | 4.47 |
| 302.24 | 1.99 | 1.99 |
| 582.92 | 7.22 | 7.22 |
| 395.47 | 4.23 | 4.23 |
| 608.69 | 4.17 | 4.17 |
| 167.21 | 0.86 | 0.86 |
| 167.21 | 0.64 | 0.64 |
| 266.73 | 2.51 | 2.51 |
| 311.38 | 3.34 | 3.34 |
| 563.65 | 6.00 | 6.00 |
| 295.38 | 3.27 | 3.27 |
| 374.28 | 4.04 | 4.04 |
| 267.28 | 3.05 | 3.05 |
| 255.32 | 2.38 | 2.38 |
| 369.47 | 3.46 | 3.46 |
| 180.21 | 2.78 | 2.78 |
| 345.40 | 2.51 | 2.51 |
| 275.09 | 1.27 | 1.27 |
| 582.79 | 6.80 | 6.80 |
| 258.28 | 1.55 | 1.55 |
| 340.88 | 3.29 | 3.29 |
| 340.49 | 4.83 | 4.83 |
| 227.31 | 1.99 | 1.99 |
| 1429.19 | ||
| 329.44 | 3.26 | 3.26 |
| 270.24 | 1.89 | 1.89 |
| 477.05 | 5.09 | 5.09 |
| 292.34 | 3.17 | 3.17 |
| 434.53 | 4.60 | 4.60 |
| 475.58 | 5.31 | 5.31 |
| 334.42 | 2.38 | 2.38 |
| 370.46 | 5.59 | 5.59 |
| 264.33 | 3.25 | 3.25 |
| 495.64 | 5.27 | 5.27 |
| 217.28 | 1.72 | 1.72 |
| 247.32 | 2.39 | 2.39 |
| 274.18 | ||
| 327.18 | 4.09 | 4.09 |
| 75.07 | -1.47 | -1.47 |
| 225.25 | 2.03 | 2.03 |
| 267.33 | 2.85 | 2.85 |
| 494.08 | 8.01 | 8.01 |
| 504.64 | -0.02 | -0.02 |
| 294.31 | 2.32 | 2.32 |
| 297.27 | 2.30 | 2.30 |
| 308.34 | 2.36 | 2.36 |
| 322.36 | 2.75 | 2.75 |
| 340.85 | 4.30 | 4.30 |
| 418.28 | 3.49 | 3.49 |
| 152.29 | 0.29 | 0.29 |
| 270.21 | 3.25 | 3.25 |
| 296.55 | 3.62 | 3.62 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 287.79 | 3.67 | 3.67 |
| 193.25 | 2.79 | 2.79 |
| 318.24 | 1.69 | 1.69 |
| 436.62 | 7.51 | 7.51 |
| 304.31 | 3.37 | 3.37 |
| 382.89 | 4.89 | 4.89 |
| 465.38 | 4.29 | 4.29 |
| 220.25 | 0.77 | 0.77 |
| 202.17 | 1.23 | 1.23 |
| 186.17 | 1.53 | 1.53 |
| 282.39 | 4.42 | 4.42 |
| 381.55 | 5.16 | 5.16 |
| 287.32 | 3.10 | 3.10 |
| 228.25 | 2.97 | 2.97 |
| 304.39 | 3.15 | 3.15 |
| 302.37 | 3.57 | 3.57 |
| 303.41 | 4.89 | 4.89 |
| 286.36 | 3.59 | 3.59 |
| 314.37 | 2.26 | 2.26 |
| 293.37 | 3.41 | 3.41 |
| 295.38 | 3.63 | 3.63 |
| 313.79 | 3.43 | 3.43 |
| 307.35 | 3.30 | 3.30 |
| 380.50 | 3.12 | 3.12 |
| 391.47 | 4.88 | 4.88 |
| 309.49 | 4.40 | 4.40 |
| 134.14 | 0.15 | 0.15 |
| 371.22 | 4.05 | 4.05 |
| 176.31 | 1.17 | 1.17 |
| 131.18 | 1.00 | 1.00 |
| 327.34 | 3.05 | 3.05 |
| 346.47 | 2.67 | 2.67 |
| 331.76 | 3.21 | 3.21 |
| 137.12 | 0.24 | 0.24 |
| 359.73 | 2.43 | 2.43 |
| 456.68 | 6.17 | 6.17 |
| 386.45 | 5.28 | 5.28 |
| 135.17 | 0.55 | 0.55 |
| 604.70 | 3.54 | 3.54 |
| 277.28 | 4.42 | 4.42 |
| 179.22 | 0.42 | 0.42 |
| 187.16 | 0.85 | 0.85 |
| 266.34 | 0.45 | 0.45 |
| 251.31 | 0.47 | 0.47 |
| 292.21 | 4.79 | 4.79 |
| 168.15 | 0.72 | 0.72 |
| 531.44 | 4.21 | 4.21 |
| 336.33 | -1.72 | -1.72 |
| 91.07 | -1.04 | -1.04 |
| 267.36 | 3.13 | 3.13 |
| 356.18 | 5.18 | 5.18 |
| 434.71 | 4.01 | 4.01 |
| 430.54 | 2.72 | 2.72 |
| 592.69 | 2.88 | 2.88 |
| 169.57 | 1.77 | 1.77 |
| 254.29 | 3.11 | 3.11 |
| 86.09 | 0.16 | 0.16 |
| 176.22 | 1.37 | 1.37 |
| 279.10 | -0.20 | -0.20 |
| 319.76 | 0.54 | 0.54 |
| 461.56 | 5.86 | 5.86 |
| 130.08 | -0.80 | -0.80 |
| 476.79 | 4.68 | 4.68 |
| 327.12 | 3.86 | 3.86 |
| 276.68 | 3.50 | 3.50 |
| 178.14 | 1.20 | 1.20 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 312.82 | 2.51 | 2.51 |
| 446.37 | 3.58 | 3.58 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 278.40 | 3.92 | 3.92 |
| 346.34 | 2.18 | 2.18 |
| 147.27 | 1.30 | 1.30 |
| 384.26 | 3.96 | 3.96 |
| 305.21 | 1.93 | 1.93 |
| 360.37 | 2.57 | 2.57 |
| 213.24 | 3.51 | 3.51 |
| 195.26 | 3.56 | 3.56 |
| 292.45 | 2.80 | 2.80 |
| 395.54 | 4.55 | 4.55 |
| 241.25 | 1.91 | 1.91 |
| 249.34 | 3.06 | 3.06 |
| 308.34 | 2.88 | 2.88 |
| 308.34 | 2.88 | 2.88 |
| 218.21 | 1.57 | 1.57 |
| 217.29 | 0.63 | 0.63 |
| 165.24 | 1.33 | 1.33 |
| 383.40 | 2.87 | 2.87 |
| 343.90 | 5.10 | 5.10 |
| 311.78 | 0.72 | 0.72 |
| 244.21 | -3.01 | -3.01 |
| 311.34 | 3.21 | 3.21 |
| 299.77 | 0.57 | 0.57 |
| 207.32 | 2.67 | 2.67 |
| 365.83 | 3.33 | 3.33 |
| 342.70 | 5.18 | 5.18 |
| 381.99 | 3.57 | 3.57 |
| 316.47 | 4.18 | 4.18 |
| 357.16 | ||
| 496.68 | 3.80 | 3.80 |
| 388.65 | 1.85 | 1.85 |
| 217.30 | 2.18 | 2.18 |
| 331.46 | 5.32 | 5.32 |
| 309.45 | 4.20 | 4.20 |
| 452.56 | 3.91 | 3.91 |
| 414.37 | 3.05 | 3.05 |
| 603.76 | 4.11 | 4.11 |
| 179.22 | 0.91 | 0.91 |
| 305.76 | 2.73 | 2.73 |
| 205.28 | 0.07 | 0.07 |
| 309.33 | 4.44 | 4.44 |
| 328.36 | 4.43 | 4.43 |
| 247.34 | 2.17 | 2.17 |
| 226.23 | -0.05 | -0.05 |
| 522.62 | 4.60 | 4.60 |
| 115.13 | -0.03 | -0.03 |
| 214.22 | 0.73 | 0.73 |
| 175.14 | 2.19 | 2.19 |
| 256.74 | 3.48 | 3.48 |
| 272.35 | 2.81 | 2.81 |
| 321.23 | 1.73 | 1.73 |
| 161.16 | -0.78 | -0.78 |
| 299.77 | 0.22 | 0.22 |
| 235.34 | 2.95 | 2.95 |
| 213.19 | -0.24 | -0.24 |
| 349.40 | 3.65 | 3.65 |
| 300.31 | 3.34 | 3.34 |
| 401.84 | 1.07 | 1.07 |
| 514.53 | -0.14 | -0.14 |
| 373.39 | 1.95 | 1.95 |
| 333.29 | 0.35 | 0.35 |
| 512.79 | 7.73 | 7.73 |
| 452.67 | 4.40 | 4.40 |
| 810.99 | 3.99 | 3.99 |
| 243.22 | -2.56 | -2.56 |
| 602.59 | ||
| 286.40 | 3.70 | 3.70 |
| 456.50 | 1.53 | 1.53 |
| 186.16 | -0.05 | -0.05 |
| 289.76 | 3.03 | 3.03 |
| 404.50 | 5.39 | 5.39 |
| 438.58 | 5.32 | 5.32 |
| 341.45 | 3.24 | 3.24 |
| 325.45 | 3.14 | 3.14 |
| 211.22 | 0.14 | 0.14 |
| 277.35 | 0.83 | 0.83 |
| 516.55 | 5.40 | 5.40 |
| 414.41 | 2.41 | 2.41 |
| 836.39 | -2.45 | -2.45 |
| 548.66 | 6.84 | 6.84 |
| 246.22 | 1.93 | 1.93 |
| 327.43 | 5.74 | 5.74 |
| 269.34 | 2.72 | 2.72 |
| 199.64 | 1.29 | 1.29 |
| 650.76 | 3.93 | 3.93 |
| 491.65 | 5.96 | 5.96 |
| 168.15 | -0.14 | -0.14 |
| 248.32 | 2.76 | 2.76 |
| 319.27 | 0.09 | 0.09 |
| 216.28 | 1.77 | 1.77 |
| 370.59 | 5.89 | 5.89 |
| 242.34 | 3.12 | 3.12 |
| 699.61 | 2.88 | 2.88 |
| 172.19 | 0.80 | 0.80 |
| 357.88 | 4.06 | 4.06 |
| 824.97 | 3.52 | 3.52 |
| 840.12 | 3.85 | 3.85 |
| 301.39 | 2.96 | 2.96 |
| 465.80 | ||
| 261.92 | ||
| 230.31 | 2.68 | 2.68 |
| 414.51 | 3.57 | 3.57 |
| 650.78 | 3.28 | 3.28 |
| 218.30 | 1.76 | 1.76 |
| 339.44 | 3.25 | 3.25 |
| 281.27 | -1.52 | -1.52 |
| 357.49 | 3.34 | 3.34 |
| 523.63 | 5.53 | 5.53 |
| 256.26 | 2.70 | 2.70 |
| 481.48 | 3.98 | 3.98 |
| 302.41 | 3.97 | 3.97 |
| 264.50 | 3.11 | 3.11 |
| 284.31 | 2.90 | 2.90 |
| 875.11 | 5.60 | 5.60 |
| 394.49 | 4.04 | 4.04 |
| 319.25 | 3.93 | 3.93 |
| 750.71 | 3.19 | 3.19 |
| 204.23 | 0.83 | 0.83 |
| 405.50 | 3.58 | 3.58 |
| 341.88 | 5.07 | 5.07 |
| 318.50 | 4.60 | 4.60 |
| 629.56 | -0.98 | -0.98 |
| 299.36 | 1.52 | 1.52 |
| 317.82 | 3.68 | 3.68 |
| 428.44 | 2.54 | 2.54 |
| 299.39 | 3.09 | 3.09 |
| 357.45 | 1.71 | 1.71 |
| 294.44 | 4.12 | 4.12 |
| 480.65 | 4.94 | 4.94 |
| 213.23 | 0.33 | 0.33 |
| 249.34 | 2.80 | 2.80 |
| 329.83 | 3.93 | 3.93 |
| 399.97 | 5.97 | 5.97 |
| 255.36 | 3.72 | 3.72 |
| 520.72 | 4.21 | 4.21 |
| 343.34 | 0.18 | 0.18 |
| 588.56 | 1.69 | 1.69 |
| 234.25 | 0.80 | 0.80 |
| 312.45 | 4.64 | 4.64 |
| 299.50 | 3.92 | 3.92 |
| 268.32 | 2.72 | 2.72 |
| 335.42 | 1.91 | 1.91 |
| 370.42 | 2.45 | 2.45 |
| 315.87 | 5.19 | 5.19 |
| 599.31 | 1.43 | 1.43 |
| 305.37 | -0.45 | -0.45 |
| 300.05 | ||
| 338.23 | 4.02 | 4.02 |
| 707.85 | 2.72 | 2.72 |
| 544.74 | 1.06 | 1.06 |
| 257.25 | -1.76 | -1.76 |
| 301.52 | 4.15 | 4.15 |
| 265.31 | 1.64 | 1.64 |
| 694.37 | 2.49 | 2.49 |
| 317.18 | 4.50 | 4.50 |
| 376.58 | 5.66 | 5.66 |
| 361.53 | 4.84 | 4.84 |
| 302.41 | 3.62 | 3.62 |
| 196.20 | 0.64 | 0.64 |
| 508.45 | 5.68 | 5.68 |
| 371.40 | 0.09 | 0.09 |
| 555.66 | 4.26 | 4.26 |
| 418.45 | 2.97 | 2.97 |
| 497.50 | 1.02 | 1.02 |
| 394.42 | 3.70 | 3.70 |
| 429.60 | 5.41 | 5.41 |
| 349.39 | 0.18 | 0.18 |
| 283.19 | 2.91 | 2.91 |
| 385.90 | 3.93 | 3.93 |
| 310.46 | 5.07 | 5.07 |
| 337.46 | 4.22 | 4.22 |
| 225.20 | -1.63 | -1.63 |
| 275.30 | 1.29 | 1.29 |
| 287.75 | 4.00 | 4.00 |
| 274.80 | 3.82 | 3.82 |
| 293.35 | 0.26 | 0.26 |
| 385.51 | 1.20 | 1.20 |
| 365.84 | 2.98 | 2.98 |
| 403.37 | 5.73 | 5.73 |
| 308.34 | 2.37 | 2.37 |
| 301.69 | -1.33 | -1.33 |
| 244.24 | 3.42 | 3.42 |
| 348.24 | -0.34 | -0.34 |
| 652.26 | 10.29 | 10.29 |
| 358.36 | -0.24 | -0.24 |
| 479.53 | 3.68 | 3.68 |
| 349.57 | ||
| 244.25 | 2.68 | 2.68 |
| 186.26 | 2.01 | 2.01 |
| 220.23 | 4.43 | 4.43 |
| 800.99 | 3.77 | 3.77 |
| 464.65 | 4.99 | 4.99 |
| 280.36 | 2.11 | 2.11 |
| 616.84 | 5.75 | 5.75 |
| 458.42 | 5.87 | 5.87 |
| 399.62 | 4.23 | 4.23 |