Basic Information
ID: ALA1614065
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response to Identify Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4-C Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1827 (Project Summary), 1813 (Primary HTS)]
Activity Charts
Bioactivity
Activity Types for Assay ALA1614065
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.41 | 2.41 | 2.41 |
| 301.33 | 3.03 | 3.03 |
| 853.92 | 3.74 | 3.74 |
| 266.26 | -1.38 | -1.38 |
| 285.24 | -1.84 | -1.84 |
| 355.83 | 3.73 | 3.73 |
| 853.92 | 3.74 | 3.74 |
| 371.43 | 2.95 | 2.95 |
| 265.31 | 0.50 | 0.50 |
| 365.39 | 2.71 | 2.71 |
| 584.66 | -1.51 | -1.51 |
| 309.34 | 3.11 | 3.11 |
| 382.45 | 3.33 | 3.33 |
| 426.44 | 2.79 | 2.79 |
| 272.31 | 4.56 | 4.56 |
| 493.64 | 3.98 | 3.98 |
| 517.11 | 4.94 | 4.94 |
| 923.05 | 3.52 | 3.52 |
| 318.42 | 4.20 | 4.20 |
| 357.41 | 3.21 | 3.21 |
| 412.38 | 4.63 | 4.63 |
| 780.95 | 2.22 | 2.22 |
| 460.38 | 4.93 | 4.93 |
| 610.73 | 7.85 | 7.85 |
| 346.34 | 2.69 | 2.69 |
| 323.40 | 3.73 | 3.73 |
| 279.68 | -2.56 | -2.56 |
| 412.42 | 2.40 | 2.40 |
| 361.46 | 3.69 | 3.69 |
| 339.44 | 4.34 | 4.34 |
| 318.33 | 4.06 | 4.06 |
| 236.27 | 3.59 | 3.59 |
| 379.49 | 4.37 | 4.37 |
| 334.44 | 4.46 | 4.46 |
| 350.42 | 4.00 | 4.00 |
| 811.88 | 3.16 | 3.16 |
| 563.99 | 1.03 | 1.03 |
| 299.36 | 1.57 | 1.57 |
| 458.97 | 4.21 | 4.21 |
| 384.46 | 3.54 | 3.54 |
| 434.27 | 3.93 | 3.93 |
| 431.36 | 3.97 | 3.97 |
| 311.34 | 2.94 | 2.94 |
| 255.36 | 4.75 | 4.75 |
| 366.42 | 4.43 | 4.43 |
| 280.33 | 2.90 | 2.90 |
| 434.54 | 3.89 | 3.89 |
| 432.52 | 3.33 | 3.33 |
| 379.49 | 3.58 | 3.58 |
| 343.38 | 3.91 | 3.91 |
| 304.37 | 4.12 | 4.12 |
| 340.39 | 5.86 | 5.86 |
| 400.46 | 1.89 | 1.89 |
| 389.25 | 4.58 | 4.58 |
| 355.31 | 1.93 | 1.93 |
| 486.57 | 2.92 | 2.92 |
| 376.48 | 5.51 | 5.51 |
| 366.45 | 3.71 | 3.71 |
| 390.44 | 3.81 | 3.81 |
| 420.45 | 3.70 | 3.70 |
| 560.73 | 3.29 | 3.29 |
| 845.94 | 3.78 | 3.78 |
| 249.31 | 3.81 | 3.81 |
| 299.33 | 3.17 | 3.17 |
| 344.84 | 3.70 | 3.70 |
| 352.78 | 3.52 | 3.52 |
| 431.51 | 1.91 | 1.91 |
| 438.55 | 3.87 | 3.87 |
| 285.30 | 2.71 | 2.71 |
| 338.39 | 4.22 | 4.22 |
| 265.31 | 3.12 | 3.12 |
| 388.45 | 3.49 | 3.49 |
| 396.45 | 2.39 | 2.39 |
| 472.46 | 0.27 | 0.27 |
| 251.29 | 2.73 | 2.73 |
| 367.50 | 5.18 | 5.18 |
| 301.32 | 2.57 | 2.57 |
| 335.38 | 2.59 | 2.59 |
| 428.94 | 4.20 | 4.20 |
| 319.31 | 1.85 | 1.85 |
| 369.44 | 3.96 | 3.96 |
| 320.33 | 1.89 | 1.89 |
| 554.09 | 8.26 | 8.26 |
| 258.27 | 2.97 | 2.97 |
| 368.46 | 4.64 | 4.64 |
| 324.81 | 5.00 | 5.00 |
| 312.37 | 3.01 | 3.01 |
| 335.40 | 3.36 | 3.36 |
| 362.84 | 2.56 | 2.56 |
| 242.32 | 3.75 | 3.75 |
| 414.87 | 2.37 | 2.37 |
| 429.88 | 3.05 | 3.05 |
| 329.27 | 1.87 | 1.87 |
| 311.41 | 3.92 | 3.92 |
| 315.35 | 2.02 | 2.02 |
| 414.42 | 4.71 | 4.71 |
| 342.41 | 4.30 | 4.30 |
| 274.32 | 2.03 | 2.03 |
| 401.41 | 5.62 | 5.62 |
| 279.30 | 4.36 | 4.36 |
| 392.46 | 3.38 | 3.38 |
| 280.28 | 3.41 | 3.41 |
| 303.41 | 3.65 | 3.65 |
| 391.38 | 3.45 | 3.45 |
| 405.45 | 3.09 | 3.09 |
| 402.48 | 3.80 | 3.80 |
| 339.27 | 3.59 | 3.59 |
| 386.84 | 3.11 | 3.11 |
| 268.31 | 3.45 | 3.45 |
| 370.21 | 3.02 | 3.02 |
| 831.91 | 3.39 | 3.39 |
| 320.39 | 4.48 | 4.48 |
| 293.67 | 2.19 | 2.19 |
| 847.95 | 4.00 | 4.00 |
| 351.44 | 3.59 | 3.59 |
| 567.48 | 7.30 | 7.30 |
| 333.44 | 2.59 | 2.59 |
| 438.55 | 3.87 | 3.87 |
| 304.35 | 2.30 | 2.30 |
| 401.29 | 3.28 | 3.28 |
| 320.37 | 2.22 | 2.22 |
| 490.54 | 3.74 | 3.74 |
| 351.47 | 4.66 | 4.66 |
| 404.50 | 4.01 | 4.01 |
| 215.30 | 2.96 | 2.96 |
| 325.41 | 3.95 | 3.95 |
| 405.48 | 4.46 | 4.46 |
| 289.34 | 4.22 | 4.22 |
| 337.40 | 2.90 | 2.90 |
| 237.26 | 3.04 | 3.04 |
| 309.42 | 4.37 | 4.37 |
| 401.33 | 4.82 | 4.82 |
| 301.34 | 3.46 | 3.46 |
| 425.31 | 3.98 | 3.98 |
| 622.71 | 3.15 | 3.15 |
| 329.40 | 4.18 | 4.18 |
| 354.31 | 3.02 | 3.02 |
| 268.27 | 2.62 | 2.62 |
| 342.44 | 3.79 | 3.79 |
| 359.45 | 4.21 | 4.21 |
| 373.39 | 1.88 | 1.88 |
| 329.31 | 3.22 | 3.22 |
| 414.48 | 4.27 | 4.27 |
| 253.28 | 3.64 | 3.64 |
| 289.38 | 3.14 | 3.14 |
| 439.88 | 4.92 | 4.92 |
| 354.41 | 3.97 | 3.97 |
| 441.90 | 3.73 | 3.73 |
| 322.36 | 3.89 | 3.89 |
| 390.44 | 3.68 | 3.68 |
| 273.34 | 2.45 | 2.45 |
| 360.46 | 3.81 | 3.81 |
| 398.49 | 5.07 | 5.07 |
| 382.53 | 5.23 | 5.23 |
| 353.20 | 2.46 | 2.46 |
| 396.47 | 3.72 | 3.72 |
| 253.28 | 3.64 | 3.64 |
| 272.30 | 3.36 | 3.36 |
| 338.44 | 3.44 | 3.44 |
| 225.29 | 3.12 | 3.12 |
| 353.38 | 4.08 | 4.08 |
| 308.39 | 2.92 | 2.92 |
| 335.39 | 1.75 | 1.75 |
| 354.84 | 3.31 | 3.31 |
| 372.45 | 3.26 | 3.26 |
| 459.63 | 3.57 | 3.57 |
| 337.38 | 3.34 | 3.34 |
| 318.17 | 3.00 | 3.00 |
| 280.36 | 1.96 | 1.96 |
| 406.47 | 3.81 | 3.81 |
| 388.85 | 4.88 | 4.88 |
| 297.39 | 3.54 | 3.54 |
| 348.83 | 4.49 | 4.49 |
| 298.37 | 3.46 | 3.46 |
| 378.35 | 1.16 | 1.16 |
| 504.35 | 1.70 | 1.70 |
| 406.47 | 4.04 | 4.04 |
| 324.34 | 2.21 | 2.21 |
| 346.35 | 2.94 | 2.94 |
| 402.31 | 5.54 | 5.54 |
| 351.41 | 2.56 | 2.56 |
| 358.43 | 4.12 | 4.12 |
| 493.64 | 3.88 | 3.88 |