Basic Information
ID: ALA1614128
Type: Binding
Description: PUBCHEM_BIOASSAY: Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay. Confirmatory Screen for inhibitors of association between Mint1-PDZ domains and N-type Ca2+ channel carboxyl-terminal peptide (NC peptide). (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1614128
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 210.24 | 1.95 | 1.95 |
| 151.19 | 1.59 | 1.59 |
| 236.18 | 1.71 | 1.71 |
| 228.73 | 3.09 | 3.09 |
| 318.81 | 3.12 | 3.12 |
| 287.10 | 2.77 | 2.77 |
| 388.28 | 1.20 | 1.20 |
| 285.25 | 3.48 | 3.48 |
| 386.41 | 3.98 | 3.98 |
| 346.34 | 2.18 | 2.18 |
| 578.61 | 5.01 | 5.01 |
| 610.57 | -1.16 | -1.16 |
| 286.28 | 2.82 | 2.82 |
| 322.39 | 4.22 | 4.22 |
| 324.41 | 4.28 | 4.28 |
| 475.39 | 1.62 | 1.62 |
| 402.41 | 4.79 | 4.79 |
| 310.40 | 1.25 | 1.25 |
| 428.50 | 1.75 | 1.75 |
| 430.33 | 4.57 | 4.57 |
| 299.72 | 4.31 | 4.31 |
| 482.49 | 5.55 | 5.55 |
| 431.54 | 2.81 | 2.81 |
| 422.49 | 2.28 | 2.28 |
| 457.58 | 2.54 | 2.54 |
| 421.33 | 1.85 | 1.85 |
| 369.76 | 3.27 | 3.27 |
| 526.91 | 4.70 | 4.70 |
| 302.33 | 1.46 | 1.46 |
| 397.78 | 3.43 | 3.43 |
| 247.32 | 2.69 | 2.69 |
| 373.41 | 4.82 | 4.82 |
| 428.47 | 1.91 | 1.91 |
| 409.45 | 3.54 | 3.54 |
| 343.41 | 2.82 | 2.82 |
| 392.44 | 5.01 | 5.01 |
| 521.37 | 5.67 | 5.67 |
| 370.39 | 0.94 | 0.94 |
| 366.23 | 4.55 | 4.55 |
| 404.40 | 5.09 | 5.09 |
| 459.62 | 5.16 | 5.16 |
| 457.32 | 3.51 | 3.51 |
| 365.46 | 4.12 | 4.12 |
| 436.90 | 4.15 | 4.15 |
| 267.24 | 3.33 | 3.33 |
| 340.40 | 3.59 | 3.59 |
| 407.43 | 4.23 | 4.23 |
| 421.46 | 4.54 | 4.54 |
| 484.51 | 6.25 | 6.25 |
| 381.46 | 3.90 | 3.90 |
| 348.45 | 4.92 | 4.92 |
| 442.57 | 4.13 | 4.13 |
| 386.41 | 4.95 | 4.95 |
| 407.81 | 3.93 | 3.93 |
| 442.56 | 3.24 | 3.24 |
| 427.51 | 2.66 | 2.66 |
| 455.97 | 4.89 | 4.89 |
| 236.66 | 2.26 | 2.26 |
| 442.97 | 2.36 | 2.36 |
| 282.76 | 2.12 | 2.12 |
| 251.70 | 3.12 | 3.12 |
| 210.19 | 1.99 | 1.99 |
| 482.52 | 5.30 | 5.30 |
| 376.36 | 1.32 | 1.32 |
| 357.44 | 3.11 | 3.11 |
| 410.47 | 2.12 | 2.12 |
| 441.53 | 2.75 | 2.75 |
| 443.46 | 4.52 | 4.52 |
| 437.52 | 3.93 | 3.93 |
| 286.36 | 1.17 | 1.17 |
| 319.84 | 2.34 | 2.34 |
| 395.53 | 3.56 | 3.56 |
| 290.28 | 0.44 | 0.44 |
| 516.58 | 4.48 | 4.48 |
| 390.42 | 4.10 | 4.10 |
| 382.42 | 5.44 | 5.44 |
| 458.95 | 3.93 | 3.93 |
| 225.32 | 1.73 | 1.73 |
| 378.39 | 3.65 | 3.65 |
| 336.34 | 1.57 | 1.57 |
| 449.46 | 3.61 | 3.61 |
| 316.31 | 2.25 | 2.25 |
| 344.37 | 3.74 | 3.74 |
| 340.39 | 3.94 | 3.94 |
| 401.45 | 4.05 | 4.05 |
| 523.60 | 3.33 | 3.33 |
| 456.55 | 3.80 | 3.80 |
| 506.49 | 4.36 | 4.36 |
| 431.45 | 4.13 | 4.13 |
| 392.33 | 3.45 | 3.45 |
| 267.67 | 1.79 | 1.79 |
| 374.35 | 4.51 | 4.51 |
| 417.45 | 3.75 | 3.75 |
| 283.40 | 3.77 | 3.77 |
| 326.83 | 5.38 | 5.38 |
| 350.85 | 4.90 | 4.90 |
| 430.46 | 1.89 | 1.89 |
| 497.57 | 3.95 | 3.95 |
| 381.44 | 4.31 | 4.31 |
| 290.32 | 1.05 | 1.05 |
| 417.43 | 2.41 | 2.41 |
| 341.82 | 2.36 | 2.36 |
| 410.74 | 4.54 | 4.54 |
| 428.47 | 2.30 | 2.30 |
| 493.54 | 3.78 | 3.78 |
| 372.45 | 4.17 | 4.17 |
| 438.51 | 2.90 | 2.90 |
| 329.81 | 4.06 | 4.06 |
| 404.49 | 4.67 | 4.67 |
| 370.82 | 0.75 | 0.75 |
| 523.55 | 3.61 | 3.61 |
| 490.92 | 3.80 | 3.80 |
| 320.40 | 2.61 | 2.61 |
| 469.57 | 6.27 | 6.27 |
| 422.53 | 4.77 | 4.77 |
| 249.38 | 3.23 | 3.23 |
| 419.41 | 3.12 | 3.12 |
| 221.24 | 2.27 | 2.27 |
| 258.71 | 3.05 | 3.05 |
| 278.31 | 2.56 | 2.56 |
| 452.54 | 3.74 | 3.74 |
| 407.81 | 3.93 | 3.93 |
| 406.31 | 3.78 | 3.78 |
| 328.35 | 0.00 | 0.00 |
| 319.67 | 2.09 | 2.09 |
| 404.40 | 5.09 | 5.09 |
| 383.50 | 3.98 | 3.98 |
| 327.34 | 1.64 | 1.64 |
| 444.45 | 3.02 | 3.02 |
| 328.35 | 0.00 | 0.00 |
| 451.51 | 2.72 | 2.72 |
| 426.52 | 1.84 | 1.84 |
| 222.26 | 3.03 | 3.03 |
| 401.35 | 4.22 | 4.22 |
| 261.37 | 0.19 | 0.19 |
| 399.41 | 2.23 | 2.23 |
| 223.23 | 1.27 | 1.27 |
| 472.54 | 3.63 | 3.63 |
| 352.80 | 1.71 | 1.71 |
| 332.34 | 1.97 | 1.97 |
| 406.80 | 4.20 | 4.20 |
| 433.58 | 5.20 | 5.20 |
| 373.35 | 2.33 | 2.33 |
| 449.54 | 3.59 | 3.59 |
| 452.28 | 5.93 | 5.93 |
| 408.40 | 1.79 | 1.79 |
| 462.51 | 2.47 | 2.47 |
| 463.58 | 2.59 | 2.59 |
| 438.53 | 4.85 | 4.85 |
| 226.28 | 3.39 | 3.39 |
| 381.53 | 4.53 | 4.53 |
| 317.33 | 0.82 | 0.82 |
| 280.41 | 2.78 | 2.78 |
| 249.25 | 0.15 | 0.15 |
| 305.40 | 2.13 | 2.13 |
| 380.38 | 4.06 | 4.06 |
| 393.90 | 5.61 | 5.61 |
| 364.36 | 3.57 | 3.57 |
| 288.69 | 3.48 | 3.48 |
| 352.42 | 3.25 | 3.25 |
| 241.20 | 2.54 | 2.54 |
| 486.60 | 4.87 | 4.87 |
| 410.47 | 1.95 | 1.95 |
| 319.77 | 1.70 | 1.70 |
| 372.38 | 2.53 | 2.53 |
| 393.40 | 2.93 | 2.93 |
| 404.84 | 1.59 | 1.59 |
| 416.48 | 4.53 | 4.53 |
| 326.25 | 5.03 | 5.03 |
| 336.35 | 2.04 | 2.04 |
| 250.21 | 1.26 | 1.26 |
| 456.55 | 4.01 | 4.01 |
| 380.44 | 3.93 | 3.93 |
| 388.54 | 2.55 | 2.55 |
| 320.37 | 1.57 | 1.57 |
| 410.54 | 3.12 | 3.12 |
| 343.46 | 2.35 | 2.35 |
| 335.36 | 3.31 | 3.31 |
| 459.55 | 4.42 | 4.42 |
| 327.34 | 1.83 | 1.83 |
| 472.50 | 4.92 | 4.92 |
| 441.47 | 4.95 | 4.95 |
| 416.46 | 2.41 | 2.41 |
| 364.41 | 3.61 | 3.61 |
| 441.47 | 4.95 | 4.95 |
| 362.43 | 4.75 | 4.75 |
| 444.99 | 2.23 | 2.23 |
| 404.40 | 5.09 | 5.09 |
| 346.36 | 1.06 | 1.06 |
| 456.52 | 1.59 | 1.59 |
| 364.47 | 0.91 | 0.91 |
| 422.53 | 2.15 | 2.15 |
| 383.42 | 4.18 | 4.18 |
| 401.26 | 2.93 | 2.93 |
| 469.59 | 5.01 | 5.01 |
| 285.31 | 1.02 | 1.02 |
| 285.34 | 2.97 | 2.97 |
| 235.36 | 2.84 | 2.84 |
| 391.50 | 3.91 | 3.91 |
| 361.85 | 3.68 | 3.68 |
| 377.47 | 1.88 | 1.88 |
| 363.33 | 2.77 | 2.77 |
| 301.37 | 1.75 | 1.75 |
| 392.41 | 2.54 | 2.54 |
| 324.34 | 2.79 | 2.79 |
| 372.22 | 1.59 | 1.59 |
| 361.70 | 2.26 | 2.26 |
| 264.28 | 2.47 | 2.47 |
| 331.37 | 2.85 | 2.85 |
| 260.32 | 3.13 | 3.13 |
| 422.49 | 2.28 | 2.28 |
| 401.49 | 2.45 | 2.45 |
| 373.35 | 2.33 | 2.33 |
| 373.21 | 2.32 | 2.32 |
| 507.59 | 4.05 | 4.05 |
| 440.44 | 3.58 | 3.58 |
| 364.19 | 3.30 | 3.30 |
| 507.49 | 8.30 | 8.30 |
| 361.36 | 2.84 | 2.84 |
| 373.41 | 4.15 | 4.15 |
| 378.84 | 3.60 | 3.60 |
| 426.52 | 2.73 | 2.73 |
| 437.52 | 3.93 | 3.93 |
| 490.61 | 5.11 | 5.11 |
| 245.23 | 1.29 | 1.29 |
| 420.47 | 5.35 | 5.35 |
| 220.23 | 1.50 | 1.50 |
| 458.49 | 2.51 | 2.51 |
| 328.30 | 2.12 | 2.12 |
| 370.70 | 5.14 | 5.14 |
| 394.45 | 4.02 | 4.02 |
| 376.45 | 5.14 | 5.14 |
| 331.80 | 3.70 | 3.70 |
| 231.25 | 1.93 | 1.93 |
| 460.88 | 2.43 | 2.43 |
| 312.28 | 2.97 | 2.97 |
| 245.28 | 2.23 | 2.23 |
| 371.41 | 4.36 | 4.36 |
| 284.36 | 1.04 | 1.04 |
| 256.22 | ||
| 464.52 | 5.15 | 5.15 |
| 438.42 | 1.05 | 1.05 |
| 258.71 | 3.05 | 3.05 |
| 352.39 | 3.52 | 3.52 |
| 237.25 | 1.36 | 1.36 |
| 390.44 | 5.34 | 5.34 |
| 298.73 | 3.12 | 3.12 |
| 410.43 | 3.81 | 3.81 |
| 354.39 | 2.32 | 2.32 |
| 432.57 | 3.71 | 3.71 |
| 320.37 | 2.45 | 2.45 |
| 375.41 | 1.61 | 1.61 |
| 542.59 | 3.91 | 3.91 |
| 313.34 | 1.16 | 1.16 |
| 244.08 | 2.02 | 2.02 |
| 343.38 | 3.16 | 3.16 |
| 458.54 | 5.96 | 5.96 |
| 338.32 | 2.91 | 2.91 |
| 351.41 | 4.37 | 4.37 |
| 417.49 | 5.11 | 5.11 |
| 320.35 | 4.10 | 4.10 |
| 293.28 | 2.93 | 2.93 |
| 434.54 | 2.31 | 2.31 |
| 348.38 | 2.06 | 2.06 |
| 367.50 | 4.28 | 4.28 |
| 195.22 | 2.34 | 2.34 |
| 300.34 | 1.76 | 1.76 |
| 395.44 | 2.49 | 2.49 |
| 379.39 | 3.06 | 3.06 |
| 421.45 | 3.25 | 3.25 |
| 312.76 | 3.43 | 3.43 |
| 251.29 | 1.24 | 1.24 |
| 294.31 | 3.54 | 3.54 |
| 317.34 | 4.13 | 4.13 |
| 285.73 | 3.04 | 3.04 |
| 399.45 | 4.90 | 4.90 |
| 341.22 | 2.21 | 2.21 |
| 177.16 | 1.35 | 1.35 |
| 410.38 | 3.71 | 3.71 |
| 385.42 | 4.59 | 4.59 |
| 256.30 | 2.11 | 2.11 |
| 285.39 | 1.69 | 1.69 |
| 488.54 | 3.03 | 3.03 |
| 407.34 | 3.40 | 3.40 |
| 473.58 | 2.58 | 2.58 |
| 362.48 | 2.70 | 2.70 |
| 344.42 | 3.20 | 3.20 |
| 226.23 | 3.11 | 3.11 |
| 326.31 | 3.27 | 3.27 |
| 355.36 | 4.02 | 4.02 |
| 497.55 | 2.73 | 2.73 |
| 582.48 | 2.89 | 2.89 |
| 337.75 | 2.84 | 2.84 |
| 214.18 | 1.79 | 1.79 |
| 448.52 | 2.84 | 2.84 |
| 279.32 | 3.70 | 3.70 |
| 282.73 | 4.16 | 4.16 |
| 382.42 | 1.03 | 1.03 |
| 409.42 | 2.97 | 2.97 |
| 298.35 | 1.74 | 1.74 |
| 363.40 | 1.06 | 1.06 |
| 372.24 | 2.52 | 2.52 |
| 415.45 | 3.84 | 3.84 |
| 408.45 | 3.93 | 3.93 |
| 463.54 | 1.19 | 1.19 |
| 442.97 | 2.36 | 2.36 |
| 439.91 | 4.71 | 4.71 |
| 407.50 | 3.92 | 3.92 |
| 362.30 | 3.44 | 3.44 |
| 358.19 | 4.12 | 4.12 |
| 426.89 | 3.03 | 3.03 |
| 402.20 | 3.73 | 3.73 |
| 336.39 | 3.59 | 3.59 |
| 278.38 | 3.37 | 3.37 |
| 197.24 | 2.82 | 2.82 |
| 274.33 | 3.46 | 3.46 |
| 415.51 | 3.67 | 3.67 |
| 366.38 | 3.50 | 3.50 |
| 478.46 | 6.02 | 6.02 |
| 334.40 | 4.38 | 4.38 |
| 248.11 | 1.64 | 1.64 |
| 354.39 | 3.69 | 3.69 |
| 406.80 | 4.20 | 4.20 |
| 512.97 | 2.92 | 2.92 |
| 316.41 | 4.84 | 4.84 |
| 506.97 | 5.43 | 5.43 |
| 359.36 | 4.40 | 4.40 |
| 359.36 | 4.40 | 4.40 |
| 307.63 | 3.85 | 3.85 |
| 242.76 | 3.40 | 3.40 |
| 332.36 | 3.67 | 3.67 |
| 340.39 | 2.14 | 2.14 |
| 257.77 | 3.10 | 3.10 |
| 198.18 | -0.53 | -0.53 |
| 274.35 | 3.09 | 3.09 |
| 378.82 | 3.75 | 3.75 |
| 434.41 | 3.08 | 3.08 |
| 300.79 | 3.27 | 3.27 |
| 433.42 | 4.07 | 4.07 |
| 571.66 | 5.88 | 5.88 |
| 372.38 | 4.28 | 4.28 |
| 530.61 | 5.49 | 5.49 |
| 359.39 | 3.51 | 3.51 |
| 397.43 | 5.23 | 5.23 |
| 349.31 | 2.75 | 2.75 |
| 427.40 | 3.48 | 3.48 |
| 258.28 | 2.13 | 2.13 |
| 334.34 | 2.44 | 2.44 |
| 255.28 | 2.49 | 2.49 |
| 392.42 | 3.30 | 3.30 |
| 348.37 | 3.60 | 3.60 |
| 312.30 | 2.69 | 2.69 |
| 397.34 | 2.24 | 2.24 |
| 524.62 | 2.98 | 2.98 |
| 277.20 | 4.05 | 4.05 |
| 253.74 | 2.96 | 2.96 |
| 379.33 | 2.48 | 2.48 |
| 365.43 | 2.80 | 2.80 |
| 288.78 | 3.11 | 3.11 |
| 355.83 | 5.02 | 5.02 |
| 427.44 | 1.90 | 1.90 |
| 364.34 | 1.42 | 1.42 |
| 531.52 | 4.40 | 4.40 |
| 385.25 | 4.36 | 4.36 |
| 324.29 | 1.97 | 1.97 |
| 359.39 | 4.66 | 4.66 |
| 413.38 | 3.17 | 3.17 |