Assay Report Card

Basic Information

ID: ALA1614195

Type: Functional

Description: PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1476 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent))]

Organism: Trypanosoma cruzi

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
302.241.991.99
392.441.621.62
275.352.622.62
482.442.362.36
396.454.554.55
406.916.616.61
182.233.023.02
312.430.330.33
422.352.452.45
253.270.830.83
506.607.017.01
268.291.751.75
246.314.494.49
502.777.287.28
320.435.175.17
94.120.660.66
382.462.862.86
364.495.885.88
356.065.865.86
505.464.184.18
516.555.405.40
438.576.986.98
274.18
208.222.732.73
223.232.312.31
518.566.386.38
337.46-0.77-0.77
336.393.143.14
493.624.594.59
256.211.581.58
582.068.098.09
296.553.623.62
351.862.692.69
331.803.333.33
314.380.530.53
318.241.691.69
383.531.941.94
262.274.154.15
192.171.511.51
610.676.326.32
220.251.291.29
518.496.256.25
454.393.163.16
233.752.372.37
307.353.303.30
213.19-0.24-0.24
652.718.158.15
456.686.176.17
398.506.386.38
200.242.242.24
321.760.830.83
324.773.193.19
458.473.963.96
427.376.346.34
182.223.213.21
243.292.362.36
219.294.584.58
357.41-1.25-1.25
428.346.856.85
289.393.303.30
516.552.332.33
204.622.162.16
512.755.635.63
327.123.863.86
367.382.122.12
379.421.991.99
351.321.651.65
288.403.903.90
350.235.065.06
302.241.991.99
310.401.731.73
383.382.882.88
774.921.191.19
447.924.064.06
512.616.086.08
903.099.239.23
486.575.575.57
518.656.466.46
175.191.681.68
404.82
186.211.341.34
301.524.154.15
218.291.331.33
318.373.583.58
287.311.931.93
316.353.003.00
320.383.503.50
579.990.000.00
340.28-1.32-1.32
296.414.014.01
254.172.402.40
316.792.782.78
346.822.792.79
383.501.561.56
372.863.673.67
307.403.133.13
486.581.741.74
459.553.353.35
344.834.274.27
307.183.613.61
422.445.335.33
457.994.144.14
457.994.144.14
457.994.094.09
367.925.325.32
289.320.590.59
191.251.961.96
306.321.891.89
288.312.802.80
233.281.131.13
473.554.544.54
360.645.105.10
360.645.105.10
360.645.105.10
345.832.902.90
340.393.943.94
207.19-1.32-1.32
386.883.973.97
193.17-1.63-1.63
325.423.023.02
444.545.865.86
430.334.574.57
359.404.984.98
331.465.325.32
281.313.073.07
681.786.946.94
336.354.034.03
549.895.235.23
397.392.102.10
462.933.203.20
387.482.972.97
391.423.073.07
389.792.272.27
490.875.015.01
372.421.911.91
462.933.203.20
374.243.063.06
317.710.610.61
672.963.953.95
973.679.009.00
687.7110.2910.29
369.253.123.12
592.124.264.26
369.311.581.58
423.935.145.14
374.652.562.56
205.291.521.52
205.220.940.94
390.464.354.35
440.464.814.81
401.663.343.34
412.494.434.43
378.361.301.30
278.402.832.83
384.391.641.64
449.533.773.77
326.382.772.77
273.303.813.81
278.271.071.07
392.414.854.85
444.463.553.55
417.244.524.52
258.713.053.05
431.515.355.35
402.285.665.66
359.434.564.56
421.412.972.97
368.433.023.02
414.773.273.27
377.421.201.20
362.524.504.50
454.872.952.95
486.642.832.83
286.333.993.99
431.401.831.83
395.403.133.13
506.614.454.45
486.373.653.65
357.454.614.61
360.373.653.65
407.542.392.39
404.812.022.02
231.282.872.87
319.332.912.91
489.305.835.83
511.455.255.25
292.294.164.16
401.492.552.55
443.623.673.67
297.332.682.68
427.753.983.98
363.351.521.52
298.414.184.18
321.424.844.84
484.974.894.89
482.562.592.59
337.363.483.48
353.432.492.49
383.865.095.09
400.444.494.49
309.372.932.93
343.403.893.89
329.413.613.61
447.933.063.06
952.52-1.36-1.36
294.312.892.89
415.493.103.10
285.373.543.54
264.283.113.11
375.473.533.53
358.402.382.38
415.503.023.02
477.905.335.33
463.324.214.21
422.854.704.70
423.332.112.11
373.414.824.82
307.783.453.45
497.585.805.80
476.555.025.02
220.261.211.21
510.545.525.52
296.424.344.34
402.502.892.89
539.346.056.05
432.903.193.19
429.503.923.92
298.373.873.87
375.783.463.46
395.461.761.76
335.404.614.61
469.522.942.94
862.75-1.10-1.10
357.843.573.57
766.597.737.73
503.914.014.01
432.481.881.88
405.544.664.66
305.393.223.22
425.965.015.01
361.411.011.01
310.363.283.28
349.484.364.36
463.975.315.31
380.443.183.18
401.571.501.50
434.525.105.10
390.874.874.87
339.413.953.95
492.603.873.87
335.834.094.09
405.544.664.66
325.423.393.39
373.864.344.34
405.451.521.52
435.502.712.71
451.574.394.39
252.282.352.35
309.793.563.56
339.324.124.12
465.743.703.70
474.542.562.56
456.504.614.61
326.404.494.49
327.172.002.00
304.423.673.67
297.333.853.85
196.211.091.09
303.324.084.08
499.494.344.34
309.414.554.55
275.181.841.84
480.373.903.90
345.453.233.23
473.623.673.67
495.655.855.85
276.30-0.58-0.58
276.241.951.95
361.354.924.92
458.493.343.34
295.342.542.54
335.833.873.87
303.363.403.40
309.363.443.44
331.402.072.07
479.572.042.04
1056.402.752.75
323.304.684.68
321.364.204.20
249.273.033.03
442.573.503.50
419.574.974.97
329.792.252.25
378.464.134.13
261.363.833.83
317.352.252.25
220.222.122.12
546.496.386.38
373.883.133.13
352.422.552.55
459.625.165.16
339.402.542.54
381.441.391.39
345.384.684.68
301.354.294.29
365.393.663.66
328.280.810.81
380.353.703.70
363.373.443.44
282.303.483.48
419.574.974.97
391.335.085.08
248.383.563.56
457.493.743.74
486.595.065.06
442.524.424.42
361.493.963.96
387.441.191.19
444.535.435.43
244.300.940.94
368.420.440.44
432.394.804.80
247.250.930.93
423.495.525.52
430.583.853.85
322.322.392.39
365.464.124.12
516.555.405.40
308.361.991.99
339.263.493.49
324.423.923.92
426.592.732.73
416.492.412.41
176.171.961.96
600.6111.1711.17
351.363.293.29
287.814.364.36
265.312.452.45
352.391.701.70
381.844.184.18
328.393.363.36
385.494.464.46
434.411.511.51
220.281.381.38
438.946.206.20
599.664.754.75
396.362.632.63
426.565.265.26
289.353.813.81
303.710.690.69
387.944.694.69
452.542.662.66
359.473.723.72
349.352.872.87
321.383.763.76
327.172.002.00
385.533.063.06
287.322.402.40
463.510.360.36
341.413.713.71
373.883.523.52
509.573.593.59
304.742.242.24
394.392.932.93
381.441.391.39
396.492.752.75
360.374.434.43
329.364.954.95
316.743.713.71
236.271.171.17
373.485.275.27
399.454.494.49
327.341.851.85
547.373.973.97
515.574.444.44
325.371.381.38
359.825.855.85
258.713.363.36
403.915.025.02
480.506.056.05
317.353.293.29
421.884.554.55
228.172.562.56
432.322.522.52
242.303.253.25
251.242.832.83
270.122.982.98
379.404.764.76
455.354.614.61
437.564.274.27
320.403.103.10
271.343.203.20
350.381.201.20
278.314.344.34
425.491.381.38
306.773.433.43
491.342.072.07
205.242.322.32
426.484.604.60
465.333.783.78
239.282.822.82
328.332.182.18
366.764.354.35
309.371.781.78
449.984.724.72
423.543.963.96
375.422.242.24
380.411.091.09
328.332.182.18
381.463.903.90
298.432.252.25
461.543.533.53
382.512.882.88
442.574.134.13
391.421.971.97
270.670.100.10
267.333.803.80
353.350.720.72
388.351.511.51
517.484.754.75
486.591.781.78
350.383.143.14
290.373.403.40
419.282.982.98
385.491.891.89
371.444.514.51
325.371.381.38
365.503.363.36
736.32-0.46-0.46
385.493.023.02
508.865.155.15
396.414.474.47
430.562.902.90
341.372.682.68
445.483.683.68
471.513.353.35
267.723.943.94
331.812.512.51
309.372.612.61
549.504.534.53
349.364.244.24
283.312.672.67
314.393.983.98
224.272.662.66
494.584.194.19
275.382.962.96
434.524.134.13
399.174.124.12
361.404.684.68
150.89-2.94-2.94
552.992.642.64
321.803.703.70
326.364.294.29
316.371.441.44
424.354.864.86
453.542.162.16
326.441.781.78
298.313.683.68
248.231.821.82
471.842.322.32
332.394.544.54
370.574.564.56
335.203.893.89
416.532.742.74
420.943.433.43
368.443.303.30
379.420.910.91
410.813.663.66
224.263.493.49
291.764.084.08
278.313.793.79
360.423.553.55
312.331.151.15
246.293.093.09
323.833.953.95
342.214.204.20
380.433.743.74
381.505.595.59
369.233.133.13
443.895.495.49
312.352.612.61
406.944.004.00
312.372.702.70
358.422.742.74
330.773.983.98
375.492.442.44
278.313.293.29
397.234.314.31
258.323.423.42
448.554.344.34
330.364.984.98
294.354.824.82
400.451.391.39
296.373.553.55
281.363.353.35
415.495.755.75
473.613.433.43
257.292.252.25
373.464.724.72
314.363.223.22
439.323.353.35
319.281.171.17
324.344.194.19
357.361.861.86
381.892.772.77
443.794.114.11
493.364.084.08
297.833.483.48
437.184.754.75
384.443.123.12
376.513.203.20
306.374.434.43
257.683.143.14
456.495.535.53
387.443.333.33
357.844.114.11
381.394.364.36
319.842.342.34
380.434.384.38
325.764.624.62
307.744.464.46
438.364.144.14
840.123.853.85
423.543.963.96
362.455.055.05
426.564.294.29
407.492.952.95
496.984.804.80
308.393.773.77
366.423.503.50
492.024.424.42
306.323.403.40
321.803.753.75
451.434.284.28
424.835.815.81
904.896.076.07
368.802.972.97
456.503.693.69
444.474.134.13
319.322.602.60
446.312.552.55
453.525.005.00
313.392.682.68
401.473.783.78
402.285.665.66
515.694.554.55
299.724.074.07
322.341.111.11
523.384.734.73
246.263.003.00
274.33-0.22-0.22
367.794.084.08
323.402.922.92
426.565.265.26
359.382.052.05
341.192.302.30
292.344.214.21
393.353.393.39
541.564.104.10
352.392.432.43
478.553.923.92
389.914.214.21
395.463.943.94
240.212.642.64
369.835.345.34
828.972.062.06
393.443.693.69
450.613.113.11
317.433.923.92
435.715.605.60
342.423.743.74
298.300.940.94
450.505.115.11
491.603.573.57
280.373.473.47
371.464.804.80
472.663.313.31
385.465.745.74
496.525.135.13
381.433.373.37
433.303.163.16
796.58-0.96-0.96
491.575.085.08
378.393.653.65
476.555.025.02
315.351.381.38
510.513.033.03
429.875.275.27
454.434.214.21
294.313.323.32
328.323.373.37
300.364.714.71
336.822.602.60
382.443.583.58
337.854.344.34
256.242.482.48
347.814.914.91
424.242.922.92
333.311.481.48
359.393.103.10
462.401.581.58
245.352.572.57
387.913.743.74
350.494.364.36
274.393.043.04
450.473.803.80
464.864.454.45
377.081.871.87
265.313.923.92
416.893.493.49
264.282.732.73
422.605.435.43
470.322.632.63
466.504.904.90
399.523.413.41
159.191.401.40
353.453.233.23
426.473.323.32
415.364.824.82
271.303.483.48
314.182.172.17
336.404.054.05
318.433.913.91
394.864.204.20
445.532.402.40
392.452.232.23
310.401.411.41
304.372.212.21
373.413.583.58
431.454.134.13
352.355.015.01
351.454.814.81
318.433.913.91
344.335.525.52
330.374.394.39
482.584.664.66
421.525.085.08
459.735.345.34
447.634.284.28
383.433.573.57
456.533.773.77
392.444.434.43
318.433.633.63
339.853.383.38
429.782.972.97
389.523.813.81
195.222.402.40
372.493.823.82
411.391.851.85
284.363.293.29
288.353.663.66
325.372.312.31
279.273.603.60
385.824.284.28
414.440.800.80
430.462.362.36
407.433.983.98
546.675.725.72
293.322.922.92
282.330.490.49
413.894.304.30
430.471.481.48
497.573.953.95
443.512.552.55
348.453.963.96
361.403.793.79
317.822.582.58
275.341.911.91
508.003.393.39
309.372.552.55
434.734.314.31
429.432.442.44
346.272.072.07
590.37-0.39-0.39
490.553.603.60
393.463.423.42
395.461.931.93
381.505.655.65
405.461.121.12
292.361.581.58
376.422.172.17
315.332.782.78
572.853.543.54
448.554.474.47
403.894.204.20
345.402.672.67
520.085.255.25
522.425.005.00
413.544.054.05
454.015.715.71
358.395.695.69
450.974.004.00
391.842.192.19
424.364.804.80
399.563.463.46
297.363.603.60
308.414.684.68
294.384.124.12
301.341.821.82
350.852.852.85
287.272.772.77
456.554.914.91
450.545.135.13
395.575.165.16
246.310.600.60
485.453.473.47
363.842.232.23
451.553.863.86
464.014.014.01
315.252.702.70
447.472.382.38
418.953.613.61
367.411.081.08
335.284.694.69
333.343.433.43
409.874.524.52
454.472.642.64
341.201.521.52
289.362.892.89
489.593.733.73
406.423.773.77
431.503.873.87
402.462.342.34
375.524.354.35
472.374.704.70
342.402.362.36
406.514.704.70
355.312.352.35
404.423.833.83
323.423.653.65
418.474.014.01
280.332.732.73
411.483.183.18
350.424.454.45
320.424.064.06
286.262.882.88
300.411.151.15
348.863.443.44
365.503.363.36
278.312.612.61
316.792.382.38
436.515.305.30
459.314.744.74
423.493.443.44
334.762.922.92
388.414.334.33
424.462.022.02
347.422.052.05
462.305.255.25
413.593.763.76
374.443.773.77
393.403.193.19
287.703.403.40
395.442.752.75
364.793.773.77
313.403.363.36
345.382.532.53
282.330.120.12
394.454.694.69
405.503.223.22
275.760.590.59
494.552.952.95
274.330.570.57
371.484.174.17
473.915.695.69
546.456.516.51
462.601.911.91
464.574.864.86
389.284.494.49
521.621.931.93
402.462.342.34
290.350.990.99
439.522.482.48
310.395.365.36
240.312.762.76
376.841.881.88
474.472.392.39
292.30-0.45-0.45
473.554.604.60
311.363.173.17
270.342.902.90
509.024.434.43
359.473.383.38
527.604.784.78
363.461.801.80
401.472.432.43
291.381.531.53
366.494.064.06
510.545.525.52
355.463.463.46
512.525.045.04
377.811.881.88
526.463.793.79
424.412.752.75
359.682.722.72
251.242.832.83
385.861.811.81
412.544.144.14
207.662.902.90
257.323.023.02
493.364.084.08
350.945.455.45
451.574.064.06
351.444.244.24
373.504.114.11
295.342.542.54
395.461.761.76
457.525.025.02
287.322.672.67
352.35-0.27-0.27
393.905.615.61
415.453.423.42
369.493.813.81
401.472.682.68
374.402.352.35
493.035.405.40
286.403.953.95
345.782.942.94
476.654.674.67
459.535.395.39
364.411.511.51
380.422.852.85
307.783.313.31
258.713.053.05
456.355.665.66
495.434.764.76
209.251.771.77
239.282.782.78
432.905.395.39
344.763.103.10
399.235.155.15
444.543.543.54
294.813.393.39
994.60-0.34-0.34
388.401.071.07
298.393.683.68
276.291.951.95
301.354.254.25
375.813.023.02
360.823.423.42
275.352.902.90
450.203.323.32
359.452.952.95
436.456.006.00
308.373.133.13
322.330.610.61
345.371.291.29
373.464.684.68
347.402.402.40
217.221.911.91
368.503.643.64
436.295.675.67
362.402.112.11
461.593.033.03
342.483.343.34
269.302.792.79
506.015.395.39
354.375.495.49
323.433.083.08
305.293.743.74
297.362.892.89
398.474.134.13
359.853.093.09
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