Basic Information
ID: ALA1614199
Type: Binding
Description: PUBCHEM_BIOASSAY: Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 629 (Primary screen preceding this dose response confirmation assay.)]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614199
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 3.57 | 3.57 |
| 406.91 | 6.61 | 6.61 |
| 308.38 | 3.79 | 3.79 |
| 356.06 | 5.86 | 5.86 |
| 368.52 | 5.11 | 5.11 |
| 518.56 | 6.38 | 6.38 |
| 142.11 | 0.40 | 0.40 |
| 309.20 | 3.25 | 3.25 |
| 317.35 | 3.11 | 3.11 |
| 228.29 | 3.37 | 3.37 |
| 139.13 | 0.92 | 0.92 |
| 239.23 | 3.19 | 3.19 |
| 423.43 | 2.73 | 2.73 |
| 289.32 | 2.73 | 2.73 |
| 382.40 | 2.93 | 2.93 |
| 246.26 | 3.17 | 3.17 |
| 287.77 | 4.60 | 4.60 |
| 285.33 | 3.36 | 3.36 |
| 285.31 | 3.94 | 3.94 |
| 365.36 | 1.77 | 1.77 |
| 390.46 | 4.35 | 4.35 |
| 321.38 | 3.60 | 3.60 |
| 220.22 | 2.97 | 2.97 |
| 449.53 | 3.77 | 3.77 |
| 278.27 | 1.07 | 1.07 |
| 307.44 | 3.83 | 3.83 |
| 432.48 | 2.04 | 2.04 |
| 443.53 | 5.18 | 5.18 |
| 432.53 | 2.92 | 2.92 |
| 424.39 | 3.05 | 3.05 |
| 366.81 | 3.71 | 3.71 |
| 433.60 | 3.56 | 3.56 |
| 395.47 | 4.20 | 4.20 |
| 302.33 | 1.46 | 1.46 |
| 250.37 | 1.87 | 1.87 |
| 392.41 | 2.70 | 2.70 |
| 319.38 | 2.91 | 2.91 |
| 388.45 | 4.16 | 4.16 |
| 444.47 | 3.08 | 3.08 |
| 441.51 | 3.06 | 3.06 |
| 334.47 | 3.82 | 3.82 |
| 455.44 | 4.97 | 4.97 |
| 389.80 | 2.35 | 2.35 |
| 299.36 | 3.13 | 3.13 |
| 467.48 | 2.08 | 2.08 |
| 329.41 | 3.29 | 3.29 |
| 428.58 | 4.21 | 4.21 |
| 459.46 | 2.41 | 2.41 |
| 473.48 | 3.54 | 3.54 |
| 463.49 | 3.79 | 3.79 |
| 404.46 | 4.17 | 4.17 |
| 379.46 | 2.00 | 2.00 |
| 381.43 | 3.78 | 3.78 |
| 424.49 | 4.01 | 4.01 |
| 296.33 | 2.36 | 2.36 |
| 313.35 | 3.56 | 3.56 |
| 425.87 | 4.18 | 4.18 |
| 398.42 | 4.36 | 4.36 |
| 380.41 | 4.02 | 4.02 |
| 348.31 | 3.52 | 3.52 |
| 242.24 | 0.09 | 0.09 |
| 430.58 | 3.85 | 3.85 |
| 365.46 | 4.12 | 4.12 |
| 379.80 | 4.56 | 4.56 |
| 496.49 | 5.38 | 5.38 |
| 452.49 | 4.26 | 4.26 |
| 457.56 | 4.61 | 4.61 |
| 327.77 | 3.63 | 3.63 |
| 337.43 | 5.24 | 5.24 |
| 490.54 | 5.25 | 5.25 |
| 444.33 | 4.13 | 4.13 |
| 354.41 | 2.53 | 2.53 |
| 495.61 | 4.28 | 4.28 |
| 476.58 | 2.32 | 2.32 |
| 349.35 | 2.87 | 2.87 |
| 274.30 | 2.93 | 2.93 |
| 468.97 | 4.75 | 4.75 |
| 444.53 | 5.75 | 5.75 |
| 450.97 | 3.85 | 3.85 |
| 395.44 | 2.68 | 2.68 |
| 252.27 | 3.41 | 3.41 |
| 364.45 | 5.17 | 5.17 |
| 380.54 | 3.74 | 3.74 |
| 366.49 | 2.60 | 2.60 |
| 343.42 | 4.38 | 4.38 |
| 381.46 | 3.90 | 3.90 |
| 442.57 | 4.13 | 4.13 |
| 306.32 | 3.42 | 3.42 |
| 290.33 | 2.59 | 2.59 |
| 174.22 | -0.05 | -0.05 |
| 472.55 | 4.21 | 4.21 |
| 398.38 | 3.89 | 3.89 |
| 327.46 | 2.35 | 2.35 |
| 350.42 | 2.91 | 2.91 |
| 480.89 | 3.50 | 3.50 |
| 391.45 | 3.66 | 3.66 |
| 317.34 | 2.63 | 2.63 |
| 379.42 | 3.98 | 3.98 |
| 349.41 | 2.52 | 2.52 |
| 318.79 | 3.99 | 3.99 |
| 449.92 | 5.64 | 5.64 |
| 475.49 | 5.25 | 5.25 |
| 324.85 | 3.16 | 3.16 |
| 451.87 | 4.08 | 4.08 |
| 294.31 | 3.13 | 3.13 |
| 266.68 | 2.90 | 2.90 |
| 385.29 | 4.37 | 4.37 |
| 218.28 | 2.32 | 2.32 |
| 341.39 | 3.12 | 3.12 |
| 383.21 | 4.03 | 4.03 |
| 297.83 | 3.45 | 3.45 |
| 223.23 | 0.77 | 0.77 |
| 454.50 | 2.50 | 2.50 |
| 303.31 | 1.91 | 1.91 |
| 380.41 | 4.35 | 4.35 |
| 320.35 | 3.81 | 3.81 |
| 246.31 | 1.94 | 1.94 |
| 467.57 | 4.09 | 4.09 |
| 357.44 | 3.19 | 3.19 |
| 307.40 | 3.08 | 3.08 |
| 404.22 | 1.68 | 1.68 |
| 431.49 | 4.26 | 4.26 |
| 381.43 | 3.59 | 3.59 |
| 469.88 | 4.40 | 4.40 |
| 395.85 | 3.95 | 3.95 |
| 434.57 | 2.92 | 2.92 |
| 342.36 | 2.49 | 2.49 |
| 489.92 | 5.70 | 5.70 |
| 350.33 | 3.26 | 3.26 |
| 410.46 | 3.81 | 3.81 |
| 545.66 | 4.79 | 4.79 |
| 376.46 | 3.02 | 3.02 |
| 376.48 | 3.03 | 3.03 |
| 414.51 | 3.45 | 3.45 |
| 394.50 | 3.36 | 3.36 |
| 337.45 | 2.75 | 2.75 |
| 461.57 | 5.36 | 5.36 |
| 390.40 | 4.01 | 4.01 |
| 342.36 | 4.24 | 4.24 |
| 483.00 | 4.43 | 4.43 |
| 292.34 | 3.61 | 3.61 |
| 412.47 | 3.94 | 3.94 |
| 428.47 | 2.86 | 2.86 |
| 414.49 | 5.11 | 5.11 |
| 318.13 | 3.96 | 3.96 |
| 490.55 | 3.60 | 3.60 |
| 421.50 | 4.89 | 4.89 |
| 348.45 | 4.29 | 4.29 |
| 388.54 | 3.24 | 3.24 |
| 471.26 | 4.76 | 4.76 |
| 393.30 | 5.16 | 5.16 |
| 400.40 | 2.61 | 2.61 |
| 238.25 | 3.08 | 3.08 |
| 408.21 | 4.39 | 4.39 |
| 454.47 | 2.64 | 2.64 |
| 355.45 | 3.15 | 3.15 |
| 339.78 | 5.01 | 5.01 |
| 394.41 | -0.81 | -0.81 |
| 365.48 | 3.31 | 3.31 |
| 297.77 | 2.08 | 2.08 |
| 448.51 | 3.86 | 3.86 |
| 589.77 | 5.72 | 5.72 |
| 402.68 | 6.74 | 6.74 |
| 459.31 | 4.74 | 4.74 |
| 390.49 | 3.23 | 3.23 |
| 486.98 | 3.57 | 3.57 |
| 412.22 | 5.04 | 5.04 |
| 309.33 | 1.31 | 1.31 |
| 332.36 | 4.33 | 4.33 |
| 293.74 | 3.01 | 3.01 |
| 356.47 | 5.06 | 5.06 |
| 352.39 | 3.35 | 3.35 |
| 538.03 | 5.39 | 5.39 |
| 241.31 | 1.54 | 1.54 |
| 427.57 | 2.29 | 2.29 |
| 263.28 | 0.35 | 0.35 |
| 358.45 | 3.22 | 3.22 |
| 287.31 | 3.01 | 3.01 |
| 283.28 | 2.55 | 2.55 |
| 354.32 | 1.90 | 1.90 |
| 347.40 | 2.40 | 2.40 |
| 459.52 | 2.91 | 2.91 |
| 425.83 | 2.96 | 2.96 |
| 354.43 | 4.81 | 4.81 |
| 331.42 | 3.36 | 3.36 |
| 411.44 | 3.74 | 3.74 |
| 337.42 | 2.65 | 2.65 |
| 269.26 | 2.32 | 2.32 |
| 432.30 | 3.45 | 3.45 |
| 386.79 | 2.65 | 2.65 |
| 432.43 | 5.00 | 5.00 |
| 294.31 | 3.53 | 3.53 |
| 405.49 | 3.05 | 3.05 |
| 370.41 | 4.77 | 4.77 |
| 237.11 | 2.88 | 2.88 |
| 258.35 | 3.35 | 3.35 |
| 318.40 | 2.85 | 2.85 |
| 433.58 | 3.13 | 3.13 |
| 357.41 | 4.44 | 4.44 |
| 342.46 | 3.21 | 3.21 |
| 449.54 | 3.59 | 3.59 |
| 437.57 | 3.53 | 3.53 |
| 429.50 | 2.53 | 2.53 |
| 256.30 | 2.98 | 2.98 |
| 331.42 | 3.46 | 3.46 |
| 264.28 | 1.07 | 1.07 |
| 421.41 | 2.18 | 2.18 |
| 424.42 | 2.85 | 2.85 |
| 330.16 | 2.85 | 2.85 |
| 445.34 | 5.07 | 5.07 |
| 396.86 | 5.64 | 5.64 |
| 334.42 | 2.93 | 2.93 |
| 412.54 | 3.49 | 3.49 |
| 296.33 | 2.97 | 2.97 |
| 378.52 | 3.35 | 3.35 |
| 307.35 | 3.61 | 3.61 |
| 321.35 | 2.16 | 2.16 |
| 368.66 | 3.87 | 3.87 |
| 326.38 | 3.33 | 3.33 |
| 514.33 | 4.56 | 4.56 |
| 377.44 | 4.28 | 4.28 |
| 442.97 | 3.84 | 3.84 |
| 434.45 | 2.38 | 2.38 |
| 369.38 | 1.39 | 1.39 |
| 155.20 | 0.73 | 0.73 |
| 451.48 | 3.34 | 3.34 |
| 369.45 | 3.56 | 3.56 |
| 325.37 | 0.88 | 0.88 |
| 239.32 | 2.09 | 2.09 |
| 353.45 | 4.48 | 4.48 |
| 442.57 | 3.55 | 3.55 |
| 312.28 | 2.02 | 2.02 |
| 311.22 | 2.79 | 2.79 |
| 265.36 | 3.02 | 3.02 |
| 395.42 | 3.33 | 3.33 |
| 314.32 | 1.81 | 1.81 |
| 375.38 | 3.01 | 3.01 |
| 304.19 | 3.38 | 3.38 |
| 362.39 | 4.64 | 4.64 |
| 266.30 | 3.07 | 3.07 |
| 417.52 | 4.17 | 4.17 |
| 358.34 | 3.42 | 3.42 |
| 388.47 | 2.83 | 2.83 |
| 366.44 | 3.85 | 3.85 |
| 366.40 | 3.28 | 3.28 |
| 280.71 | 3.21 | 3.21 |
| 437.45 | 2.95 | 2.95 |
| 254.26 | 3.87 | 3.87 |
| 329.45 | 3.44 | 3.44 |
| 289.33 | 1.70 | 1.70 |
| 406.23 | 3.16 | 3.16 |
| 326.74 | 4.16 | 4.16 |
| 297.38 | 3.35 | 3.35 |
| 384.40 | 2.25 | 2.25 |
| 293.31 | 3.03 | 3.03 |
| 463.36 | 3.82 | 3.82 |
| 216.24 | 2.21 | 2.21 |
| 407.46 | 3.46 | 3.46 |
| 427.48 | 2.60 | 2.60 |
| 429.92 | 3.57 | 3.57 |
| 481.42 | 3.83 | 3.83 |
| 311.34 | 2.52 | 2.52 |
| 430.46 | 4.67 | 4.67 |
| 415.28 | 3.77 | 3.77 |
| 349.35 | 3.42 | 3.42 |
| 430.49 | 4.43 | 4.43 |
| 385.42 | 3.79 | 3.79 |
| 443.55 | 4.12 | 4.12 |
| 314.37 | 3.34 | 3.34 |
| 251.28 | 1.84 | 1.84 |
| 459.62 | 3.41 | 3.41 |
| 302.42 | 4.16 | 4.16 |
| 364.43 | 0.99 | 0.99 |
| 481.51 | 3.27 | 3.27 |
| 403.41 | 3.90 | 3.90 |
| 324.34 | 3.99 | 3.99 |
| 321.80 | 3.69 | 3.69 |
| 299.75 | 2.05 | 2.05 |
| 493.96 | 3.69 | 3.69 |
| 455.54 | 3.34 | 3.34 |
| 360.46 | 3.59 | 3.59 |
| 260.39 | 3.78 | 3.78 |
| 385.92 | 3.44 | 3.44 |
| 358.85 | 4.53 | 4.53 |
| 396.50 | 4.28 | 4.28 |
| 271.34 | 2.83 | 2.83 |
| 358.36 | 3.40 | 3.40 |
| 405.47 | 2.54 | 2.54 |
| 375.38 | 4.81 | 4.81 |
| 389.48 | 5.19 | 5.19 |
| 403.49 | 3.30 | 3.30 |
| 436.49 | 3.15 | 3.15 |
| 354.39 | 2.85 | 2.85 |
| 363.44 | 3.73 | 3.73 |
| 464.50 | 3.52 | 3.52 |
| 371.44 | 2.86 | 2.86 |
| 356.43 | 2.81 | 2.81 |
| 294.31 | 4.32 | 4.32 |
| 487.97 | 3.75 | 3.75 |
| 476.58 | 4.35 | 4.35 |
| 427.46 | 3.75 | 3.75 |
| 453.37 | 3.58 | 3.58 |
| 445.48 | 3.05 | 3.05 |
| 381.23 | 1.91 | 1.91 |
| 485.29 | 4.00 | 4.00 |
| 499.64 | 3.63 | 3.63 |
| 413.45 | 3.22 | 3.22 |
| 484.51 | 4.16 | 4.16 |
| 395.37 | 1.61 | 1.61 |
| 285.25 | 2.02 | 2.02 |
| 390.44 | 5.34 | 5.34 |
| 373.46 | 4.09 | 4.09 |
| 464.60 | 2.83 | 2.83 |
| 378.45 | 1.38 | 1.38 |
| 259.33 | 3.51 | 3.51 |
| 349.39 | 4.19 | 4.19 |
| 341.35 | 4.17 | 4.17 |
| 486.35 | 3.39 | 3.39 |
| 387.44 | 4.83 | 4.83 |
| 449.42 | 3.88 | 3.88 |
| 402.49 | 4.78 | 4.78 |
| 314.79 | 2.69 | 2.69 |
| 343.18 | 1.46 | 1.46 |
| 416.87 | 5.45 | 5.45 |
| 353.47 | 3.41 | 3.41 |
| 343.38 | 3.16 | 3.16 |
| 449.53 | 4.63 | 4.63 |
| 353.38 | 3.36 | 3.36 |
| 445.55 | 5.42 | 5.42 |
| 225.25 | 1.09 | 1.09 |
| 392.77 | 3.51 | 3.51 |
| 412.47 | 5.01 | 5.01 |
| 432.25 | 2.23 | 2.23 |
| 381.43 | 4.95 | 4.95 |
| 351.36 | 3.55 | 3.55 |
| 322.20 | 3.90 | 3.90 |
| 358.40 | 4.41 | 4.41 |
| 229.28 | 3.10 | 3.10 |
| 431.56 | 2.78 | 2.78 |
| 356.45 | 2.96 | 2.96 |
| 489.58 | 2.80 | 2.80 |
| 479.59 | 4.99 | 4.99 |
| 478.57 | 4.11 | 4.11 |
| 434.46 | 5.39 | 5.39 |
| 349.42 | 1.54 | 1.54 |
| 285.25 | 2.15 | 2.15 |
| 392.44 | 4.43 | 4.43 |
| 385.45 | 2.35 | 2.35 |
| 392.68 | 4.62 | 4.62 |
| 328.37 | 1.70 | 1.70 |
| 441.90 | 3.73 | 3.73 |
| 333.34 | 1.92 | 1.92 |
| 259.33 | 3.13 | 3.13 |
| 379.51 | 2.66 | 2.66 |
| 349.25 | 3.85 | 3.85 |
| 370.36 | 4.67 | 4.67 |
| 314.82 | 4.21 | 4.21 |
| 417.45 | 3.81 | 3.81 |
| 232.24 | 2.12 | 2.12 |
| 358.36 | 3.38 | 3.38 |
| 399.53 | 2.07 | 2.07 |
| 391.43 | 3.28 | 3.28 |
| 331.46 | 4.21 | 4.21 |
| 434.52 | 4.02 | 4.02 |
| 280.30 | 2.26 | 2.26 |
| 369.40 | 3.92 | 3.92 |
| 359.45 | 2.47 | 2.47 |
| 333.41 | 3.35 | 3.35 |
| 302.32 | 0.63 | 0.63 |
| 314.42 | 3.11 | 3.11 |
| 386.46 | 4.19 | 4.19 |
| 373.43 | 1.88 | 1.88 |
| 404.52 | 4.70 | 4.70 |
| 301.35 | 1.98 | 1.98 |
| 478.53 | 4.00 | 4.00 |
| 320.35 | 4.20 | 4.20 |
| 352.37 | 1.09 | 1.09 |
| 435.30 | 3.20 | 3.20 |
| 304.37 | 3.41 | 3.41 |
| 381.87 | 3.66 | 3.66 |
| 402.44 | 1.69 | 1.69 |
| 301.35 | 3.50 | 3.50 |
| 299.08 | 2.70 | 2.70 |
| 275.35 | 2.22 | 2.22 |
| 277.37 | 3.73 | 3.73 |
| 472.57 | 4.53 | 4.53 |
| 380.54 | 5.74 | 5.74 |
| 353.27 | 4.24 | 4.24 |
| 387.46 | 2.18 | 2.18 |
| 371.90 | 3.40 | 3.40 |
| 398.82 | 2.04 | 2.04 |
| 366.38 | 4.61 | 4.61 |
| 366.45 | 3.67 | 3.67 |
| 394.43 | 4.27 | 4.27 |
| 416.36 | 3.95 | 3.95 |
| 379.27 | 4.77 | 4.77 |
| 299.20 | 2.52 | 2.52 |
| 215.26 | 1.70 | 1.70 |
| 370.43 | 5.96 | 5.96 |
| 271.35 | 3.56 | 3.56 |
| 487.56 | 5.38 | 5.38 |
| 353.18 | 4.11 | 4.11 |
| 339.38 | 2.36 | 2.36 |
| 486.24 | 4.22 | 4.22 |
| 413.52 | 4.39 | 4.39 |
| 383.43 | 2.76 | 2.76 |
| 554.97 | 4.69 | 4.69 |
| 299.31 | 1.86 | 1.86 |
| 415.47 | 3.38 | 3.38 |
| 325.35 | 1.97 | 1.97 |
| 447.52 | 1.74 | 1.74 |
| 331.75 | 4.30 | 4.30 |
| 353.47 | 4.61 | 4.61 |
| 387.91 | 5.27 | 5.27 |
| 330.37 | 3.21 | 3.21 |
| 388.38 | 5.44 | 5.44 |
| 394.46 | 2.49 | 2.49 |
| 335.36 | 4.06 | 4.06 |
| 304.37 | 4.91 | 4.91 |
| 293.67 | 2.55 | 2.55 |
| 373.41 | 3.92 | 3.92 |
| 298.34 | 2.69 | 2.69 |
| 441.24 | 6.19 | 6.19 |
| 310.74 | 4.08 | 4.08 |
| 364.81 | 3.77 | 3.77 |
| 323.80 | 3.00 | 3.00 |
| 394.41 | 1.69 | 1.69 |
| 346.39 | 2.19 | 2.19 |
| 387.45 | 2.83 | 2.83 |
| 365.42 | 4.00 | 4.00 |
| 319.39 | 1.78 | 1.78 |
| 366.35 | 3.81 | 3.81 |
| 379.85 | 4.16 | 4.16 |
| 372.81 | 4.03 | 4.03 |
| 351.84 | 4.81 | 4.81 |
| 430.83 | 3.83 | 3.83 |
| 489.55 | 2.59 | 2.59 |
| 392.22 | 3.54 | 3.54 |
| 384.38 | 2.96 | 2.96 |