PubChem BioAssay. Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactam...

Basic Information

ID: ALA1614210

Type: Binding

Description: PubChem BioAssay. Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase. (Class of assay: confirmatory)

Format: BAO_0000357

Organism: Pseudomonas aeruginosa

Target: Beta Lactamase(ALA1293246)

Document: ALA1201862

PubChem Source: AID:1919

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1614210

IC50

Total(123)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
229.24	1.80	1.80
289.34	3.34	3.34
429.47	2.97	2.97
457.52	3.69	3.69
323.78	3.06	3.06
403.43	2.48	2.48
369.81	2.73	2.73
368.78	3.36	3.36
353.45	2.69	2.69
274.39	3.38	3.38
287.34	2.88	2.88
392.44	2.93	2.93
378.85	3.17	3.17
382.90	2.95	2.95
357.37	1.95	1.95
420.42	3.47	3.47
277.28	1.84	1.84
352.36	2.92	2.92
374.45	2.79	2.79
419.44	2.70	2.70
340.77	4.52	4.52
442.50	3.79	3.79
237.35	2.87	2.87
257.32	2.88	2.88
223.30	2.48	2.48
360.53	3.25	3.25
359.38	2.12	2.12
285.35	3.42	3.42
371.40	3.26	3.26
380.50	3.06	3.06
267.36	3.53	3.53
312.76	4.02	4.02
416.30	1.92	1.92
370.53	2.99	2.99
303.41	3.41	3.41
257.36	3.52	3.52
181.26	1.63	1.63
396.56	3.73	3.73
449.53	2.82	2.82
449.63	3.72	3.72
368.39	4.16	4.16
441.54	4.35	4.35
441.53	3.36	3.36
465.50	3.40	3.40
303.34	3.06	3.06
433.58	3.13	3.13
221.28	2.09	2.09
362.41	3.54	3.54
408.37	2.41	2.41
447.60	4.86	4.86
267.36	3.28	3.28
368.21	3.52	3.52
299.36	1.80	1.80
273.39	3.34	3.34
254.27	1.14	1.14
219.31	2.48	2.48
371.42	3.01	3.01
185.30	2.10	2.10
458.22	3.38	3.38
358.47	1.59	1.59
356.49	3.44	3.44
363.42	2.04	2.04
290.38	4.32	4.32
339.46	4.10	4.10
231.32	2.49	2.49
420.47	3.48	3.48
265.41	3.80	3.80
388.47	3.10	3.10
273.32	2.82	2.82
413.55	4.05	4.05
336.42	2.59	2.59
328.42	4.03	4.03
388.83	5.26	5.26
491.82	3.59	3.59
319.82	3.23	3.23
234.19	2.99	2.99
237.33	2.94	2.94
449.46	4.08	4.08
404.47	2.80	2.80
384.55	3.38	3.38
370.46	4.55	4.55
404.52	3.52	3.52
359.38	2.17	2.17
417.46	2.82	2.82
228.27	1.54	1.54
261.35	2.41	2.41
271.78	2.42	2.42
285.80	2.73	2.73
377.43	3.32	3.32
356.50	2.75	2.75
371.39	2.04	2.04
323.14
389.39	3.39	3.39
359.38	2.17	2.17
372.30	4.72	4.72
264.22	2.07	2.07
260.08	2.15	2.15
316.45	3.90	3.90
240.22	1.38	1.38
293.35	3.97	3.97
420.47	3.48	3.48
415.44	2.66	2.66
443.50	3.30	3.30
367.34	-0.30	-0.30
418.52	2.82	2.82
283.28	1.30	1.30
276.29	3.77	3.77
388.47	3.10	3.10
253.40	3.40	3.40
351.36	2.00	2.00
366.51	2.57	2.57
321.41	3.57	3.57
318.33	0.67	0.67
258.35	2.81	2.81
484.38	5.05	5.05
454.15	4.35	4.35
484.38	5.05	5.05
369.38	3.83	3.83
360.44	2.96	2.96
272.38	3.07	3.07
289.36	1.97	1.97
317.25	2.38	2.38
348.36	0.67	0.67