Basic Information
ID: ALA1614220
Type: Binding
Description: PUBCHEM_BIOASSAY: Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). (Class of assay: confirmatory) [Related pubchem assays: 1830 (Summary AID.), 1800 (Primary screen (NS3 inhibitors).), 1943 (Confirmation screen (NS3 inhibitors).)]
Organism: Hepatitis C virus
Activity Charts
Bioactivity
Activity Types for Assay ALA1614220
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.33 | 4.57 | 4.57 |
| 385.38 | 3.96 | 3.96 |
| 371.33 | 4.42 | 4.42 |
| 435.48 | 5.14 | 5.14 |
| 404.26 | 3.76 | 3.76 |
| 301.32 | 2.44 | 2.44 |
| 385.44 | 3.87 | 3.87 |
| 373.41 | 4.82 | 4.82 |
| 390.47 | 2.81 | 2.81 |
| 451.86 | 4.48 | 4.48 |
| 466.55 | 4.33 | 4.33 |
| 285.73 | 4.54 | 4.54 |
| 243.31 | 2.84 | 2.84 |
| 280.32 | 3.27 | 3.27 |
| 526.66 | 5.89 | 5.89 |
| 343.32 | 2.32 | 2.32 |
| 522.49 | 4.69 | 4.69 |
| 388.38 | 5.08 | 5.08 |
| 407.81 | 3.93 | 3.93 |
| 410.52 | 6.17 | 6.17 |
| 412.47 | 5.05 | 5.05 |
| 329.79 | 3.92 | 3.92 |
| 373.46 | 4.72 | 4.72 |
| 326.38 | 3.93 | 3.93 |
| 336.35 | 3.12 | 3.12 |
| 373.29 | 4.90 | 4.90 |
| 368.39 | 4.25 | 4.25 |
| 450.50 | 5.11 | 5.11 |
| 458.95 | 3.93 | 3.93 |
| 470.48 | 5.25 | 5.25 |
| 346.21 | 3.25 | 3.25 |
| 338.37 | 3.05 | 3.05 |
| 401.45 | 4.05 | 4.05 |
| 493.94 | 0.03 | 0.03 |
| 417.45 | 3.75 | 3.75 |
| 524.62 | 4.18 | 4.18 |
| 468.53 | 6.03 | 6.03 |
| 308.75 | 3.84 | 3.84 |
| 280.32 | 3.27 | 3.27 |
| 425.49 | 4.06 | 4.06 |
| 413.10 | 4.89 | 4.89 |
| 398.49 | 1.94 | 1.94 |
| 486.50 | 5.21 | 5.21 |
| 450.49 | 5.24 | 5.24 |
| 478.55 | 5.73 | 5.73 |
| 407.50 | 4.81 | 4.81 |
| 446.48 | 5.10 | 5.10 |
| 402.26 | 2.61 | 2.61 |
| 397.81 | 4.61 | 4.61 |
| 403.53 | 3.91 | 3.91 |
| 438.53 | 4.85 | 4.85 |
| 464.57 | 4.71 | 4.71 |
| 412.45 | 4.19 | 4.19 |
| 444.53 | 5.17 | 5.17 |
| 435.48 | 5.14 | 5.14 |
| 324.41 | 4.54 | 4.54 |
| 457.54 | 5.04 | 5.04 |
| 416.48 | 4.53 | 4.53 |
| 445.55 | 4.36 | 4.36 |
| 280.32 | 3.27 | 3.27 |
| 498.51 | 3.94 | 3.94 |
| 477.50 | 4.43 | 4.43 |
| 304.29 | 2.35 | 2.35 |
| 458.51 | 4.97 | 4.97 |
| 401.51 | 4.56 | 4.56 |
| 478.60 | 4.85 | 4.85 |
| 329.40 | 3.95 | 3.95 |
| 375.22 | 3.81 | 3.81 |
| 378.52 | 5.11 | 5.11 |
| 424.48 | 4.53 | 4.53 |
| 474.49 | 4.20 | 4.20 |
| 423.43 | 5.60 | 5.60 |
| 286.71 | 3.30 | 3.30 |
| 399.49 | 6.05 | 6.05 |
| 421.41 | 4.70 | 4.70 |
| 231.25 | 1.93 | 1.93 |
| 391.47 | 2.15 | 2.15 |
| 534.66 | 5.33 | 5.33 |
| 542.59 | 3.91 | 3.91 |
| 417.46 | 4.77 | 4.77 |
| 465.50 | 5.15 | 5.15 |
| 372.22 | 4.57 | 4.57 |
| 364.40 | 2.24 | 2.24 |
| 456.45 | 5.46 | 5.46 |
| 373.35 | 2.33 | 2.33 |
| 226.24 | 1.72 | 1.72 |
| 417.49 | 5.11 | 5.11 |
| 386.04 | 4.71 | 4.71 |
| 500.51 | 5.25 | 5.25 |
| 442.43 | 5.15 | 5.15 |
| 365.30 | 3.59 | 3.59 |
| 392.44 | 4.43 | 4.43 |
| 418.52 | 5.36 | 5.36 |
| 331.37 | 4.26 | 4.26 |
| 410.42 | 4.99 | 4.99 |
| 374.23 | 3.76 | 3.76 |
| 452.47 | 3.90 | 3.90 |
| 460.44 | 4.53 | 4.53 |
| 413.10 | 4.89 | 4.89 |
| 314.37 | 4.40 | 4.40 |
| 328.35 | 2.12 | 2.12 |
| 466.49 | 5.55 | 5.55 |
| 461.54 | 5.13 | 5.13 |
| 353.38 | 4.53 | 4.53 |
| 277.37 | 3.73 | 3.73 |
| 416.46 | 2.72 | 2.72 |
| 414.42 | 4.82 | 4.82 |
| 460.44 | 4.53 | 4.53 |
| 288.30 | 4.27 | 4.27 |
| 428.49 | 5.00 | 5.00 |
| 506.54 | 4.22 | 4.22 |
| 462.48 | 4.63 | 4.63 |
| 383.43 | 2.76 | 2.76 |
| 351.50 | 4.64 | 4.64 |
| 313.47 | 3.32 | 3.32 |
| 356.28 | 3.46 | 3.46 |
| 478.89 | -0.44 | -0.44 |
| 383.86 | 4.37 | 4.37 |
| 508.53 | 3.97 | 3.97 |
| 407.45 | 1.60 | 1.60 |
| 445.18 | 3.68 | 3.68 |
| 428.56 | 4.02 | 4.02 |
| 417.47 | 4.48 | 4.48 |
| 399.23 | 5.36 | 5.36 |
| 449.53 | 3.30 | 3.30 |