Basic Information
ID: ALA1614223
Type: Binding
Description: PUBCHEM_BIOASSAY: Identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a time resolved fluorescence resonance energy transfer (TR-FRET) assay. Counterscreen (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1434, AID1496, AID1502, AID1550, AID1560, AID1645]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614223
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 293.33 | 3.30 | 3.30 |
| 301.31 | 2.87 | 2.87 |
| 285.39 | 4.93 | 4.93 |
| 321.80 | 2.85 | 2.85 |
| 579.67 | 5.05 | 5.05 |
| 443.44 | 2.84 | 2.84 |
| 253.30 | 2.72 | 2.72 |
| 254.33 | 2.99 | 2.99 |
| 413.48 | 4.04 | 4.04 |
| 407.93 | 4.87 | 4.87 |
| 194.22 | 1.62 | 1.62 |
| 548.40 | 4.62 | 4.62 |
| 274.67 | 1.33 | 1.33 |
| 396.36 | 2.63 | 2.63 |
| 282.39 | 2.24 | 2.24 |
| 494.57 | 6.24 | 6.24 |
| 389.45 | 2.63 | 2.63 |
| 421.46 | 4.54 | 4.54 |
| 415.91 | 3.96 | 3.96 |
| 446.49 | 2.91 | 2.91 |
| 380.30 | 4.43 | 4.43 |
| 460.49 | 1.52 | 1.52 |
| 341.40 | 1.93 | 1.93 |
| 252.32 | 2.77 | 2.77 |
| 254.31 | 3.01 | 3.01 |
| 439.48 | 3.01 | 3.01 |
| 257.29 | 2.25 | 2.25 |
| 354.79 | 3.82 | 3.82 |
| 373.51 | 3.81 | 3.81 |
| 438.56 | 5.08 | 5.08 |
| 431.50 | 3.06 | 3.06 |
| 428.44 | 4.51 | 4.51 |
| 303.79 | 2.85 | 2.85 |
| 336.40 | 4.05 | 4.05 |
| 397.41 | 3.04 | 3.04 |
| 320.40 | 2.61 | 2.61 |
| 310.25 | 3.35 | 3.35 |
| 462.51 | 4.44 | 4.44 |
| 403.49 | 4.55 | 4.55 |
| 330.34 | 3.27 | 3.27 |
| 472.51 | 1.45 | 1.45 |
| 470.55 | 4.81 | 4.81 |
| 420.47 | 1.87 | 1.87 |
| 444.53 | 5.17 | 5.17 |
| 412.54 | 3.49 | 3.49 |
| 373.41 | 3.21 | 3.21 |
| 429.46 | 4.07 | 4.07 |
| 433.53 | 4.45 | 4.45 |
| 416.48 | 4.53 | 4.53 |
| 194.22 | 1.62 | 1.62 |
| 401.51 | 3.42 | 3.42 |
| 432.46 | 2.60 | 2.60 |
| 486.41 | 5.46 | 5.46 |
| 371.47 | 1.50 | 1.50 |
| 264.28 | 2.66 | 2.66 |
| 323.39 | 3.92 | 3.92 |
| 474.49 | 4.20 | 4.20 |
| 363.42 | 3.19 | 3.19 |
| 339.78 | 3.68 | 3.68 |
| 245.28 | 2.23 | 2.23 |
| 425.45 | 2.70 | 2.70 |
| 363.48 | 2.58 | 2.58 |
| 304.40 | 3.90 | 3.90 |
| 483.53 | 4.24 | 4.24 |
| 418.48 | 3.95 | 3.95 |
| 570.06 | 5.30 | 5.30 |
| 224.26 | 3.52 | 3.52 |
| 491.55 | 3.11 | 3.11 |
| 385.54 | 5.33 | 5.33 |
| 339.40 | 3.85 | 3.85 |
| 240.26 | 2.68 | 2.68 |
| 415.45 | 3.84 | 3.84 |
| 418.48 | 3.95 | 3.95 |
| 409.44 | 2.61 | 2.61 |
| 492.56 | 2.62 | 2.62 |
| 328.38 | 4.05 | 4.05 |
| 372.43 | 5.15 | 5.15 |
| 423.43 | 4.19 | 4.19 |
| 404.90 | 4.21 | 4.21 |
| 340.34 | 2.99 | 2.99 |
| 411.38 | 2.50 | 2.50 |
| 449.47 | 3.52 | 3.52 |
| 439.54 | 6.52 | 6.52 |
| 482.50 | 3.52 | 3.52 |
| 462.55 | 5.02 | 5.02 |
| 465.47 | 3.22 | 3.22 |
| 482.97 | 5.37 | 5.37 |
| 278.31 | 2.99 | 2.99 |