Basic Information
ID: ALA1614226
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescence-based counterscreen assay for KLF5 inhibitors: dose response cell-based high throughput screening assay to identify cytotoxic compounds using the IEC-6 intestinal epithelial cell line. (Class of assay: confirmatory) [Related pubchem assays: 1700 (Primary screen.), 1834 (Confirmation screen.), 1858 (Summary AID.), 1905 (Counterscreen.)]
Cell type: Epithelial cell
Activity Charts
Bioactivity
Activity Types for Assay ALA1614226
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 204.25 | 2.40 | 2.40 |
| 584.66 | -1.51 | -1.51 |
| 299.33 | 4.47 | 4.47 |
| 273.30 | 3.95 | 3.95 |
| 322.39 | 4.22 | 4.22 |
| 237.26 | 3.08 | 3.08 |
| 332.40 | 3.88 | 3.88 |
| 264.31 | 1.05 | 1.05 |
| 295.34 | 3.60 | 3.60 |
| 350.42 | 4.00 | 4.00 |
| 364.49 | 4.07 | 4.07 |
| 382.39 | 0.80 | 0.80 |
| 343.38 | 3.91 | 3.91 |
| 324.29 | 3.03 | 3.03 |
| 317.27 | 5.37 | 5.37 |
| 272.26 | 1.83 | 1.83 |
| 283.33 | 2.51 | 2.51 |
| 281.36 | 3.32 | 3.32 |
| 267.33 | 3.80 | 3.80 |
| 328.80 | 4.06 | 4.06 |
| 414.49 | 4.39 | 4.39 |
| 265.32 | 3.38 | 3.38 |
| 402.47 | 2.31 | 2.31 |
| 285.30 | 2.71 | 2.71 |
| 330.45 | 3.70 | 3.70 |
| 345.82 | 3.25 | 3.25 |
| 297.35 | 2.82 | 2.82 |
| 251.29 | 2.73 | 2.73 |
| 367.50 | 5.18 | 5.18 |
| 315.35 | 2.81 | 2.81 |
| 284.34 | 3.96 | 3.96 |
| 283.72 | 3.96 | 3.96 |
| 301.32 | 2.57 | 2.57 |
| 343.45 | 4.48 | 4.48 |
| 369.44 | 3.96 | 3.96 |
| 259.38 | 3.44 | 3.44 |
| 251.29 | 3.12 | 3.12 |
| 262.31 | 3.80 | 3.80 |
| 314.37 | 3.57 | 3.57 |
| 328.35 | 3.00 | 3.00 |
| 412.54 | 4.32 | 4.32 |
| 303.41 | 3.65 | 3.65 |
| 330.37 | 3.63 | 3.63 |
| 301.30 | 1.27 | 1.27 |
| 287.32 | 2.91 | 2.91 |
| 270.31 | 3.24 | 3.24 |
| 297.36 | 2.86 | 2.86 |
| 268.31 | 3.45 | 3.45 |
| 289.72 | 2.52 | 2.52 |
| 370.21 | 3.02 | 3.02 |
| 282.34 | 3.66 | 3.66 |
| 269.30 | 2.18 | 2.18 |
| 266.30 | 3.29 | 3.29 |
| 307.42 | 3.49 | 3.49 |
| 283.33 | 2.43 | 2.43 |
| 359.41 | 4.58 | 4.58 |
| 302.31 | 2.91 | 2.91 |
| 309.37 | 2.81 | 2.81 |
| 276.72 | 3.23 | 3.23 |
| 348.81 | 3.70 | 3.70 |
| 474.60 | 3.52 | 3.52 |
| 289.34 | 4.22 | 4.22 |
| 347.42 | 3.49 | 3.49 |
| 291.35 | 3.57 | 3.57 |
| 315.81 | 3.02 | 3.02 |
| 283.33 | 3.51 | 3.51 |
| 325.42 | 2.95 | 2.95 |
| 428.33 | 4.03 | 4.03 |
| 300.27 | 2.76 | 2.76 |
| 357.45 | 3.26 | 3.26 |
| 329.31 | 3.22 | 3.22 |
| 338.37 | 3.17 | 3.17 |
| 296.37 | 3.46 | 3.46 |
| 278.40 | 3.73 | 3.73 |
| 265.32 | 3.15 | 3.15 |
| 394.50 | 3.84 | 3.84 |
| 273.34 | 2.45 | 2.45 |
| 586.68 | -1.44 | -1.44 |
| 582.69 | 3.03 | 3.03 |
| 367.43 | 3.71 | 3.71 |
| 299.33 | 2.50 | 2.50 |
| 301.73 | 3.48 | 3.48 |
| 395.43 | 3.06 | 3.06 |
| 318.40 | 2.40 | 2.40 |
| 335.39 | 1.75 | 1.75 |
| 368.35 | 2.76 | 2.76 |
| 279.30 | 3.31 | 3.31 |
| 264.67 | 1.99 | 1.99 |
| 459.63 | 3.57 | 3.57 |
| 275.70 | 2.20 | 2.20 |
| 342.35 | 2.33 | 2.33 |
| 503.15 | 4.59 | 4.59 |
| 283.33 | 2.90 | 2.90 |
| 419.44 | 3.43 | 3.43 |
| 339.35 | 2.65 | 2.65 |
| 339.35 | 2.65 | 2.65 |
| 364.20 | 2.71 | 2.71 |
| 425.45 | 0.93 | 0.93 |
| 320.15 | 2.31 | 2.31 |
| 359.18 | 3.66 | 3.66 |
| 387.44 | 4.05 | 4.05 |
| 379.21 | 2.94 | 2.94 |
| 278.70 | 2.29 | 2.29 |
| 401.50 | 2.96 | 2.96 |
| 345.71 | 3.91 | 3.91 |
| 370.42 | 3.79 | 3.79 |
| 334.17 | 2.62 | 2.62 |
| 301.30 | 2.78 | 2.78 |
| 291.31 | 2.70 | 2.70 |
| 399.24 | 4.00 | 4.00 |
| 321.38 | 2.50 | 2.50 |
| 307.35 | 3.25 | 3.25 |
| 320.35 | 3.99 | 3.99 |
| 369.36 | 2.96 | 2.96 |
| 369.38 | 2.66 | 2.66 |
| 388.23 | 2.65 | 2.65 |
| 326.35 | 3.65 | 3.65 |
| 274.35 | 2.11 | 2.11 |
| 334.35 | 4.38 | 4.38 |
| 288.26 | 2.15 | 2.15 |
| 305.34 | 3.01 | 3.01 |
| 286.29 | 2.55 | 2.55 |