Basic Information
ID: ALA1614228
Type: Binding
Description: PUBCHEM_BIOASSAY: Counter Screen using XIAP-Bir3 for Chemical Antagonists of Bir1/2 domains of IAP-family anti-apoptotic proteins. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1018, AID1449, AID1514, AID1638, AID1749, AID1750, AID488957, AID488963]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614228
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 152.15 | 0.80 | 0.80 |
| 239.23 | 1.75 | 1.75 |
| 373.50 | 3.58 | 3.58 |
| 835.09 | 2.20 | 2.20 |
| 355.42 | 4.72 | 4.72 |
| 476.58 | 3.98 | 3.98 |
| 413.34 | 4.45 | 4.45 |
| 355.42 | 2.51 | 2.51 |
| 423.90 | 4.45 | 4.45 |
| 365.43 | 2.90 | 2.90 |
| 501.68 | 3.45 | 3.45 |
| 507.02 | 5.00 | 5.00 |
| 316.40 | 2.56 | 2.56 |
| 416.59 | 5.19 | 5.19 |
| 292.38 | 1.31 | 1.31 |
| 203.27 | 3.01 | 3.01 |
| 514.61 | 5.39 | 5.39 |
| 505.53 | 3.70 | 3.70 |
| 316.34 | 1.29 | 1.29 |
| 297.33 | 1.06 | 1.06 |
| 460.53 | 5.88 | 5.88 |
| 355.39 | 2.40 | 2.40 |
| 239.32 | 3.76 | 3.76 |
| 461.97 | 4.94 | 4.94 |
| 356.38 | 1.44 | 1.44 |
| 325.43 | 2.31 | 2.31 |
| 276.29 | 2.30 | 2.30 |
| 269.37 | 2.10 | 2.10 |
| 345.23 | 3.84 | 3.84 |
| 386.86 | 5.15 | 5.15 |
| 287.29 | 0.63 | 0.63 |
| 463.99 | 2.76 | 2.76 |
| 287.32 | 2.40 | 2.40 |
| 500.51 | 3.87 | 3.87 |
| 286.24 | 2.02 | 2.02 |
| 361.26 | 4.86 | 4.86 |
| 288.28 | 2.90 | 2.90 |
| 329.44 | 2.25 | 2.25 |
| 343.42 | 4.38 | 4.38 |
| 289.29 | 2.21 | 2.21 |
| 296.39 | 1.02 | 1.02 |
| 307.40 | 2.96 | 2.96 |
| 196.29 | 0.00 | 0.00 |
| 402.50 | 3.91 | 3.91 |
| 327.79 | 2.56 | 2.56 |
| 318.79 | 3.99 | 3.99 |
| 338.36 | 3.03 | 3.03 |
| 287.17 | 4.32 | 4.32 |
| 396.51 | 3.85 | 3.85 |
| 276.36 | 2.94 | 2.94 |
| 362.40 | 4.32 | 4.32 |
| 430.51 | 2.92 | 2.92 |
| 243.76 | 3.20 | 3.20 |
| 397.45 | 1.67 | 1.67 |
| 341.44 | 4.02 | 4.02 |
| 366.53 | 3.29 | 3.29 |
| 515.69 | 4.55 | 4.55 |
| 333.24 | 3.13 | 3.13 |
| 285.73 | 3.15 | 3.15 |
| 247.39 | 3.44 | 3.44 |
| 224.65 | 2.30 | 2.30 |
| 314.38 | 2.52 | 2.52 |
| 366.37 | 3.11 | 3.11 |
| 295.34 | 3.29 | 3.29 |
| 336.83 | 3.69 | 3.69 |
| 384.46 | 4.22 | 4.22 |
| 386.97 | 2.87 | 2.87 |
| 456.93 | 3.45 | 3.45 |
| 316.34 | 2.76 | 2.76 |
| 256.26 | 1.45 | 1.45 |
| 363.68 | 3.45 | 3.45 |
| 402.49 | 4.42 | 4.42 |
| 404.62 | 4.12 | 4.12 |
| 327.40 | 3.74 | 3.74 |
| 307.33 | 2.72 | 2.72 |
| 349.42 | 2.52 | 2.52 |
| 353.83 | 3.01 | 3.01 |
| 272.33 | 2.87 | 2.87 |
| 269.30 | 3.82 | 3.82 |
| 343.43 | 4.57 | 4.57 |
| 341.80 | 4.56 | 4.56 |
| 370.47 | 3.51 | 3.51 |
| 268.28 | 2.74 | 2.74 |
| 375.48 | 2.94 | 2.94 |
| 330.35 | 3.67 | 3.67 |
| 487.54 | 2.95 | 2.95 |
| 483.57 | 3.69 | 3.69 |
| 287.11 | 1.44 | 1.44 |
| 428.91 | 3.89 | 3.89 |
| 277.32 | 3.94 | 3.94 |
| 485.50 | 3.80 | 3.80 |
| 448.91 | 4.91 | 4.91 |
| 368.43 | 2.77 | 2.77 |
| 373.46 | 4.09 | 4.09 |
| 375.48 | 3.61 | 3.61 |
| 270.31 | 1.77 | 1.77 |
| 463.56 | 3.21 | 3.21 |
| 300.36 | 2.41 | 2.41 |
| 506.63 | 5.30 | 5.30 |
| 264.37 | 3.35 | 3.35 |
| 262.27 | 2.65 | 2.65 |
| 518.57 | 3.71 | 3.71 |
| 465.41 | 4.88 | 4.88 |
| 390.48 | 2.83 | 2.83 |
| 423.47 | 3.46 | 3.46 |
| 403.45 | 4.15 | 4.15 |
| 294.31 | 3.42 | 3.42 |
| 287.75 | 2.38 | 2.38 |
| 283.24 | 1.59 | 1.59 |
| 358.39 | 2.83 | 2.83 |
| 408.42 | 4.65 | 4.65 |
| 425.28 | 4.16 | 4.16 |
| 305.76 | 3.16 | 3.16 |
| 443.61 | 2.90 | 2.90 |
| 392.51 | 4.79 | 4.79 |
| 362.43 | 2.19 | 2.19 |
| 379.44 | 3.56 | 3.56 |
| 444.58 | 3.56 | 3.56 |
| 357.43 | 4.00 | 4.00 |
| 355.53 | 4.08 | 4.08 |
| 258.32 | 3.12 | 3.12 |
| 401.50 | 3.46 | 3.46 |
| 363.37 | 3.40 | 3.40 |
| 471.54 | 3.05 | 3.05 |
| 453.45 | 5.79 | 5.79 |
| 322.75 | 1.26 | 1.26 |
| 374.44 | 1.92 | 1.92 |
| 425.28 | 4.53 | 4.53 |
| 258.32 | 0.88 | 0.88 |
| 480.61 | 1.92 | 1.92 |
| 301.30 | 2.30 | 2.30 |
| 337.41 | 0.46 | 0.46 |
| 384.43 | 2.94 | 2.94 |
| 450.96 | 4.01 | 4.01 |
| 302.36 | 2.26 | 2.26 |
| 308.74 | 3.54 | 3.54 |
| 445.59 | 2.88 | 2.88 |
| 310.42 | 3.42 | 3.42 |
| 345.40 | 4.51 | 4.51 |
| 349.43 | 2.70 | 2.70 |
| 472.94 | 4.23 | 4.23 |
| 278.19 | 2.13 | 2.13 |
| 282.71 | 2.77 | 2.77 |
| 262.26 | 2.15 | 2.15 |
| 286.40 | 3.02 | 3.02 |
| 405.48 | 3.68 | 3.68 |
| 394.52 | 4.95 | 4.95 |
| 307.37 | 5.02 | 5.02 |
| 499.52 | 4.55 | 4.55 |
| 342.42 | 3.40 | 3.40 |
| 221.21 | 1.17 | 1.17 |
| 407.61 | 3.91 | 3.91 |
| 246.34 | 2.49 | 2.49 |
| 318.29 | 2.16 | 2.16 |
| 315.38 | 4.31 | 4.31 |
| 450.49 | 3.92 | 3.92 |
| 406.44 | 3.86 | 3.86 |
| 324.36 | 2.90 | 2.90 |
| 306.37 | 3.24 | 3.24 |
| 550.53 | 5.50 | 5.50 |
| 274.32 | 1.06 | 1.06 |
| 338.43 | 1.63 | 1.63 |
| 372.49 | 2.85 | 2.85 |
| 387.30 | 5.06 | 5.06 |
| 307.33 | 2.16 | 2.16 |
| 312.83 | 5.09 | 5.09 |
| 439.31 | 4.76 | 4.76 |
| 334.40 | 1.09 | 1.09 |
| 498.54 | 3.08 | 3.08 |
| 396.92 | 3.33 | 3.33 |
| 307.37 | 2.65 | 2.65 |
| 406.12 | 2.66 | 2.66 |
| 319.38 | 2.16 | 2.16 |
| 296.32 | 3.38 | 3.38 |
| 432.53 | 3.91 | 3.91 |
| 238.25 | 4.09 | 4.09 |
| 221.28 | 0.85 | 0.85 |
| 346.45 | 3.11 | 3.11 |
| 354.36 | 2.38 | 2.38 |
| 340.36 | 0.28 | 0.28 |
| 367.32 | 3.25 | 3.25 |
| 333.48 | 0.91 | 0.91 |
| 318.33 | 2.22 | 2.22 |
| 434.51 | 2.37 | 2.37 |
| 300.31 | 3.09 | 3.09 |
| 337.46 | 3.02 | 3.02 |
| 374.51 | 2.32 | 2.32 |
| 474.65 | 4.23 | 4.23 |
| 429.44 | 3.67 | 3.67 |
| 327.50 | 4.11 | 4.11 |
| 411.44 | 4.56 | 4.56 |
| 388.49 | 1.81 | 1.81 |
| 259.29 | 2.26 | 2.26 |
| 212.29 | 0.96 | 0.96 |
| 409.57 | 3.08 | 3.08 |
| 191.23 | 1.52 | 1.52 |
| 318.40 | 5.46 | 5.46 |
| 361.47 | 4.35 | 4.35 |
| 310.35 | 3.66 | 3.66 |
| 298.34 | 2.62 | 2.62 |
| 373.87 | 4.33 | 4.33 |
| 475.62 | 2.90 | 2.90 |
| 531.62 | 2.33 | 2.33 |
| 305.72 | 2.41 | 2.41 |
| 429.89 | 3.80 | 3.80 |
| 240.26 | 2.04 | 2.04 |
| 486.55 | 1.00 | 1.00 |
| 377.35 | 0.39 | 0.39 |
| 317.35 | 3.08 | 3.08 |
| 269.35 | 2.53 | 2.53 |
| 363.40 | 1.06 | 1.06 |
| 375.46 | 4.50 | 4.50 |
| 310.26 | 2.16 | 2.16 |
| 341.41 | 2.84 | 2.84 |
| 392.48 | 4.44 | 4.44 |
| 421.43 | 2.39 | 2.39 |
| 320.42 | 5.30 | 5.30 |
| 397.50 | 2.66 | 2.66 |
| 416.86 | 3.10 | 3.10 |
| 288.30 | 4.27 | 4.27 |
| 352.39 | 3.48 | 3.48 |
| 308.36 | 4.10 | 4.10 |
| 512.97 | 2.92 | 2.92 |
| 367.46 | 2.53 | 2.53 |
| 424.32 | 2.67 | 2.67 |
| 488.55 | 4.20 | 4.20 |
| 518.82 | 3.52 | 3.52 |
| 303.28 | 0.70 | 0.70 |
| 427.49 | 3.05 | 3.05 |
| 423.47 | 5.51 | 5.51 |
| 284.32 | 3.56 | 3.56 |
| 283.33 | 4.01 | 4.01 |
| 352.46 | 3.38 | 3.38 |
| 284.28 | 2.06 | 2.06 |
| 226.30 | 1.35 | 1.35 |
| 333.44 | 3.73 | 3.73 |
| 399.36 | 2.21 | 2.21 |
| 325.46 | 4.12 | 4.12 |