ID: ALA1614254
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen assay for PERK inhibitors: Dose response cell-based high throughput screening assay to measure inhibition of PERK at 6 hours. (Class of assay: confirmatory) [Related pubchem assays: 1522, 1416 ]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1614254
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
348.36 | 2.08 | 2.08 |
301.69 | -1.33 | -1.33 |
230.26 | 2.69 | 2.69 |
220.22 | 2.62 | 2.62 |
256.30 | 3.13 | 3.13 |
438.51 | 3.43 | 3.43 |
257.17 | 1.67 | 1.67 |
342.35 | 3.06 | 3.06 |
267.31 | 3.57 | 3.57 |
352.24 | 4.10 | 4.10 |
299.44 | 2.08 | 2.08 |
296.31 | 3.72 | 3.72 |
262.27 | 1.65 | 1.65 |
254.31 | 1.94 | 1.94 |
360.46 | 2.60 | 2.60 |
419.48 | 1.93 | 1.93 |
341.29 | 2.91 | 2.91 |
377.52 | 4.31 | 4.31 |
233.30 | 2.15 | 2.15 |
309.35 | 3.20 | 3.20 |
230.24 | 2.58 | 2.58 |
450.59 | 1.95 | 1.95 |
267.31 | 1.19 | 1.19 |
443.50 | 3.26 | 3.26 |
307.38 | 0.72 | 0.72 |
242.23 | 2.66 | 2.66 |
209.28 | 1.11 | 1.11 |
274.11 | 1.96 | 1.96 |
212.20 | 2.27 | 2.27 |
307.72 | 3.43 | 3.43 |
343.34 | 2.72 | 2.72 |
325.39 | 0.49 | 0.49 |
225.76 | 3.61 | 3.61 |
298.34 | 3.93 | 3.93 |
326.39 | 4.22 | 4.22 |
330.34 | 2.72 | 2.72 |
381.28 | 4.30 | 4.30 |
249.27 | 1.30 | 1.30 |
305.26 | 1.37 | 1.37 |
446.55 | -0.20 | -0.20 |
179.17 | 1.20 | 1.20 |
264.35 | 2.86 | 2.86 |
258.66 | 2.54 | 2.54 |
300.24 | 2.96 | 2.96 |
271.27 | 0.40 | 0.40 |
197.24 | -0.14 | -0.14 |
266.26 | 0.27 | 0.27 |
319.43 | 4.07 | 4.07 |
386.49 | 2.10 | 2.10 |
240.09 | 3.80 | 3.80 |
318.27 | 3.30 | 3.30 |
271.37 | 1.77 | 1.77 |
250.21 | 0.85 | 0.85 |
142.25 | 0.82 | 0.82 |
158.18 | 0.73 | 0.73 |
350.40 | 2.09 | 2.09 |
154.12 | 1.00 | 1.00 |
300.32 | 2.80 | 2.80 |
446.49 | 0.14 | 0.14 |
300.32 | 2.80 | 2.80 |
347.43 | 3.00 | 3.00 |
324.36 | 1.72 | 1.72 |
320.37 | 3.42 | 3.42 |
305.33 | 1.48 | 1.48 |
413.50 | 3.64 | 3.64 |
203.25 | 1.06 | 1.06 |
297.35 | 3.83 | 3.83 |
518.70 | 3.39 | 3.39 |
218.21 | 1.05 | 1.05 |
232.26 | 1.92 | 1.92 |
401.49 | 1.80 | 1.80 |
350.75 | 3.86 | 3.86 |
300.34 | 1.13 | 1.13 |
297.36 | 3.91 | 3.91 |
441.87 | 1.59 | 1.59 |
257.38 | 2.00 | 2.00 |
300.38 | 3.17 | 3.17 |
357.41 | 0.63 | 0.63 |
300.11 | 3.18 | 3.18 |
210.22 | 0.20 | 0.20 |
180.17 | 1.01 | 1.01 |
323.61 | 3.63 | 3.63 |
346.41 | 5.17 | 5.17 |
380.43 | 2.58 | 2.58 |
303.32 | 1.54 | 1.54 |
426.24 | 6.48 | 6.48 |
247.22 | 2.20 | 2.20 |
276.34 | 3.25 | 3.25 |
154.21 | 1.25 | 1.25 |
328.41 | 1.50 | 1.50 |
307.38 | 1.54 | 1.54 |
261.80 | 3.38 | 3.38 |
327.30 | -2.28 | -2.28 |
343.48 | 1.96 | 1.96 |
445.50 | 2.85 | 2.85 |
244.25 | 1.92 | 1.92 |
350.43 | 1.65 | 1.65 |
257.12 | 3.23 | 3.23 |
211.24 | 1.64 | 1.64 |
261.37 | 2.60 | 2.60 |
248.28 | 1.30 | 1.30 |
499.60 | 4.02 | 4.02 |
317.37 | 2.77 | 2.77 |
188.19 | 1.75 | 1.75 |
323.39 | 1.15 | 1.15 |
290.24 | 0.04 | 0.04 |
341.37 | 1.30 | 1.30 |
284.34 | 3.02 | 3.02 |
335.80 | 4.52 | 4.52 |
245.28 | 1.57 | 1.57 |
221.25 | 1.08 | 1.08 |
295.34 | 1.71 | 1.71 |
280.38 | 0.02 | 0.02 |
225.25 | 1.85 | 1.85 |
294.15 | 3.03 | 3.03 |
275.23 | 0.30 | 0.30 |
424.41 | 1.85 | 1.85 |
323.42 | 3.86 | 3.86 |