Basic Information
ID: ALA1614255
Type: Binding
Description: PUBCHEM_BIOASSAY: HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. (Class of assay: confirmatory) [Related pubchem assays: 1220 ]
Format: BAO_0000357
Organism: Homo sapiens
Target: Mannose-6-phosphate isomerase(ALA2758)
Document: ALA1201862
PubChem Source: AID:1209
Activity Charts
Bioactivity
Activity Types for Assay ALA1614255
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.23 | 2.31 | 2.31 |
| 318.81 | 3.12 | 3.12 |
| 258.23 | 2.32 | 2.32 |
| 178.14 | 1.20 | 1.20 |
| 361.35 | 1.13 | 1.13 |
| 296.28 | 3.24 | 3.24 |
| 263.41 | 3.59 | 3.59 |
| 363.24 | 0.45 | 0.45 |
| 413.52 | 3.53 | 3.53 |
| 337.17 | 2.43 | 2.43 |
| 409.49 | 1.70 | 1.70 |
| 280.78 | 3.45 | 3.45 |
| 405.48 | 3.63 | 3.63 |
| 420.47 | 4.80 | 4.80 |
| 269.26 | 3.08 | 3.08 |
| 224.33 | 3.87 | 3.87 |
| 336.44 | 5.32 | 5.32 |
| 333.24 | 3.13 | 3.13 |
| 333.19 | 3.08 | 3.08 |
| 418.32 | 6.29 | 6.29 |
| 291.33 | 2.22 | 2.22 |
| 229.33 | 3.70 | 3.70 |
| 337.38 | 1.87 | 1.87 |
| 314.18 | 2.17 | 2.17 |
| 314.38 | 1.04 | 1.04 |
| 274.11 | 1.07 | 1.07 |
| 252.21 | 2.02 | 2.02 |
| 322.18 | 0.56 | 0.56 |
| 361.38 | 0.44 | 0.44 |
| 371.44 | 3.35 | 3.35 |
| 376.51 | 5.18 | 5.18 |
| 344.39 | 3.98 | 3.98 |
| 276.37 | 3.15 | 3.15 |
| 321.41 | 3.67 | 3.67 |
| 329.22 | 3.41 | 3.41 |
| 302.36 | 1.85 | 1.85 |
| 261.24 | 2.11 | 2.11 |
| 360.89 | 4.96 | 4.96 |
| 314.35 | 0.90 | 0.90 |
| 386.41 | 3.98 | 3.98 |
| 356.42 | 3.02 | 3.02 |
| 319.37 | 3.21 | 3.21 |
| 294.27 | 2.77 | 2.77 |
| 279.39 | 2.57 | 2.57 |
| 369.38 | 3.52 | 3.52 |
| 262.26 | 2.92 | 2.92 |
| 340.41 | 1.41 | 1.41 |
| 384.40 | -1.24 | -1.24 |
| 202.21 | 1.50 | 1.50 |
| 409.41 | 4.30 | 4.30 |
| 299.36 | 3.67 | 3.67 |
| 301.29 | 2.48 | 2.48 |
| 237.35 | 2.78 | 2.78 |
| 386.79 | 3.99 | 3.99 |
| 474.49 | 4.20 | 4.20 |
| 231.29 | 1.63 | 1.63 |
| 324.36 | 1.42 | 1.42 |
| 316.39 | 2.35 | 2.35 |
| 280.78 | 3.71 | 3.71 |
| 259.26 | 2.42 | 2.42 |
| 267.38 | 2.78 | 2.78 |
| 180.24 | 1.03 | 1.03 |
| 432.91 | 3.84 | 3.84 |
| 440.33 | 5.11 | 5.11 |
| 383.52 | 4.54 | 4.54 |
| 231.25 | 1.27 | 1.27 |
| 264.33 | 3.86 | 3.86 |
| 368.34 | 3.74 | 3.74 |
| 326.38 | 2.67 | 2.67 |
| 368.44 | 3.82 | 3.82 |
| 260.39 | 3.83 | 3.83 |
| 238.34 | 2.43 | 2.43 |
| 434.43 | 4.43 | 4.43 |
| 197.24 | 2.84 | 2.84 |
| 226.32 | 3.46 | 3.46 |
| 285.17 | 1.63 | 1.63 |
| 260.37 | 3.13 | 3.13 |
| 197.24 | 2.82 | 2.82 |
| 241.29 | 3.47 | 3.47 |
| 368.44 | 2.53 | 2.53 |
| 384.44 | 1.30 | 1.30 |
| 211.25 | 0.26 | 0.26 |
| 338.37 | 2.44 | 2.44 |
| 429.48 | 4.11 | 4.11 |
| 427.37 | 1.73 | 1.73 |
| 548.58 | 4.60 | 4.60 |
| 343.41 | 3.41 | 3.41 |
| 368.44 | 1.60 | 1.60 |
| 382.47 | 1.90 | 1.90 |
| 327.38 | 2.26 | 2.26 |
| 354.37 | 2.25 | 2.25 |
| 333.30 | 0.47 | 0.47 |
| 279.32 | 1.39 | 1.39 |
| 336.31 | 3.01 | 3.01 |
| 283.33 | 3.47 | 3.47 |
| 253.74 | 2.96 | 2.96 |
| 295.37 | 2.82 | 2.82 |
| 301.35 | 4.18 | 4.18 |
| 288.78 | 3.11 | 3.11 |
| 338.37 | 2.54 | 2.54 |