Basic Information
ID: ALA1614283
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1707, 1708 ]
Format: BAO_0000019
Organism: Homo sapiens
Target: DNA-(apurinic or apyrimidinic site) lyase(ALA5619)
Document: ALA1201862
PubChem Source: AID:1705
Activity Charts
Bioactivity
Activity Types for Assay ALA1614283
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 168.15 | 1.22 | 1.22 |
| 270.24 | 2.58 | 2.58 |
| 252.35 | 0.60 | 0.60 |
| 211.22 | 0.44 | 0.44 |
| 1202.63 | ||
| 348.45 | 4.14 | 4.14 |
| 440.42 | 0.24 | 0.24 |
| 422.35 | 2.45 | 2.45 |
| 562.67 | 7.50 | 7.50 |
| 325.54 | 5.13 | 5.13 |
| 314.34 | 3.03 | 3.03 |
| 246.31 | 4.49 | 4.49 |
| 322.19 | 0.32 | 0.32 |
| 211.22 | 0.44 | 0.44 |
| 110.11 | 1.10 | 1.10 |
| 261.23 | 1.45 | 1.45 |
| 302.24 | 1.99 | 1.99 |
| 395.47 | 4.23 | 4.23 |
| 159.14 | -0.88 | -0.88 |
| 101.10 | -0.41 | -0.41 |
| 225.25 | 2.03 | 2.03 |
| 494.08 | 8.01 | 8.01 |
| 308.31 | 2.76 | 2.76 |
| 504.64 | -0.02 | -0.02 |
| 297.27 | 2.30 | 2.30 |
| 318.24 | 1.69 | 1.69 |
| 477.46 | -0.62 | -0.62 |
| 326.44 | 3.52 | 3.52 |
| 520.95 | 5.01 | 5.01 |
| 184.20 | 2.13 | 2.13 |
| 290.27 | 1.55 | 1.55 |
| 169.07 | -1.42 | -1.42 |
| 497.50 | 1.02 | 1.02 |
| 212.21 | 1.31 | 1.31 |
| 248.28 | 1.56 | 1.56 |
| 650.76 | 3.93 | 3.93 |
| 197.19 | 0.05 | 0.05 |
| 178.14 | 1.20 | 1.20 |
| 174.20 | -1.34 | -1.34 |
| 210.30 | 2.98 | 2.98 |
| 553.57 | 4.94 | 4.94 |
| 402.06 | 6.67 | 6.67 |
| 320.82 | 2.95 | 2.95 |
| 472.89 | 5.97 | 5.97 |
| 69.49 | -0.67 | -0.67 |
| 344.84 | 0.53 | 0.53 |
| 206.63 | -0.39 | -0.39 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 340.39 | 3.94 | 3.94 |
| 187.16 | 0.84 | 0.84 |
| 296.84 | 2.85 | 2.85 |
| 311.86 | 4.55 | 4.55 |
| 273.74 | 1.62 | 1.62 |
| 445.45 | 0.48 | 0.48 |
| 153.61 | -0.22 | -0.22 |
| 1505.11 | ||
| 276.12 | 0.82 | 0.82 |
| 172.19 | 0.80 | 0.80 |
| 339.65 | 3.22 | 3.22 |
| 321.23 | 1.73 | 1.73 |
| 281.02 | -0.43 | -0.43 |
| 168.15 | 1.22 | 1.22 |
| 429.93 | 4.51 | 4.51 |
| 381.29 | 0.94 | 0.94 |
| 466.48 | 0.42 | 0.42 |
| 295.85 | 3.17 | 3.17 |
| 514.53 | -0.14 | -0.14 |
| 422.36 | 3.93 | 3.93 |
| 390.91 | 2.65 | 2.65 |
| 766.59 | 7.73 | 7.73 |
| 183.21 | 0.48 | 0.48 |
| 336.56 | 7.30 | 7.30 |
| 234.61 | 2.01 | 2.01 |
| 519.42 | 4.40 | 4.40 |
| 316.57 | 3.41 | 3.41 |
| 189.64 | 0.38 | 0.38 |
| 282.47 | 6.11 | 6.11 |
| 213.67 | 4.04 | 4.04 |
| 268.23 | 0.97 | 0.97 |
| 392.47 | 1.90 | 1.90 |
| 223.63 | 0.23 | 0.23 |
| 220.25 | 1.29 | 1.29 |
| 598.56 | -1.20 | -1.20 |
| 517.41 | -0.14 | -0.14 |
| 366.74 | 3.93 | 3.93 |
| 198.10 | 0.30 | 0.30 |
| 426.30 | 3.09 | 3.09 |
| 300.05 | ||
| 694.37 | 2.49 | 2.49 |
| 786.36 | ||
| 203.67 | 0.90 | 0.90 |
| 564.57 | 5.96 | 5.96 |
| 424.33 | 1.56 | 1.56 |
| 184.07 | -0.09 | -0.09 |
| 520.60 | 1.13 | 1.13 |
| 554.54 | -1.89 | -1.89 |
| 538.70 | 5.67 | 5.67 |
| 616.84 | 5.75 | 5.75 |
| 548.59 |