Basic Information
ID: ALA1614287
Type: Binding
Description: PUBCHEM_BIOASSAY: uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1826, AID2127, AID2141]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614287
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.39 | 0.72 | 0.72 |
| 284.22 | 1.57 | 1.57 |
| 239.23 | 1.75 | 1.75 |
| 379.42 | 2.73 | 2.73 |
| 355.42 | 4.72 | 4.72 |
| 482.49 | 5.55 | 5.55 |
| 296.33 | 2.53 | 2.53 |
| 448.94 | 5.09 | 5.09 |
| 264.69 | 2.66 | 2.66 |
| 380.85 | 2.61 | 2.61 |
| 334.38 | 3.60 | 3.60 |
| 448.99 | 5.24 | 5.24 |
| 452.54 | 4.36 | 4.36 |
| 488.57 | 5.37 | 5.37 |
| 533.67 | 6.30 | 6.30 |
| 292.38 | 1.31 | 1.31 |
| 341.19 | 0.19 | 0.19 |
| 514.61 | 5.39 | 5.39 |
| 429.33 | 4.97 | 4.97 |
| 357.36 | 4.63 | 4.63 |
| 296.28 | 3.09 | 3.09 |
| 397.44 | 3.74 | 3.74 |
| 260.25 | 1.47 | 1.47 |
| 368.39 | 2.76 | 2.76 |
| 282.34 | 2.21 | 2.21 |
| 500.51 | 3.87 | 3.87 |
| 391.86 | 5.87 | 5.87 |
| 237.31 | 3.62 | 3.62 |
| 380.30 | 3.74 | 3.74 |
| 290.37 | 3.40 | 3.40 |
| 180.21 | 1.40 | 1.40 |
| 338.34 | 3.76 | 3.76 |
| 435.84 | 4.76 | 4.76 |
| 318.79 | 3.99 | 3.99 |
| 397.48 | 2.56 | 2.56 |
| 375.04 | 4.67 | 4.67 |
| 485.34 | 5.17 | 5.17 |
| 321.80 | 3.08 | 3.08 |
| 373.41 | 3.80 | 3.80 |
| 332.43 | 3.61 | 3.61 |
| 470.48 | 4.86 | 4.86 |
| 414.53 | 4.25 | 4.25 |
| 336.44 | 2.55 | 2.55 |
| 456.50 | 3.78 | 3.78 |
| 441.56 | 4.28 | 4.28 |
| 515.69 | 4.55 | 4.55 |
| 356.33 | 2.27 | 2.27 |
| 384.50 | 3.89 | 3.89 |
| 530.44 | 5.32 | 5.32 |
| 425.55 | 3.59 | 3.59 |
| 283.28 | 2.55 | 2.55 |
| 372.55 | 5.02 | 5.02 |
| 546.67 | 5.72 | 5.72 |
| 534.66 | 5.33 | 5.33 |
| 487.54 | 2.95 | 2.95 |
| 361.18 | 4.49 | 4.49 |
| 458.28 | 5.05 | 5.05 |
| 485.50 | 3.80 | 3.80 |
| 292.77 | 3.03 | 3.03 |
| 292.37 | 3.54 | 3.54 |
| 254.75 | 2.79 | 2.79 |
| 506.63 | 5.30 | 5.30 |
| 506.67 | 4.35 | 4.35 |
| 518.57 | 3.71 | 3.71 |
| 400.91 | 2.86 | 2.86 |
| 213.28 | 3.31 | 3.31 |
| 493.61 | 4.86 | 4.86 |
| 568.93 | 6.24 | 6.24 |
| 479.63 | 4.68 | 4.68 |
| 283.24 | 1.59 | 1.59 |
| 380.47 | 1.88 | 1.88 |
| 408.42 | 4.65 | 4.65 |
| 412.49 | 2.88 | 2.88 |
| 425.28 | 4.16 | 4.16 |
| 263.30 | 2.58 | 2.58 |
| 380.88 | 5.84 | 5.84 |
| 243.31 | 3.40 | 3.40 |
| 235.33 | 2.10 | 2.10 |
| 357.43 | 4.00 | 4.00 |
| 407.46 | 3.10 | 3.10 |
| 365.29 | 5.23 | 5.23 |
| 281.40 | 2.77 | 2.77 |
| 363.37 | 3.40 | 3.40 |
| 453.45 | 5.79 | 5.79 |
| 488.01 | 3.54 | 3.54 |
| 353.45 | 4.48 | 4.48 |
| 301.30 | 2.30 | 2.30 |
| 383.54 | 4.15 | 4.15 |
| 331.38 | 3.60 | 3.60 |
| 345.40 | 4.51 | 4.51 |
| 421.88 | 4.15 | 4.15 |
| 328.76 | 3.67 | 3.67 |
| 333.37 | 2.75 | 2.75 |
| 359.81 | 3.44 | 3.44 |
| 411.47 | 3.93 | 3.93 |
| 463.32 | 3.90 | 3.90 |
| 363.44 | 2.99 | 2.99 |
| 318.42 | 4.23 | 4.23 |
| 507.59 | 4.05 | 4.05 |
| 298.39 | 2.18 | 2.18 |
| 507.03 | 6.71 | 6.71 |
| 260.30 | 3.25 | 3.25 |
| 429.23 | 5.46 | 5.46 |
| 357.88 | 3.49 | 3.49 |
| 283.35 | 4.38 | 4.38 |
| 485.54 | 4.19 | 4.19 |
| 534.66 | 5.33 | 5.33 |
| 316.20 | 3.40 | 3.40 |
| 310.31 | 2.33 | 2.33 |
| 595.60 | 7.49 | 7.49 |
| 432.29 | 5.49 | 5.49 |
| 365.41 | 3.03 | 3.03 |
| 454.55 | 3.50 | 3.50 |
| 391.90 | 4.46 | 4.46 |
| 407.47 | 2.27 | 2.27 |
| 474.65 | 4.23 | 4.23 |
| 384.39 | 2.39 | 2.39 |
| 388.49 | 1.81 | 1.81 |
| 317.42 | 4.30 | 4.30 |
| 446.51 | 2.73 | 2.73 |
| 383.40 | 4.92 | 4.92 |
| 321.33 | 3.00 | 3.00 |
| 332.41 | 0.14 | 0.14 |
| 363.40 | 1.06 | 1.06 |
| 293.33 | 2.25 | 2.25 |
| 257.76 | 1.72 | 1.72 |
| 479.58 | 3.36 | 3.36 |
| 421.43 | 2.39 | 2.39 |
| 385.38 | 4.45 | 4.45 |
| 359.38 | 2.30 | 2.30 |
| 288.30 | 4.27 | 4.27 |
| 337.45 | 4.09 | 4.09 |
| 518.62 | 4.71 | 4.71 |
| 512.97 | 2.92 | 2.92 |
| 464.33 | 3.82 | 3.82 |
| 318.38 | 4.06 | 4.06 |
| 332.40 | 4.26 | 4.26 |
| 368.39 | 3.87 | 3.87 |
| 267.34 | 2.17 | 2.17 |
| 292.31 | 2.68 | 2.68 |
| 485.52 | 4.01 | 4.01 |
| 303.36 | 4.72 | 4.72 |
| 304.35 | 3.48 | 3.48 |
| 518.82 | 3.52 | 3.52 |
| 382.06 | 3.98 | 3.98 |
| 423.47 | 5.51 | 5.51 |
| 261.32 | 3.49 | 3.49 |
| 287.77 | 5.01 | 5.01 |
| 410.93 | 3.87 | 3.87 |
| 395.48 | 1.83 | 1.83 |
| 441.47 | 1.90 | 1.90 |
| 344.53 | 4.31 | 4.31 |