Basic Information
ID: ALA1614309
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3). (Class of assay: confirmatory) [Related pubchem assays: 1526, 1424, 1448 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614309
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.29 | 0.71 | 0.71 |
| 275.37 | 3.13 | 3.13 |
| 236.11 | 0.42 | 0.42 |
| 413.89 | 4.71 | 4.71 |
| 388.49 | 2.90 | 2.90 |
| 397.99 | 4.84 | 4.84 |
| 360.86 | 2.13 | 2.13 |
| 376.41 | 1.43 | 1.43 |
| 307.27 | 3.56 | 3.56 |
| 400.54 | 4.09 | 4.09 |
| 508.62 | 2.82 | 2.82 |
| 374.24 | 2.05 | 2.05 |
| 298.36 | 2.47 | 2.47 |
| 319.43 | 3.19 | 3.19 |
| 373.66 | 3.25 | 3.25 |
| 351.47 | 5.08 | 5.08 |
| 319.85 | 3.47 | 3.47 |
| 440.48 | 2.62 | 2.62 |
| 460.05 | 4.59 | 4.59 |
| 358.35 | 1.71 | 1.71 |
| 317.41 | 3.44 | 3.44 |
| 472.03 | 2.72 | 2.72 |
| 337.44 | 4.77 | 4.77 |
| 402.04 | 3.41 | 3.41 |
| 356.29 | 4.39 | 4.39 |
| 390.51 | 3.87 | 3.87 |
| 383.47 | 3.50 | 3.50 |
| 378.45 | 5.15 | 5.15 |
| 320.41 | 4.55 | 4.55 |
| 336.37 | 2.74 | 2.74 |
| 473.62 | 4.44 | 4.44 |
| 450.54 | 4.86 | 4.86 |
| 289.43 | 4.14 | 4.14 |
| 320.39 | 4.20 | 4.20 |
| 289.40 | 3.26 | 3.26 |
| 371.50 | 4.78 | 4.78 |
| 334.42 | 3.62 | 3.62 |
| 464.93 | 4.14 | 4.14 |
| 340.43 | 5.35 | 5.35 |
| 491.68 | 3.32 | 3.32 |
| 461.59 | 3.51 | 3.51 |
| 333.45 | 3.41 | 3.41 |
| 491.22 | 5.90 | 5.90 |
| 285.39 | 3.50 | 3.50 |
| 420.49 | 3.44 | 3.44 |
| 383.85 | 3.03 | 3.03 |
| 459.61 | 4.10 | 4.10 |
| 451.35 | 4.16 | 4.16 |
| 483.64 | 5.06 | 5.06 |
| 502.42 | 5.28 | 5.28 |
| 338.65 | 3.28 | 3.28 |
| 484.96 | 2.42 | 2.42 |
| 316.21 | 3.82 | 3.82 |
| 316.43 | 2.51 | 2.51 |
| 379.44 | 4.06 | 4.06 |
| 281.42 | 3.23 | 3.23 |
| 311.45 | 3.35 | 3.35 |
| 378.49 | 3.79 | 3.79 |
| 285.12 | 0.58 | 0.58 |
| 338.26 | 1.92 | 1.92 |
| 356.90 | 4.19 | 4.19 |
| 457.02 | 3.96 | 3.96 |
| 358.87 | 3.04 | 3.04 |
| 323.42 | 4.46 | 4.46 |
| 458.57 | 3.57 | 3.57 |
| 311.43 | 2.61 | 2.61 |
| 440.47 | 4.44 | 4.44 |
| 446.55 | 3.25 | 3.25 |
| 486.64 | 2.94 | 2.94 |
| 331.44 | 3.18 | 3.18 |
| 371.46 | 3.95 | 3.95 |
| 414.45 | 3.96 | 3.96 |
| 303.81 | 2.91 | 2.91 |
| 351.49 | 5.10 | 5.10 |
| 404.53 | 4.18 | 4.18 |
| 322.26 | 3.87 | 3.87 |
| 489.60 | 4.28 | 4.28 |
| 284.81 | 3.17 | 3.17 |
| 289.40 | 3.40 | 3.40 |
| 344.82 | 3.77 | 3.77 |
| 255.36 | 3.76 | 3.76 |
| 474.58 | 3.44 | 3.44 |
| 297.42 | 2.88 | 2.88 |
| 298.36 | 2.55 | 2.55 |
| 446.53 | 3.58 | 3.58 |
| 436.25 | 4.00 | 4.00 |
| 402.49 | 2.95 | 2.95 |
| 283.39 | 2.57 | 2.57 |
| 337.49 | 2.16 | 2.16 |
| 309.41 | 4.09 | 4.09 |
| 311.45 | 3.27 | 3.27 |
| 438.57 | 3.09 | 3.09 |
| 333.41 | 2.85 | 2.85 |
| 383.43 | 2.60 | 2.60 |
| 294.36 | 2.59 | 2.59 |
| 365.26 | 4.01 | 4.01 |
| 479.88 | 3.44 | 3.44 |
| 285.39 | 3.25 | 3.25 |
| 416.52 | 3.34 | 3.34 |
| 410.56 | 5.21 | 5.21 |
| 468.60 | 2.32 | 2.32 |
| 443.89 | 5.57 | 5.57 |
| 484.62 | 3.99 | 3.99 |
| 359.48 | 3.49 | 3.49 |
| 347.50 | 4.03 | 4.03 |
| 507.68 | 3.40 | 3.40 |
| 378.33 | 2.85 | 2.85 |
| 340.56 | 3.43 | 3.43 |
| 392.39 | 1.29 | 1.29 |
| 297.42 | 2.92 | 2.92 |
| 360.41 | 3.51 | 3.51 |
| 406.42 | 1.60 | 1.60 |
| 386.52 | 3.51 | 3.51 |
| 323.83 | 3.40 | 3.40 |
| 459.46 | 4.19 | 4.19 |
| 401.56 | 4.30 | 4.30 |
| 357.91 | 2.50 | 2.50 |
| 468.67 | 4.05 | 4.05 |
| 498.63 | 4.32 | 4.32 |
| 408.52 | 3.85 | 3.85 |
| 478.57 | 2.93 | 2.93 |
| 333.45 | 3.80 | 3.80 |
| 298.36 | 2.32 | 2.32 |
| 449.53 | 4.96 | 4.96 |
| 481.00 | 4.28 | 4.28 |
| 347.48 | 4.18 | 4.18 |
| 450.63 | 3.86 | 3.86 |
| 517.39 | 3.25 | 3.25 |
| 467.86 | 5.42 | 5.42 |
| 326.40 | 2.85 | 2.85 |
| 256.30 | 2.45 | 2.45 |
| 448.54 | 3.53 | 3.53 |
| 275.37 | 3.01 | 3.01 |
| 358.89 | 2.26 | 2.26 |
| 349.44 | 3.72 | 3.72 |
| 408.31 | 4.35 | 4.35 |
| 342.42 | 4.92 | 4.92 |
| 393.19 | 5.08 | 5.08 |
| 496.99 | 3.98 | 3.98 |
| 406.26 | 3.89 | 3.89 |
| 301.38 | 2.79 | 2.79 |
| 419.55 | 5.67 | 5.67 |
| 325.45 | 3.99 | 3.99 |
| 288.40 | 4.23 | 4.23 |
| 298.36 | 2.32 | 2.32 |
| 409.53 | 6.22 | 6.22 |
| 322.46 | 3.54 | 3.54 |
| 471.70 | 4.02 | 4.02 |
| 324.23 | 3.22 | 3.22 |
| 399.47 | 3.22 | 3.22 |
| 445.48 | 2.63 | 2.63 |
| 421.44 | 5.65 | 5.65 |
| 416.57 | 3.86 | 3.86 |
| 389.45 | 3.78 | 3.78 |
| 516.66 | 5.00 | 5.00 |
| 405.52 | 5.37 | 5.37 |
| 304.42 | 3.24 | 3.24 |
| 395.89 | 2.82 | 2.82 |
| 412.58 | 5.72 | 5.72 |
| 323.83 | 3.40 | 3.40 |
| 444.44 | 2.18 | 2.18 |
| 512.59 | 4.48 | 4.48 |
| 327.41 | 2.23 | 2.23 |
| 418.52 | 2.91 | 2.91 |
| 348.26 | 3.02 | 3.02 |
| 388.49 | 2.36 | 2.36 |
| 488.99 | 3.91 | 3.91 |
| 324.27 | 2.93 | 2.93 |
| 392.52 | 4.04 | 4.04 |
| 369.34 | 4.82 | 4.82 |
| 433.47 | 4.40 | 4.40 |
| 348.26 | 2.88 | 2.88 |
| 350.46 | 3.20 | 3.20 |
| 500.78 | 3.07 | 3.07 |
| 518.47 | 5.90 | 5.90 |
| 278.38 | 2.51 | 2.51 |
| 375.49 | 2.77 | 2.77 |
| 301.46 | 2.80 | 2.80 |
| 452.60 | 3.39 | 3.39 |
| 265.38 | 2.56 | 2.56 |
| 430.98 | 5.24 | 5.24 |
| 326.42 | 3.28 | 3.28 |
| 386.93 | 3.31 | 3.31 |
| 388.49 | 3.76 | 3.76 |
| 398.53 | 4.63 | 4.63 |
| 319.38 | 2.86 | 2.86 |
| 407.09 | 3.05 | 3.05 |
| 520.61 | 4.56 | 4.56 |