Basic Information
ID: ALA1614311
Type: Binding
Description: PUBCHEM_BIOASSAY: TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1. (Class of assay: confirmatory) [Related pubchem assays: 432 ]
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1614311
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.55 | 4.20 | 4.20 |
| 252.27 | 2.64 | 2.64 |
| 276.25 | 2.54 | 2.54 |
| 319.58 | 2.88 | 2.88 |
| 494.76 | 3.86 | 3.86 |
| 476.79 | 4.65 | 4.65 |
| 305.77 | 1.34 | 1.34 |
| 342.23 | 1.87 | 1.87 |
| 374.65 | 2.56 | 2.56 |
| 374.65 | 2.56 | 2.56 |
| 374.65 | 2.56 | 2.56 |
| 374.65 | 2.56 | 2.56 |
| 388.68 | 2.87 | 2.87 |
| 340.21 | 1.91 | 1.91 |
| 340.21 | 1.91 | 1.91 |
| 319.79 | 1.57 | 1.57 |
| 350.76 | 1.17 | 1.17 |
| 345.61 | 3.41 | 3.41 |
| 359.64 | 3.80 | 3.80 |
| 381.65 | 4.11 | 4.11 |
| 361.61 | 2.65 | 2.65 |
| 388.68 | 2.95 | 2.95 |
| 374.66 | 2.61 | 2.61 |
| 374.66 | 2.61 | 2.61 |
| 388.64 | 2.14 | 2.14 |
| 416.74 | 3.73 | 3.73 |
| 404.68 | 1.93 | 1.93 |
| 448.73 | 1.94 | 1.94 |
| 436.73 | 4.14 | 4.14 |
| 466.75 | 4.15 | 4.15 |
| 466.75 | 4.15 | 4.15 |
| 466.75 | 4.15 | 4.15 |
| 450.75 | 4.45 | 4.45 |
| 504.72 | 5.16 | 5.16 |
| 450.75 | 4.13 | 4.13 |
| 310.40 | 2.14 | 2.14 |
| 334.38 | 2.17 | 2.17 |
| 435.33 | 3.88 | 3.88 |
| 393.85 | 3.04 | 3.04 |
| 271.26 | 1.87 | 1.87 |
| 327.17 | 2.00 | 2.00 |
| 287.33 | 3.19 | 3.19 |
| 364.79 | 1.56 | 1.56 |
| 275.67 | 2.52 | 2.52 |
| 393.87 | 0.95 | 0.95 |
| 273.30 | 2.88 | 2.88 |
| 389.31 | 3.06 | 3.06 |
| 361.61 | 2.65 | 2.65 |
| 326.57 | 3.68 | 3.68 |
| 424.84 | 0.54 | 0.54 |
| 494.81 | 3.12 | 3.12 |
| 374.66 | 2.56 | 2.56 |
| 496.49 | 5.38 | 5.38 |
| 375.64 | 2.96 | 2.96 |
| 310.95 | 3.56 | 3.56 |
| 327.17 | 2.00 | 2.00 |
| 400.38 | 2.60 | 2.60 |
| 416.74 | 3.78 | 3.78 |
| 449.36 | 3.08 | 3.08 |
| 339.29 | 3.33 | 3.33 |
| 319.32 | 3.67 | 3.67 |
| 423.75 | 3.72 | 3.72 |
| 295.68 | 1.48 | 1.48 |
| 276.51 | 2.90 | 2.90 |
| 470.87 | 2.46 | 2.46 |
| 349.83 | 2.70 | 2.70 |
| 277.49 | 2.30 | 2.30 |
| 267.29 | 2.04 | 2.04 |
| 322.16 | 3.04 | 3.04 |
| 257.68 | 2.38 | 2.38 |
| 388.68 | 3.00 | 3.00 |
| 357.46 | 3.13 | 3.13 |
| 310.95 | 3.56 | 3.56 |
| 561.30 | 6.38 | 6.38 |
| 337.72 | 1.25 | 1.25 |
| 341.24 | 3.36 | 3.36 |
| 362.33 | 2.58 | 2.58 |
| 385.61 | 4.57 | 4.57 |
| 376.63 | 4.84 | 4.84 |
| 307.74 | 3.53 | 3.53 |
| 409.87 | 0.65 | 0.65 |
| 480.78 | 4.54 | 4.54 |
| 354.76 | 2.64 | 2.64 |
| 403.70 | 1.89 | 1.89 |
| 464.64 | 4.42 | 4.42 |
| 324.98 | 3.86 | 3.86 |
| 291.29 | 3.02 | 3.02 |
| 380.79 | 0.53 | 0.53 |
| 505.62 | 5.45 | 5.45 |
| 240.21 | 1.21 | 1.21 |
| 344.37 | 3.74 | 3.74 |
| 159.19 | 1.40 | 1.40 |
| 561.68 | 2.04 | 2.04 |
| 438.87 | 2.93 | 2.93 |
| 359.41 | 2.39 | 2.39 |
| 415.52 | 3.68 | 3.68 |
| 271.36 | 3.09 | 3.09 |
| 337.31 | 3.81 | 3.81 |
| 236.27 | 3.68 | 3.68 |
| 310.38 | 3.21 | 3.21 |
| 277.49 | 2.30 | 2.30 |
| 403.49 | 2.84 | 2.84 |
| 308.73 | 2.93 | 2.93 |
| 361.61 | 2.65 | 2.65 |
| 349.82 | 0.93 | 0.93 |
| 392.33 | 2.64 | 2.64 |
| 248.31 | 1.86 | 1.86 |
| 338.44 | 3.32 | 3.32 |
| 388.21 | 3.90 | 3.90 |
| 352.34 | 3.72 | 3.72 |
| 271.71 | 2.69 | 2.69 |
| 341.20 | 1.31 | 1.31 |
| 374.34 | 2.50 | 2.50 |
| 443.98 | 3.45 | 3.45 |
| 332.30 | 2.57 | 2.57 |
| 438.70 | 2.93 | 2.93 |
| 288.70 | 1.78 | 1.78 |
| 253.27 | 1.73 | 1.73 |
| 485.20 | 5.10 | 5.10 |
| 259.40 | 3.25 | 3.25 |
| 293.12 | 2.43 | 2.43 |
| 310.06 | 3.27 | 3.27 |
| 450.75 | 4.53 | 4.53 |
| 223.24 | 1.72 | 1.72 |
| 384.27 | 3.35 | 3.35 |
| 471.17 | 4.79 | 4.79 |
| 374.66 | 2.61 | 2.61 |
| 343.18 | 3.58 | 3.58 |
| 342.19 | 4.18 | 4.18 |
| 381.77 | 3.51 | 3.51 |
| 340.39 | 4.59 | 4.59 |
| 404.46 | 3.93 | 3.93 |
| 390.30 | 4.89 | 4.89 |
| 487.56 | 4.70 | 4.70 |
| 377.40 | 2.53 | 2.53 |
| 250.30 | 3.99 | 3.99 |
| 350.76 | 1.21 | 1.21 |
| 310.95 | 3.56 | 3.56 |
| 258.67 | 1.77 | 1.77 |
| 241.23 | 1.86 | 1.86 |
| 212.25 | 3.00 | 3.00 |
| 237.27 | 2.03 | 2.03 |
| 337.72 | 1.25 | 1.25 |
| 454.72 | 4.28 | 4.28 |
| 464.78 | 4.76 | 4.76 |
| 454.72 | 4.28 | 4.28 |
| 276.51 | 2.90 | 2.90 |
| 310.95 | 3.56 | 3.56 |
| 316.15 | 4.45 | 4.45 |
| 328.16 | 1.39 | 1.39 |
| 257.25 | 1.66 | 1.66 |
| 380.43 | 3.28 | 3.28 |
| 368.42 | 3.55 | 3.55 |
| 361.61 | 2.65 | 2.65 |
| 450.75 | 4.45 | 4.45 |
| 355.23 | 1.70 | 1.70 |
| 321.77 | 3.84 | 3.84 |
| 337.31 | 2.73 | 2.73 |
| 326.78 | 3.74 | 3.74 |
| 471.17 | 4.79 | 4.79 |
| 484.37 | 6.29 | 6.29 |
| 367.62 | 4.43 | 4.43 |
| 325.73 | 3.67 | 3.67 |
| 310.95 | 3.56 | 3.56 |
| 319.32 | 2.59 | 2.59 |
| 292.13 | 3.03 | 3.03 |
| 333.35 | 2.90 | 2.90 |
| 415.28 | 0.69 | 0.69 |
| 230.25 | -0.02 | -0.02 |
| 349.60 | 2.55 | 2.55 |
| 361.61 | 2.65 | 2.65 |
| 204.27 | 2.30 | 2.30 |
| 287.06 | 2.16 | 2.16 |
| 257.33 | 3.00 | 3.00 |
| 313.45 | 3.49 | 3.49 |