Basic Information
ID: ALA1614314
Type: Functional
Description: PUBCHEM_BIOASSAY: uHTS Fluorescence assay for the identification of cytotoxic compounds among compounds active in NOD2 cell inhibition assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1579, AID2260, AID2334, AID2335, AID2475, AID2503, AID2799, AID2800]
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1614314
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.41 | 4.34 | 4.34 |
| 312.22 | 4.67 | 4.67 |
| 322.42 | 3.50 | 3.50 |
| 284.34 | 3.04 | 3.04 |
| 319.19 | 4.45 | 4.45 |
| 488.41 | 5.17 | 5.17 |
| 447.02 | 3.21 | 3.21 |
| 476.54 | 6.83 | 6.83 |
| 361.23 | 4.47 | 4.47 |
| 320.22 | 2.94 | 2.94 |
| 531.43 | 3.78 | 3.78 |
| 432.98 | 3.34 | 3.34 |
| 374.47 | 4.90 | 4.90 |
| 416.55 | 5.00 | 5.00 |
| 507.57 | 4.31 | 4.31 |
| 402.28 | 5.66 | 5.66 |
| 440.40 | 3.26 | 3.26 |
| 307.35 | 3.80 | 3.80 |
| 321.81 | 4.17 | 4.17 |
| 347.46 | 4.28 | 4.28 |
| 385.44 | 3.87 | 3.87 |
| 461.61 | 3.45 | 3.45 |
| 531.46 | 5.37 | 5.37 |
| 386.50 | 3.51 | 3.51 |
| 406.44 | 3.58 | 3.58 |
| 395.44 | 4.29 | 4.29 |
| 524.40 | 4.64 | 4.64 |
| 518.59 | 5.46 | 5.46 |
| 323.81 | 2.81 | 2.81 |
| 316.98 | 3.77 | 3.77 |
| 400.28 | 3.81 | 3.81 |
| 382.49 | 4.43 | 4.43 |
| 420.44 | 5.18 | 5.18 |
| 374.36 | 3.83 | 3.83 |
| 232.20 | 1.11 | 1.11 |
| 437.48 | 4.48 | 4.48 |
| 277.33 | 4.97 | 4.97 |
| 337.41 | 3.68 | 3.68 |
| 412.53 | 5.24 | 5.24 |
| 510.63 | 6.23 | 6.23 |
| 400.52 | 4.63 | 4.63 |
| 351.79 | 4.58 | 4.58 |
| 292.34 | 4.44 | 4.44 |
| 337.34 | 3.07 | 3.07 |
| 442.61 | 3.70 | 3.70 |
| 492.35 | 5.15 | 5.15 |
| 393.49 | 4.79 | 4.79 |
| 317.27 | 5.37 | 5.37 |
| 338.37 | 2.55 | 2.55 |
| 405.47 | 3.85 | 3.85 |
| 369.27 | 4.19 | 4.19 |
| 342.17 | 3.00 | 3.00 |
| 383.54 | 4.29 | 4.29 |
| 345.66 | 3.93 | 3.93 |
| 389.50 | 3.35 | 3.35 |
| 416.86 | 4.50 | 4.50 |
| 337.43 | 3.59 | 3.59 |
| 392.50 | 3.73 | 3.73 |
| 429.47 | 5.05 | 5.05 |
| 335.81 | 4.23 | 4.23 |
| 331.37 | 3.39 | 3.39 |
| 422.34 | 4.66 | 4.66 |
| 459.75 | 3.38 | 3.38 |
| 393.19 | 4.26 | 4.26 |
| 420.45 | 3.70 | 3.70 |
| 455.56 | 4.55 | 4.55 |
| 290.75 | 3.37 | 3.37 |
| 279.30 | 4.36 | 4.36 |
| 485.43 | 5.70 | 5.70 |
| 293.78 | 2.80 | 2.80 |
| 253.37 | 5.09 | 5.09 |
| 494.57 | 3.34 | 3.34 |
| 382.46 | 5.66 | 5.66 |
| 505.10 | 4.69 | 4.69 |
| 321.43 | 3.89 | 3.89 |
| 308.79 | 3.57 | 3.57 |
| 329.36 | 3.16 | 3.16 |
| 457.56 | 3.46 | 3.46 |
| 311.77 | 3.72 | 3.72 |
| 354.79 | 3.82 | 3.82 |
| 234.21 | 2.61 | 2.61 |
| 252.27 | 3.47 | 3.47 |
| 486.94 | 3.44 | 3.44 |
| 268.27 | 3.17 | 3.17 |
| 474.59 | 4.29 | 4.29 |
| 419.87 | 3.80 | 3.80 |
| 448.59 | 4.79 | 4.79 |
| 458.90 | 4.48 | 4.48 |
| 429.50 | 2.80 | 2.80 |
| 259.27 | 1.89 | 1.89 |
| 385.51 | 3.72 | 3.72 |
| 403.50 | 4.58 | 4.58 |
| 387.89 | 4.97 | 4.97 |
| 472.36 | 5.07 | 5.07 |
| 394.86 | 4.20 | 4.20 |
| 404.30 | 3.79 | 3.79 |
| 426.56 | 2.50 | 2.50 |
| 373.48 | 3.29 | 3.29 |
| 374.40 | 3.86 | 3.86 |
| 357.39 | 3.84 | 3.84 |
| 413.43 | 1.88 | 1.88 |
| 305.72 | 4.17 | 4.17 |
| 413.86 | 4.45 | 4.45 |
| 688.63 | 5.48 | 5.48 |
| 472.98 | 4.67 | 4.67 |
| 410.45 | 3.53 | 3.53 |
| 544.61 | 3.17 | 3.17 |
| 335.20 | 3.48 | 3.48 |
| 324.21 | 4.20 | 4.20 |
| 248.67 | 2.31 | 2.31 |
| 354.36 | 3.21 | 3.21 |
| 404.47 | 3.54 | 3.54 |
| 486.98 | 3.57 | 3.57 |
| 442.50 | 3.38 | 3.38 |
| 424.51 | 4.44 | 4.44 |
| 421.88 | 4.24 | 4.24 |
| 400.46 | 4.04 | 4.04 |
| 387.44 | 1.39 | 1.39 |
| 316.41 | 3.93 | 3.93 |
| 346.41 | 5.21 | 5.21 |
| 316.36 | -0.14 | -0.14 |
| 384.28 | 4.11 | 4.11 |
| 311.77 | 4.77 | 4.77 |
| 378.39 | 2.84 | 2.84 |
| 357.40 | 3.32 | 3.32 |
| 330.43 | 4.23 | 4.23 |
| 334.38 | 3.73 | 3.73 |
| 333.42 | 4.32 | 4.32 |
| 595.03 | ||
| 387.33 | 2.38 | 2.38 |
| 494.98 | 3.00 | 3.00 |
| 278.29 | 2.13 | 2.13 |
| 372.22 | 4.59 | 4.59 |
| 400.91 | 2.86 | 2.86 |
| 450.52 | 4.09 | 4.09 |
| 338.32 | 2.90 | 2.90 |
| 387.48 | 3.64 | 3.64 |
| 344.46 | 3.63 | 3.63 |
| 361.40 | 3.19 | 3.19 |
| 380.45 | 4.93 | 4.93 |
| 447.39 | 5.07 | 5.07 |
| 339.40 | 3.75 | 3.75 |
| 462.98 | 3.75 | 3.75 |
| 352.80 | 4.75 | 4.75 |
| 398.55 | 5.15 | 5.15 |
| 359.48 | 4.14 | 4.14 |
| 267.30 | 4.03 | 4.03 |
| 376.43 | 4.50 | 4.50 |
| 243.26 | 1.13 | 1.13 |
| 415.52 | 5.88 | 5.88 |
| 404.70 | 4.46 | 4.46 |
| 393.42 | 4.89 | 4.89 |
| 502.02 | 5.05 | 5.05 |
| 357.79 | 4.47 | 4.47 |
| 461.52 | 5.70 | 5.70 |
| 462.55 | 4.42 | 4.42 |
| 390.39 | 4.54 | 4.54 |
| 308.38 | 4.75 | 4.75 |
| 492.62 | 5.57 | 5.57 |
| 173.21 | 2.56 | 2.56 |
| 445.52 | 3.93 | 3.93 |
| 289.40 | 2.65 | 2.65 |
| 442.63 | 4.40 | 4.40 |
| 376.41 | 5.15 | 5.15 |
| 471.56 | 2.84 | 2.84 |
| 338.48 | 4.08 | 4.08 |
| 335.27 | 4.87 | 4.87 |
| 340.40 | 4.61 | 4.61 |
| 355.26 | 2.94 | 2.94 |
| 297.36 | 2.86 | 2.86 |
| 542.08 | 5.19 | 5.19 |
| 322.39 | 3.91 | 3.91 |
| 374.40 | 3.47 | 3.47 |
| 445.36 | 3.12 | 3.12 |
| 372.43 | 3.70 | 3.70 |
| 419.87 | 3.80 | 3.80 |
| 276.72 | 2.92 | 2.92 |
| 377.40 | 4.71 | 4.71 |
| 349.46 | 2.72 | 2.72 |
| 401.49 | 3.71 | 3.71 |
| 426.50 | 4.86 | 4.86 |
| 493.99 | 3.50 | 3.50 |
| 366.45 | 5.02 | 5.02 |
| 560.68 | 3.07 | 3.07 |
| 456.59 | 3.84 | 3.84 |
| 459.98 | 3.78 | 3.78 |
| 458.77 | 3.92 | 3.92 |
| 323.36 | 3.79 | 3.79 |
| 355.42 | 3.78 | 3.78 |
| 426.49 | 3.53 | 3.53 |
| 372.38 | 3.44 | 3.44 |
| 391.45 | 3.88 | 3.88 |
| 434.59 | 3.24 | 3.24 |
| 303.81 | 4.11 | 4.11 |
| 330.84 | 2.43 | 2.43 |
| 337.40 | 0.52 | 0.52 |
| 531.66 | 4.13 | 4.13 |
| 388.45 | 2.57 | 2.57 |
| 340.81 | 4.51 | 4.51 |
| 386.25 | 4.89 | 4.89 |
| 294.31 | 3.02 | 3.02 |
| 350.45 | 5.32 | 5.32 |
| 490.54 | 3.74 | 3.74 |
| 479.60 | 3.44 | 3.44 |
| 462.37 | 3.01 | 3.01 |
| 544.61 | 3.17 | 3.17 |
| 344.46 | 3.63 | 3.63 |
| 301.80 | 4.80 | 4.80 |
| 332.45 | 4.02 | 4.02 |
| 318.37 | 3.80 | 3.80 |
| 467.41 | 3.58 | 3.58 |
| 494.67 | 5.74 | 5.74 |
| 437.55 | 4.68 | 4.68 |
| 420.47 | 5.35 | 5.35 |
| 282.30 | 3.86 | 3.86 |
| 264.26 | 1.82 | 1.82 |
| 549.74 | 4.42 | 4.42 |
| 350.29 | 3.64 | 3.64 |
| 438.44 | 4.04 | 4.04 |
| 275.78 | 3.77 | 3.77 |
| 253.33 | 3.31 | 3.31 |
| 494.04 | 4.12 | 4.12 |
| 333.43 | 4.04 | 4.04 |
| 336.35 | 1.92 | 1.92 |
| 436.94 | 4.53 | 4.53 |
| 367.45 | 3.26 | 3.26 |
| 339.37 | 2.55 | 2.55 |
| 322.32 | 2.50 | 2.50 |
| 400.53 | 4.26 | 4.26 |
| 372.42 | 5.04 | 5.04 |
| 497.57 | 2.92 | 2.92 |
| 426.49 | 4.03 | 4.03 |
| 372.38 | 3.87 | 3.87 |
| 356.45 | 3.58 | 3.58 |
| 282.30 | 1.89 | 1.89 |
| 402.36 | 3.81 | 3.81 |
| 279.30 | 4.36 | 4.36 |
| 355.35 | 3.31 | 3.31 |
| 394.86 | 4.13 | 4.13 |
| 371.42 | 3.78 | 3.78 |
| 358.83 | 5.64 | 5.64 |
| 335.81 | 3.24 | 3.24 |
| 438.87 | 4.62 | 4.62 |
| 322.36 | 3.18 | 3.18 |
| 367.39 | 3.02 | 3.02 |
| 444.56 | 5.49 | 5.49 |
| 279.34 | 3.72 | 3.72 |
| 401.56 | 4.22 | 4.22 |
| 343.60 | 3.66 | 3.66 |
| 313.79 | 4.09 | 4.09 |
| 330.32 | 3.27 | 3.27 |
| 436.49 | 2.76 | 2.76 |
| 456.54 | 5.21 | 5.21 |
| 480.61 | 2.27 | 2.27 |
| 458.31 | 4.56 | 4.56 |
| 406.44 | 3.98 | 3.98 |
| 352.44 | 2.25 | 2.25 |
| 331.39 | 3.59 | 3.59 |
| 481.60 | 3.69 | 3.69 |
| 375.45 | 4.45 | 4.45 |
| 432.55 | 4.38 | 4.38 |
| 499.98 | 4.04 | 4.04 |
| 309.37 | 4.25 | 4.25 |
| 266.77 | 1.88 | 1.88 |
| 380.92 | 3.20 | 3.20 |
| 471.99 | 5.34 | 5.34 |
| 447.54 | 3.35 | 3.35 |
| 311.77 | 3.72 | 3.72 |
| 531.66 | 4.13 | 4.13 |
| 534.16 | 5.27 | 5.27 |
| 307.35 | 4.22 | 4.22 |
| 517.63 | 3.82 | 3.82 |
| 381.28 | 5.32 | 5.32 |
| 341.79 | 4.78 | 4.78 |
| 401.36 | 3.45 | 3.45 |
| 361.40 | 4.27 | 4.27 |
| 274.32 | 2.24 | 2.24 |
| 420.30 | 4.09 | 4.09 |
| 496.05 | 6.28 | 6.28 |
| 489.60 | 5.04 | 5.04 |
| 304.15 | 3.60 | 3.60 |
| 342.40 | 3.61 | 3.61 |
| 393.47 | 4.31 | 4.31 |
| 486.64 | 2.55 | 2.55 |
| 381.21 | 5.13 | 5.13 |
| 354.84 | 3.31 | 3.31 |
| 457.53 | 3.98 | 3.98 |
| 452.58 | 4.14 | 4.14 |
| 431.92 | 4.55 | 4.55 |
| 294.76 | 3.26 | 3.26 |
| 380.45 | 3.72 | 3.72 |
| 256.91 | 3.57 | 3.57 |
| 468.55 | 5.20 | 5.20 |
| 421.55 | 4.82 | 4.82 |
| 266.17 | -0.08 | -0.08 |
| 264.67 | 1.99 | 1.99 |
| 265.19 | 0.64 | 0.64 |
| 375.26 | 4.28 | 4.28 |
| 362.39 | 4.66 | 4.66 |
| 406.47 | 3.81 | 3.81 |
| 299.24 | 2.70 | 2.70 |
| 338.34 | 2.38 | 2.38 |
| 342.40 | 4.08 | 4.08 |
| 292.68 | 2.79 | 2.79 |
| 291.31 | 2.70 | 2.70 |
| 325.37 | 2.57 | 2.57 |
| 259.70 | 2.50 | 2.50 |
| 436.49 | 4.05 | 4.05 |
| 351.37 | 2.82 | 2.82 |
| 351.37 | 2.94 | 2.94 |
| 374.42 | 3.41 | 3.41 |
| 415.42 | 4.09 | 4.09 |
| 334.17 | 2.70 | 2.70 |
| 369.36 | 2.96 | 2.96 |
| 358.15 | 1.69 | 1.69 |
| 534.00 | 3.56 | 3.56 |
| 477.45 | 3.77 | 3.77 |
| 343.22 | 4.27 | 4.27 |
| 257.27 | 2.37 | 2.37 |
| 385.49 | 4.17 | 4.17 |
| 381.34 | 3.33 | 3.33 |