Basic Information
ID: ALA1614321
Type: Binding
Description: PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide. (Class of assay: confirmatory) [Related pubchem assays: 2090 (Summary AID.), 2057 (Screening assay (MCL1 inhibitors).), 2168 (Screening assay (MCL1 inhibitors).)]
Organism: Homo sapiens
Cell type: myeloid
Activity Charts
Bioactivity
Activity Types for Assay ALA1614321
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.32 | 2.21 | 2.21 |
| 299.31 | -1.69 | -1.69 |
| 300.27 | 2.59 | 2.59 |
| 302.24 | 1.99 | 1.99 |
| 348.31 | 2.69 | 2.69 |
| 296.41 | 4.01 | 4.01 |
| 222.27 | 2.23 | 2.23 |
| 337.43 | 1.19 | 1.19 |
| 341.32 | 2.60 | 2.60 |
| 355.83 | 4.41 | 4.41 |
| 343.34 | 3.92 | 3.92 |
| 371.82 | 4.50 | 4.50 |
| 385.45 | 3.36 | 3.36 |
| 447.55 | 4.45 | 4.45 |
| 476.55 | 5.02 | 5.02 |
| 242.23 | 2.71 | 2.71 |
| 472.50 | 3.33 | 3.33 |
| 383.23 | 3.57 | 3.57 |
| 442.90 | 3.72 | 3.72 |
| 344.44 | 2.96 | 2.96 |
| 332.15 | 4.26 | 4.26 |
| 378.21 | 4.07 | 4.07 |
| 286.29 | 2.20 | 2.20 |
| 381.46 | 3.90 | 3.90 |
| 276.30 | 3.89 | 3.89 |
| 343.39 | 4.76 | 4.76 |
| 295.37 | 3.27 | 3.27 |
| 350.43 | 2.70 | 2.70 |
| 493.39 | 4.68 | 4.68 |
| 304.40 | 3.25 | 3.25 |
| 448.55 | 4.34 | 4.34 |
| 407.34 | 3.11 | 3.11 |
| 406.19 | 2.82 | 2.82 |
| 252.72 | 3.91 | 3.91 |
| 460.52 | 4.22 | 4.22 |
| 467.55 | 3.01 | 3.01 |
| 344.33 | 5.52 | 5.52 |
| 493.94 | 0.03 | 0.03 |
| 417.45 | 3.75 | 3.75 |
| 367.34 | 1.86 | 1.86 |
| 323.33 | 2.69 | 2.69 |
| 388.40 | 2.34 | 2.34 |
| 425.47 | 2.83 | 2.83 |
| 273.29 | 2.44 | 2.44 |
| 365.42 | 2.16 | 2.16 |
| 315.42 | 3.37 | 3.37 |
| 428.56 | 1.90 | 1.90 |
| 495.00 | 5.97 | 5.97 |
| 359.40 | 3.86 | 3.86 |
| 392.39 | 3.38 | 3.38 |
| 316.36 | 1.85 | 1.85 |
| 291.31 | 3.45 | 3.45 |
| 347.40 | 2.40 | 2.40 |
| 295.34 | 2.99 | 2.99 |
| 418.47 | 1.37 | 1.37 |
| 464.89 | 4.63 | 4.63 |
| 506.49 | 4.36 | 4.36 |
| 367.37 | 1.82 | 1.82 |
| 375.48 | 3.39 | 3.39 |
| 259.29 | 3.11 | 3.11 |
| 335.39 | 4.68 | 4.68 |
| 299.25 | 3.12 | 3.12 |
| 409.53 | 1.90 | 1.90 |
| 349.30 | -0.46 | -0.46 |
| 347.42 | 3.46 | 3.46 |
| 335.39 | 4.51 | 4.51 |
| 317.19 | 1.42 | 1.42 |
| 324.43 | 2.53 | 2.53 |
| 322.75 | 3.09 | 3.09 |
| 435.87 | 4.65 | 4.65 |
| 390.42 | 1.85 | 1.85 |
| 304.30 | 4.02 | 4.02 |
| 424.45 | 3.14 | 3.14 |
| 414.49 | 3.92 | 3.92 |
| 474.49 | 4.20 | 4.20 |
| 404.43 | 2.52 | 2.52 |
| 280.76 | 5.03 | 5.03 |
| 264.23 | 2.69 | 2.69 |
| 361.45 | 3.80 | 3.80 |
| 372.70 | 3.40 | 3.40 |
| 426.84 | 4.92 | 4.92 |
| 459.46 | 3.23 | 3.23 |
| 339.78 | 3.68 | 3.68 |
| 487.33 | 4.43 | 4.43 |
| 464.91 | 4.11 | 4.11 |
| 365.41 | 3.03 | 3.03 |
| 432.72 | 3.91 | 3.91 |
| 338.32 | 2.91 | 2.91 |
| 314.33 | 2.31 | 2.31 |
| 455.54 | 3.15 | 3.15 |
| 361.42 | 3.05 | 3.05 |
| 316.74 | 3.83 | 3.83 |
| 368.42 | 2.91 | 2.91 |
| 455.54 | 3.30 | 3.30 |
| 582.48 | 2.89 | 2.89 |
| 395.41 | 4.01 | 4.01 |
| 282.34 | 2.64 | 2.64 |
| 308.39 | 2.95 | 2.95 |
| 330.14 | 4.26 | 4.26 |
| 429.42 | 3.92 | 3.92 |
| 409.49 | 2.77 | 2.77 |
| 406.19 | 2.81 | 2.81 |
| 513.54 | 4.16 | 4.16 |
| 359.36 | 4.40 | 4.40 |
| 246.22 | 1.45 | 1.45 |
| 396.83 | 5.31 | 5.31 |
| 357.39 | 2.90 | 2.90 |
| 404.25 | 2.73 | 2.73 |
| 359.43 | 3.84 | 3.84 |
| 371.37 | 3.29 | 3.29 |
| 355.35 | 1.38 | 1.38 |
| 534.40 | 2.95 | 2.95 |
| 372.38 | 3.35 | 3.35 |
| 414.87 | 3.30 | 3.30 |
| 452.26 | 4.45 | 4.45 |
| 384.23 | 1.75 | 1.75 |
| 409.45 | 5.31 | 5.31 |
| 331.24 | 1.37 | 1.37 |
| 345.38 | 2.42 | 2.42 |
| 449.49 | 0.91 | 0.91 |
| 347.37 | 3.10 | 3.10 |
| 423.86 | 4.16 | 4.16 |
| 297.41 | 2.83 | 2.83 |
| 311.30 | 1.70 | 1.70 |
| 313.27 | 1.91 | 1.91 |
| 401.20 | 1.19 | 1.19 |
| 345.45 | 4.06 | 4.06 |
| 469.54 | 1.94 | 1.94 |