Basic Information
ID: ALA1614328
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for BLMA Inhibitors: ADP Fluorescence Polarization Displacement Assay. (Class of assay: confirmatory) [Related pubchem assays: 2528 (qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM)), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 2585 (qHTS Confirmation Assay for Inhibitors of Bloom's syndrome helicase (BLM)), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))]
Activity Charts
Bioactivity
Activity Types for Assay ALA1614328
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.19 | 1.31 | 1.31 |
| 211.22 | 0.44 | 0.44 |
| 302.37 | 3.57 | 3.57 |
| 444.49 | -0.14 | -0.14 |
| 153.18 | 0.60 | 0.60 |
| 242.27 | 2.75 | 2.75 |
| 305.76 | 2.73 | 2.73 |
| 183.21 | 0.48 | 0.48 |
| 183.21 | 0.35 | 0.35 |
| 1297.30 | ||
| 504.45 | 5.08 | 5.08 |
| 183.21 | 0.48 | 0.48 |
| 284.22 | 1.57 | 1.57 |
| 174.16 | 1.33 | 1.33 |
| 518.56 | 6.38 | 6.38 |
| 197.19 | 0.05 | 0.05 |
| 353.47 | 1.94 | 1.94 |
| 497.50 | 1.02 | 1.02 |
| 314.25 | 2.82 | 2.82 |
| 368.48 | 4.88 | 4.88 |
| 213.19 | -0.24 | -0.24 |
| 456.68 | 6.17 | 6.17 |
| 214.27 | 2.54 | 2.54 |
| 169.18 | 0.30 | 0.30 |
| 197.19 | 0.05 | 0.05 |
| 415.50 | -0.32 | -0.32 |
| 332.31 | 3.97 | 3.97 |
| 527.53 | 1.03 | 1.03 |
| 290.27 | 1.55 | 1.55 |
| 197.19 | 0.05 | 0.05 |
| 169.18 | 0.09 | 0.09 |
| 328.35 | 2.72 | 2.72 |
| 210.30 | 2.98 | 2.98 |
| 452.46 | 2.38 | 2.38 |
| 205.64 | 0.30 | 0.30 |
| 223.23 | 0.54 | 0.54 |
| 285.39 | 4.93 | 4.93 |
| 327.43 | 5.95 | 5.95 |
| 160.18 | 1.11 | 1.11 |
| 376.37 | -1.72 | -1.72 |
| 513.50 | 0.73 | 0.73 |
| 241.25 | 2.05 | 2.05 |
| 372.86 | 3.67 | 3.67 |
| 472.89 | 5.97 | 5.97 |
| 392.50 | 2.39 | 2.39 |
| 340.39 | 3.94 | 3.94 |
| 385.38 | 3.96 | 3.96 |
| 183.21 | 0.48 | 0.48 |
| 305.76 | 2.73 | 2.73 |
| 310.39 | 4.45 | 4.45 |
| 339.44 | 1.92 | 1.92 |
| 973.67 | 9.00 | 9.00 |
| 246.22 | 1.93 | 1.93 |
| 386.67 | 2.73 | 2.73 |
| 454.55 | 2.40 | 2.40 |
| 497.51 | 3.48 | 3.48 |
| 436.49 | 4.28 | 4.28 |
| 251.33 | 3.06 | 3.06 |
| 456.55 | 2.39 | 2.39 |
| 449.52 | 2.30 | 2.30 |
| 444.47 | 3.08 | 3.08 |
| 325.32 | 2.12 | 2.12 |
| 391.42 | 4.45 | 4.45 |
| 437.50 | 3.21 | 3.21 |
| 179.17 | -0.75 | -0.75 |
| 862.75 | -1.10 | -1.10 |
| 376.36 | 3.66 | 3.66 |
| 372.43 | 3.09 | 3.09 |
| 183.21 | 0.48 | 0.48 |
| 450.61 | 6.62 | 6.62 |
| 440.52 | 2.92 | 2.92 |
| 282.25 | 2.75 | 2.75 |
| 334.38 | 3.73 | 3.73 |
| 228.25 | 2.34 | 2.34 |
| 490.54 | 5.25 | 5.25 |
| 281.36 | 2.37 | 2.37 |
| 267.24 | 3.33 | 3.33 |
| 367.36 | 5.22 | 5.22 |
| 299.38 | 2.90 | 2.90 |
| 528.66 | 5.74 | 5.74 |
| 365.46 | 2.25 | 2.25 |
| 397.39 | 4.08 | 4.08 |
| 474.57 | 4.84 | 4.84 |
| 300.31 | 3.43 | 3.43 |
| 444.45 | 3.02 | 3.02 |
| 398.38 | 3.89 | 3.89 |
| 539.71 | 4.12 | 4.12 |
| 304.40 | 3.25 | 3.25 |
| 449.92 | 5.64 | 5.64 |
| 430.55 | 3.52 | 3.52 |
| 339.15 | 1.91 | 1.91 |
| 224.33 | 3.87 | 3.87 |
| 534.96 | 0.84 | 0.84 |
| 275.37 | 3.73 | 3.73 |
| 270.25 | 2.74 | 2.74 |
| 341.39 | 2.62 | 2.62 |
| 606.07 | 2.16 | 2.16 |
| 337.38 | 3.20 | 3.20 |
| 409.51 | 4.08 | 4.08 |
| 460.52 | 4.22 | 4.22 |
| 385.46 | 5.74 | 5.74 |
| 142.54 | 0.82 | 0.82 |
| 407.43 | 2.96 | 2.96 |
| 378.39 | 3.65 | 3.65 |
| 354.52 | 5.36 | 5.36 |
| 458.45 | 3.57 | 3.57 |
| 467.58 | 3.98 | 3.98 |
| 425.47 | 4.06 | 4.06 |
| 394.46 | 3.24 | 3.24 |
| 479.63 | 5.94 | 5.94 |
| 402.36 | 1.87 | 1.87 |
| 458.92 | 5.05 | 5.05 |
| 340.43 | 3.99 | 3.99 |
| 956.68 | 0.02 | 0.02 |
| 315.37 | 5.11 | 5.11 |
| 513.65 | 2.57 | 2.57 |
| 318.13 | 3.96 | 3.96 |
| 270.25 | 0.24 | 0.24 |
| 496.47 | -1.24 | -1.24 |
| 327.45 | 4.87 | 4.87 |
| 357.42 | 2.78 | 2.78 |
| 436.42 | 1.96 | 1.96 |
| 581.67 | 1.99 | 1.99 |
| 305.32 | -0.93 | -0.93 |
| 424.53 | 2.77 | 2.77 |
| 493.36 | 4.03 | 4.03 |
| 412.47 | 3.99 | 3.99 |
| 353.42 | 4.02 | 4.02 |
| 416.50 | 2.29 | 2.29 |
| 517.41 | -0.14 | -0.14 |
| 287.36 | 2.97 | 2.97 |
| 453.54 | 2.80 | 2.80 |
| 404.90 | 4.69 | 4.69 |
| 326.38 | 3.41 | 3.41 |
| 449.63 | 3.72 | 3.72 |
| 366.37 | 3.42 | 3.42 |
| 336.35 | 3.06 | 3.06 |
| 444.47 | 1.69 | 1.69 |
| 464.57 | 3.53 | 3.53 |
| 278.31 | 3.39 | 3.39 |
| 252.36 | 2.13 | 2.13 |
| 402.47 | 2.31 | 2.31 |
| 225.29 | 2.71 | 2.71 |
| 474.59 | 3.25 | 3.25 |
| 529.40 | 0.01 | 0.01 |
| 447.52 | 3.44 | 3.44 |
| 398.50 | 6.38 | 6.38 |
| 302.33 | 2.35 | 2.35 |
| 490.99 | 4.06 | 4.06 |
| 453.41 | 2.51 | 2.51 |
| 442.42 | 0.56 | 0.56 |
| 462.51 | 2.47 | 2.47 |
| 383.45 | 4.24 | 4.24 |
| 335.39 | 4.68 | 4.68 |
| 868.71 | 4.18 | 4.18 |
| 387.44 | 2.34 | 2.34 |
| 211.22 | 0.44 | 0.44 |
| 223.23 | 0.54 | 0.54 |
| 243.31 | 3.40 | 3.40 |
| 471.58 | 2.65 | 2.65 |
| 323.35 | 3.52 | 3.52 |
| 237.31 | 3.43 | 3.43 |
| 324.41 | 3.88 | 3.88 |
| 436.55 | 4.34 | 4.34 |
| 533.63 | 4.60 | 4.60 |
| 317.73 | 3.06 | 3.06 |
| 315.42 | 3.99 | 3.99 |
| 420.47 | 2.62 | 2.62 |
| 426.37 | 4.17 | 4.17 |
| 374.49 | 3.13 | 3.13 |
| 412.31 | 3.61 | 3.61 |
| 311.36 | 0.84 | 0.84 |
| 315.41 | 3.75 | 3.75 |
| 366.51 | 4.71 | 4.71 |
| 358.40 | 4.86 | 4.86 |
| 508.39 | -1.53 | -1.53 |
| 496.90 | -1.24 | -1.24 |
| 199.30 | 1.96 | 1.96 |
| 332.36 | 1.95 | 1.95 |
| 301.39 | 3.36 | 3.36 |
| 543.67 | 4.31 | 4.31 |
| 477.50 | 4.43 | 4.43 |
| 478.89 | -0.44 | -0.44 |
| 310.31 | 2.41 | 2.41 |
| 485.60 | 4.53 | 4.53 |
| 432.35 | 5.04 | 5.04 |
| 430.53 | 3.44 | 3.44 |
| 357.44 | 2.85 | 2.85 |
| 475.29 | 4.42 | 4.42 |
| 352.41 | 4.51 | 4.51 |
| 332.81 | 3.40 | 3.40 |
| 353.41 | 3.09 | 3.09 |
| 404.46 | 3.93 | 3.93 |
| 358.85 | 4.53 | 4.53 |
| 378.38 | 1.22 | 1.22 |
| 403.46 | 1.89 | 1.89 |
| 322.36 | 4.12 | 4.12 |
| 381.50 | 2.88 | 2.88 |
| 336.39 | 4.43 | 4.43 |
| 543.53 | 0.00 | 0.00 |
| 428.39 | 1.41 | 1.41 |
| 442.38 | 2.53 | 2.53 |
| 544.61 | 2.92 | 2.92 |
| 296.37 | 3.44 | 3.44 |
| 548.56 | 3.84 | 3.84 |
| 312.44 | 3.20 | 3.20 |
| 352.46 | 4.12 | 4.12 |
| 338.27 | 1.99 | 1.99 |
| 254.31 | 3.52 | 3.52 |
| 353.47 | 3.97 | 3.97 |
| 445.48 | 3.05 | 3.05 |
| 479.61 | 2.16 | 2.16 |
| 470.52 | 3.14 | 3.14 |
| 527.53 | 1.03 | 1.03 |
| 458.59 | 4.59 | 4.59 |
| 478.51 | 3.34 | 3.34 |
| 262.27 | 3.59 | 3.59 |
| 396.36 | 1.93 | 1.93 |
| 475.51 | 2.32 | 2.32 |
| 338.46 | 2.84 | 2.84 |
| 352.39 | 3.52 | 3.52 |
| 438.51 | 3.35 | 3.35 |
| 543.53 | 0.00 | 0.00 |
| 439.49 | 4.45 | 4.45 |
| 804.70 | ||
| 464.60 | 2.83 | 2.83 |
| 421.53 | 3.51 | 3.51 |
| 378.45 | 1.38 | 1.38 |
| 410.43 | 3.81 | 3.81 |
| 327.34 | 2.97 | 2.97 |
| 267.33 | 1.75 | 1.75 |
| 314.18 | 2.66 | 2.66 |
| 267.29 | 2.65 | 2.65 |
| 383.40 | 3.53 | 3.53 |
| 416.48 | 3.60 | 3.60 |
| 321.26 | 3.77 | 3.77 |
| 424.43 | 3.92 | 3.92 |
| 359.43 | 3.05 | 3.05 |
| 504.01 | 4.83 | 4.83 |
| 349.44 | 3.39 | 3.39 |
| 284.27 | 1.62 | 1.62 |
| 372.45 | 4.09 | 4.09 |
| 514.03 | 2.15 | 2.15 |
| 421.45 | 3.25 | 3.25 |
| 442.42 | -0.44 | -0.44 |
| 329.31 | 3.22 | 3.22 |
| 682.15 | ||
| 305.72 | 1.24 | 1.24 |
| 348.38 | 2.59 | 2.59 |
| 233.30 | 1.68 | 1.68 |
| 434.43 | 4.43 | 4.43 |
| 769.90 | 5.31 | 5.31 |
| 368.42 | 1.86 | 1.86 |
| 316.74 | 3.83 | 3.83 |
| 490.47 | 3.12 | 3.12 |
| 285.33 | 3.36 | 3.36 |
| 465.55 | 4.51 | 4.51 |
| 280.30 | 2.26 | 2.26 |
| 497.60 | 4.07 | 4.07 |
| 477.59 | 3.09 | 3.09 |
| 405.52 | 4.34 | 4.34 |
| 446.58 | 5.01 | 5.01 |
| 390.46 | 3.19 | 3.19 |
| 229.28 | 3.45 | 3.45 |
| 343.80 | 3.86 | 3.86 |
| 346.35 | 2.85 | 2.85 |
| 279.39 | 3.95 | 3.95 |
| 148.17 | 0.73 | 0.73 |
| 695.05 | ||
| 370.82 | 4.02 | 4.02 |
| 277.37 | 3.73 | 3.73 |
| 695.05 | ||
| 427.57 | 1.41 | 1.41 |
| 387.40 | 3.26 | 3.26 |
| 314.42 | 4.18 | 4.18 |
| 750.66 | ||
| 221.26 | 4.00 | 4.00 |
| 622.54 | 1.91 | 1.91 |
| 409.53 | 4.30 | 4.30 |
| 288.35 | 3.08 | 3.08 |
| 506.97 | 5.43 | 5.43 |
| 359.36 | 4.40 | 4.40 |
| 359.36 | 4.40 | 4.40 |
| 300.27 | 1.08 | 1.08 |
| 305.83 | 3.69 | 3.69 |
| 284.31 | 2.78 | 2.78 |
| 229.24 | 1.48 | 1.48 |
| 566.69 | 2.47 | 2.47 |
| 404.25 | 2.73 | 2.73 |
| 355.35 | 1.38 | 1.38 |
| 362.39 | 4.66 | 4.66 |
| 478.89 | -0.44 | -0.44 |
| 924.09 | 0.71 | 0.71 |
| 298.25 | 1.43 | 1.43 |
| 337.36 | 1.24 | 1.24 |
| 566.69 | 2.87 | 2.87 |
| 419.47 | 2.80 | 2.80 |
| 397.53 | 4.02 | 4.02 |
| 278.29 | 2.51 | 2.51 |
| 393.83 | 4.06 | 4.06 |
| 340.50 | 3.53 | 3.53 |
| 285.23 | 2.90 | 2.90 |
| 320.76 | 3.21 | 3.21 |
| 429.50 | 4.70 | 4.70 |
| 233.31 | 2.86 | 2.86 |
| 426.47 | 2.34 | 2.34 |