Basic Information
ID: ALA1614359
Type: Binding
Description: PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this dose response confirmation assay.)]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614359
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 207.25 | 1.55 | 1.55 |
| 211.22 | 0.44 | 0.44 |
| 281.36 | 2.84 | 2.84 |
| 356.06 | 5.86 | 5.86 |
| 368.52 | 5.11 | 5.11 |
| 309.20 | 3.25 | 3.25 |
| 279.32 | 1.93 | 1.93 |
| 241.25 | 2.64 | 2.64 |
| 423.43 | 2.73 | 2.73 |
| 328.35 | 2.72 | 2.72 |
| 382.40 | 2.93 | 2.93 |
| 207.25 | 2.53 | 2.53 |
| 246.26 | 3.17 | 3.17 |
| 176.18 | 1.57 | 1.57 |
| 285.33 | 3.36 | 3.36 |
| 444.54 | 5.86 | 5.86 |
| 258.32 | 2.07 | 2.07 |
| 184.24 | 2.66 | 2.66 |
| 336.26 | 2.00 | 2.00 |
| 454.55 | 2.76 | 2.76 |
| 390.46 | 4.35 | 4.35 |
| 449.53 | 3.77 | 3.77 |
| 278.27 | 1.07 | 1.07 |
| 228.29 | 3.78 | 3.78 |
| 432.53 | 2.92 | 2.92 |
| 424.39 | 3.05 | 3.05 |
| 346.41 | 2.27 | 2.27 |
| 264.35 | 2.26 | 2.26 |
| 319.38 | 2.91 | 2.91 |
| 416.43 | 3.98 | 3.98 |
| 403.43 | 3.01 | 3.01 |
| 426.56 | 4.63 | 4.63 |
| 385.45 | 3.36 | 3.36 |
| 364.43 | 3.42 | 3.42 |
| 437.50 | 3.21 | 3.21 |
| 357.44 | 2.79 | 2.79 |
| 313.15 | 1.62 | 1.62 |
| 499.49 | 4.34 | 4.34 |
| 360.46 | 2.98 | 2.98 |
| 463.49 | 3.79 | 3.79 |
| 399.41 | 3.86 | 3.86 |
| 381.43 | 3.78 | 3.78 |
| 424.49 | 4.01 | 4.01 |
| 313.35 | 3.56 | 3.56 |
| 379.37 | 2.33 | 2.33 |
| 345.20 | 3.31 | 3.31 |
| 360.44 | 1.65 | 1.65 |
| 496.49 | 5.38 | 5.38 |
| 396.52 | 3.12 | 3.12 |
| 270.36 | 3.06 | 3.06 |
| 274.30 | 2.93 | 2.93 |
| 402.44 | 1.77 | 1.77 |
| 261.32 | 1.31 | 1.31 |
| 365.48 | 3.01 | 3.01 |
| 444.53 | 5.75 | 5.75 |
| 286.29 | 2.20 | 2.20 |
| 343.81 | 3.72 | 3.72 |
| 430.49 | 3.39 | 3.39 |
| 281.32 | 3.49 | 3.49 |
| 360.48 | 2.96 | 2.96 |
| 366.49 | 2.60 | 2.60 |
| 347.37 | 2.55 | 2.55 |
| 381.46 | 3.90 | 3.90 |
| 186.26 | 2.59 | 2.59 |
| 316.45 | 4.17 | 4.17 |
| 436.52 | 2.03 | 2.03 |
| 306.27 | 0.67 | 0.67 |
| 393.38 | 1.93 | 1.93 |
| 492.53 | 4.47 | 4.47 |
| 249.31 | 2.28 | 2.28 |
| 354.34 | 1.30 | 1.30 |
| 283.26 | 2.09 | 2.09 |
| 206.20 | 1.44 | 1.44 |
| 374.45 | 2.52 | 2.52 |
| 266.77 | 4.13 | 4.13 |
| 242.23 | 1.33 | 1.33 |
| 439.48 | 2.89 | 2.89 |
| 359.48 | 4.18 | 4.18 |
| 295.43 | 3.51 | 3.51 |
| 376.41 | 3.28 | 3.28 |
| 294.31 | 3.13 | 3.13 |
| 266.68 | 2.90 | 2.90 |
| 265.34 | 1.24 | 1.24 |
| 327.30 | 0.98 | 0.98 |
| 218.28 | 2.32 | 2.32 |
| 310.38 | 1.01 | 1.01 |
| 388.47 | 4.99 | 4.99 |
| 463.52 | 1.73 | 1.73 |
| 252.72 | 3.91 | 3.91 |
| 347.39 | 2.56 | 2.56 |
| 454.50 | 2.50 | 2.50 |
| 325.39 | 2.66 | 2.66 |
| 320.35 | 3.81 | 3.81 |
| 466.53 | 5.12 | 5.12 |
| 282.67 | 4.05 | 4.05 |
| 264.31 | 1.22 | 1.22 |
| 467.57 | 4.09 | 4.09 |
| 251.33 | 4.21 | 4.21 |
| 336.82 | 2.60 | 2.60 |
| 404.22 | 1.68 | 1.68 |
| 480.48 | 2.23 | 2.23 |
| 381.43 | 3.59 | 3.59 |
| 430.35 | 3.98 | 3.98 |
| 230.29 | 3.07 | 3.07 |
| 342.36 | 2.49 | 2.49 |
| 314.35 | 1.10 | 1.10 |
| 400.31 | 4.31 | 4.31 |
| 311.17 | 3.00 | 3.00 |
| 393.47 | 1.96 | 1.96 |
| 339.80 | 2.56 | 2.56 |
| 267.24 | 2.53 | 2.53 |
| 365.44 | 1.56 | 1.56 |
| 459.52 | 1.14 | 1.14 |
| 415.45 | 3.92 | 3.92 |
| 441.60 | 2.73 | 2.73 |
| 326.41 | 3.29 | 3.29 |
| 353.38 | 4.53 | 4.53 |
| 390.35 | 3.41 | 3.41 |
| 318.13 | 3.96 | 3.96 |
| 298.40 | 3.51 | 3.51 |
| 388.54 | 3.24 | 3.24 |
| 431.91 | 4.84 | 4.84 |
| 431.49 | 2.48 | 2.48 |
| 542.39 | 5.34 | 5.34 |
| 335.45 | 3.66 | 3.66 |
| 275.33 | 3.18 | 3.18 |
| 408.21 | 4.39 | 4.39 |
| 438.87 | 4.39 | 4.39 |
| 400.46 | 4.64 | 4.64 |
| 394.41 | -0.81 | -0.81 |
| 297.77 | 2.08 | 2.08 |
| 263.38 | 3.53 | 3.53 |
| 361.46 | 3.34 | 3.34 |
| 402.68 | 6.74 | 6.74 |
| 316.79 | 2.38 | 2.38 |
| 273.32 | 2.66 | 2.66 |
| 431.52 | 3.86 | 3.86 |
| 252.31 | 1.50 | 1.50 |
| 431.48 | 3.79 | 3.79 |
| 487.64 | 5.57 | 5.57 |
| 332.36 | 4.33 | 4.33 |
| 315.42 | 3.37 | 3.37 |
| 352.43 | 3.11 | 3.11 |
| 357.46 | 3.46 | 3.46 |
| 368.46 | 2.68 | 2.68 |
| 292.29 | 3.09 | 3.09 |
| 263.28 | 0.35 | 0.35 |
| 298.80 | 2.21 | 2.21 |
| 416.32 | 4.59 | 4.59 |
| 460.46 | 4.05 | 4.05 |
| 232.26 | 3.25 | 3.25 |
| 454.35 | 3.65 | 3.65 |
| 283.28 | 2.55 | 2.55 |
| 345.37 | 1.29 | 1.29 |
| 354.32 | 1.90 | 1.90 |
| 354.43 | 4.81 | 4.81 |
| 411.44 | 3.74 | 3.74 |
| 337.42 | 2.65 | 2.65 |
| 432.30 | 3.45 | 3.45 |
| 386.79 | 2.65 | 2.65 |
| 294.31 | 3.53 | 3.53 |
| 352.42 | 3.98 | 3.98 |
| 345.45 | 3.38 | 3.38 |
| 446.56 | 4.31 | 4.31 |
| 288.36 | 3.10 | 3.10 |
| 403.51 | 3.65 | 3.65 |
| 243.31 | 2.95 | 2.95 |
| 303.43 | 2.92 | 2.92 |
| 360.46 | 3.59 | 3.59 |
| 299.36 | 3.37 | 3.37 |
| 328.43 | 2.72 | 2.72 |
| 334.34 | 2.90 | 2.90 |
| 240.31 | 3.41 | 3.41 |
| 346.34 | 4.53 | 4.53 |
| 256.30 | 2.98 | 2.98 |
| 478.53 | 5.22 | 5.22 |
| 391.45 | 4.92 | 4.92 |
| 378.52 | 3.35 | 3.35 |
| 296.42 | 3.35 | 3.35 |
| 342.32 | 1.08 | 1.08 |
| 326.38 | 3.33 | 3.33 |
| 434.45 | 2.38 | 2.38 |
| 433.46 | 1.21 | 1.21 |
| 408.59 | 4.52 | 4.52 |
| 454.62 | 1.86 | 1.86 |
| 399.45 | 4.58 | 4.58 |
| 451.48 | 3.34 | 3.34 |
| 381.48 | 4.13 | 4.13 |
| 419.50 | 2.98 | 2.98 |
| 325.37 | 0.88 | 0.88 |
| 446.48 | 4.17 | 4.17 |
| 428.51 | 1.89 | 1.89 |
| 353.45 | 4.48 | 4.48 |
| 312.28 | 2.02 | 2.02 |
| 311.22 | 2.79 | 2.79 |
| 265.36 | 3.02 | 3.02 |
| 417.47 | 4.57 | 4.57 |
| 345.45 | 4.18 | 4.18 |
| 314.32 | 1.81 | 1.81 |
| 375.38 | 3.01 | 3.01 |
| 304.19 | 3.38 | 3.38 |
| 338.39 | 3.18 | 3.18 |
| 261.36 | 3.14 | 3.14 |
| 270.29 | 1.95 | 1.95 |
| 417.52 | 4.17 | 4.17 |
| 443.28 | 3.53 | 3.53 |
| 290.27 | 2.21 | 2.21 |
| 199.30 | 1.96 | 1.96 |
| 388.47 | 2.83 | 2.83 |
| 366.44 | 3.85 | 3.85 |
| 293.71 | 2.41 | 2.41 |
| 366.40 | 3.28 | 3.28 |
| 499.59 | 4.33 | 4.33 |
| 343.41 | 2.54 | 2.54 |
| 326.74 | 4.16 | 4.16 |
| 368.46 | 3.80 | 3.80 |
| 401.49 | 0.84 | 0.84 |
| 365.22 | 4.14 | 4.14 |
| 327.34 | 0.38 | 0.38 |
| 311.34 | 2.52 | 2.52 |
| 430.49 | 4.43 | 4.43 |
| 322.41 | 4.80 | 4.80 |
| 252.36 | 4.14 | 4.14 |
| 443.55 | 4.12 | 4.12 |
| 265.25 | 3.15 | 3.15 |
| 223.32 | 2.47 | 2.47 |
| 258.26 | 2.71 | 2.71 |
| 452.58 | 3.93 | 3.93 |
| 302.42 | 4.16 | 4.16 |
| 324.34 | 3.99 | 3.99 |
| 299.75 | 2.05 | 2.05 |
| 201.31 | 2.08 | 2.08 |
| 349.31 | 2.59 | 2.59 |
| 375.48 | 2.85 | 2.85 |
| 221.28 | 2.85 | 2.85 |
| 281.36 | 2.96 | 2.96 |
| 358.85 | 4.53 | 4.53 |
| 265.29 | 1.81 | 1.81 |
| 271.34 | 2.83 | 2.83 |
| 405.47 | 2.54 | 2.54 |
| 445.48 | 2.89 | 2.89 |
| 408.20 | 2.17 | 2.17 |
| 256.29 | 2.34 | 2.34 |
| 375.38 | 4.81 | 4.81 |
| 536.12 | 5.73 | 5.73 |
| 297.31 | 2.65 | 2.65 |
| 395.48 | 3.76 | 3.76 |
| 370.43 | 3.51 | 3.51 |
| 336.44 | 2.56 | 2.56 |
| 459.46 | 3.23 | 3.23 |
| 497.65 | 3.96 | 3.96 |
| 269.26 | 2.70 | 2.70 |
| 312.44 | 3.20 | 3.20 |
| 294.31 | 4.32 | 4.32 |
| 445.48 | 3.05 | 3.05 |
| 285.32 | 3.59 | 3.59 |
| 410.47 | 2.81 | 2.81 |
| 480.52 | 5.12 | 5.12 |
| 514.56 | 5.98 | 5.98 |
| 254.24 | 2.48 | 2.48 |
| 246.27 | 1.04 | 1.04 |
| 285.25 | 2.02 | 2.02 |
| 294.31 | -0.39 | -0.39 |
| 259.33 | 3.51 | 3.51 |
| 349.39 | 4.19 | 4.19 |
| 463.51 | 2.80 | 2.80 |
| 359.43 | 0.69 | 0.69 |
| 243.29 | 2.34 | 2.34 |
| 314.18 | 2.66 | 2.66 |
| 303.15 | 2.01 | 2.01 |
| 320.37 | 2.99 | 2.99 |
| 310.34 | 2.32 | 2.32 |
| 352.35 | 2.72 | 2.72 |
| 400.49 | 4.58 | 4.58 |
| 369.79 | 4.10 | 4.10 |
| 282.33 | 3.04 | 3.04 |
| 387.40 | 3.22 | 3.22 |
| 424.93 | 4.23 | 4.23 |
| 281.78 | 3.23 | 3.23 |
| 397.46 | 2.71 | 2.71 |
| 432.25 | 2.23 | 2.23 |
| 308.31 | 1.29 | 1.29 |
| 377.44 | 3.65 | 3.65 |
| 313.78 | 1.71 | 1.71 |
| 396.43 | 2.67 | 2.67 |
| 311.41 | 3.73 | 3.73 |
| 290.32 | 2.55 | 2.55 |
| 412.48 | 1.44 | 1.44 |
| 412.55 | 1.71 | 1.71 |
| 407.47 | 2.25 | 2.25 |
| 438.55 | 3.52 | 3.52 |
| 349.42 | 1.54 | 1.54 |
| 365.44 | 2.64 | 2.64 |
| 323.36 | 2.30 | 2.30 |
| 360.46 | 4.36 | 4.36 |
| 406.35 | 2.73 | 2.73 |
| 311.14 | 0.96 | 0.96 |
| 364.49 | 3.10 | 3.10 |
| 500.00 | 3.04 | 3.04 |
| 287.34 | 3.19 | 3.19 |
| 349.25 | 3.85 | 3.85 |
| 316.74 | 3.83 | 3.83 |
| 350.51 | 3.41 | 3.41 |
| 321.40 | 3.23 | 3.23 |
| 156.23 | 0.20 | 0.20 |
| 314.82 | 4.21 | 4.21 |
| 279.32 | 1.49 | 1.49 |
| 293.35 | 1.72 | 1.72 |
| 232.24 | 2.12 | 2.12 |
| 253.26 | -0.60 | -0.60 |
| 327.47 | 4.16 | 4.16 |
| 399.53 | 2.07 | 2.07 |
| 285.33 | 3.36 | 3.36 |
| 347.37 | 3.36 | 3.36 |
| 310.40 | 3.09 | 3.09 |
| 274.35 | 3.14 | 3.14 |
| 280.30 | 2.26 | 2.26 |
| 333.41 | 3.35 | 3.35 |
| 324.42 | 3.92 | 3.92 |
| 314.42 | 3.11 | 3.11 |
| 243.73 | 1.83 | 1.83 |
| 310.40 | 2.49 | 2.49 |
| 348.36 | 1.91 | 1.91 |
| 304.37 | 3.41 | 3.41 |
| 256.37 | 4.42 | 4.42 |
| 418.48 | 3.95 | 3.95 |
| 470.33 | 2.78 | 2.78 |
| 343.80 | 3.86 | 3.86 |
| 279.39 | 3.95 | 3.95 |
| 277.37 | 3.73 | 3.73 |
| 354.23 | 3.40 | 3.40 |
| 423.49 | 3.15 | 3.15 |
| 347.37 | 4.36 | 4.36 |
| 288.33 | 2.33 | 2.33 |
| 259.26 | 1.75 | 1.75 |
| 352.42 | 3.57 | 3.57 |
| 353.27 | 4.24 | 4.24 |
| 295.28 | 0.48 | 0.48 |
| 296.35 | 3.22 | 3.22 |
| 209.21 | 0.90 | 0.90 |
| 391.50 | 1.78 | 1.78 |
| 300.31 | 3.18 | 3.18 |
| 308.39 | 0.37 | 0.37 |
| 217.27 | 2.69 | 2.69 |
| 371.90 | 3.40 | 3.40 |
| 398.82 | 2.04 | 2.04 |
| 416.43 | 0.99 | 0.99 |
| 366.45 | 3.67 | 3.67 |
| 278.33 | 1.51 | 1.51 |
| 288.32 | 3.18 | 3.18 |
| 394.43 | 4.27 | 4.27 |
| 275.30 | 1.65 | 1.65 |
| 379.24 | 2.33 | 2.33 |
| 250.25 | 1.47 | 1.47 |
| 225.30 | 1.78 | 1.78 |
| 235.24 | 1.13 | 1.13 |
| 317.39 | 1.20 | 1.20 |
| 250.33 | 1.25 | 1.25 |
| 324.38 | 1.63 | 1.63 |
| 254.25 | 2.50 | 2.50 |
| 413.52 | 4.39 | 4.39 |
| 554.97 | 4.69 | 4.69 |
| 355.35 | 1.38 | 1.38 |
| 316.81 | 4.28 | 4.28 |
| 330.37 | 3.21 | 3.21 |
| 439.53 | 3.30 | 3.30 |
| 388.38 | 5.44 | 5.44 |
| 309.35 | 2.27 | 2.27 |
| 335.36 | 4.06 | 4.06 |
| 345.45 | 4.06 | 4.06 |
| 452.52 | 4.97 | 4.97 |
| 388.25 | 3.03 | 3.03 |
| 309.41 | 2.40 | 2.40 |
| 298.34 | 2.69 | 2.69 |
| 373.42 | 3.10 | 3.10 |
| 465.54 | 5.10 | 5.10 |
| 229.19 | 0.01 | 0.01 |
| 364.81 | 3.77 | 3.77 |
| 214.27 | 3.10 | 3.10 |
| 323.80 | 3.00 | 3.00 |
| 346.39 | 2.19 | 2.19 |
| 314.37 | 2.44 | 2.44 |
| 319.39 | 1.78 | 1.78 |
| 366.35 | 3.81 | 3.81 |
| 349.20 | 2.74 | 2.74 |
| 303.37 | 3.76 | 3.76 |
| 359.48 | 4.37 | 4.37 |
| 489.55 | 2.59 | 2.59 |
| 255.36 | 2.73 | 2.73 |
| 324.30 | 3.07 | 3.07 |