Basic Information
ID: ALA1614405
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for APE1 Inhibitors: Confirmatory Fluorescent Dye Displacement Assay. (Class of assay: confirmatory) [Related pubchem assays: 2565 (Counterscreen for APE1 Inhibitors: qHTS Assay for Inhibitors of Endonuclease IV), 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 2572 (Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)]
Activity Charts
Bioactivity
Activity Types for Assay ALA1614405
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.22 | 1.28 | 1.28 |
| 316.26 | 2.29 | 2.29 |
| 538.46 | 5.13 | 5.13 |
| 518.47 | 4.60 | 4.60 |
| 222.27 | 2.23 | 2.23 |
| 604.73 | 6.82 | 6.82 |
| 449.53 | 3.77 | 3.77 |
| 448.38 | -0.20 | -0.20 |
| 420.40 | 4.19 | 4.19 |
| 358.40 | 3.41 | 3.41 |
| 334.38 | 3.60 | 3.60 |
| 604.70 | 6.36 | 6.36 |
| 364.43 | 3.42 | 3.42 |
| 358.38 | 1.37 | 1.37 |
| 429.46 | 4.28 | 4.28 |
| 429.46 | 4.28 | 4.28 |
| 260.25 | 1.47 | 1.47 |
| 358.40 | 4.32 | 4.32 |
| 490.54 | 5.25 | 5.25 |
| 402.44 | 1.77 | 1.77 |
| 360.37 | 4.43 | 4.43 |
| 286.29 | 2.20 | 2.20 |
| 373.43 | 1.62 | 1.62 |
| 389.44 | 2.63 | 2.63 |
| 194.22 | 1.21 | 1.21 |
| 442.57 | 4.13 | 4.13 |
| 318.13 | 3.67 | 3.67 |
| 407.81 | 3.93 | 3.93 |
| 396.41 | 4.47 | 4.47 |
| 300.31 | 3.43 | 3.43 |
| 376.25 | 2.66 | 2.66 |
| 348.79 | 4.89 | 4.89 |
| 428.94 | 2.68 | 2.68 |
| 393.42 | 4.38 | 4.38 |
| 348.45 | 3.03 | 3.03 |
| 251.17 | 1.24 | 1.24 |
| 295.43 | 3.51 | 3.51 |
| 432.50 | 1.22 | 1.22 |
| 366.40 | 1.00 | 1.00 |
| 352.42 | 1.72 | 1.72 |
| 454.50 | 2.50 | 2.50 |
| 269.21 | 2.08 | 2.08 |
| 356.33 | 2.27 | 2.27 |
| 229.28 | 2.53 | 2.53 |
| 956.68 | 0.02 | 0.02 |
| 290.27 | 1.93 | 1.93 |
| 422.85 | 3.01 | 3.01 |
| 264.31 | 2.26 | 2.26 |
| 260.32 | 1.84 | 1.84 |
| 326.31 | 1.95 | 1.95 |
| 381.24 | 4.57 | 4.57 |
| 315.42 | 3.37 | 3.37 |
| 331.17 | 3.41 | 3.41 |
| 594.52 | -1.39 | -1.39 |
| 304.37 | 2.26 | 2.26 |
| 427.57 | 2.29 | 2.29 |
| 515.56 | 6.01 | 6.01 |
| 527.62 | 6.02 | 6.02 |
| 278.31 | 3.39 | 3.39 |
| 328.35 | 2.84 | 2.84 |
| 360.33 | 3.40 | 3.40 |
| 310.38 | 4.23 | 4.23 |
| 404.49 | 1.77 | 1.77 |
| 426.43 | 4.43 | 4.43 |
| 307.37 | 3.31 | 3.31 |
| 408.42 | 4.65 | 4.65 |
| 226.28 | 3.39 | 3.39 |
| 375.48 | 3.39 | 3.39 |
| 446.37 | 3.04 | 3.04 |
| 473.60 | 1.20 | 1.20 |
| 420.47 | 2.62 | 2.62 |
| 369.38 | 1.39 | 1.39 |
| 448.38 | -0.20 | -0.20 |
| 319.36 | 3.17 | 3.17 |
| 432.51 | 4.01 | 4.01 |
| 477.50 | 4.43 | 4.43 |
| 448.49 | 5.41 | 5.41 |
| 484.64 | 3.65 | 3.65 |
| 450.83 | 4.80 | 4.80 |
| 329.40 | 3.95 | 3.95 |
| 301.39 | 4.18 | 4.18 |
| 940.68 | 1.69 | 1.69 |
| 423.43 | 5.60 | 5.60 |
| 479.00 | 4.97 | 4.97 |
| 314.25 | 1.50 | 1.50 |
| 466.83 | 3.55 | 3.55 |
| 524.60 | 4.17 | 4.17 |
| 294.31 | 4.32 | 4.32 |
| 416.43 | 4.35 | 4.35 |
| 458.59 | 4.59 | 4.59 |
| 324.79 | 2.46 | 2.46 |
| 245.28 | 2.23 | 2.23 |
| 312.35 | 3.53 | 3.53 |
| 349.35 | 4.80 | 4.80 |
| 408.80 | 3.76 | 3.76 |
| 542.59 | 3.91 | 3.91 |
| 307.14 | 2.93 | 2.93 |
| 390.42 | 1.95 | 1.95 |
| 406.47 | 4.74 | 4.74 |
| 438.51 | 2.71 | 2.71 |
| 393.36 | 1.98 | 1.98 |
| 334.41 | 3.37 | 3.37 |
| 475.53 | 4.27 | 4.27 |
| 457.30 | 2.49 | 2.49 |
| 465.60 | 1.67 | 1.67 |
| 354.32 | 0.95 | 0.95 |
| 329.31 | 3.22 | 3.22 |
| 402.45 | 5.56 | 5.56 |
| 302.38 | 3.39 | 3.39 |
| 364.49 | 3.10 | 3.10 |
| 434.52 | 4.02 | 4.02 |
| 314.27 | 2.08 | 2.08 |
| 406.47 | 4.74 | 4.74 |
| 452.47 | 3.90 | 3.90 |
| 502.59 | 3.30 | 3.30 |
| 278.17 | 0.72 | 0.72 |
| 336.39 | 3.59 | 3.59 |
| 416.41 | 5.02 | 5.02 |
| 264.28 | 3.47 | 3.47 |
| 380.45 | 4.71 | 4.71 |
| 300.36 | 3.10 | 3.10 |
| 368.33 | 0.80 | 0.80 |
| 397.46 | 3.21 | 3.21 |
| 299.31 | 1.86 | 1.86 |
| 404.25 | 2.73 | 2.73 |
| 464.43 | 1.80 | 1.80 |
| 355.35 | 1.38 | 1.38 |
| 375.41 | 2.36 | 2.36 |
| 427.37 | 1.73 | 1.73 |
| 388.40 | 3.42 | 3.42 |
| 407.09 | 3.05 | 3.05 |
| 337.34 | 2.40 | 2.40 |
| 325.28 | 0.61 | 0.61 |
| 279.32 | 1.39 | 1.39 |
| 387.40 | 3.27 | 3.27 |
| 388.25 | 3.03 | 3.03 |
| 280.74 | 4.37 | 4.37 |
| 360.43 | 2.09 | 2.09 |
| 378.41 | 0.79 | 0.79 |
| 205.18 | 0.62 | 0.62 |
| 264.27 | 2.20 | 2.20 |
| 340.41 | 3.07 | 3.07 |
| 416.55 | 4.33 | 4.33 |