Assay Report Card

Basic Information

ID: ALA1614408

Type: Functional

Description: PUBCHEM_BIOASSAY: Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2). (Class of assay: confirmatory) [Related pubchem assays: 2379 (Confirmation (NR2E3 agonists in quadruplicate)), 2759 (Dose response counterscreen (PPARg and NCOR2 interaction agonists in triplicate)), 2758 (Dose response (NR2E3 agonists in quadruplicate)), 2325 (Summary (NR2E3 agonists)), 2300 (Primary screen (NR2E3 agonists in singlicate))]

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
333.412.572.57
349.391.731.73
444.545.865.86
450.524.604.60
490.492.592.59
483.596.166.16
422.544.744.74
360.462.702.70
363.443.543.54
401.883.883.88
301.432.412.41
347.304.404.40
363.194.334.33
333.392.792.79
376.804.764.76
330.372.882.88
390.513.923.92
372.474.124.12
310.743.443.44
409.524.564.56
462.515.815.81
404.494.914.91
392.482.402.40
458.563.393.39
340.385.055.05
459.334.304.30
407.453.813.81
380.763.873.87
452.923.533.53
393.304.844.84
377.241.971.97
419.344.884.88
265.413.193.19
373.373.913.91
379.513.163.16
418.323.993.99
435.334.644.64
338.393.983.98
343.413.053.05
521.674.764.76
319.463.313.31
355.444.484.48
412.313.653.65
257.333.093.09
217.252.662.66
347.443.063.06
366.424.474.47
469.993.863.86
484.604.284.28
473.496.226.22
383.454.244.24
275.313.963.96
318.834.134.13
314.804.724.72
444.135.325.32
384.194.504.50
419.491.741.74
389.844.514.51
427.304.744.74
306.774.414.41
224.312.772.77
395.484.264.26
463.725.605.60
353.403.663.66
428.493.683.68
366.834.664.66
372.384.784.78
379.813.713.71
388.473.353.35
368.555.265.26
366.834.664.66
380.443.933.93
438.534.404.40
497.656.456.45
327.394.274.27
293.313.033.03
380.472.622.62
352.463.983.98
507.644.414.41
299.292.902.90
384.193.403.40
318.454.244.24
355.321.451.45
393.361.911.91
474.543.163.16
374.193.763.76
419.554.954.95
363.804.724.72
342.442.042.04
369.274.384.38
315.384.064.06
319.322.972.97
305.302.662.66
372.452.942.94
329.364.074.07
498.562.932.93
360.482.852.85
345.354.214.21
489.584.584.58
375.843.003.00
352.844.114.11
409.602.782.78
392.514.734.73
333.483.703.70
394.403.463.46
397.505.035.03
368.414.374.37
431.511.971.97
387.853.023.02
443.334.724.72
378.484.484.48
382.424.104.10
326.363.673.67
354.354.544.54