Basic Information
ID: ALA1614417
Type: Functional
Description: PUBCHEM_BIOASSAY: TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists. (Class of assay: confirmatory) [Related pubchem assays: 2379 (Confirmation (NR2E3 agonists in quadruplicate)), 2759 (Dose response counterscreen (PPARg and NCOR2 interaction agonists in triplicate)), 2758 (Dose response (NR2E3 agonists in quadruplicate)), 2325 (Summary (NR2E3 agonists)), 2300 (Primary screen (NR2E3 agonists in singlicate))]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614417
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.41 | 2.57 | 2.57 |
| 349.39 | 1.73 | 1.73 |
| 444.54 | 5.86 | 5.86 |
| 450.52 | 4.60 | 4.60 |
| 490.49 | 2.59 | 2.59 |
| 483.59 | 6.16 | 6.16 |
| 422.54 | 4.74 | 4.74 |
| 360.46 | 2.70 | 2.70 |
| 363.44 | 3.54 | 3.54 |
| 401.88 | 3.88 | 3.88 |
| 301.43 | 2.41 | 2.41 |
| 347.30 | 4.40 | 4.40 |
| 363.19 | 4.33 | 4.33 |
| 333.39 | 2.79 | 2.79 |
| 376.80 | 4.76 | 4.76 |
| 330.37 | 2.88 | 2.88 |
| 390.51 | 3.92 | 3.92 |
| 372.47 | 4.12 | 4.12 |
| 310.74 | 3.44 | 3.44 |
| 409.52 | 4.56 | 4.56 |
| 462.51 | 5.81 | 5.81 |
| 404.49 | 4.91 | 4.91 |
| 392.48 | 2.40 | 2.40 |
| 458.56 | 3.39 | 3.39 |
| 340.38 | 5.05 | 5.05 |
| 459.33 | 4.30 | 4.30 |
| 407.45 | 3.81 | 3.81 |
| 380.76 | 3.87 | 3.87 |
| 452.92 | 3.53 | 3.53 |
| 393.30 | 4.84 | 4.84 |
| 377.24 | 1.97 | 1.97 |
| 419.34 | 4.88 | 4.88 |
| 265.41 | 3.19 | 3.19 |
| 373.37 | 3.91 | 3.91 |
| 379.51 | 3.16 | 3.16 |
| 418.32 | 3.99 | 3.99 |
| 435.33 | 4.64 | 4.64 |
| 338.39 | 3.98 | 3.98 |
| 343.41 | 3.05 | 3.05 |
| 521.67 | 4.76 | 4.76 |
| 319.46 | 3.31 | 3.31 |
| 355.44 | 4.48 | 4.48 |
| 412.31 | 3.65 | 3.65 |
| 257.33 | 3.09 | 3.09 |
| 217.25 | 2.66 | 2.66 |
| 347.44 | 3.06 | 3.06 |
| 366.42 | 4.47 | 4.47 |
| 469.99 | 3.86 | 3.86 |
| 484.60 | 4.28 | 4.28 |
| 473.49 | 6.22 | 6.22 |
| 383.45 | 4.24 | 4.24 |
| 275.31 | 3.96 | 3.96 |
| 318.83 | 4.13 | 4.13 |
| 314.80 | 4.72 | 4.72 |
| 444.13 | 5.32 | 5.32 |
| 384.19 | 4.50 | 4.50 |
| 419.49 | 1.74 | 1.74 |
| 389.84 | 4.51 | 4.51 |
| 427.30 | 4.74 | 4.74 |
| 306.77 | 4.41 | 4.41 |
| 224.31 | 2.77 | 2.77 |
| 395.48 | 4.26 | 4.26 |
| 463.72 | 5.60 | 5.60 |
| 353.40 | 3.66 | 3.66 |
| 428.49 | 3.68 | 3.68 |
| 366.83 | 4.66 | 4.66 |
| 372.38 | 4.78 | 4.78 |
| 379.81 | 3.71 | 3.71 |
| 388.47 | 3.35 | 3.35 |
| 368.55 | 5.26 | 5.26 |
| 366.83 | 4.66 | 4.66 |
| 380.44 | 3.93 | 3.93 |
| 438.53 | 4.40 | 4.40 |
| 497.65 | 6.45 | 6.45 |
| 327.39 | 4.27 | 4.27 |
| 293.31 | 3.03 | 3.03 |
| 380.47 | 2.62 | 2.62 |
| 352.46 | 3.98 | 3.98 |
| 507.64 | 4.41 | 4.41 |
| 299.29 | 2.90 | 2.90 |
| 384.19 | 3.40 | 3.40 |
| 318.45 | 4.24 | 4.24 |
| 355.32 | 1.45 | 1.45 |
| 393.36 | 1.91 | 1.91 |
| 474.54 | 3.16 | 3.16 |
| 374.19 | 3.76 | 3.76 |
| 419.55 | 4.95 | 4.95 |
| 363.80 | 4.72 | 4.72 |
| 342.44 | 2.04 | 2.04 |
| 369.27 | 4.38 | 4.38 |
| 315.38 | 4.06 | 4.06 |
| 319.32 | 2.97 | 2.97 |
| 305.30 | 2.66 | 2.66 |
| 372.45 | 2.94 | 2.94 |
| 329.36 | 4.07 | 4.07 |
| 498.56 | 2.93 | 2.93 |
| 360.48 | 2.85 | 2.85 |
| 345.35 | 4.21 | 4.21 |
| 489.58 | 4.58 | 4.58 |
| 375.84 | 3.00 | 3.00 |
| 352.84 | 4.11 | 4.11 |
| 409.60 | 2.78 | 2.78 |
| 392.51 | 4.73 | 4.73 |
| 333.48 | 3.70 | 3.70 |
| 394.40 | 3.46 | 3.46 |
| 397.50 | 5.03 | 5.03 |
| 368.41 | 4.37 | 4.37 |
| 431.51 | 1.97 | 1.97 |
| 387.85 | 3.02 | 3.02 |
| 443.33 | 4.72 | 4.72 |
| 378.48 | 4.48 | 4.48 |
| 382.42 | 4.10 | 4.10 |
| 326.36 | 3.67 | 3.67 |
| 354.35 | 4.54 | 4.54 |