Basic Information
ID: ALA1614433
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV. (Class of assay: confirmatory) [Related pubchem assays: 1705, 1707 ]
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA1614433
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.29 | 1.77 | 1.77 |
| 252.27 | 1.77 | 1.77 |
| 290.32 | 1.26 | 1.26 |
| 121.14 | 0.79 | 0.79 |
| 270.24 | 2.58 | 2.58 |
| 329.36 | 4.06 | 4.06 |
| 211.22 | 0.44 | 0.44 |
| 335.45 | 5.43 | 5.43 |
| 1202.63 | ||
| 376.50 | 4.72 | 4.72 |
| 396.45 | 4.55 | 4.55 |
| 440.42 | 0.24 | 0.24 |
| 248.33 | 1.91 | 1.91 |
| 414.41 | 2.41 | 2.41 |
| 214.05 | 1.16 | 1.16 |
| 240.27 | 1.49 | 1.49 |
| 348.49 | 6.29 | 6.29 |
| 422.35 | 2.45 | 2.45 |
| 213.23 | 0.33 | 0.33 |
| 110.11 | 1.10 | 1.10 |
| 82.11 | 0.42 | 0.42 |
| 344.85 | 5.38 | 5.38 |
| 399.44 | 2.87 | 2.87 |
| 325.54 | 5.13 | 5.13 |
| 403.98 | 3.94 | 3.94 |
| 212.17 | 2.89 | 2.89 |
| 129.16 | 0.07 | 0.07 |
| 253.27 | 0.83 | 0.83 |
| 331.35 | 4.65 | 4.65 |
| 314.34 | 3.03 | 3.03 |
| 471.69 | 6.45 | 6.45 |
| 371.40 | 0.36 | 0.36 |
| 403.53 | 4.06 | 4.06 |
| 246.31 | 2.79 | 2.79 |
| 246.31 | 4.49 | 4.49 |
| 502.77 | 7.28 | 7.28 |
| 278.31 | 0.19 | 0.19 |
| 360.84 | 4.68 | 4.68 |
| 330.34 | 2.19 | 2.19 |
| 358.55 | 6.90 | 6.90 |
| 322.19 | 0.32 | 0.32 |
| 472.38 | 5.00 | 5.00 |
| 215.03 | 3.10 | 3.10 |
| 179.22 | 2.12 | 2.12 |
| 189.13 | -2.46 | -2.46 |
| 110.11 | 1.10 | 1.10 |
| 180.16 | 1.20 | 1.20 |
| 183.10 | -1.03 | -1.03 |
| 352.74 | 5.22 | 5.22 |
| 271.28 | 1.50 | 1.50 |
| 302.24 | 1.99 | 1.99 |
| 395.47 | 4.23 | 4.23 |
| 608.69 | 4.17 | 4.17 |
| 185.07 | -1.49 | -1.49 |
| 393.35 | -2.68 | -2.68 |
| 266.73 | 2.51 | 2.51 |
| 139.09 | -0.49 | -0.49 |
| 165.21 | -0.37 | -0.37 |
| 312.80 | 2.57 | 2.57 |
| 563.65 | 6.00 | 6.00 |
| 393.51 | 1.60 | 1.60 |
| 369.47 | 3.46 | 3.46 |
| 276.21 | 3.21 | 3.21 |
| 261.12 | 0.57 | 0.57 |
| 180.21 | 2.78 | 2.78 |
| 311.41 | 1.77 | 1.77 |
| 582.79 | 6.80 | 6.80 |
| 1429.19 | ||
| 292.14 | 1.76 | 1.76 |
| 475.58 | 5.31 | 5.31 |
| 368.52 | 5.11 | 5.11 |
| 370.46 | 5.59 | 5.59 |
| 428.44 | 2.54 | 2.54 |
| 318.20 | 1.58 | 1.58 |
| 302.41 | 3.62 | 3.62 |
| 365.84 | 2.71 | 2.71 |
| 336.44 | 2.75 | 2.75 |
| 327.18 | 4.09 | 4.09 |
| 140.03 | -0.75 | -0.75 |
| 494.08 | 8.01 | 8.01 |
| 294.31 | 2.32 | 2.32 |
| 209.20 | 0.64 | 0.64 |
| 515.87 | 4.81 | 4.81 |
| 340.85 | 4.30 | 4.30 |
| 379.46 | 2.25 | 2.25 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 455.56 | 3.97 | 3.97 |
| 398.30 | 1.06 | 1.06 |
| 448.44 | 1.65 | 1.65 |
| 307.40 | 2.77 | 2.77 |
| 384.31 | 2.08 | 2.08 |
| 224.22 | -0.71 | -0.71 |
| 299.50 | 3.92 | 3.92 |
| 225.18 | 0.14 | 0.14 |
| 304.31 | 3.37 | 3.37 |
| 477.46 | -0.62 | -0.62 |
| 326.44 | 3.52 | 3.52 |
| 371.40 | 4.34 | 4.34 |
| 317.22 | 2.60 | 2.60 |
| 246.31 | 1.38 | 1.38 |
| 665.68 | 5.03 | 5.03 |
| 215.17 | 1.73 | 1.73 |
| 293.41 | 3.77 | 3.77 |
| 202.17 | 1.23 | 1.23 |
| 186.17 | 1.53 | 1.53 |
| 318.14 | 4.36 | 4.36 |
| 330.47 | 3.84 | 3.84 |
| 304.39 | 3.15 | 3.15 |
| 129.16 | 0.36 | 0.36 |
| 264.33 | 3.25 | 3.25 |
| 213.24 | 3.51 | 3.51 |
| 401.51 | 1.03 | 1.03 |
| 127.14 | -0.19 | -0.19 |
| 347.41 | 4.24 | 4.24 |
| 373.88 | 2.90 | 2.90 |
| 286.36 | 3.59 | 3.59 |
| 334.42 | 2.30 | 2.30 |
| 375.85 | 3.86 | 3.86 |
| 313.79 | 3.43 | 3.43 |
| 510.06 | 6.08 | 6.08 |
| 497.50 | 1.02 | 1.02 |
| 371.22 | 4.05 | 4.05 |
| 284.31 | 2.90 | 2.90 |
| 213.19 | -0.24 | -0.24 |
| 228.25 | 0.63 | 0.63 |
| 331.76 | 3.21 | 3.21 |
| 180.17 | -1.04 | -1.04 |
| 325.06 | -1.45 | -1.45 |
| 527.58 | 6.17 | 6.17 |
| 304.35 | 3.84 | 3.84 |
| 152.15 | 0.00 | 0.00 |
| 386.45 | 5.28 | 5.28 |
| 165.71 | 1.88 | 1.88 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 1162.89 | ||
| 195.22 | 0.78 | 0.78 |
| 206.33 | 2.79 | 2.79 |
| 304.25 | 1.19 | 1.19 |
| 187.16 | 0.85 | 0.85 |
| 377.49 | 3.61 | 3.61 |
| 180.23 | -0.54 | -0.54 |
| 491.07 | 5.09 | 5.09 |
| 168.15 | 0.72 | 0.72 |
| 402.44 | 3.86 | 3.86 |
| 243.29 | 2.36 | 2.36 |
| 361.53 | 5.33 | 5.33 |
| 356.18 | 5.18 | 5.18 |
| 345.47 | 3.94 | 3.94 |
| 176.18 | -1.80 | -1.80 |
| 206.28 | 3.07 | 3.07 |
| 332.48 | 3.77 | 3.77 |
| 86.09 | 0.16 | 0.16 |
| 357.41 | -1.25 | -1.25 |
| 270.37 | 3.82 | 3.82 |
| 197.19 | 0.05 | 0.05 |
| 461.56 | 5.86 | 5.86 |
| 418.45 | 2.97 | 2.97 |
| 255.23 | -1.97 | -1.97 |
| 130.08 | -0.80 | -0.80 |
| 362.23 | 4.06 | 4.06 |
| 476.79 | 4.68 | 4.68 |
| 360.01 | 3.51 | 3.51 |
| 327.12 | 3.86 | 3.86 |
| 161.14 | 0.76 | 0.76 |
| 178.14 | 1.20 | 1.20 |
| 191.19 | 1.50 | 1.50 |
| 384.26 | 3.96 | 3.96 |
| 380.35 | -2.04 | -2.04 |
| 376.91 | 3.62 | 3.62 |
| 163.14 | 1.47 | 1.47 |
| 417.63 | 6.79 | 6.79 |
| 210.30 | 2.98 | 2.98 |
| 346.47 | 2.81 | 2.81 |
| 360.45 | 1.99 | 1.99 |
| 388.43 | -0.29 | -0.29 |
| 266.47 | 3.04 | 3.04 |
| 260.25 | 0.37 | 0.37 |
| 241.25 | 1.91 | 1.91 |
| 308.34 | 2.88 | 2.88 |
| 308.34 | 2.88 | 2.88 |
| 428.49 | 0.83 | 0.83 |
| 377.34 | 3.29 | 3.29 |
| 102.09 | -1.62 | -1.62 |
| 419.87 | 1.78 | 1.78 |
| 367.79 | 3.43 | 3.43 |
| 248.32 | 2.76 | 2.76 |
| 291.82 | 3.35 | 3.35 |
| 311.78 | 0.72 | 0.72 |
| 311.34 | 3.21 | 3.21 |
| 352.87 | 5.43 | 5.43 |
| 443.42 | 4.66 | 4.66 |
| 397.92 | 3.23 | 3.23 |
| 240.76 | 2.15 | 2.15 |
| 472.89 | 5.97 | 5.97 |
| 523.50 | 5.32 | 5.32 |
| 477.43 | 5.39 | 5.39 |
| 410.74 | 3.93 | 3.93 |
| 386.88 | 3.17 | 3.17 |
| 324.25 | 3.67 | 3.67 |
| 513.51 | 5.09 | 5.09 |
| 348.27 | 3.13 | 3.13 |
| 212.68 | 1.37 | 1.37 |
| 443.97 | 4.95 | 4.95 |
| 247.72 | 1.13 | 1.13 |
| 355.33 | 4.89 | 4.89 |
| 308.64 | 3.33 | 3.33 |
| 378.34 | 5.07 | 5.07 |
| 419.15 | 4.02 | 4.02 |
| 387.81 | 1.80 | 1.80 |
| 376.58 | 5.66 | 5.66 |
| 172.32 | 2.02 | 2.02 |
| 340.39 | 3.94 | 3.94 |
| 405.80 | 4.40 | 4.40 |
| 452.56 | 3.91 | 3.91 |
| 402.44 | 1.90 | 1.90 |
| 459.29 | -0.26 | -0.26 |
| 681.78 | 6.94 | 6.94 |
| 515.99 | 3.68 | 3.68 |
| 244.72 | 1.16 | 1.16 |
| 299.85 | 4.30 | 4.30 |
| 281.57 | 1.76 | 1.76 |
| 337.85 | 2.96 | 2.96 |
| 750.71 | 3.19 | 3.19 |
| 679.80 | 2.08 | 2.08 |
| 284.36 | 2.21 | 2.21 |
| 1485.73 | ||
| 311.86 | 4.55 | 4.55 |
| 340.29 | 4.19 | 4.19 |
| 272.78 | 1.77 | 1.77 |
| 480.10 | 3.47 | 3.47 |
| 407.05 | 5.89 | 5.89 |
| 410.51 | 4.12 | 4.12 |
| 313.87 | 4.17 | 4.17 |
| 891.54 | 5.45 | 5.45 |
| 445.45 | 0.48 | 0.48 |
| 493.53 | -0.73 | -0.73 |
| 445.90 | 3.77 | 3.77 |
| 226.23 | -0.05 | -0.05 |
| 593.64 | 4.21 | 4.21 |
| 335.88 | 3.43 | 3.43 |
| 687.71 | 10.29 | 10.29 |
| 271.27 | 1.16 | 1.16 |
| 522.62 | 4.60 | 4.60 |
| 246.22 | 1.93 | 1.93 |
| 1505.11 | ||
| 276.12 | 0.82 | 0.82 |
| 247.29 | 2.08 | 2.08 |
| 260.13 | 0.42 | 0.42 |
| 313.07 | 3.51 | 3.51 |
| 300.83 | 2.62 | 2.62 |
| 176.60 | 0.03 | 0.03 |
| 318.26 | 2.76 | 2.76 |
| 357.62 | 2.20 | 2.20 |
| 256.74 | 3.48 | 3.48 |
| 392.45 | 2.78 | 2.78 |
| 293.71 | -1.76 | -1.76 |
| 276.29 | 2.01 | 2.01 |
| 321.23 | 1.73 | 1.73 |
| 369.25 | 3.12 | 3.12 |
| 249.63 | 1.56 | 1.56 |
| 183.59 | ||
| 328.29 | 3.37 | 3.37 |
| 294.15 | -0.60 | -0.60 |
| 592.12 | 4.26 | 4.26 |
| 294.18 | 1.82 | 1.82 |
| 299.77 | 0.22 | 0.22 |
| 197.73 | 0.97 | 0.97 |
| 726.92 | 5.21 | 5.21 |
| 328.23 | 2.39 | 2.39 |
| 162.58 | 0.04 | 0.04 |
| 199.64 | 1.29 | 1.29 |
| 111.53 | -1.47 | -1.47 |
| 179.65 | 0.73 | 0.73 |
| 292.21 | 2.55 | 2.55 |
| 277.23 | 0.60 | 0.60 |
| 280.84 | 3.15 | 3.15 |
| 279.68 | -2.56 | -2.56 |
| 265.34 | 0.07 | 0.07 |
| 184.08 | ||
| 203.67 | 0.86 | 0.86 |
| 168.15 | 1.22 | 1.22 |
| 386.67 | 2.73 | 2.73 |
| 386.03 | ||
| 377.91 | 3.24 | 3.24 |
| 429.93 | 4.51 | 4.51 |
| 455.19 | 4.04 | 4.04 |
| 460.98 | 4.34 | 4.34 |
| 376.95 | 4.83 | 4.83 |
| 430.95 | 4.04 | 4.04 |
| 423.90 | 1.06 | 1.06 |
| 330.41 | 2.22 | 2.22 |
| 325.80 | 2.44 | 2.44 |
| 381.29 | 0.94 | 0.94 |
| 523.63 | 5.53 | 5.53 |
| 450.42 | 3.26 | 3.26 |
| 349.40 | 3.65 | 3.65 |
| 525.60 | 3.40 | 3.40 |
| 292.46 | 4.55 | 4.55 |
| 474.40 | 2.89 | 2.89 |
| 408.52 | 2.80 | 2.80 |
| 423.95 | 0.72 | 0.72 |
| 399.31 | 5.56 | 5.56 |
| 452.67 | 4.40 | 4.40 |
| 439.83 | 5.73 | 5.73 |
| 290.45 | 4.75 | 4.75 |
| 394.34 | 4.06 | 4.06 |
| 397.99 | 4.84 | 4.84 |
| 345.91 | 4.20 | 4.20 |
| 300.31 | 3.34 | 3.34 |
| 436.08 | 5.56 | 5.56 |
| 364.90 | 1.17 | 1.17 |
| 401.84 | 1.07 | 1.07 |
| 398.42 | 2.91 | 2.91 |
| 285.77 | 1.94 | 1.94 |
| 346.38 | 2.68 | 2.68 |
| 466.48 | 0.42 | 0.42 |
| 303.79 | 2.65 | 2.65 |
| 395.93 | 3.44 | 3.44 |
| 298.35 | 1.02 | 1.02 |
| 354.41 | 2.85 | 2.85 |
| 296.80 | 1.80 | 1.80 |
| 334.37 | 4.94 | 4.94 |
| 312.25 | 2.91 | 2.91 |
| 319.32 | 0.77 | 0.77 |
| 376.29 | 3.27 | 3.27 |
| 423.34 | 4.33 | 4.33 |
| 538.65 | 3.83 | 3.83 |
| 390.15 | 3.84 | 3.84 |
| 437.19 | 3.21 | 3.21 |
| 373.92 | 4.24 | 4.24 |
| 374.67 | 4.10 | 4.10 |
| 364.24 | 2.56 | 2.56 |
| 361.29 | 2.48 | 2.48 |
| 363.41 | 2.77 | 2.77 |
| 403.01 | 4.83 | 4.83 |
| 461.21 | 2.63 | 2.63 |
| 313.83 | 2.30 | 2.30 |
| 437.96 | 4.22 | 4.22 |
| 429.60 | 5.41 | 5.41 |
| 606.10 | 4.58 | 4.58 |
| 445.43 | 1.64 | 1.64 |
| 766.59 | 7.73 | 7.73 |
| 626.39 | 2.16 | 2.16 |
| 481.48 | 3.98 | 3.98 |
| 538.59 | 2.64 | 2.64 |
| 356.26 | 1.81 | 1.81 |
| 336.56 | 7.30 | 7.30 |
| 242.24 | 0.09 | 0.09 |
| 487.52 | 5.04 | 5.04 |
| 407.46 | 3.08 | 3.08 |
| 304.78 | 2.72 | 2.72 |
| 327.43 | 5.74 | 5.74 |
| 269.69 | -1.43 | -1.43 |
| 314.17 | -1.70 | -1.70 |
| 316.57 | 3.41 | 3.41 |
| 840.12 | 3.85 | 3.85 |
| 287.75 | 4.00 | 4.00 |
| 282.47 | 6.11 | 6.11 |
| 213.67 | 4.04 | 4.04 |
| 489.59 | 5.17 | 5.17 |
| 648.26 | 1.27 | 1.27 |
| 268.23 | 0.97 | 0.97 |
| 223.63 | 0.23 | 0.23 |
| 399.41 | -0.61 | -0.61 |
| 539.24 | -1.02 | -1.02 |
| 384.27 | 0.92 | 0.92 |
| 242.25 | 2.15 | 2.15 |
| 220.25 | 1.29 | 1.29 |
| 598.56 | -1.20 | -1.20 |
| 335.30 | 1.99 | 1.99 |
| 517.41 | -0.14 | -0.14 |
| 198.10 | 0.30 | 0.30 |
| 286.72 | 1.87 | 1.87 |
| 455.51 | 1.92 | 1.92 |
| 923.05 | 3.52 | 3.52 |
| 588.56 | 1.69 | 1.69 |
| 510.45 | 4.31 | 4.31 |
| 353.89 | 2.76 | 2.76 |
| 591.24 | 1.52 | 1.52 |
| 501.32 | 0.26 | 0.26 |
| 232.60 | 0.67 | 0.67 |
| 426.30 | 3.09 | 3.09 |
| 425.11 | 1.85 | 1.85 |
| 464.13 | 6.34 | 6.34 |
| 340.47 | 2.93 | 2.93 |
| 301.52 | 4.15 | 4.15 |
| 300.05 | ||
| 694.37 | 2.49 | 2.49 |
| 786.36 | ||
| 507.45 | 4.60 | 4.60 |
| 288.86 | 0.43 | 0.43 |
| 337.43 | 3.11 | 3.11 |
| 436.43 | 3.31 | 3.31 |
| 564.57 | 5.96 | 5.96 |
| 613.69 | 5.16 | 5.16 |
| 568.56 | 5.27 | 5.27 |
| 274.25 | -2.01 | -2.01 |
| 612.75 | 3.80 | 3.80 |
| 432.50 | 0.50 | 0.50 |
| 348.19 | -0.36 | -0.36 |
| 596.85 | 8.91 | 8.91 |
| 390.48 | 3.71 | 3.71 |
| 280.67 | 0.19 | 0.19 |
| 554.54 | -1.89 | -1.89 |
| 402.92 | 4.15 | 4.15 |
| 465.42 | 3.41 | 3.41 |
| 352.33 | 5.19 | 5.19 |
| 234.21 | 0.62 | 0.62 |
| 781.46 | -3.00 | -3.00 |
| 322.86 | 3.70 | 3.70 |
| 677.62 | 3.54 | 3.54 |
| 629.56 | -0.98 | -0.98 |
| 887.48 | -2.45 | -2.45 |
| 392.29 | 3.34 | 3.34 |
| 220.23 | 4.43 | 4.43 |
| 319.27 | 0.09 | 0.09 |
| 361.35 | 1.13 | 1.13 |
| 616.84 | 5.75 | 5.75 |
| 602.59 | ||
| 734.72 | 3.82 | 3.82 |