ID: ALA1614434
Type: Functional
Description: PUBCHEM_BIOASSAY: TR-FRET dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPAR gamma): non-selective agonists. (Class of assay: confirmatory) [Related pubchem assays: 1297, 1032 ]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1614434
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
223.23 | 2.31 | 2.31 |
289.74 | 4.31 | 4.31 |
399.45 | 3.39 | 3.39 |
319.86 | 2.50 | 2.50 |
285.39 | 4.93 | 4.93 |
234.28 | 2.16 | 2.16 |
253.26 | 2.05 | 2.05 |
178.22 | 2.40 | 2.40 |
342.38 | 3.83 | 3.83 |
386.48 | 5.51 | 5.51 |
244.66 | 2.53 | 2.53 |
450.52 | 4.60 | 4.60 |
481.51 | 2.36 | 2.36 |
381.46 | 3.54 | 3.54 |
444.00 | 3.92 | 3.92 |
404.33 | 4.11 | 4.11 |
361.40 | 2.98 | 2.98 |
469.59 | 6.08 | 6.08 |
449.35 | 4.94 | 4.94 |
356.42 | 3.09 | 3.09 |
339.42 | 3.15 | 3.15 |
406.49 | 5.02 | 5.02 |
447.49 | 3.13 | 3.13 |
367.45 | 3.85 | 3.85 |
309.35 | 3.21 | 3.21 |
384.46 | 2.58 | 2.58 |
492.26 | 4.77 | 4.77 |
331.35 | 2.82 | 2.82 |
398.46 | 5.13 | 5.13 |
317.40 | 3.32 | 3.32 |
345.47 | 1.89 | 1.89 |
293.37 | 2.71 | 2.71 |
292.43 | 3.46 | 3.46 |
257.11 | 2.79 | 2.79 |
332.43 | 1.97 | 1.97 |
384.53 | 4.47 | 4.47 |
427.53 | 2.44 | 2.44 |
323.78 | 3.06 | 3.06 |
386.79 | 3.60 | 3.60 |
224.31 | 2.75 | 2.75 |
325.39 | 2.66 | 2.66 |
482.63 | 3.58 | 3.58 |
413.30 | 4.45 | 4.45 |
441.58 | 4.63 | 4.63 |
403.50 | 2.37 | 2.37 |
246.65 | 3.31 | 3.31 |
216.22 | -0.55 | -0.55 |
358.45 | 3.14 | 3.14 |
367.52 | 3.90 | 3.90 |
349.43 | 4.27 | 4.27 |
365.48 | 3.01 | 3.01 |
366.42 | 4.14 | 4.14 |
432.32 | 2.52 | 2.52 |
456.45 | 4.06 | 4.06 |
373.52 | 2.71 | 2.71 |
396.47 | 3.16 | 3.16 |
337.40 | 4.25 | 4.25 |
465.58 | 3.19 | 3.19 |
233.29 | 2.80 | 2.80 |
311.79 | 2.85 | 2.85 |
326.40 | 4.41 | 4.41 |
339.42 | 2.34 | 2.34 |
412.47 | 5.05 | 5.05 |
403.49 | 6.25 | 6.25 |
359.50 | 2.28 | 2.28 |
244.28 | 0.23 | 0.23 |
346.45 | 2.41 | 2.41 |
509.98 | 1.95 | 1.95 |
332.39 | 4.54 | 4.54 |
414.90 | 3.76 | 3.76 |
380.47 | 2.81 | 2.81 |
302.33 | 3.74 | 3.74 |
204.22 | 2.37 | 2.37 |
211.68 | 2.41 | 2.41 |
367.26 | 4.67 | 4.67 |
475.52 | 3.86 | 3.86 |
369.83 | 4.76 | 4.76 |
327.61 | 4.38 | 4.38 |
315.35 | 3.12 | 3.12 |
353.45 | 3.46 | 3.46 |
439.32 | 3.35 | 3.35 |
377.47 | 3.66 | 3.66 |
452.92 | 3.53 | 3.53 |
395.51 | 4.97 | 4.97 |
393.42 | 4.46 | 4.46 |
483.35 | 3.19 | 3.19 |
423.49 | 4.52 | 4.52 |
436.99 | 6.51 | 6.51 |
313.38 | 3.93 | 3.93 |
302.40 | 2.25 | 2.25 |
269.26 | 1.49 | 1.49 |
295.13 | 3.73 | 3.73 |
340.36 | 4.05 | 4.05 |
372.88 | 4.41 | 4.41 |
242.69 | 2.69 | 2.69 |
466.40 | 6.23 | 6.23 |
342.42 | 3.02 | 3.02 |
310.35 | 4.81 | 4.81 |
288.40 | 3.67 | 3.67 |
425.55 | 3.59 | 3.59 |
285.33 | 3.36 | 3.36 |
294.42 | 4.51 | 4.51 |
203.31 | 3.39 | 3.39 |
460.44 | 4.53 | 4.53 |
452.61 | 5.07 | 5.07 |
359.86 | 4.73 | 4.73 |
280.40 | 3.39 | 3.39 |
325.39 | 2.66 | 2.66 |
278.34 | 3.75 | 3.75 |
344.48 | 3.37 | 3.37 |
521.67 | 4.76 | 4.76 |
265.27 | 3.80 | 3.80 |
297.38 | 3.70 | 3.70 |
294.41 | 2.55 | 2.55 |
262.26 | 1.83 | 1.83 |
264.38 | 2.68 | 2.68 |
431.97 | 5.46 | 5.46 |
395.80 | 3.81 | 3.81 |
328.39 | 2.54 | 2.54 |
390.44 | 5.34 | 5.34 |
355.44 | 4.48 | 4.48 |
386.48 | 5.51 | 5.51 |
490.47 | 4.54 | 4.54 |
395.47 | 2.71 | 2.71 |
330.45 | 3.13 | 3.13 |
453.20 | 5.28 | 5.28 |
368.46 | 2.96 | 2.96 |
433.51 | 4.14 | 4.14 |
244.15 | 4.20 | 4.20 |
307.28 | 3.18 | 3.18 |
370.48 | 5.41 | 5.41 |
332.31 | 4.52 | 4.52 |
396.47 | 3.52 | 3.52 |
353.45 | 3.46 | 3.46 |
417.38 | 4.58 | 4.58 |
259.29 | 1.95 | 1.95 |
244.34 | 3.65 | 3.65 |
372.35 | 4.46 | 4.46 |
468.60 | 3.10 | 3.10 |
489.58 | 5.31 | 5.31 |
464.57 | 4.86 | 4.86 |
252.36 | 3.57 | 3.57 |
378.50 | 4.85 | 4.85 |
530.68 | 4.71 | 4.71 |
423.45 | 3.79 | 3.79 |
411.48 | 2.21 | 2.21 |
289.36 | 3.89 | 3.89 |
241.70 | 2.66 | 2.66 |
354.50 | 4.31 | 4.31 |
354.46 | 5.25 | 5.25 |
444.00 | 3.92 | 3.92 |
383.45 | 4.24 | 4.24 |
419.30 | 4.18 | 4.18 |
361.87 | 4.85 | 4.85 |
314.39 | 4.02 | 4.02 |
371.44 | 4.30 | 4.30 |
376.51 | 5.18 | 5.18 |
339.42 | 2.97 | 2.97 |
424.46 | 4.65 | 4.65 |
350.40 | 4.21 | 4.21 |
317.46 | 3.59 | 3.59 |
331.42 | 4.67 | 4.67 |
411.53 | 3.20 | 3.20 |
468.60 | 3.10 | 3.10 |
404.45 | 4.18 | 4.18 |
413.54 | 3.45 | 3.45 |
366.49 | 3.77 | 3.77 |
364.40 | 2.62 | 2.62 |
272.33 | 1.01 | 1.01 |
425.51 | 2.69 | 2.69 |
305.79 | 2.92 | 2.92 |
359.45 | 4.86 | 4.86 |
403.38 | 4.72 | 4.72 |
203.29 | 1.92 | 1.92 |
349.40 | 1.33 | 1.33 |
406.47 | 2.60 | 2.60 |
473.71 | 5.18 | 5.18 |
332.47 | 3.28 | 3.28 |
400.84 | 3.74 | 3.74 |
352.46 | 3.29 | 3.29 |
342.47 | 4.84 | 4.84 |
465.75 | 6.38 | 6.38 |
402.52 | 2.92 | 2.92 |
374.31 | 4.52 | 4.52 |
310.35 | 4.81 | 4.81 |
267.36 | 3.53 | 3.53 |
369.08 | 5.49 | 5.49 |
354.88 | 4.83 | 4.83 |
352.84 | 2.14 | 2.14 |
330.16 | 2.85 | 2.85 |
226.30 | 2.25 | 2.25 |
258.30 | 0.62 | 0.62 |
420.02 | 4.71 | 4.71 |
490.44 | 5.88 | 5.88 |
426.99 | 6.00 | 6.00 |
294.43 | 3.87 | 3.87 |
226.30 | 2.39 | 2.39 |
291.37 | 2.68 | 2.68 |
332.15 | 4.03 | 4.03 |
428.49 | 3.68 | 3.68 |
417.32 | 4.71 | 4.71 |
246.12 | 3.07 | 3.07 |
329.98 | 2.76 | 2.76 |
318.85 | 5.16 | 5.16 |
317.37 | 2.21 | 2.21 |
230.29 | 2.84 | 2.84 |
385.38 | 3.36 | 3.36 |
417.53 | 2.85 | 2.85 |
407.45 | 3.33 | 3.33 |
454.59 | 4.27 | 4.27 |
366.51 | 4.71 | 4.71 |
366.49 | 3.74 | 3.74 |
388.49 | 2.48 | 2.48 |
346.41 | 3.08 | 3.08 |
329.15 | 2.89 | 2.89 |
209.30 | 2.08 | 2.08 |
355.08 | 4.32 | 4.32 |
406.01 | 2.72 | 2.72 |
478.23 | 4.38 | 4.38 |
398.48 | 3.77 | 3.77 |
425.53 | 3.60 | 3.60 |
430.42 | 4.21 | 4.21 |
440.57 | 3.79 | 3.79 |
368.48 | 5.55 | 5.55 |
281.77 | 3.08 | 3.08 |
409.94 | 2.12 | 2.12 |
368.46 | 2.96 | 2.96 |
405.45 | 5.79 | 5.79 |
341.44 | 3.92 | 3.92 |
471.61 | 5.77 | 5.77 |
359.88 | 3.81 | 3.81 |
430.33 | 4.38 | 4.38 |
345.45 | 4.20 | 4.20 |
583.69 | 5.07 | 5.07 |
388.49 | 2.43 | 2.43 |
304.42 | 2.55 | 2.55 |
258.30 | 3.06 | 3.06 |
323.42 | 3.63 | 3.63 |
464.64 | 3.05 | 3.05 |
268.36 | 2.77 | 2.77 |
320.22 | 4.07 | 4.07 |
509.39 | 4.10 | 4.10 |
347.42 | 3.54 | 3.54 |
374.46 | 2.00 | 2.00 |
257.32 | 3.12 | 3.12 |
328.48 | 3.20 | 3.20 |
408.52 | 4.86 | 4.86 |
334.21 | 4.27 | 4.27 |
345.47 | 3.39 | 3.39 |
387.51 | 5.46 | 5.46 |
489.02 | 3.36 | 3.36 |
227.74 | 3.75 | 3.75 |
343.20 | 3.76 | 3.76 |
376.51 | 5.53 | 5.53 |
404.47 | 3.96 | 3.96 |
482.63 | 3.58 | 3.58 |
308.37 | 3.36 | 3.36 |
314.21 | 2.79 | 2.79 |
408.53 | 2.86 | 2.86 |
409.24 | 3.47 | 3.47 |
418.45 | 4.71 | 4.71 |
288.37 | 2.85 | 2.85 |
414.90 | 3.76 | 3.76 |
458.03 | 4.31 | 4.31 |
258.30 | 0.62 | 0.62 |
283.36 | 3.23 | 3.23 |
364.47 | 4.12 | 4.12 |
393.51 | 2.98 | 2.98 |
396.31 | 5.36 | 5.36 |
315.15 | 1.84 | 1.84 |
215.28 | 2.87 | 2.87 |
507.03 | 6.71 | 6.71 |
317.44 | 3.85 | 3.85 |
192.24 | 2.33 | 2.33 |
307.38 | 3.80 | 3.80 |
212.20 | 2.65 | 2.65 |
285.33 | 2.98 | 2.98 |
351.23 | 3.34 | 3.34 |
336.84 | 2.91 | 2.91 |
482.59 | 3.63 | 3.63 |
336.38 | 2.78 | 2.78 |
302.40 | 5.47 | 5.47 |
340.47 | 4.25 | 4.25 |
394.50 | 2.37 | 2.37 |
398.42 | 3.00 | 3.00 |
342.43 | 4.79 | 4.79 |
291.77 | 2.61 | 2.61 |
410.45 | 4.14 | 4.14 |
330.37 | 2.99 | 2.99 |
372.45 | 5.20 | 5.20 |
244.32 | 3.88 | 3.88 |
514.62 | 3.86 | 3.86 |
414.85 | 5.21 | 5.21 |
495.00 | 4.67 | 4.67 |
396.29 | 4.64 | 4.64 |
250.32 | 2.52 | 2.52 |
301.37 | 3.55 | 3.55 |
413.59 | 3.59 | 3.59 |
560.23 | 4.30 | 4.30 |
318.38 | 4.16 | 4.16 |
312.44 | 4.14 | 4.14 |
400.93 | 5.08 | 5.08 |
305.40 | 4.92 | 4.92 |
337.84 | 4.96 | 4.96 |
450.45 | 3.79 | 3.79 |
319.32 | 3.36 | 3.36 |
437.57 | 3.47 | 3.47 |
367.50 | 3.96 | 3.96 |
258.30 | 0.48 | 0.48 |
468.35 | 3.37 | 3.37 |
332.43 | 1.93 | 1.93 |
191.28 | 3.51 | 3.51 |
415.38 | 5.39 | 5.39 |
339.38 | 3.38 | 3.38 |
466.33 | 2.93 | 2.93 |
378.48 | 3.81 | 3.81 |
208.24 | 2.03 | 2.03 |
408.91 | 2.65 | 2.65 |
393.94 | 2.88 | 2.88 |
359.77 | 4.13 | 4.13 |
420.42 | 3.78 | 3.78 |
397.41 | 3.23 | 3.23 |
289.38 | 3.14 | 3.14 |
378.45 | 4.38 | 4.38 |
353.38 | 4.25 | 4.25 |
392.47 | 4.72 | 4.72 |
428.51 | 3.78 | 3.78 |
272.37 | 2.94 | 2.94 |
316.32 | 4.24 | 4.24 |
375.84 | 3.00 | 3.00 |
286.40 | 3.43 | 3.43 |
469.34 | 4.34 | 4.34 |
386.48 | 3.11 | 3.11 |
382.44 | 3.48 | 3.48 |
375.45 | 4.45 | 4.45 |
319.38 | 3.56 | 3.56 |
495.56 | 4.79 | 4.79 |
354.50 | 4.31 | 4.31 |
451.55 | 2.70 | 2.70 |
425.55 | 3.55 | 3.55 |
398.53 | 3.62 | 3.62 |
345.90 | 4.82 | 4.82 |
340.83 | 2.05 | 2.05 |
368.41 | 3.00 | 3.00 |
386.90 | 4.77 | 4.77 |
475.76 | 5.84 | 5.84 |
415.52 | 5.30 | 5.30 |
281.38 | 3.84 | 3.84 |
367.41 | 3.92 | 3.92 |
422.54 | 5.58 | 5.58 |
328.44 | 5.37 | 5.37 |
460.44 | 4.53 | 4.53 |
365.41 | 3.47 | 3.47 |
353.45 | 2.82 | 2.82 |
392.43 | 5.07 | 5.07 |
318.43 | 2.98 | 2.98 |
353.38 | 4.25 | 4.25 |
317.44 | 4.55 | 4.55 |
296.21 | 4.79 | 4.79 |
366.87 | 2.58 | 2.58 |
345.47 | 1.79 | 1.79 |
327.82 | 4.75 | 4.75 |
462.50 | 3.75 | 3.75 |
300.34 | 2.63 | 2.63 |
452.95 | 3.49 | 3.49 |
434.45 | 4.17 | 4.17 |
397.44 | 2.26 | 2.26 |
377.47 | 5.06 | 5.06 |
471.56 | 3.37 | 3.37 |
291.36 | 2.46 | 2.46 |
301.39 | 4.17 | 4.17 |
331.44 | 1.40 | 1.40 |
306.44 | 4.04 | 4.04 |
222.27 | 2.42 | 2.42 |
351.39 | 3.16 | 3.16 |
403.39 | 5.13 | 5.13 |
311.41 | 3.71 | 3.71 |
257.31 | 3.68 | 3.68 |
336.84 | 2.91 | 2.91 |
279.36 | 4.67 | 4.67 |
394.50 | 3.12 | 3.12 |
430.33 | 4.38 | 4.38 |
407.31 | 3.91 | 3.91 |
326.36 | 1.03 | 1.03 |
307.19 | 3.94 | 3.94 |
461.98 | 3.59 | 3.59 |
296.33 | 1.66 | 1.66 |
366.85 | 5.19 | 5.19 |
307.14 | 4.12 | 4.12 |
405.55 | 3.10 | 3.10 |
380.88 | 5.50 | 5.50 |
355.37 | 3.99 | 3.99 |
401.29 | 5.84 | 5.84 |
340.38 | 1.42 | 1.42 |
426.30 | 4.53 | 4.53 |
482.38 | 4.99 | 4.99 |
343.37 | 1.12 | 1.12 |
439.34 | 5.45 | 5.45 |
371.44 | 4.80 | 4.80 |
294.34 | 2.92 | 2.92 |