Basic Information
ID: ALA1614443
Type: Functional
Description: PUBCHEM_BIOASSAY: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 2. (Class of assay: confirmatory) [Related pubchem assays: 2532 (Dose response (NOX1 inhibitors, HEK/293 cells)), 2664 (Dose response (NOX1 inhibitors, synthesized analogs)), 1792 (Primary Screen (NOX1 inhibitors)), 2556 (Dose response counterscreen (Xanthine Oxidase inhibitors)), 2538 (Dose response (NOX1 inhibitors)), 1796 (Summary AID (NOX1 inhibitors)), 2545 (Confirmation screen (NOX1 inhibitors, HEK/293 cells)), 2539 (Counterscreen (NOX2, NOX3, NOX4 inhibition)), 2541 (Confirmation screen (NOX1 inhibitors)), 1823 (Counterscreen (luminal))]
Format: BAO_0000219
Organism: Homo sapiens
Target: NADPH oxidase 1(ALA1287628)
Document: ALA1201862
PubChem Source: AID:2752
Activity Charts
Bioactivity
Activity Types for Assay ALA1614443
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.37 | 4.04 | 4.04 |
| 371.10 | 5.44 | 5.44 |
| 292.20 | 4.68 | 4.68 |
| 295.33 | 5.80 | 5.80 |
| 373.44 | 6.11 | 6.11 |
| 296.22 | 5.18 | 5.18 |
| 254.32 | 4.86 | 4.86 |
| 354.38 | 5.80 | 5.80 |
| 379.48 | 6.85 | 6.85 |
| 360.44 | 5.72 | 5.72 |
| 304.80 | 4.10 | 4.10 |
| 436.54 | 6.40 | 6.40 |