Basic Information
ID: ALA1614446
Type: ADME
Description: PUBCHEM_BIOASSAY: Confirmation Dose Response screen for compounds that protect hERG from block by proarrhythmic agents. (Class of assay: confirmatory) [Related pubchem assays: 1511 (Primary HTS assay for 305616 compounds.)]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614446
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.47 | 6.11 | 6.11 |
| 223.23 | 2.31 | 2.31 |
| 395.31 | 5.63 | 5.63 |
| 334.42 | 3.98 | 3.98 |
| 330.81 | 4.80 | 4.80 |
| 383.88 | 3.03 | 3.03 |
| 397.50 | 5.34 | 5.34 |
| 360.46 | 2.70 | 2.70 |
| 408.30 | 4.29 | 4.29 |
| 327.34 | 2.48 | 2.48 |
| 454.40 | 4.77 | 4.77 |
| 379.94 | 4.52 | 4.52 |
| 359.86 | 5.67 | 5.67 |
| 334.37 | 3.48 | 3.48 |
| 283.36 | 4.29 | 4.29 |
| 363.87 | 4.05 | 4.05 |
| 345.26 | 2.81 | 2.81 |
| 385.24 | 3.19 | 3.19 |
| 349.44 | 2.76 | 2.76 |
| 219.22 | 1.52 | 1.52 |
| 263.30 | 4.66 | 4.66 |
| 369.24 | 3.08 | 3.08 |
| 364.27 | 3.59 | 3.59 |
| 323.14 | 4.58 | 4.58 |
| 476.52 | 4.14 | 4.14 |
| 245.31 | 2.22 | 2.22 |
| 349.48 | 5.07 | 5.07 |
| 305.72 | 3.30 | 3.30 |
| 333.34 | 2.61 | 2.61 |
| 381.48 | 3.96 | 3.96 |
| 389.91 | 3.83 | 3.83 |
| 318.83 | 3.19 | 3.19 |
| 329.45 | 2.11 | 2.11 |
| 287.34 | 3.41 | 3.41 |
| 370.43 | 3.32 | 3.32 |
| 282.43 | 3.03 | 3.03 |
| 307.42 | 3.87 | 3.87 |
| 365.36 | 1.17 | 1.17 |
| 318.38 | 3.13 | 3.13 |
| 357.21 | 4.01 | 4.01 |
| 396.45 | 2.29 | 2.29 |
| 316.43 | 2.78 | 2.78 |
| 473.60 | 3.18 | 3.18 |
| 399.39 | 3.26 | 3.26 |
| 422.46 | 6.37 | 6.37 |
| 429.48 | 0.74 | 0.74 |
| 316.78 | 4.18 | 4.18 |
| 383.52 | 3.27 | 3.27 |
| 316.77 | 3.56 | 3.56 |
| 290.34 | 2.81 | 2.81 |
| 284.41 | 4.39 | 4.39 |
| 323.14 | 4.58 | 4.58 |
| 266.30 | 3.25 | 3.25 |
| 312.35 | 2.42 | 2.42 |
| 312.82 | 2.46 | 2.46 |
| 347.42 | 3.22 | 3.22 |
| 404.47 | 6.24 | 6.24 |
| 395.44 | 2.35 | 2.35 |
| 365.35 | 4.12 | 4.12 |
| 383.48 | 5.03 | 5.03 |
| 418.50 | 6.54 | 6.54 |
| 361.79 | 2.06 | 2.06 |
| 270.79 | 2.60 | 2.60 |
| 387.87 | 5.11 | 5.11 |
| 258.24 | 1.83 | 1.83 |
| 386.86 | 4.74 | 4.74 |
| 415.11 | 3.73 | 3.73 |
| 400.41 | 1.52 | 1.52 |
| 362.34 | 2.76 | 2.76 |
| 414.90 | 3.76 | 3.76 |
| 418.52 | 5.28 | 5.28 |
| 415.93 | 4.61 | 4.61 |
| 366.94 | 4.74 | 4.74 |
| 378.91 | 4.71 | 4.71 |
| 419.33 | 4.09 | 4.09 |
| 383.86 | 3.98 | 3.98 |
| 341.36 | 2.87 | 2.87 |
| 487.61 | 5.44 | 5.44 |
| 294.40 | 3.10 | 3.10 |
| 477.47 | 4.04 | 4.04 |
| 331.76 | 3.13 | 3.13 |
| 358.77 | 4.49 | 4.49 |
| 362.55 | 4.97 | 4.97 |
| 436.56 | 4.83 | 4.83 |
| 382.20 | 2.40 | 2.40 |
| 279.30 | 4.36 | 4.36 |
| 401.51 | 4.37 | 4.37 |
| 329.41 | 3.53 | 3.53 |
| 383.52 | 4.54 | 4.54 |
| 333.48 | 3.72 | 3.72 |
| 288.73 | 3.81 | 3.81 |
| 300.41 | 3.97 | 3.97 |
| 337.24 | 4.52 | 4.52 |
| 329.73 | 4.38 | 4.38 |
| 312.46 | 2.89 | 2.89 |
| 395.31 | 4.23 | 4.23 |
| 349.37 | 1.16 | 1.16 |
| 406.49 | 2.50 | 2.50 |
| 359.22 | 3.97 | 3.97 |
| 272.28 | 3.30 | 3.30 |
| 418.50 | 6.54 | 6.54 |
| 296.35 | 3.22 | 3.22 |
| 444.31 | 5.57 | 5.57 |
| 367.52 | 4.76 | 4.76 |
| 365.41 | 4.81 | 4.81 |
| 289.22 | 3.02 | 3.02 |
| 329.43 | 4.87 | 4.87 |
| 244.25 | 2.73 | 2.73 |
| 383.52 | 4.46 | 4.46 |
| 330.34 | 3.38 | 3.38 |
| 398.49 | 5.21 | 5.21 |
| 352.46 | 4.15 | 4.15 |
| 282.37 | 3.47 | 3.47 |
| 466.29 | 1.14 | 1.14 |