Basic Information
ID: ALA1614462
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response: Fluorescence polarization-based cell-based high throughput dose response assay for inhibitors of insulin-degrading enzyme (IDE). (Class of assay: confirmatory) [Related pubchem assays: 434962 (Primary screen (IDE inhibitors in singlicate)), 449730 (Counterscreen (Cytotoxicity in triplicate)), 435028 (Confirmation (IDE inhibitors in triplicate)), 434984 (Summary (IDE inhibitors))]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614462
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.34 | 4.48 | 4.48 |
| 287.32 | 3.57 | 3.57 |
| 268.27 | 3.17 | 3.17 |
| 305.39 | 4.08 | 4.08 |
| 345.83 | 2.90 | 2.90 |
| 329.40 | 2.47 | 2.47 |
| 209.25 | 2.42 | 2.42 |
| 342.37 | 3.20 | 3.20 |
| 414.47 | 3.50 | 3.50 |
| 463.55 | 4.07 | 4.07 |
| 333.35 | 2.82 | 2.82 |
| 344.37 | 3.60 | 3.60 |
| 426.48 | 3.55 | 3.55 |
| 377.44 | 3.25 | 3.25 |
| 456.55 | 3.62 | 3.62 |
| 381.39 | 2.09 | 2.09 |
| 315.44 | 3.21 | 3.21 |
| 326.35 | 2.72 | 2.72 |
| 354.39 | 4.11 | 4.11 |
| 271.30 | 2.75 | 2.75 |
| 433.51 | 4.06 | 4.06 |
| 375.50 | 1.99 | 1.99 |
| 441.96 | 5.03 | 5.03 |
| 313.39 | 2.85 | 2.85 |
| 319.79 | 3.17 | 3.17 |
| 438.57 | 4.30 | 4.30 |
| 461.57 | 1.91 | 1.91 |
| 275.35 | 2.56 | 2.56 |
| 294.31 | 3.32 | 3.32 |
| 405.45 | 3.69 | 3.69 |
| 355.40 | 2.35 | 2.35 |
| 443.55 | 3.72 | 3.72 |
| 356.40 | 3.49 | 3.49 |
| 471.59 | 4.80 | 4.80 |
| 486.98 | 3.67 | 3.67 |
| 426.56 | 4.02 | 4.02 |
| 335.36 | 3.46 | 3.46 |
| 252.34 | 1.64 | 1.64 |
| 279.29 | 0.95 | 0.95 |
| 326.35 | 2.63 | 2.63 |
| 302.40 | 3.70 | 3.70 |
| 455.56 | 3.58 | 3.58 |
| 391.47 | 3.25 | 3.25 |
| 388.51 | 3.54 | 3.54 |
| 427.46 | 3.30 | 3.30 |
| 329.83 | 3.34 | 3.34 |
| 406.31 | 3.78 | 3.78 |
| 482.53 | 3.88 | 3.88 |
| 245.28 | 1.66 | 1.66 |
| 328.76 | 2.97 | 2.97 |
| 307.38 | 1.38 | 1.38 |
| 395.42 | 3.30 | 3.30 |
| 341.80 | 3.44 | 3.44 |
| 352.87 | 2.09 | 2.09 |
| 457.57 | 3.97 | 3.97 |
| 407.39 | 3.03 | 3.03 |
| 240.35 | 1.63 | 1.63 |
| 290.33 | 3.10 | 3.10 |
| 290.33 | 3.10 | 3.10 |
| 331.44 | 1.99 | 1.99 |
| 404.56 | 2.46 | 2.46 |
| 418.45 | 2.76 | 2.76 |
| 421.91 | 5.41 | 5.41 |
| 424.52 | 3.19 | 3.19 |
| 458.91 | 4.94 | 4.94 |
| 464.51 | 3.24 | 3.24 |
| 388.50 | 4.92 | 4.92 |
| 375.48 | 2.47 | 2.47 |
| 386.41 | 2.44 | 2.44 |
| 364.47 | 0.91 | 0.91 |
| 253.35 | 3.81 | 3.81 |
| 409.40 | 2.67 | 2.67 |
| 403.46 | 1.43 | 1.43 |
| 368.91 | 3.81 | 3.81 |
| 528.65 | 3.60 | 3.60 |
| 378.43 | 3.15 | 3.15 |
| 493.99 | 3.85 | 3.85 |
| 401.50 | 5.06 | 5.06 |
| 429.86 | 3.96 | 3.96 |
| 429.50 | 2.97 | 2.97 |
| 461.35 | 3.64 | 3.64 |
| 360.44 | 4.79 | 4.79 |
| 305.38 | 3.24 | 3.24 |
| 395.37 | 2.27 | 2.27 |
| 371.41 | 4.04 | 4.04 |
| 453.55 | 3.60 | 3.60 |
| 406.41 | 2.67 | 2.67 |
| 386.04 | 4.71 | 4.71 |
| 280.42 | 2.86 | 2.86 |
| 392.46 | 3.46 | 3.46 |
| 287.38 | 3.56 | 3.56 |
| 177.16 | 1.35 | 1.35 |
| 569.65 | 5.33 | 5.33 |
| 462.38 | 4.93 | 4.93 |
| 419.30 | 4.64 | 4.64 |
| 480.37 | 5.07 | 5.07 |
| 447.56 | 3.15 | 3.15 |
| 441.96 | 5.03 | 5.03 |
| 443.55 | 4.01 | 4.01 |
| 424.55 | 5.10 | 5.10 |
| 401.41 | 2.86 | 2.86 |
| 288.31 | 2.53 | 2.53 |
| 361.47 | 4.88 | 4.88 |
| 364.52 | 3.20 | 3.20 |
| 331.85 | 3.58 | 3.58 |
| 362.45 | 4.92 | 4.92 |
| 395.44 | 2.82 | 2.82 |
| 331.37 | 1.32 | 1.32 |
| 460.88 | 3.10 | 3.10 |
| 350.83 | 3.79 | 3.79 |
| 380.43 | 2.00 | 2.00 |
| 489.62 | 3.41 | 3.41 |
| 351.32 | 4.00 | 4.00 |
| 363.64 | 5.35 | 5.35 |
| 320.80 | 3.78 | 3.78 |
| 271.32 | 4.50 | 4.50 |
| 339.18 | 4.11 | 4.11 |
| 384.33 | 1.98 | 1.98 |
| 317.34 | 5.05 | 5.05 |
| 346.39 | 3.33 | 3.33 |
| 297.38 | 4.76 | 4.76 |
| 282.35 | 1.59 | 1.59 |
| 281.38 | 5.06 | 5.06 |
| 265.36 | 2.50 | 2.50 |
| 423.27 | 3.86 | 3.86 |
| 361.41 | 3.83 | 3.83 |
| 414.47 | 2.93 | 2.93 |