Assay Report Card

Basic Information

ID: ALA1614466

Type: Functional

Description: PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)]

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
302.191.311.31
168.151.221.22
270.242.582.58
108.100.250.25
808.666.386.38
153.180.600.60
422.352.452.45
562.677.507.50
233.103.093.09
169.180.090.09
246.314.494.49
356.493.663.66
179.152.012.01
180.161.201.20
272.211.281.28
286.242.282.28
159.14-0.88-0.88
206.332.792.79
1429.19
300.221.281.28
174.161.331.33
418.430.590.59
240.211.871.87
494.088.018.01
308.312.762.76
297.272.302.30
338.311.881.88
318.241.691.69
220.181.021.02
288.252.222.22
274.373.673.67
458.382.232.23
497.501.021.02
314.252.822.82
371.224.054.05
213.19-0.24-0.24
360.321.761.76
1162.89
169.180.300.30
220.180.200.20
197.190.050.05
316.262.292.29
300.272.592.59
259.741.981.98
316.262.292.29
472.362.232.23
650.763.933.93
311.382.862.86
527.531.031.03
290.271.551.55
444.453.023.02
197.190.050.05
215.252.792.79
169.180.090.09
302.241.991.99
163.141.471.47
210.302.982.98
297.362.352.35
318.241.691.69
476.514.944.94
337.423.153.15
309.372.512.51
461.504.164.16
475.534.474.47
229.282.852.85
306.271.251.25
330.251.921.92
270.242.422.42
513.500.730.73
538.465.135.13
286.282.822.82
265.290.770.77
518.474.604.60
472.895.975.97
408.804.404.40
183.210.350.35
336.424.584.58
222.272.232.23
604.736.826.82
340.393.943.94
347.222.292.29
278.220.670.67
310.394.454.45
445.450.480.48
1505.11
277.230.600.60
168.151.221.22
437.193.213.21
461.212.632.63
449.533.773.77
231.211.871.87
442.952.662.66
448.38-0.20-0.20
420.404.194.19
422.824.394.39
453.524.594.59
358.403.413.41
334.383.603.60
271.272.472.47
360.324.164.16
487.515.415.41
294.691.801.80
436.494.284.28
282.342.242.24
310.402.142.14
306.363.443.44
299.291.281.28
464.963.683.68
266.301.811.81
319.382.912.91
323.310.970.97
255.072.892.89
441.513.063.06
385.453.363.36
325.322.122.12
310.283.603.60
618.696.086.08
604.706.366.36
263.262.612.61
364.433.423.42
862.75-1.10-1.10
334.354.784.78
453.46-0.54-0.54
992.826.076.07
294.291.561.56
358.381.371.37
277.713.263.26
292.383.353.35
429.464.284.28
337.363.393.39
429.464.284.28
260.251.471.47
252.660.830.83
329.311.881.88
378.372.992.99
382.465.155.15
279.322.122.12
381.433.783.78
762.633.473.47
282.252.752.75
203.200.470.47
295.382.662.66
561.66
422.34-0.72-0.72
346.34-0.06-0.06
206.18-0.87-0.87
575.665.895.89
224.240.410.41
358.404.324.32
300.343.373.37
834.813.863.86
381.844.184.18
490.545.255.25
267.243.333.33
287.312.072.07
402.441.771.77
360.374.434.43
327.373.423.42
286.292.202.20
373.431.621.62
389.442.632.63
194.221.211.21
428.243.373.37
468.686.626.62
442.574.134.13
282.302.282.28
276.303.893.89
318.133.673.67
419.443.133.13
407.813.933.93
396.414.474.47
300.313.433.43
444.453.023.02
376.252.662.66
348.794.894.89
428.942.682.68
359.383.993.99
316.444.014.01
539.714.124.12
393.424.384.38
524.622.292.29
318.403.013.01
317.342.632.63
300.313.123.12
348.453.033.03
407.994.754.75
376.373.883.88
251.171.241.24
295.433.513.51
432.501.221.22
339.151.911.91
316.573.413.41
224.333.873.87
403.464.574.57
290.382.692.69
484.50-0.23-0.23
250.712.652.65
329.312.262.26
245.283.753.75
840.123.853.85
341.392.622.62
366.401.001.00
492.39-1.19-1.19
563.664.154.15
352.421.721.72
904.896.076.07
303.311.911.91
432.324.524.52
269.212.082.08
345.363.063.06
356.332.272.27
217.222.202.20
275.261.751.75
468.293.573.57
466.543.903.90
305.383.273.27
378.393.653.65
280.373.123.12
281.311.721.72
610.52-2.42-2.42
262.332.322.32
229.282.532.53
457.275.045.04
433.902.752.75
422.444.554.55
295.342.422.42
381.433.593.59
523.603.333.33
334.303.973.97
412.852.382.38
347.432.882.88
247.673.153.15
277.351.891.89
392.444.304.30
376.463.023.02
515.623.013.01
452.473.183.18
415.453.923.92
184.15-0.59-0.59
389.485.235.23
338.391.411.41
956.680.020.02
290.271.931.93
315.375.115.11
371.422.192.19
422.853.013.01
914.734.454.45
392.18
218.251.741.74
264.312.262.26
422.824.074.07
357.422.782.78
346.393.363.36
493.543.783.78
408.214.394.39
208.170.250.25
260.321.841.84
461.504.164.16
402.443.223.22
409.352.622.62
249.231.221.22
291.394.414.41
326.311.951.95
308.363.823.82
381.244.574.57
370.793.573.57
277.351.861.86
788.66-4.89-4.89
225.25-1.40-1.40
598.56-1.20-1.20
310.223.993.99
315.423.373.37
432.523.363.36
392.482.932.93
517.41-0.14-0.14
166.180.960.96
405.393.413.41
383.454.244.24
331.173.413.41
594.52-1.39-1.39
287.362.972.97
398.283.303.30
304.372.262.26
427.572.292.29
515.566.016.01
527.626.026.02
372.502.102.10
366.373.423.42
634.46-0.30-0.30
371.365.405.40
461.273.313.31
376.753.523.52
283.282.552.55
278.313.393.39
444.453.023.02
389.413.353.35
328.352.842.84
416.483.603.60
460.543.033.03
381.413.503.50
388.504.674.67
477.46-0.62-0.62
318.241.691.69
371.381.151.15
570.463.013.01
329.36-0.70-0.70
360.333.403.40
310.384.234.23
442.420.560.56
426.434.434.43
307.373.313.31
462.512.472.47
527.575.885.88
408.424.654.65
257.252.632.63
375.483.393.39
476.514.944.94
286.332.022.02
280.412.782.78
868.714.184.18
260.251.471.47
411.443.613.61
486.614.584.58
400.494.074.07
426.564.024.02
290.373.573.57
324.413.883.88
258.232.422.42
375.381.021.02
446.373.043.04
372.431.441.44
262.262.922.92
473.601.201.20
405.393.413.41
282.713.493.49
420.472.622.62
369.381.391.39
351.794.194.19
415.471.751.75
388.473.353.35
492.513.243.24
250.281.411.41
448.38-0.20-0.20
412.313.613.61
314.321.811.81
304.193.383.38
319.363.173.17
496.573.993.99
350.423.063.06
432.514.014.01
199.301.961.96
332.361.951.95
329.142.452.45
388.384.054.05
477.504.434.43
448.495.415.41
338.340.400.40
388.331.901.90
267.283.813.81
278.332.802.80
345.382.802.80
694.372.492.49
484.643.653.65
410.43-0.05-0.05
450.834.804.80
361.313.043.04
329.403.953.95
229.323.053.05
256.303.033.03
301.394.184.18
341.153.183.18
940.681.691.69
423.435.605.60
347.173.603.60
479.004.974.97
438.463.303.30
441.474.954.95
355.351.911.91
314.251.501.50
265.291.811.81
487.473.503.50
237.323.023.02
496.952.882.88
466.833.553.55
374.703.543.54
564.502.212.21
333.324.284.28
524.604.174.17
426.522.732.73
294.314.324.32
445.483.053.05
451.455.005.00
337.89
366.401.001.00
416.434.354.35
373.441.821.82
347.391.901.90
402.414.054.05
458.594.594.59
433.423.053.05
359.412.872.87
245.282.232.23
396.313.243.24
312.353.533.53
479.482.082.08
378.451.381.38
349.394.194.19
349.354.804.80
408.803.763.76
542.593.913.91
564.50-1.75-1.75
331.713.613.61
365.413.033.03
314.182.662.66
307.142.932.93
404.474.204.20
339.381.101.10
343.383.163.16
444.453.023.02
406.474.744.74
438.512.712.71
416.483.603.60
297.312.762.76
295.773.303.30
262.291.091.09
188.610.550.55
447.242.922.92
393.361.981.98
333.402.632.63
351.363.553.55
226.281.351.35
334.413.373.37
293.332.032.03
359.433.053.05
243.312.512.51
377.972.552.55
285.73-0.78-0.78
326.311.951.95
262.221.101.10
465.512.922.92
177.161.601.60
457.302.492.49
421.453.253.25
267.333.113.11
319.311.771.77
331.432.672.67
846.97-1.87-1.87
405.823.943.94
465.601.671.67
373.373.273.27
482.615.385.38
354.320.950.95
329.313.223.22
682.15
352.393.463.46
247.322.552.55
383.432.902.90
489.584.584.58
257.292.912.91
410.454.864.86
402.455.565.56
392.444.434.43
385.452.352.35
491.744.124.12
339.404.014.01
332.334.384.38
316.324.244.24
364.493.103.10
344.292.992.99
196.200.980.98
333.341.921.92
416.414.654.65
314.342.612.61
316.743.833.83
262.262.872.87
323.402.902.90
288.22-0.04-0.04
368.422.912.91
286.262.512.51
427.443.593.59
305.722.412.41
312.352.232.23
314.272.082.08
280.302.262.26
406.474.744.74
346.843.633.63
371.553.773.77
448.522.842.84
477.904.114.11
374.493.123.12
452.473.903.90
448.864.714.71
313.272.822.82
502.593.303.30
469.505.145.14
402.441.691.69
279.393.953.95
148.170.730.73
351.865.625.62
372.452.732.73
243.262.602.60
326.303.153.15
331.445.285.28
252.291.741.74
312.282.092.09
427.571.411.41
432.380.090.09
278.170.720.72
275.382.712.71
336.393.593.59
416.415.025.02
325.393.933.93
288.323.183.18
275.301.651.65
264.283.473.47
250.251.471.47
491.433.303.30
410.954.984.98
462.484.634.63
334.444.764.76
457.614.374.37
234.282.072.07
447.443.273.27
380.454.714.71
300.271.081.08
300.363.103.10
368.330.800.80
397.463.213.21
299.311.861.86
404.252.732.73
286.292.552.55
464.431.801.80
355.351.381.38
415.314.814.81
375.412.362.36
325.351.971.97
303.342.072.07
427.371.731.73
277.24-0.04-0.04
388.403.423.42
238.240.470.47
397.463.213.21
290.753.893.89
230.221.981.98
471.432.782.78
530.615.495.49
348.363.333.33
258.240.410.41
298.251.431.43
337.361.241.24
325.280.610.61
378.264.444.44
333.300.470.47
279.321.391.39
387.403.273.27
448.483.323.32
360.432.092.09
374.222.722.72
378.410.790.79
365.392.972.97
308.292.932.93
436.853.693.69
205.180.620.62
264.272.202.20
340.413.073.07
416.554.334.33
412.423.243.24
379.380.070.07
365.392.782.78
739.967.317.31
770.73-6.34-6.34