Basic Information
ID: ALA1614482
Type: Binding
Description: PUBCHEM_BIOASSAY: MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1054, AID1055, AID425, AID553, AID566]
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1614482
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 152.15 | 0.80 | 0.80 |
| 152.15 | 0.80 | 0.80 |
| 267.24 | 2.19 | 2.19 |
| 294.15 | 2.99 | 2.99 |
| 259.26 | 1.92 | 1.92 |
| 243.31 | 2.97 | 2.97 |
| 258.28 | 1.32 | 1.32 |
| 152.15 | 0.80 | 0.80 |
| 215.25 | 2.23 | 2.23 |
| 296.41 | 4.01 | 4.01 |
| 503.43 | 4.00 | 4.00 |
| 222.27 | 2.23 | 2.23 |
| 248.37 | 4.00 | 4.00 |
| 278.29 | 1.13 | 1.13 |
| 291.35 | 2.52 | 2.52 |
| 234.28 | 2.70 | 2.70 |
| 290.32 | 0.68 | 0.68 |
| 278.52 | 7.27 | 7.27 |
| 233.24 | 2.36 | 2.36 |
| 283.25 | 3.24 | 3.24 |
| 332.40 | 2.13 | 2.13 |
| 234.25 | 2.46 | 2.46 |
| 243.31 | 2.84 | 2.84 |
| 287.32 | 2.40 | 2.40 |
| 295.43 | 3.51 | 3.51 |
| 409.44 | 1.42 | 1.42 |
| 341.15 | 2.83 | 2.83 |
| 284.14 | 3.53 | 3.53 |
| 404.25 | 4.75 | 4.75 |
| 369.83 | 5.34 | 5.34 |
| 468.29 | 3.57 | 3.57 |
| 315.37 | 3.04 | 3.04 |
| 245.28 | 2.24 | 2.24 |
| 304.26 | 1.83 | 1.83 |
| 203.20 | 1.52 | 1.52 |
| 229.28 | 2.53 | 2.53 |
| 230.27 | 2.47 | 2.47 |
| 420.72 | 9.46 | 9.46 |
| 208.17 | 0.25 | 0.25 |
| 208.24 | 2.30 | 2.30 |
| 273.33 | 2.72 | 2.72 |
| 259.30 | 2.41 | 2.41 |
| 294.33 | 0.87 | 0.87 |
| 245.28 | 2.24 | 2.24 |
| 333.34 | 0.08 | 0.08 |
| 386.80 | 0.61 | 0.61 |
| 283.28 | 2.55 | 2.55 |
| 450.57 | 4.71 | 4.71 |
| 310.69 | 2.49 | 2.49 |
| 294.29 | 0.51 | 0.51 |
| 273.33 | 2.72 | 2.72 |
| 243.31 | 2.84 | 2.84 |
| 308.34 | 1.58 | 1.58 |
| 338.75 | 0.02 | 0.02 |
| 392.67 | 3.27 | 3.27 |
| 259.29 | 3.11 | 3.11 |
| 335.39 | 4.68 | 4.68 |
| 375.41 | 4.29 | 4.29 |
| 355.42 | 3.06 | 3.06 |
| 493.17 | 5.18 | 5.18 |
| 355.18 | 3.14 | 3.14 |
| 318.59 | 4.19 | 4.19 |
| 274.32 | 1.26 | 1.26 |
| 318.33 | -0.32 | -0.32 |
| 388.40 | 3.42 | 3.42 |
| 276.25 | -1.82 | -1.82 |
| 416.46 | 4.03 | 4.03 |
| 324.43 | 2.53 | 2.53 |
| 277.32 | 2.13 | 2.13 |
| 243.31 | 2.84 | 2.84 |
| 411.46 | 5.11 | 5.11 |
| 366.38 | -0.03 | -0.03 |
| 462.80 | 10.63 | 10.63 |
| 296.37 | 1.66 | 1.66 |
| 300.36 | 2.06 | 2.06 |
| 242.26 | 0.11 | 0.11 |
| 295.43 | 3.68 | 3.68 |
| 274.28 | 2.44 | 2.44 |
| 274.32 | 1.00 | 1.00 |
| 453.35 | 5.31 | 5.31 |
| 112.13 | 0.87 | 0.87 |
| 394.68 | 9.23 | 9.23 |
| 208.24 | 1.92 | 1.92 |
| 469.28 | 3.78 | 3.78 |
| 272.30 | 2.18 | 2.18 |
| 231.25 | 1.93 | 1.93 |
| 245.28 | 2.23 | 2.23 |
| 245.28 | 2.23 | 2.23 |
| 437.12 | 3.38 | 3.38 |
| 416.46 | 4.03 | 4.03 |
| 318.33 | -1.00 | -1.00 |
| 296.23 | 0.82 | 0.82 |
| 243.31 | 2.84 | 2.84 |
| 476.83 | 11.02 | 11.02 |
| 409.44 | 1.80 | 1.80 |
| 304.30 | 2.53 | 2.53 |
| 366.38 | 0.26 | 0.26 |
| 400.82 | 0.62 | 0.62 |
| 260.25 | 2.13 | 2.13 |
| 315.37 | 3.18 | 3.18 |
| 290.32 | 0.96 | 0.96 |
| 420.35 | 6.21 | 6.21 |
| 380.40 | 0.56 | 0.56 |
| 348.18 | 2.21 | 2.21 |
| 372.81 | 2.24 | 2.24 |
| 393.40 | 3.23 | 3.23 |
| 521.37 | 2.24 | 2.24 |
| 407.42 | 3.62 | 3.62 |
| 385.42 | 4.60 | 4.60 |
| 284.14 | 3.53 | 3.53 |
| 416.46 | 4.03 | 4.03 |
| 440.41 | 1.02 | 1.02 |