Basic Information
ID: ALA1614483
Type: Functional
Description: PUBCHEM_BIOASSAY: Late stage counterscreen for the probe development effort to identify selective agonists of the Transient Receptor Potential Channels 3 (TRPML3): fluorescence-based cell-based dose response assay for TRPN1 agonists. (Class of assay: confirmatory) [Related pubchem assays: 1682 (Dose Response Counterscreen (TRPN1 agonists, 3X EC50)), 1526 (Confirmation Assay (TRPML3 agonists, 3X %ACT)), 1562 (Dose Response (TRPML3 agonists, 3X EC50)), 1809 (Summary (TRPML3 agonists)), 1525 (Counterscreen Assay (TRPN1 agonists, 3X%ACT)), 1424 (Primary Assay (TRPML3 agonists, 1X%ACT)), 1448 (Counterscreen Assay (TRPN1 agonists, 1X%ACT))]
Organism: Danio rerio
Activity Charts
Bioactivity
Activity Types for Assay ALA1614483
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.89 | 4.71 | 4.71 |
| 319.85 | 3.47 | 3.47 |
| 379.44 | 4.06 | 4.06 |
| 281.42 | 3.23 | 3.23 |
| 297.42 | 2.88 | 2.88 |
| 333.45 | 3.80 | 3.80 |