Basic Information
ID: ALA1614484
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation to Identify Activators of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1829 (Project Summary), 1814 (Primary HTS)]
Activity Charts
Bioactivity
Activity Types for Assay ALA1614484
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.30 | 2.87 | 2.87 |
| 286.32 | 2.75 | 2.75 |
| 346.48 | 4.04 | 4.04 |
| 314.73 | 3.08 | 3.08 |
| 232.28 | 3.47 | 3.47 |
| 501.12 | 7.91 | 7.91 |
| 357.83 | 3.81 | 3.81 |
| 295.41 | 1.89 | 1.89 |
| 290.37 | 2.95 | 2.95 |
| 312.39 | 3.73 | 3.73 |
| 286.29 | 2.84 | 2.84 |
| 313.74 | 4.01 | 4.01 |
| 307.44 | 3.57 | 3.57 |
| 472.59 | 6.21 | 6.21 |
| 273.39 | 3.69 | 3.69 |
| 303.39 | 3.44 | 3.44 |
| 289.36 | 2.53 | 2.53 |
| 370.47 | 4.40 | 4.40 |
| 315.83 | 4.47 | 4.47 |
| 310.42 | 4.04 | 4.04 |
| 309.76 | 3.70 | 3.70 |
| 425.87 | 4.18 | 4.18 |
| 372.45 | 3.40 | 3.40 |
| 277.37 | 2.58 | 2.58 |
| 252.40 | 3.73 | 3.73 |
| 305.29 | 3.79 | 3.79 |
| 334.29 | 3.74 | 3.74 |
| 290.35 | 2.62 | 2.62 |
| 379.46 | 4.52 | 4.52 |
| 265.32 | 3.22 | 3.22 |
| 300.77 | 1.46 | 1.46 |
| 348.45 | 3.42 | 3.42 |
| 316.45 | 4.17 | 4.17 |
| 308.41 | 3.23 | 3.23 |
| 295.30 | 1.96 | 1.96 |
| 269.39 | 1.08 | 1.08 |
| 324.45 | 5.11 | 5.11 |
| 400.59 | 4.28 | 4.28 |
| 316.38 | 3.25 | 3.25 |
| 276.43 | 4.27 | 4.27 |
| 218.69 | 3.15 | 3.15 |
| 367.25 | 5.14 | 5.14 |
| 331.17 | 4.17 | 4.17 |
| 388.27 | 4.77 | 4.77 |
| 292.43 | 3.37 | 3.37 |
| 416.47 | 4.03 | 4.03 |
| 288.39 | 3.45 | 3.45 |
| 304.44 | 3.85 | 3.85 |
| 352.42 | 3.51 | 3.51 |
| 230.31 | 3.17 | 3.17 |
| 473.87 | 3.65 | 3.65 |
| 328.80 | 4.44 | 4.44 |
| 474.41 | 5.39 | 5.39 |
| 308.34 | 2.60 | 2.60 |
| 356.81 | 3.24 | 3.24 |
| 265.27 | 3.80 | 3.80 |
| 270.32 | 3.34 | 3.34 |
| 183.21 | 1.72 | 1.72 |
| 371.46 | 3.38 | 3.38 |
| 395.84 | 4.96 | 4.96 |
| 388.41 | 0.53 | 0.53 |
| 444.60 | 2.69 | 2.69 |
| 204.30 | 2.64 | 2.64 |
| 261.28 | 2.49 | 2.49 |
| 281.31 | 4.09 | 4.09 |
| 312.35 | 2.68 | 2.68 |
| 301.35 | 2.76 | 2.76 |
| 270.31 | 3.96 | 3.96 |
| 326.42 | 4.34 | 4.34 |
| 365.44 | 5.24 | 5.24 |
| 291.42 | 2.60 | 2.60 |
| 278.32 | 2.39 | 2.39 |
| 291.33 | 2.08 | 2.08 |
| 345.44 | 3.01 | 3.01 |
| 423.29 | 3.29 | 3.29 |
| 298.33 | 3.12 | 3.12 |
| 317.77 | 4.05 | 4.05 |
| 273.38 | 2.76 | 2.76 |
| 372.26 | 3.33 | 3.33 |
| 246.29 | 2.47 | 2.47 |
| 297.75 | 3.47 | 3.47 |
| 257.36 | 3.21 | 3.21 |
| 327.41 | 2.77 | 2.77 |
| 318.83 | 4.13 | 4.13 |
| 320.78 | 4.30 | 4.30 |
| 432.43 | 5.00 | 5.00 |
| 479.00 | 2.38 | 2.38 |
| 288.40 | 3.61 | 3.61 |
| 278.36 | 4.01 | 4.01 |
| 287.80 | 3.10 | 3.10 |
| 306.43 | 2.33 | 2.33 |
| 224.27 | 3.01 | 3.01 |
| 314.36 | 2.78 | 2.78 |
| 241.29 | 2.38 | 2.38 |
| 348.24 | 3.94 | 3.94 |
| 333.41 | 1.92 | 1.92 |
| 327.72 | 3.33 | 3.33 |
| 316.45 | 2.97 | 2.97 |
| 261.36 | 3.97 | 3.97 |
| 395.41 | 2.73 | 2.73 |
| 297.18 | 4.21 | 4.21 |
| 309.37 | 3.25 | 3.25 |
| 353.79 | 1.85 | 1.85 |
| 259.70 | 3.01 | 3.01 |
| 251.33 | 4.07 | 4.07 |
| 299.33 | 3.05 | 3.05 |
| 278.31 | 3.90 | 3.90 |
| 340.34 | 3.51 | 3.51 |
| 294.33 | 2.78 | 2.78 |
| 281.41 | 3.64 | 3.64 |
| 350.33 | 3.03 | 3.03 |
| 213.20 | 0.92 | 0.92 |
| 271.36 | 3.22 | 3.22 |
| 429.14 | 4.13 | 4.13 |
| 353.85 | 3.87 | 3.87 |
| 374.49 | 4.39 | 4.39 |
| 278.31 | 2.10 | 2.10 |
| 341.42 | 3.94 | 3.94 |
| 434.57 | 3.23 | 3.23 |
| 330.41 | 3.71 | 3.71 |
| 331.80 | 4.15 | 4.15 |
| 366.44 | 3.70 | 3.70 |
| 330.82 | 3.42 | 3.42 |
| 264.33 | 4.61 | 4.61 |
| 360.80 | 3.27 | 3.27 |
| 271.35 | 3.43 | 3.43 |
| 335.40 | 4.09 | 4.09 |
| 256.33 | 3.04 | 3.04 |
| 336.10 | 3.67 | 3.67 |
| 315.44 | 3.38 | 3.38 |
| 365.84 | 5.32 | 5.32 |
| 318.38 | 3.72 | 3.72 |
| 314.38 | 2.63 | 2.63 |
| 407.31 | 3.47 | 3.47 |
| 222.27 | 1.51 | 1.51 |
| 253.34 | 3.71 | 3.71 |
| 282.41 | 4.61 | 4.61 |
| 358.44 | 4.38 | 4.38 |
| 347.44 | 3.18 | 3.18 |
| 314.75 | 4.62 | 4.62 |
| 275.28 | 3.58 | 3.58 |
| 317.44 | 3.15 | 3.15 |
| 280.33 | 3.93 | 3.93 |
| 283.35 | 3.07 | 3.07 |
| 306.39 | 4.04 | 4.04 |
| 337.38 | 2.16 | 2.16 |
| 333.43 | 3.73 | 3.73 |
| 282.32 | 3.69 | 3.69 |
| 351.83 | 4.85 | 4.85 |
| 408.50 | 5.05 | 5.05 |
| 307.40 | 3.19 | 3.19 |
| 383.27 | 2.47 | 2.47 |
| 339.41 | 2.01 | 2.01 |
| 390.46 | 5.17 | 5.17 |
| 275.38 | 3.08 | 3.08 |
| 397.45 | 2.99 | 2.99 |
| 312.12 | 2.86 | 2.86 |
| 272.26 | 1.81 | 1.81 |
| 308.82 | 4.57 | 4.57 |
| 343.36 | 3.15 | 3.15 |
| 306.46 | 3.65 | 3.65 |
| 271.32 | 3.25 | 3.25 |
| 285.35 | 4.53 | 4.53 |
| 251.29 | 2.98 | 2.98 |
| 315.40 | 2.19 | 2.19 |
| 351.43 | 3.73 | 3.73 |
| 275.33 | 2.92 | 2.92 |
| 301.74 | 3.27 | 3.27 |
| 310.28 | 2.96 | 2.96 |
| 292.36 | 2.98 | 2.98 |
| 358.38 | 3.21 | 3.21 |
| 306.29 | 3.49 | 3.49 |
| 336.35 | 2.64 | 2.64 |
| 273.16 | 3.31 | 3.31 |
| 258.32 | 2.77 | 2.77 |
| 397.50 | 3.23 | 3.23 |
| 295.39 | 3.72 | 3.72 |
| 224.72 | 3.45 | 3.45 |
| 313.31 | 2.58 | 2.58 |
| 235.31 | 2.79 | 2.79 |
| 444.51 | 5.78 | 5.78 |
| 352.25 | 3.72 | 3.72 |
| 283.38 | 3.90 | 3.90 |
| 309.37 | 3.22 | 3.22 |
| 376.82 | 2.68 | 2.68 |
| 344.41 | 2.32 | 2.32 |
| 360.46 | 3.41 | 3.41 |
| 240.72 | 2.17 | 2.17 |
| 442.35 | 4.93 | 4.93 |
| 343.48 | 4.23 | 4.23 |
| 255.32 | 2.95 | 2.95 |
| 296.35 | 3.22 | 3.22 |
| 305.68 | 0.55 | 0.55 |
| 289.40 | 2.47 | 2.47 |
| 409.54 | 4.34 | 4.34 |
| 337.45 | 4.12 | 4.12 |
| 384.48 | 5.19 | 5.19 |
| 291.36 | 2.90 | 2.90 |
| 292.75 | 1.96 | 1.96 |
| 308.38 | 2.85 | 2.85 |
| 389.28 | 3.54 | 3.54 |
| 302.37 | 3.53 | 3.53 |
| 345.20 | 4.22 | 4.22 |
| 335.38 | 4.00 | 4.00 |
| 313.47 | 3.32 | 3.32 |
| 258.25 | 3.41 | 3.41 |
| 283.35 | 4.37 | 4.37 |
| 289.31 | 3.99 | 3.99 |
| 352.23 | 3.91 | 3.91 |
| 332.43 | 2.93 | 2.93 |
| 344.38 | 3.47 | 3.47 |
| 425.45 | 2.11 | 2.11 |
| 375.21 | 5.40 | 5.40 |
| 285.37 | 3.11 | 3.11 |
| 281.24 | 3.25 | 3.25 |
| 266.73 | 2.88 | 2.88 |
| 339.42 | 3.16 | 3.16 |
| 318.38 | 2.91 | 2.91 |
| 336.44 | 2.77 | 2.77 |
| 340.77 | 4.58 | 4.58 |
| 279.37 | 4.41 | 4.41 |
| 330.80 | 3.62 | 3.62 |
| 286.36 | 3.34 | 3.34 |
| 249.27 | 2.28 | 2.28 |
| 337.13 | 2.53 | 2.53 |
| 312.39 | 3.70 | 3.70 |
| 422.53 | 4.74 | 4.74 |
| 251.38 | 2.72 | 2.72 |
| 397.46 | 2.27 | 2.27 |
| 243.27 | 1.79 | 1.79 |
| 298.36 | 3.88 | 3.88 |
| 388.85 | 5.49 | 5.49 |
| 372.45 | 3.32 | 3.32 |
| 317.78 | 2.41 | 2.41 |
| 296.37 | 3.94 | 3.94 |