Basic Information
ID: ALA1614509
Type: Functional
Description: PUBCHEM_BIOASSAY: HTS Image-Based Screen for Selective Antagonists of the KOR Receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1777, AID1778, AID1785, AID1786, AID2284, AID2285, AID2348, AID2352, AID2357, AID2359, AID2370, AID2420, AID2478, AID2491, AID2492, AID2493, AID2495, AID2497, AID2498, AID2500, AID434981, AID449737, AID463105, AID488822, AID488842, AID488935]
Format: BAO_0000019
Organism: Homo sapiens
Target: Kappa opioid receptor(ALA237)
Document: ALA1201862
PubChem Source: AID:2136
Activity Charts
Bioactivity
Activity Types for Assay ALA1614509
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 305.50 | 3.20 | 3.20 |
| 287.10 | 2.77 | 2.77 |
| 270.25 | 1.75 | 1.75 |
| 343.36 | 3.25 | 3.25 |
| 268.35 | 3.65 | 3.65 |
| 340.43 | 4.57 | 4.57 |
| 287.41 | 3.62 | 3.62 |
| 363.84 | 1.30 | 1.30 |
| 214.05 | 3.25 | 3.25 |
| 387.18 | 2.41 | 2.41 |
| 394.46 | 1.97 | 1.97 |
| 400.78 | 3.33 | 3.33 |
| 362.39 | 2.24 | 2.24 |
| 415.90 | 3.92 | 3.92 |
| 273.29 | 3.08 | 3.08 |
| 414.45 | 4.51 | 4.51 |
| 512.20 | 4.89 | 4.89 |
| 317.44 | 3.45 | 3.45 |
| 470.05 | 5.85 | 5.85 |
| 313.29 | 3.14 | 3.14 |
| 324.17 | 2.14 | 2.14 |
| 290.37 | 3.10 | 3.10 |
| 279.78 | 3.86 | 3.86 |
| 279.30 | 4.36 | 4.36 |
| 396.36 | 5.35 | 5.35 |
| 378.52 | 4.40 | 4.40 |
| 440.61 | 3.71 | 3.71 |
| 305.38 | 2.83 | 2.83 |
| 348.49 | 4.31 | 4.31 |
| 340.43 | 3.99 | 3.99 |
| 391.43 | 2.51 | 2.51 |
| 536.10 | 6.56 | 6.56 |
| 373.80 | 4.84 | 4.84 |
| 545.64 | 2.55 | 2.55 |
| 494.66 | 1.81 | 1.81 |
| 474.57 | 1.99 | 1.99 |
| 401.44 | 5.47 | 5.47 |
| 479.65 | 4.11 | 4.11 |
| 347.42 | 3.22 | 3.22 |
| 509.90 | 4.62 | 4.62 |
| 501.65 | 5.90 | 5.90 |
| 442.43 | 5.96 | 5.96 |
| 366.48 | 4.45 | 4.45 |
| 418.49 | 2.06 | 2.06 |
| 290.33 | 5.55 | 5.55 |
| 406.01 | 2.72 | 2.72 |
| 450.54 | 3.62 | 3.62 |
| 286.29 | 2.52 | 2.52 |
| 418.25 | 4.95 | 4.95 |
| 258.39 | 3.64 | 3.64 |
| 309.39 | 1.52 | 1.52 |
| 527.51 | 4.51 | 4.51 |
| 307.31 | 4.13 | 4.13 |
| 363.40 | 4.84 | 4.84 |
| 304.40 | 3.57 | 3.57 |
| 323.83 | 3.40 | 3.40 |
| 285.69 | 3.86 | 3.86 |
| 686.57 | 6.18 | 6.18 |
| 301.78 | 4.26 | 4.26 |
| 468.56 | 2.49 | 2.49 |
| 389.47 | 2.41 | 2.41 |
| 592.64 | 3.00 | 3.00 |
| 307.38 | 2.89 | 2.89 |
| 385.27 | 3.62 | 3.62 |
| 461.55 | 3.03 | 3.03 |
| 329.81 | 4.19 | 4.19 |
| 313.74 | 3.95 | 3.95 |
| 415.45 | 5.86 | 5.86 |
| 228.59 | 1.83 | 1.83 |
| 327.38 | 1.30 | 1.30 |
| 315.35 | 3.35 | 3.35 |
| 364.52 | 3.20 | 3.20 |
| 290.37 | 3.50 | 3.50 |
| 404.29 | 4.37 | 4.37 |
| 397.91 | 4.41 | 4.41 |
| 529.61 | 3.84 | 3.84 |
| 358.44 | 3.63 | 3.63 |
| 287.75 | 2.82 | 2.82 |
| 315.79 | 3.71 | 3.71 |
| 404.43 | 3.12 | 3.12 |
| 409.49 | 4.24 | 4.24 |
| 281.15 | 3.62 | 3.62 |
| 390.30 | 5.65 | 5.65 |
| 224.35 | 2.65 | 2.65 |
| 366.43 | 3.14 | 3.14 |
| 282.68 | 1.92 | 1.92 |
| 288.42 | 3.49 | 3.49 |
| 306.33 | 2.72 | 2.72 |
| 410.48 | 4.85 | 4.85 |
| 325.80 | 4.82 | 4.82 |
| 304.37 | 4.91 | 4.91 |
| 297.31 | 1.76 | 1.76 |
| 315.25 | 1.66 | 1.66 |
| 343.39 | 3.36 | 3.36 |
| 259.70 | 2.50 | 2.50 |
| 241.25 | 1.55 | 1.55 |
| 319.34 | 3.40 | 3.40 |
| 284.28 | 2.06 | 2.06 |
| 328.33 | 2.30 | 2.30 |
| 343.37 | 4.28 | 4.28 |