Basic Information
ID: ALA1614514
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase. (Class of assay: confirmatory) [Related pubchem assays: 518 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614514
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.37 | 2.86 | 2.86 |
| 328.35 | 2.72 | 2.72 |
| 358.38 | 2.06 | 2.06 |
| 497.71 | 2.50 | 2.50 |
| 365.26 | 4.97 | 4.97 |
| 362.90 | 5.04 | 5.04 |
| 376.24 | 3.47 | 3.47 |
| 344.39 | 2.79 | 2.79 |
| 344.32 | 2.60 | 2.60 |
| 345.83 | 3.00 | 3.00 |
| 333.82 | 2.69 | 2.69 |
| 298.77 | 3.66 | 3.66 |
| 339.89 | 3.15 | 3.15 |
| 372.38 | 2.85 | 2.85 |
| 356.70 | 3.74 | 3.74 |
| 301.32 | 2.44 | 2.44 |
| 435.30 | 5.64 | 5.64 |
| 431.83 | 4.08 | 4.08 |
| 385.45 | 3.36 | 3.36 |
| 344.26 | 4.82 | 4.82 |
| 282.23 | 4.22 | 4.22 |
| 236.24 | 1.46 | 1.46 |
| 259.35 | 2.75 | 2.75 |
| 443.50 | 5.51 | 5.51 |
| 276.24 | 1.95 | 1.95 |
| 397.46 | 3.53 | 3.53 |
| 351.16 | 3.78 | 3.78 |
| 260.25 | -0.07 | -0.07 |
| 384.49 | 3.71 | 3.71 |
| 457.32 | 5.56 | 5.56 |
| 289.40 | 3.26 | 3.26 |
| 355.42 | 3.35 | 3.35 |
| 344.46 | 3.81 | 3.81 |
| 433.46 | 1.83 | 1.83 |
| 258.28 | 1.55 | 1.55 |
| 363.69 | 4.80 | 4.80 |
| 373.72 | 3.22 | 3.22 |
| 360.03 | 4.94 | 4.94 |
| 255.71 | 2.82 | 2.82 |
| 361.79 | 4.21 | 4.21 |
| 427.53 | 4.51 | 4.51 |
| 463.32 | 3.90 | 3.90 |
| 503.98 | 4.01 | 4.01 |
| 562.64 | 6.13 | 6.13 |
| 406.46 | 4.77 | 4.77 |
| 337.47 | 3.16 | 3.16 |
| 263.73 | 2.57 | 2.57 |
| 348.84 | 4.61 | 4.61 |
| 319.41 | 3.55 | 3.55 |
| 425.47 | 3.53 | 3.53 |
| 260.36 | 4.40 | 4.40 |
| 395.31 | 6.44 | 6.44 |
| 297.35 | 3.74 | 3.74 |
| 244.25 | 0.88 | 0.88 |
| 362.40 | 4.32 | 4.32 |
| 441.60 | 2.80 | 2.80 |
| 465.60 | 3.08 | 3.08 |
| 332.13 | 4.85 | 4.85 |
| 479.60 | 4.58 | 4.58 |
| 366.25 | 2.75 | 2.75 |
| 366.45 | 4.14 | 4.14 |
| 289.17 | 5.04 | 5.04 |
| 308.34 | 1.85 | 1.85 |
| 323.48 | 3.65 | 3.65 |
| 357.11 | 3.95 | 3.95 |
| 330.52 | 5.10 | 5.10 |
| 286.43 | 4.67 | 4.67 |
| 287.36 | 4.69 | 4.69 |
| 358.94 | 3.37 | 3.37 |
| 358.46 | 2.82 | 2.82 |
| 373.46 | 2.99 | 2.99 |
| 319.43 | 5.01 | 5.01 |
| 309.37 | 3.00 | 3.00 |
| 413.91 | 3.68 | 3.68 |
| 260.32 | 3.18 | 3.18 |
| 528.61 | 7.75 | 7.75 |
| 254.35 | 4.27 | 4.27 |
| 465.60 | 4.96 | 4.96 |
| 401.29 | 4.07 | 4.07 |
| 326.83 | 5.38 | 5.38 |
| 354.91 | 4.94 | 4.94 |
| 292.34 | 4.67 | 4.67 |
| 332.32 | 2.13 | 2.13 |
| 261.33 | 4.57 | 4.57 |
| 329.37 | 5.02 | 5.02 |
| 336.44 | 3.61 | 3.61 |
| 386.45 | 3.66 | 3.66 |
| 336.24 | 5.94 | 5.94 |
| 272.22 | 4.76 | 4.76 |
| 279.30 | 1.34 | 1.34 |
| 327.43 | 5.01 | 5.01 |
| 474.41 | 5.39 | 5.39 |
| 281.83 | 3.26 | 3.26 |
| 494.88 | 6.21 | 6.21 |
| 310.40 | 3.93 | 3.93 |
| 290.35 | 2.53 | 2.53 |
| 497.57 | 2.86 | 2.86 |
| 311.34 | 3.07 | 3.07 |
| 336.83 | 5.15 | 5.15 |
| 444.82 | 5.06 | 5.06 |
| 332.35 | 3.25 | 3.25 |
| 424.48 | 3.86 | 3.86 |
| 293.37 | 3.92 | 3.92 |
| 423.94 | 3.72 | 3.72 |
| 325.43 | 3.20 | 3.20 |
| 272.33 | 1.01 | 1.01 |
| 347.43 | 3.31 | 3.31 |
| 291.76 | 3.75 | 3.75 |
| 326.35 | 2.23 | 2.23 |
| 382.55 | 5.32 | 5.32 |
| 315.29 | 4.03 | 4.03 |
| 247.68 | 0.14 | 0.14 |
| 337.38 | 2.36 | 2.36 |
| 296.40 | 4.35 | 4.35 |
| 320.80 | 4.65 | 4.65 |
| 412.49 | 3.67 | 3.67 |
| 294.31 | 1.93 | 1.93 |
| 450.97 | 3.30 | 3.30 |
| 286.33 | 2.56 | 2.56 |
| 330.23 | 4.41 | 4.41 |
| 328.21 | 4.69 | 4.69 |
| 428.58 | 5.19 | 5.19 |
| 307.40 | 4.12 | 4.12 |
| 333.34 | 4.85 | 4.85 |
| 319.81 | 2.90 | 2.90 |
| 310.35 | 3.26 | 3.26 |
| 407.48 | 6.62 | 6.62 |
| 403.23 | 3.80 | 3.80 |
| 356.81 | 3.52 | 3.52 |
| 472.54 | 5.46 | 5.46 |
| 333.76 | 3.38 | 3.38 |
| 428.49 | 3.68 | 3.68 |
| 238.33 | 3.39 | 3.39 |
| 383.54 | 4.27 | 4.27 |
| 269.37 | 4.06 | 4.06 |
| 255.27 | 3.44 | 3.44 |
| 419.39 | 2.20 | 2.20 |
| 381.24 | 3.99 | 3.99 |
| 363.49 | 3.49 | 3.49 |
| 366.51 | 4.71 | 4.71 |
| 229.28 | 2.63 | 2.63 |
| 355.46 | 4.35 | 4.35 |
| 384.49 | 4.35 | 4.35 |
| 239.38 | 3.69 | 3.69 |
| 378.23 | 3.59 | 3.59 |
| 409.47 | 3.33 | 3.33 |
| 491.57 | 4.84 | 4.84 |
| 329.83 | 3.37 | 3.37 |
| 266.77 | 4.10 | 4.10 |
| 407.55 | 3.66 | 3.66 |
| 396.90 | 5.57 | 5.57 |
| 430.32 | 6.18 | 6.18 |
| 402.50 | 5.04 | 5.04 |
| 355.58 | 4.32 | 4.32 |
| 349.39 | 4.63 | 4.63 |
| 327.34 | 3.56 | 3.56 |
| 358.35 | 1.50 | 1.50 |
| 343.50 | 2.97 | 2.97 |
| 317.35 | 2.51 | 2.51 |
| 299.44 | 4.42 | 4.42 |
| 463.32 | 3.90 | 3.90 |
| 432.55 | 4.22 | 4.22 |
| 399.63 | 5.40 | 5.40 |
| 547.67 | 3.17 | 3.17 |
| 293.33 | 2.38 | 2.38 |
| 498.32 | 6.16 | 6.16 |
| 321.25 | 4.32 | 4.32 |
| 289.29 | 2.20 | 2.20 |
| 326.36 | 2.29 | 2.29 |
| 357.37 | 4.90 | 4.90 |
| 318.38 | 3.72 | 3.72 |
| 283.76 | 4.58 | 4.58 |
| 485.02 | 6.34 | 6.34 |
| 445.79 | 2.78 | 2.78 |
| 458.59 | 4.59 | 4.59 |
| 468.63 | 5.18 | 5.18 |
| 412.39 | 4.56 | 4.56 |
| 259.29 | 2.35 | 2.35 |
| 340.69 | 2.27 | 2.27 |
| 332.37 | 2.81 | 2.81 |
| 457.58 | 3.13 | 3.13 |
| 319.39 | 1.53 | 1.53 |
| 480.85 | 5.90 | 5.90 |
| 358.90 | 3.97 | 3.97 |
| 474.57 | 6.11 | 6.11 |
| 322.75 | 3.75 | 3.75 |
| 439.94 | 3.42 | 3.42 |
| 314.33 | 2.31 | 2.31 |
| 366.27 | 5.28 | 5.28 |
| 353.73 | 5.02 | 5.02 |
| 380.50 | 5.63 | 5.63 |
| 424.50 | 3.09 | 3.09 |
| 470.60 | 4.69 | 4.69 |
| 339.89 | 3.94 | 3.94 |
| 464.01 | 4.71 | 4.71 |
| 252.75 | 1.60 | 1.60 |
| 257.38 | 4.40 | 4.40 |
| 262.27 | 2.97 | 2.97 |
| 344.21 | 4.70 | 4.70 |
| 452.61 | 5.39 | 5.39 |
| 306.32 | 1.78 | 1.78 |
| 394.56 | 4.59 | 4.59 |
| 242.37 | 3.95 | 3.95 |
| 358.45 | 3.03 | 3.03 |
| 337.33 | 2.88 | 2.88 |
| 322.36 | 4.16 | 4.16 |
| 274.35 | 4.28 | 4.28 |
| 355.42 | 1.84 | 1.84 |
| 329.32 | 4.42 | 4.42 |
| 264.22 | 2.07 | 2.07 |
| 315.35 | 4.71 | 4.71 |
| 279.39 | 4.35 | 4.35 |
| 291.10 | 1.11 | 1.11 |
| 397.89 | 5.01 | 5.01 |
| 362.48 | 3.46 | 3.46 |
| 488.29 | 6.12 | 6.12 |
| 416.53 | 5.43 | 5.43 |
| 307.31 | 1.18 | 1.18 |
| 333.42 | 4.62 | 4.62 |
| 455.56 | 4.52 | 4.52 |
| 318.21 | 5.23 | 5.23 |
| 315.35 | 4.71 | 4.71 |
| 269.77 | 2.12 | 2.12 |
| 378.27 | 4.16 | 4.16 |
| 365.46 | 4.14 | 4.14 |
| 382.44 | 3.62 | 3.62 |
| 503.19 | 3.38 | 3.38 |
| 351.45 | 2.84 | 2.84 |
| 392.25 | 4.07 | 4.07 |
| 408.76 | 2.88 | 2.88 |
| 265.25 | 0.65 | 0.65 |
| 203.20 | 1.50 | 1.50 |
| 364.49 | 3.56 | 3.56 |
| 427.55 | 4.90 | 4.90 |
| 311.77 | 4.88 | 4.88 |
| 384.44 | 3.64 | 3.64 |
| 358.42 | 2.99 | 2.99 |
| 270.29 | 3.01 | 3.01 |
| 491.39 | 4.64 | 4.64 |
| 343.41 | 3.41 | 3.41 |
| 334.34 | 2.44 | 2.44 |
| 399.50 | 4.11 | 4.11 |
| 430.55 | 4.00 | 4.00 |
| 292.30 | 3.48 | 3.48 |
| 344.25 | 4.50 | 4.50 |
| 275.70 | 3.69 | 3.69 |
| 267.29 | 2.83 | 2.83 |
| 346.37 | 1.07 | 1.07 |
| 469.58 | 3.39 | 3.39 |
| 455.56 | 3.15 | 3.15 |
| 413.53 | 4.60 | 4.60 |
| 413.53 | 4.60 | 4.60 |
| 282.34 | 2.78 | 2.78 |
| 318.47 | 3.75 | 3.75 |