Basic Information
ID: ALA1614515
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease: Primary Screen Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 2101 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614515
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.46 | 4.18 | 4.18 |
| 407.99 | 4.46 | 4.46 |
| 311.39 | 4.91 | 4.91 |
| 556.36 | 5.37 | 5.37 |
| 163.17 | -2.97 | -2.97 |
| 317.42 | 4.97 | 4.97 |
| 256.26 | 2.70 | 2.70 |
| 542.33 | 4.98 | 4.98 |
| 147.17 | -2.08 | -2.08 |
| 435.89 | 2.99 | 2.99 |
| 361.47 | 5.00 | 5.00 |
| 323.40 | 4.22 | 4.22 |
| 490.65 | 4.75 | 4.75 |
| 515.46 | 4.63 | 4.63 |
| 458.54 | 4.09 | 4.09 |
| 501.50 | 4.10 | 4.10 |
| 520.68 | 4.97 | 4.97 |
| 442.59 | 3.93 | 3.93 |
| 486.64 | 5.11 | 5.11 |
| 521.07 | 5.68 | 5.68 |
| 434.52 | 3.71 | 3.71 |
| 487.47 | 4.06 | 4.06 |
| 449.60 | 4.78 | 4.78 |
| 454.55 | 4.01 | 4.01 |
| 460.56 | 3.82 | 3.82 |
| 455.54 | 3.68 | 3.68 |
| 520.56 | 4.77 | 4.77 |
| 437.55 | 3.26 | 3.26 |
| 451.58 | 3.57 | 3.57 |
| 351.16 | 3.37 | 3.37 |
| 490.97 | 3.61 | 3.61 |
| 541.92 | 4.18 | 4.18 |
| 347.24 | 3.36 | 3.36 |
| 245.26 | 3.17 | 3.17 |
| 468.46 | 2.05 | 2.05 |
| 306.16 | 3.80 | 3.80 |
| 436.56 | 3.87 | 3.87 |
| 521.39 | 3.41 | 3.41 |
| 324.45 | 3.50 | 3.50 |
| 471.01 | 4.52 | 4.52 |
| 255.32 | 3.65 | 3.65 |
| 471.01 | 4.52 | 4.52 |
| 515.46 | 4.63 | 4.63 |
| 398.53 | 4.66 | 4.66 |
| 521.92 | 4.71 | 4.71 |
| 505.45 | 5.18 | 5.18 |
| 462.57 | 2.70 | 2.70 |
| 396.52 | 4.42 | 4.42 |
| 493.64 | 4.48 | 4.48 |
| 498.53 | 4.83 | 4.83 |
| 229.12 | 2.69 | 2.69 |
| 472.54 | 4.15 | 4.15 |
| 466.63 | 4.81 | 4.81 |
| 471.01 | 4.52 | 4.52 |
| 535.94 | 5.06 | 5.06 |
| 400.53 | 3.02 | 3.02 |
| 518.64 | 4.61 | 4.61 |
| 464.98 | 4.46 | 4.46 |
| 514.53 | 4.71 | 4.71 |
| 355.46 | 4.36 | 4.36 |
| 591.35 | 5.61 | 5.61 |
| 450.59 | 4.18 | 4.18 |
| 307.38 | 4.56 | 4.56 |
| 464.98 | 4.46 | 4.46 |
| 444.56 | 4.12 | 4.12 |
| 453.45 | 3.66 | 3.66 |
| 478.60 | 4.07 | 4.07 |
| 428.51 | 2.48 | 2.48 |
| 486.62 | 5.02 | 5.02 |
| 510.49 | 3.67 | 3.67 |
| 357.84 | 3.66 | 3.66 |
| 357.89 | 4.52 | 4.52 |
| 499.42 | 5.11 | 5.11 |
| 488.57 | 3.58 | 3.58 |
| 281.38 | 4.13 | 4.13 |
| 361.88 | 4.59 | 4.59 |
| 271.35 | 2.76 | 2.76 |
| 482.97 | 4.60 | 4.60 |
| 478.57 | 2.63 | 2.63 |
| 489.56 | 2.97 | 2.97 |
| 358.39 | 4.74 | 4.74 |
| 472.52 | 2.74 | 2.74 |
| 450.52 | 1.85 | 1.85 |
| 492.67 | 5.17 | 5.17 |
| 445.55 | 3.51 | 3.51 |
| 475.53 | 3.72 | 3.72 |
| 448.52 | 3.95 | 3.95 |
| 496.61 | 3.89 | 3.89 |
| 512.91 | 3.88 | 3.88 |
| 454.55 | 4.01 | 4.01 |
| 389.12 | 4.51 | 4.51 |
| 449.60 | 5.11 | 5.11 |
| 428.58 | 3.64 | 3.64 |
| 470.87 | 3.71 | 3.71 |
| 508.63 | 4.05 | 4.05 |
| 481.56 | 3.78 | 3.78 |
| 450.59 | 4.18 | 4.18 |
| 502.60 | 3.98 | 3.98 |
| 445.55 | 3.51 | 3.51 |
| 478.60 | 4.07 | 4.07 |
| 464.62 | 4.49 | 4.49 |
| 450.59 | 4.18 | 4.18 |
| 402.55 | 3.22 | 3.22 |
| 466.59 | 3.88 | 3.88 |
| 432.45 | 2.78 | 2.78 |
| 333.39 | 4.61 | 4.61 |
| 472.52 | 2.02 | 2.02 |
| 330.34 | 3.79 | 3.79 |
| 470.55 | 3.21 | 3.21 |
| 273.36 | 3.76 | 3.76 |
| 295.77 | 4.41 | 4.41 |
| 241.29 | 3.34 | 3.34 |
| 327.39 | 5.05 | 5.05 |
| 349.43 | 4.30 | 4.30 |
| 318.41 | 4.37 | 4.37 |
| 411.60 | 4.88 | 4.88 |
| 501.51 | 5.07 | 5.07 |
| 310.43 | 3.11 | 3.11 |
| 333.39 | 4.37 | 4.37 |
| 335.19 | 3.91 | 3.91 |
| 402.52 | 4.69 | 4.69 |
| 338.44 | 3.03 | 3.03 |
| 456.57 | 4.42 | 4.42 |
| 745.82 | 10.08 | 10.08 |
| 480.59 | 4.96 | 4.96 |
| 461.57 | 3.74 | 3.74 |
| 535.94 | 5.10 | 5.10 |
| 446.54 | 2.91 | 2.91 |
| 374.49 | 2.44 | 2.44 |
| 542.33 | 4.98 | 4.98 |
| 464.98 | 4.46 | 4.46 |
| 522.90 | 4.11 | 4.11 |
| 472.57 | 4.01 | 4.01 |
| 494.60 | 3.64 | 3.64 |
| 548.74 | 3.58 | 3.58 |
| 446.54 | 2.91 | 2.91 |
| 515.46 | 4.63 | 4.63 |
| 461.57 | 3.74 | 3.74 |
| 410.50 | 2.65 | 2.65 |
| 394.50 | 3.02 | 3.02 |
| 464.62 | 4.49 | 4.49 |
| 368.46 | 2.45 | 2.45 |
| 446.54 | 2.91 | 2.91 |
| 504.56 | 4.89 | 4.89 |
| 505.85 | 4.55 | 4.55 |
| 543.92 | 5.43 | 5.43 |
| 484.63 | 4.69 | 4.69 |
| 487.61 | 4.42 | 4.42 |
| 474.59 | 4.21 | 4.21 |
| 311.41 | 3.95 | 3.95 |
| 535.94 | 4.76 | 4.76 |
| 343.86 | 4.14 | 4.14 |
| 462.57 | 2.85 | 2.85 |
| 543.87 | 5.22 | 5.22 |
| 400.51 | 4.61 | 4.61 |
| 584.17 | 5.40 | 5.40 |
| 390.49 | 4.82 | 4.82 |
| 474.59 | 4.12 | 4.12 |
| 437.55 | 4.25 | 4.25 |
| 395.71 | 5.46 | 5.46 |
| 296.28 | 3.02 | 3.02 |
| 449.30 | 3.15 | 3.15 |
| 457.56 | 3.81 | 3.81 |
| 470.55 | 3.26 | 3.26 |
| 355.40 | 0.25 | 0.25 |
| 298.27 | 3.01 | 3.01 |
| 343.41 | 5.61 | 5.61 |
| 400.51 | 4.32 | 4.32 |
| 504.56 | 4.89 | 4.89 |
| 375.10 | 4.12 | 4.12 |
| 486.62 | 5.02 | 5.02 |
| 448.55 | 2.85 | 2.85 |
| 480.57 | 3.60 | 3.60 |
| 451.58 | 3.57 | 3.57 |
| 478.60 | 4.07 | 4.07 |
| 354.68 | 3.85 | 3.85 |
| 461.57 | 3.74 | 3.74 |
| 540.29 | 5.20 | 5.20 |
| 450.59 | 4.01 | 4.01 |
| 498.53 | 4.83 | 4.83 |
| 451.58 | 3.57 | 3.57 |
| 451.58 | 3.57 | 3.57 |
| 463.44 | 2.02 | 2.02 |
| 481.56 | 3.78 | 3.78 |
| 465.50 | 3.85 | 3.85 |
| 227.27 | 3.03 | 3.03 |
| 414.34 | 5.26 | 5.26 |
| 384.27 | 5.40 | 5.40 |
| 271.32 | 3.43 | 3.43 |
| 331.40 | 1.98 | 1.98 |
| 422.32 | 6.50 | 6.50 |
| 397.43 | 4.12 | 4.12 |
| 463.33 | 3.54 | 3.54 |
| 257.29 | 3.04 | 3.04 |
| 424.46 | 5.51 | 5.51 |
| 388.47 | 3.99 | 3.99 |
| 464.62 | 4.57 | 4.57 |
| 509.43 | 4.57 | 4.57 |
| 549.72 | 4.01 | 4.01 |
| 492.67 | 5.17 | 5.17 |
| 335.35 | 4.84 | 4.84 |
| 498.53 | 4.83 | 4.83 |
| 443.58 | 3.33 | 3.33 |
| 442.59 | 3.93 | 3.93 |
| 470.60 | 4.30 | 4.30 |
| 246.23 | 0.43 | 0.43 |
| 454.55 | 4.01 | 4.01 |
| 509.43 | 4.57 | 4.57 |
| 497.62 | 4.44 | 4.44 |
| 517.63 | 4.57 | 4.57 |
| 452.62 | 4.11 | 4.11 |
| 275.36 | 4.50 | 4.50 |
| 472.52 | 2.60 | 2.60 |
| 245.26 | 3.17 | 3.17 |
| 483.41 | 3.99 | 3.99 |
| 388.50 | 4.39 | 4.39 |
| 477.47 | 4.61 | 4.61 |
| 507.64 | 3.70 | 3.70 |
| 466.59 | 3.88 | 3.88 |
| 508.63 | 4.05 | 4.05 |
| 481.56 | 3.78 | 3.78 |
| 504.56 | 4.89 | 4.89 |
| 444.56 | 4.45 | 4.45 |
| 426.50 | 2.24 | 2.24 |
| 452.61 | 4.42 | 4.42 |
| 466.59 | 3.88 | 3.88 |
| 449.60 | 4.78 | 4.78 |
| 475.53 | 3.72 | 3.72 |
| 451.64 | 4.37 | 4.37 |
| 460.56 | 3.82 | 3.82 |
| 455.54 | 3.68 | 3.68 |
| 211.22 | 2.33 | 2.33 |
| 418.52 | 4.95 | 4.95 |
| 307.37 | 4.79 | 4.79 |
| 394.86 | 4.92 | 4.92 |
| 255.32 | 3.65 | 3.65 |
| 474.51 | 4.53 | 4.53 |
| 272.30 | 2.91 | 2.91 |
| 384.50 | 4.10 | 4.10 |
| 446.57 | 4.95 | 4.95 |
| 333.42 | 5.11 | 5.11 |
| 338.48 | 3.89 | 3.89 |
| 429.30 | 5.57 | 5.57 |
| 255.32 | 3.65 | 3.65 |
| 320.23 | 3.20 | 3.20 |
| 428.46 | 3.33 | 3.33 |
| 487.61 | 4.42 | 4.42 |
| 519.12 | 5.62 | 5.62 |
| 464.62 | 4.49 | 4.49 |
| 478.55 | 3.96 | 3.96 |
| 397.35 | 2.47 | 2.47 |
| 435.51 | 3.10 | 3.10 |
| 519.12 | 5.62 | 5.62 |
| 535.94 | 5.06 | 5.06 |
| 520.93 | 5.32 | 5.32 |
| 475.53 | 3.72 | 3.72 |
| 379.83 | 1.52 | 1.52 |
| 280.28 | 3.32 | 3.32 |
| 261.71 | 3.69 | 3.69 |
| 474.57 | 5.58 | 5.58 |
| 509.61 | 2.46 | 2.46 |
| 515.64 | 2.52 | 2.52 |
| 394.46 | 3.28 | 3.28 |
| 411.49 | 1.55 | 1.55 |
| 440.55 | 2.90 | 2.90 |
| 1246.66 | ||
| 1306.78 | ||
| 311.41 | 3.86 | 3.86 |
| 313.40 | 2.99 | 2.99 |
| 315.39 | 3.43 | 3.43 |
| 312.42 | 2.99 | 2.99 |
| 530.44 | 4.90 | 4.90 |