Basic Information
ID: ALA1614547
Type: Binding
Description: PUBCHEM_BIOASSAY: HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate. (Class of assay: confirmatory) [Related pubchem assays: 1209 ]
Format: BAO_0000357
Organism: Homo sapiens
Target: Mannose-6-phosphate isomerase(ALA2758)
Document: ALA1201862
PubChem Source: AID:1220
Activity Charts
Bioactivity
Activity Types for Assay ALA1614547
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.29 | 3.28 | 3.28 |
| 346.86 | 4.57 | 4.57 |
| 458.50 | 2.18 | 2.18 |
| 345.36 | -1.07 | -1.07 |
| 163.15 | 2.08 | 2.08 |
| 397.54 | 2.86 | 2.86 |
| 293.37 | 2.71 | 2.71 |
| 364.42 | 3.20 | 3.20 |
| 374.83 | 3.03 | 3.03 |
| 340.40 | 5.43 | 5.43 |
| 271.30 | 3.22 | 3.22 |
| 463.32 | 3.90 | 3.90 |
| 392.51 | 4.88 | 4.88 |
| 475.61 | 4.30 | 4.30 |
| 358.44 | 5.07 | 5.07 |
| 350.44 | 5.24 | 5.24 |
| 333.24 | 3.13 | 3.13 |
| 380.36 | 0.81 | 0.81 |
| 363.42 | 3.02 | 3.02 |
| 389.51 | 3.15 | 3.15 |
| 229.33 | 3.70 | 3.70 |
| 303.79 | 2.85 | 2.85 |
| 337.38 | 1.87 | 1.87 |
| 296.37 | 4.79 | 4.79 |
| 458.45 | 3.57 | 3.57 |
| 410.74 | 4.54 | 4.54 |
| 158.20 | 2.13 | 2.13 |
| 229.24 | 2.29 | 2.29 |
| 412.49 | 3.57 | 3.57 |
| 252.21 | 2.02 | 2.02 |
| 542.39 | 5.34 | 5.34 |
| 243.31 | 2.38 | 2.38 |
| 292.38 | 3.96 | 3.96 |
| 357.40 | 4.09 | 4.09 |
| 218.08 | 3.06 | 3.06 |
| 376.51 | 5.18 | 5.18 |
| 375.45 | 2.36 | 2.36 |
| 147.18 | 1.16 | 1.16 |
| 341.21 | 2.94 | 2.94 |
| 360.89 | 4.96 | 4.96 |
| 247.68 | 0.14 | 0.14 |
| 314.35 | 0.90 | 0.90 |
| 354.50 | 4.52 | 4.52 |
| 361.40 | 4.27 | 4.27 |
| 369.38 | 3.52 | 3.52 |
| 276.30 | 0.92 | 0.92 |
| 369.49 | 2.70 | 2.70 |
| 265.27 | 1.83 | 1.83 |
| 202.21 | 1.50 | 1.50 |
| 409.41 | 4.30 | 4.30 |
| 220.27 | 4.21 | 4.21 |
| 352.43 | 4.94 | 4.94 |
| 323.42 | 4.66 | 4.66 |
| 338.42 | 2.37 | 2.37 |
| 325.36 | 2.65 | 2.65 |
| 380.81 | 3.73 | 3.73 |
| 358.35 | 1.50 | 1.50 |
| 231.29 | 1.63 | 1.63 |
| 432.48 | 5.11 | 5.11 |
| 375.40 | 3.07 | 3.07 |
| 259.26 | 2.42 | 2.42 |
| 298.34 | 3.90 | 3.90 |
| 377.42 | 2.97 | 2.97 |
| 310.31 | 3.55 | 3.55 |
| 331.71 | 3.61 | 3.61 |
| 305.21 | 2.55 | 2.55 |
| 432.91 | 3.84 | 3.84 |
| 253.35 | 3.24 | 3.24 |
| 277.28 | 2.99 | 2.99 |
| 383.52 | 4.54 | 4.54 |
| 205.26 | 2.70 | 2.70 |
| 392.46 | 3.20 | 3.20 |
| 294.31 | 2.91 | 2.91 |
| 223.28 | 2.97 | 2.97 |
| 351.45 | 2.35 | 2.35 |
| 383.88 | 5.64 | 5.64 |
| 366.42 | 2.53 | 2.53 |
| 197.24 | 2.82 | 2.82 |
| 532.46 | 5.36 | 5.36 |
| 307.63 | 3.85 | 3.85 |
| 253.74 | 2.96 | 2.96 |
| 323.23 | 3.76 | 3.76 |
| 384.44 | 1.30 | 1.30 |
| 415.47 | 3.38 | 3.38 |
| 375.41 | 2.36 | 2.36 |
| 400.44 | 1.01 | 1.01 |
| 319.38 | 2.86 | 2.86 |
| 322.41 | 1.56 | 1.56 |
| 332.41 | 3.46 | 3.46 |
| 388.36 | 2.25 | 2.25 |
| 279.32 | 1.39 | 1.39 |
| 407.45 | 1.60 | 1.60 |
| 282.30 | 2.98 | 2.98 |
| 293.35 | 1.78 | 1.78 |
| 270.24 | 3.07 | 3.07 |
| 381.43 | 4.37 | 4.37 |
| 378.41 | 0.79 | 0.79 |
| 333.39 | 4.05 | 4.05 |
| 231.32 | 3.82 | 3.82 |
| 319.36 | 3.66 | 3.66 |