Basic Information
ID: ALA1614547
Type: Binding
Description: PUBCHEM_BIOASSAY: HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate. (Class of assay: confirmatory) [Related pubchem assays: 1209 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614547
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.47 | 2.32 | 2.32 |
| 187.20 | 1.02 | 1.02 |
| 292.14 | 1.76 | 1.76 |
| 274.18 | ||
| 258.75 | 3.10 | 3.10 |
| 144.18 | 1.82 | 1.82 |
| 272.31 | 3.66 | 3.66 |
| 220.31 | 3.08 | 3.08 |
| 144.18 | 1.82 | 1.82 |
| 178.14 | 1.20 | 1.20 |
| 270.29 | 3.28 | 3.28 |
| 464.38 | 0.19 | 0.19 |
| 412.44 | 3.96 | 3.96 |
| 346.86 | 4.57 | 4.57 |
| 233.27 | 2.42 | 2.42 |
| 458.50 | 2.18 | 2.18 |
| 282.30 | 3.10 | 3.10 |
| 366.39 | 3.47 | 3.47 |
| 252.36 | 3.84 | 3.84 |
| 207.19 | -1.32 | -1.32 |
| 321.22 | 3.69 | 3.69 |
| 243.29 | 2.15 | 2.15 |
| 321.80 | 2.85 | 2.85 |
| 361.35 | 1.13 | 1.13 |
| 345.36 | -1.07 | -1.07 |
| 163.15 | 2.08 | 2.08 |
| 397.54 | 2.86 | 2.86 |
| 413.52 | 3.53 | 3.53 |
| 337.17 | 2.43 | 2.43 |
| 426.47 | 4.65 | 4.65 |
| 409.49 | 1.70 | 1.70 |
| 427.75 | 3.98 | 3.98 |
| 349.43 | 3.27 | 3.27 |
| 325.37 | 2.03 | 2.03 |
| 254.68 | 1.29 | 1.29 |
| 488.57 | 5.37 | 5.37 |
| 222.25 | 2.97 | 2.97 |
| 239.32 | 2.84 | 2.84 |
| 355.44 | 3.35 | 3.35 |
| 336.34 | 3.09 | 3.09 |
| 259.31 | 3.50 | 3.50 |
| 329.26 | 2.52 | 2.52 |
| 310.28 | 3.60 | 3.60 |
| 316.31 | 1.78 | 1.78 |
| 280.37 | 3.72 | 3.72 |
| 306.27 | 2.00 | 2.00 |
| 217.27 | 0.55 | 0.55 |
| 293.37 | 2.71 | 2.71 |
| 348.31 | 1.76 | 1.76 |
| 276.31 | 4.66 | 4.66 |
| 326.44 | 4.31 | 4.31 |
| 244.69 | 2.66 | 2.66 |
| 296.41 | 4.30 | 4.30 |
| 291.35 | 3.69 | 3.69 |
| 490.57 | 3.15 | 3.15 |
| 235.25 | -0.67 | -0.67 |
| 476.52 | 1.67 | 1.67 |
| 218.32 | 2.90 | 2.90 |
| 313.40 | 3.32 | 3.32 |
| 178.19 | 0.87 | 0.87 |
| 302.29 | 3.56 | 3.56 |
| 364.42 | 3.20 | 3.20 |
| 374.83 | 3.03 | 3.03 |
| 238.29 | 2.62 | 2.62 |
| 314.37 | 3.37 | 3.37 |
| 420.47 | 4.80 | 4.80 |
| 398.47 | 3.62 | 3.62 |
| 268.35 | 2.68 | 2.68 |
| 327.29 | 3.86 | 3.86 |
| 241.32 | 3.36 | 3.36 |
| 357.46 | 5.04 | 5.04 |
| 240.22 | 3.45 | 3.45 |
| 334.42 | 2.30 | 2.30 |
| 340.40 | 5.43 | 5.43 |
| 271.30 | 3.22 | 3.22 |
| 463.32 | 3.90 | 3.90 |
| 392.51 | 4.88 | 4.88 |
| 475.61 | 4.30 | 4.30 |
| 358.44 | 5.07 | 5.07 |
| 412.42 | 2.54 | 2.54 |
| 269.26 | 3.08 | 3.08 |
| 326.36 | 2.19 | 2.19 |
| 276.30 | 3.52 | 3.52 |
| 427.55 | 3.92 | 3.92 |
| 237.30 | 3.24 | 3.24 |
| 265.42 | 1.66 | 1.66 |
| 264.28 | 1.56 | 1.56 |
| 412.31 | 3.29 | 3.29 |
| 451.12 | 3.70 | 3.70 |
| 297.27 | 1.00 | 1.00 |
| 440.50 | 4.05 | 4.05 |
| 397.34 | 2.28 | 2.28 |
| 318.38 | 2.09 | 2.09 |
| 350.44 | 5.24 | 5.24 |
| 333.24 | 3.13 | 3.13 |
| 380.36 | 0.81 | 0.81 |
| 363.42 | 3.02 | 3.02 |
| 352.39 | 3.26 | 3.26 |
| 289.36 | 3.13 | 3.13 |
| 333.19 | 3.08 | 3.08 |
| 361.47 | 2.80 | 2.80 |
| 291.33 | 2.22 | 2.22 |
| 402.45 | 4.82 | 4.82 |
| 369.43 | 4.68 | 4.68 |
| 340.42 | 4.76 | 4.76 |
| 365.43 | 2.70 | 2.70 |
| 347.39 | 4.39 | 4.39 |
| 354.39 | 1.53 | 1.53 |
| 236.73 | 3.47 | 3.47 |
| 389.51 | 3.15 | 3.15 |
| 229.33 | 3.70 | 3.70 |
| 303.79 | 2.85 | 2.85 |
| 337.38 | 1.87 | 1.87 |
| 296.37 | 4.79 | 4.79 |
| 458.45 | 3.57 | 3.57 |
| 314.18 | 2.17 | 2.17 |
| 212.64 | 0.71 | 0.71 |
| 348.27 | 2.98 | 2.98 |
| 208.26 | 3.51 | 3.51 |
| 406.51 | 3.96 | 3.96 |
| 252.30 | 0.87 | 0.87 |
| 258.32 | 4.52 | 4.52 |
| 280.35 | 1.89 | 1.89 |
| 234.31 | 2.51 | 2.51 |
| 538.66 | ||
| 412.29 | 3.66 | 3.66 |
| 327.45 | 4.87 | 4.87 |
| 410.74 | 4.54 | 4.54 |
| 158.20 | 2.13 | 2.13 |
| 229.24 | 2.29 | 2.29 |
| 412.49 | 3.57 | 3.57 |
| 252.21 | 2.02 | 2.02 |
| 542.39 | 5.34 | 5.34 |
| 293.40 | 4.57 | 4.57 |
| 306.37 | 3.41 | 3.41 |
| 390.78 | 3.94 | 3.94 |
| 262.22 | 0.60 | 0.60 |
| 243.31 | 2.38 | 2.38 |
| 306.32 | 0.28 | 0.28 |
| 292.38 | 3.96 | 3.96 |
| 357.40 | 4.09 | 4.09 |
| 218.08 | 3.06 | 3.06 |
| 250.30 | 3.55 | 3.55 |
| 288.39 | 3.31 | 3.31 |
| 320.40 | 2.61 | 2.61 |
| 405.54 | 5.08 | 5.08 |
| 352.46 | 4.31 | 4.31 |
| 355.87 | 2.32 | 2.32 |
| 433.39 | 5.52 | 5.52 |
| 377.22 | 1.35 | 1.35 |
| 426.30 | 4.17 | 4.17 |
| 232.28 | 2.34 | 2.34 |
| 355.44 | 2.73 | 2.73 |
| 354.44 | 2.09 | 2.09 |
| 376.51 | 5.18 | 5.18 |
| 375.45 | 2.36 | 2.36 |
| 147.18 | 1.16 | 1.16 |
| 350.76 | 4.52 | 4.52 |
| 291.35 | 4.14 | 4.14 |
| 466.54 | 3.17 | 3.17 |
| 396.44 | 4.28 | 4.28 |
| 325.37 | 3.45 | 3.45 |
| 388.51 | 3.54 | 3.54 |
| 462.53 | 4.19 | 4.19 |
| 261.24 | 2.11 | 2.11 |
| 433.33 | 2.77 | 2.77 |
| 310.38 | 3.67 | 3.67 |
| 327.34 | 1.64 | 1.64 |
| 323.40 | 2.72 | 2.72 |
| 424.50 | 3.66 | 3.66 |
| 371.28 | 4.73 | 4.73 |
| 212.25 | 2.40 | 2.40 |
| 497.65 | 3.34 | 3.34 |
| 393.52 | 4.35 | 4.35 |
| 341.21 | 2.94 | 2.94 |
| 360.89 | 4.96 | 4.96 |
| 247.68 | 0.14 | 0.14 |
| 344.42 | 2.62 | 2.62 |
| 390.53 | 3.66 | 3.66 |
| 412.49 | 2.89 | 2.89 |
| 290.37 | 3.89 | 3.89 |
| 510.69 | 5.74 | 5.74 |
| 232.31 | 2.50 | 2.50 |
| 314.35 | 0.90 | 0.90 |
| 354.50 | 4.52 | 4.52 |
| 361.40 | 4.27 | 4.27 |
| 356.42 | 3.02 | 3.02 |
| 326.78 | 3.69 | 3.69 |
| 337.24 | 4.68 | 4.68 |
| 492.51 | 4.08 | 4.08 |
| 294.27 | 2.77 | 2.77 |
| 279.39 | 2.57 | 2.57 |
| 262.19 | -0.33 | -0.33 |
| 312.38 | 2.05 | 2.05 |
| 369.38 | 3.52 | 3.52 |
| 276.30 | 0.92 | 0.92 |
| 369.49 | 2.70 | 2.70 |
| 265.27 | 1.83 | 1.83 |
| 278.36 | 4.17 | 4.17 |
| 325.37 | 3.65 | 3.65 |
| 232.33 | 2.76 | 2.76 |
| 340.41 | 1.41 | 1.41 |
| 384.40 | -1.24 | -1.24 |
| 406.44 | 4.41 | 4.41 |
| 473.58 | 2.48 | 2.48 |
| 337.42 | 4.42 | 4.42 |
| 241.72 | 1.43 | 1.43 |
| 383.56 | 4.60 | 4.60 |
| 289.32 | 2.85 | 2.85 |
| 316.31 | 3.87 | 3.87 |
| 190.29 | 3.01 | 3.01 |
| 396.47 | 2.78 | 2.78 |
| 333.44 | 3.15 | 3.15 |
| 342.46 | 3.15 | 3.15 |
| 227.27 | 1.30 | 1.30 |
| 325.41 | 3.34 | 3.34 |
| 202.21 | 1.50 | 1.50 |
| 409.41 | 4.30 | 4.30 |
| 220.27 | 4.21 | 4.21 |
| 307.31 | 1.53 | 1.53 |
| 278.36 | 4.17 | 4.17 |
| 365.35 | 0.88 | 0.88 |
| 414.45 | 3.52 | 3.52 |
| 307.42 | 4.68 | 4.68 |
| 328.42 | 5.06 | 5.06 |
| 391.50 | 3.86 | 3.86 |
| 310.31 | 2.41 | 2.41 |
| 352.43 | 4.94 | 4.94 |
| 323.42 | 4.66 | 4.66 |
| 338.42 | 2.37 | 2.37 |
| 235.31 | 1.90 | 1.90 |
| 298.34 | 3.90 | 3.90 |
| 300.39 | 2.52 | 2.52 |
| 413.52 | 4.90 | 4.90 |
| 386.79 | 3.99 | 3.99 |
| 379.49 | 3.96 | 3.96 |
| 460.52 | 4.18 | 4.18 |
| 301.34 | 2.75 | 2.75 |
| 302.41 | 2.51 | 2.51 |
| 196.25 | 3.34 | 3.34 |
| 325.36 | 2.65 | 2.65 |
| 380.81 | 3.73 | 3.73 |
| 358.35 | 1.50 | 1.50 |
| 231.29 | 1.63 | 1.63 |
| 194.30 | 2.57 | 2.57 |
| 239.27 | 2.82 | 2.82 |
| 321.38 | 3.03 | 3.03 |
| 390.71 | 4.58 | 4.58 |
| 405.50 | 3.45 | 3.45 |
| 310.27 | 1.77 | 1.77 |
| 315.37 | 2.21 | 2.21 |
| 268.29 | 3.69 | 3.69 |
| 391.57 | 5.27 | 5.27 |
| 366.45 | 2.30 | 2.30 |
| 282.33 | 2.90 | 2.90 |
| 366.46 | 2.94 | 2.94 |
| 222.25 | 2.91 | 2.91 |
| 334.64 | 2.35 | 2.35 |
| 316.40 | 4.03 | 4.03 |
| 432.48 | 5.11 | 5.11 |
| 316.31 | 3.87 | 3.87 |
| 329.38 | 2.51 | 2.51 |
| 304.80 | 4.69 | 4.69 |
| 445.79 | 2.78 | 2.78 |
| 375.40 | 3.07 | 3.07 |
| 259.26 | 2.42 | 2.42 |
| 298.34 | 3.90 | 3.90 |
| 346.70 | 3.75 | 3.75 |
| 395.77 | 1.96 | 1.96 |
| 321.38 | 2.76 | 2.76 |
| 297.27 | 2.16 | 2.16 |
| 180.24 | 1.03 | 1.03 |
| 291.35 | 0.71 | 0.71 |
| 292.39 | 2.48 | 2.48 |
| 278.38 | 3.34 | 3.34 |
| 264.33 | 3.86 | 3.86 |
| 377.42 | 2.97 | 2.97 |
| 310.31 | 3.55 | 3.55 |
| 331.71 | 3.61 | 3.61 |
| 305.21 | 2.55 | 2.55 |
| 432.91 | 3.84 | 3.84 |
| 264.33 | 3.86 | 3.86 |
| 384.55 | 4.17 | 4.17 |
| 298.35 | 1.66 | 1.66 |
| 298.35 | 3.80 | 3.80 |
| 330.34 | 4.17 | 4.17 |
| 361.27 | 2.69 | 2.69 |
| 314.33 | 2.31 | 2.31 |
| 259.31 | 2.21 | 2.21 |
| 260.28 | 0.35 | 0.35 |
| 219.67 | 3.32 | 3.32 |
| 329.36 | 1.15 | 1.15 |
| 312.40 | 3.33 | 3.33 |
| 490.54 | 2.06 | 2.06 |
| 253.35 | 3.24 | 3.24 |
| 277.28 | 2.99 | 2.99 |
| 383.52 | 4.54 | 4.54 |
| 313.37 | 0.47 | 0.47 |
| 398.46 | 3.18 | 3.18 |
| 264.33 | 3.86 | 3.86 |
| 368.44 | 3.17 | 3.17 |
| 349.82 | 2.87 | 2.87 |
| 309.39 | 4.27 | 4.27 |
| 314.39 | 2.72 | 2.72 |
| 205.26 | 2.70 | 2.70 |
| 296.41 | 4.30 | 4.30 |
| 467.25 | 4.85 | 4.85 |
| 326.38 | 2.67 | 2.67 |
| 392.46 | 3.20 | 3.20 |
| 355.19 | 3.87 | 3.87 |
| 322.41 | 4.93 | 4.93 |
| 192.17 | 1.51 | 1.51 |
| 260.39 | 3.83 | 3.83 |
| 177.16 | 1.35 | 1.35 |
| 349.43 | 4.91 | 4.91 |
| 410.38 | 3.71 | 3.71 |
| 238.34 | 2.43 | 2.43 |
| 398.40 | 2.15 | 2.15 |
| 294.31 | 2.91 | 2.91 |
| 223.28 | 2.97 | 2.97 |
| 258.30 | 1.27 | 1.27 |
| 275.37 | 3.87 | 3.87 |
| 477.63 | 4.54 | 4.54 |
| 330.78 | 2.37 | 2.37 |
| 480.62 | 4.42 | 4.42 |
| 293.40 | 4.57 | 4.57 |
| 346.39 | ||
| 385.49 | 3.70 | 3.70 |
| 267.38 | 3.54 | 3.54 |
| 293.33 | 2.25 | 2.25 |
| 241.34 | 3.46 | 3.46 |
| 424.48 | 1.68 | 1.68 |
| 263.21 | 2.56 | 2.56 |
| 148.17 | 0.73 | 0.73 |
| 351.45 | 2.35 | 2.35 |
| 383.88 | 5.64 | 5.64 |
| 261.35 | 2.90 | 2.90 |
| 330.14 | 4.26 | 4.26 |
| 360.89 | 4.96 | 4.96 |
| 259.33 | 2.84 | 2.84 |
| 226.32 | 3.46 | 3.46 |
| 345.47 | 2.82 | 2.82 |
| 346.39 | 2.24 | 2.24 |
| 285.17 | 1.63 | 1.63 |
| 362.30 | 3.44 | 3.44 |
| 327.30 | 2.48 | 2.48 |
| 334.36 | 1.25 | 1.25 |
| 366.42 | 2.53 | 2.53 |
| 317.43 | 4.70 | 4.70 |
| 197.24 | 2.82 | 2.82 |
| 354.84 | 3.31 | 3.31 |
| 532.46 | 5.36 | 5.36 |
| 373.37 | 2.55 | 2.55 |
| 530.74 | 4.65 | 4.65 |
| 272.35 | 3.28 | 3.28 |
| 381.44 | 0.93 | 0.93 |
| 309.39 | 4.27 | 4.27 |
| 290.11 | 0.17 | 0.17 |
| 314.34 | 3.24 | 3.24 |
| 307.63 | 3.85 | 3.85 |
| 241.29 | 3.47 | 3.47 |
| 348.00 | 2.97 | 2.97 |
| 263.17 | 3.74 | 3.74 |
| 253.74 | 2.96 | 2.96 |
| 323.23 | 3.76 | 3.76 |
| 368.44 | 2.53 | 2.53 |
| 284.37 | 2.05 | 2.05 |
| 384.44 | 1.30 | 1.30 |
| 327.30 | 1.91 | 1.91 |
| 395.40 | 3.44 | 3.44 |
| 332.36 | 3.67 | 3.67 |
| 257.77 | 3.10 | 3.10 |
| 307.78 | 5.05 | 5.05 |
| 316.36 | 4.00 | 4.00 |
| 338.37 | 2.44 | 2.44 |
| 305.36 | 2.53 | 2.53 |
| 279.34 | 4.31 | 4.31 |
| 391.47 | 2.82 | 2.82 |
| 366.44 | 4.38 | 4.38 |
| 415.47 | 3.38 | 3.38 |
| 227.26 | 3.16 | 3.16 |
| 429.48 | 4.11 | 4.11 |
| 375.41 | 2.36 | 2.36 |
| 300.79 | 3.27 | 3.27 |
| 336.42 | 4.37 | 4.37 |
| 291.33 | 2.22 | 2.22 |
| 305.36 | 4.30 | 4.30 |
| 375.48 | 3.59 | 3.59 |
| 238.24 | 0.47 | 0.47 |
| 282.32 | 4.56 | 4.56 |
| 293.32 | 4.03 | 4.03 |
| 341.36 | 3.19 | 3.19 |
| 368.44 | 1.60 | 1.60 |
| 331.17 | 4.35 | 4.35 |
| 329.40 | 4.50 | 4.50 |
| 438.42 | 1.18 | 1.18 |
| 382.47 | 1.90 | 1.90 |
| 359.38 | 2.89 | 2.89 |
| 216.28 | 2.46 | 2.46 |
| 400.44 | 1.01 | 1.01 |
| 319.38 | 2.86 | 2.86 |
| 314.34 | 5.53 | 5.53 |
| 318.81 | 2.71 | 2.71 |
| 253.34 | 4.30 | 4.30 |
| 350.33 | 3.32 | 3.32 |
| 275.30 | 0.68 | 0.68 |
| 322.41 | 1.56 | 1.56 |
| 382.42 | 1.34 | 1.34 |
| 332.41 | 3.46 | 3.46 |
| 425.30 | 3.43 | 3.43 |
| 354.37 | 2.25 | 2.25 |
| 479.61 | 4.40 | 4.40 |
| 382.22 | 4.64 | 4.64 |
| 423.89 | 3.45 | 3.45 |
| 386.48 | 5.53 | 5.53 |
| 388.36 | 2.25 | 2.25 |
| 279.32 | 1.39 | 1.39 |
| 449.49 | 0.91 | 0.91 |
| 366.44 | 4.38 | 4.38 |
| 407.45 | 1.60 | 1.60 |
| 264.28 | 3.40 | 3.40 |
| 334.38 | 3.84 | 3.84 |
| 314.39 | 2.06 | 2.06 |
| 384.44 | 1.47 | 1.47 |
| 294.31 | 4.21 | 4.21 |
| 324.41 | 0.23 | 0.23 |
| 282.30 | 2.98 | 2.98 |
| 343.39 | 3.36 | 3.36 |
| 264.71 | 3.37 | 3.37 |
| 399.24 | 4.00 | 4.00 |
| 313.28 | 1.61 | 1.61 |
| 293.35 | 1.78 | 1.78 |
| 270.24 | 3.07 | 3.07 |
| 288.33 | 1.81 | 1.81 |
| 387.26 | 3.64 | 3.64 |
| 295.43 | 1.99 | 1.99 |
| 344.33 | 1.79 | 1.79 |
| 381.43 | 4.37 | 4.37 |
| 301.35 | 4.18 | 4.18 |
| 317.39 | 3.79 | 3.79 |
| 378.41 | 0.79 | 0.79 |
| 365.39 | 2.97 | 2.97 |
| 462.42 | 2.63 | 2.63 |
| 331.32 | 2.31 | 2.31 |
| 338.37 | 2.54 | 2.54 |
| 369.37 | 3.67 | 3.67 |
| 368.40 | 3.07 | 3.07 |
| 277.30 | 1.83 | 1.83 |
| 286.36 | 3.70 | 3.70 |
| 339.42 | 4.84 | 4.84 |
| 323.35 | 4.04 | 4.04 |
| 333.39 | 4.05 | 4.05 |
| 308.34 | 4.52 | 4.52 |
| 231.32 | 3.82 | 3.82 |
| 347.37 | 3.10 | 3.10 |
| 336.42 | 4.37 | 4.37 |
| 447.54 | 4.18 | 4.18 |
| 319.36 | 3.66 | 3.66 |
| 319.31 | 0.67 | 0.67 |
| 439.47 | 4.61 | 4.61 |
| 251.29 | 3.33 | 3.33 |
| 276.34 | 4.38 | 4.38 |