Basic Information
ID: ALA1614549
Type: Binding
Description: PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3). (Class of assay: confirmatory) [Related pubchem assays: 746 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1614549
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 212.28 | 3.36 | 3.36 |
| 194.24 | 3.23 | 3.23 |
| 224.26 | 3.03 | 3.03 |
| 332.41 | 3.07 | 3.07 |
| 209.25 | 2.66 | 2.66 |
| 422.44 | 5.33 | 5.33 |
| 327.44 | 4.27 | 4.27 |
| 236.27 | 3.31 | 3.31 |
| 223.23 | 2.70 | 2.70 |
| 481.51 | 2.36 | 2.36 |
| 458.49 | 2.84 | 2.84 |
| 302.37 | 2.64 | 2.64 |
| 285.30 | 2.19 | 2.19 |
| 321.34 | 2.96 | 2.96 |
| 356.38 | 2.13 | 2.13 |
| 447.54 | 2.51 | 2.51 |
| 340.34 | 2.31 | 2.31 |
| 393.49 | 2.27 | 2.27 |
| 363.42 | 4.06 | 4.06 |
| 338.36 | 3.03 | 3.03 |
| 300.27 | 3.17 | 3.17 |
| 323.15 | 1.84 | 1.84 |
| 363.38 | 3.63 | 3.63 |
| 252.28 | 1.89 | 1.89 |
| 414.47 | 3.02 | 3.02 |
| 257.11 | 2.79 | 2.79 |
| 289.34 | 3.45 | 3.45 |
| 218.28 | 2.25 | 2.25 |
| 317.35 | 3.92 | 3.92 |
| 434.57 | 3.15 | 3.15 |
| 344.37 | 2.81 | 2.81 |
| 351.16 | 3.78 | 3.78 |
| 334.40 | 3.53 | 3.53 |
| 416.48 | 3.16 | 3.16 |
| 269.28 | 1.36 | 1.36 |
| 293.32 | 3.61 | 3.61 |
| 323.35 | 3.12 | 3.12 |
| 231.30 | 2.25 | 2.25 |
| 469.52 | 2.75 | 2.75 |
| 263.30 | 3.10 | 3.10 |
| 308.36 | 2.35 | 2.35 |
| 223.23 | 2.24 | 2.24 |
| 423.54 | 3.62 | 3.62 |
| 298.29 | 3.48 | 3.48 |
| 219.22 | 1.52 | 1.52 |
| 365.48 | 3.01 | 3.01 |
| 337.16 | 3.47 | 3.47 |
| 285.30 | 2.49 | 2.49 |
| 306.41 | 2.58 | 2.58 |
| 343.41 | 2.75 | 2.75 |
| 251.13 | 2.98 | 2.98 |
| 427.49 | 2.83 | 2.83 |
| 368.39 | 2.77 | 2.77 |
| 386.40 | 2.85 | 2.85 |
| 353.38 | 2.12 | 2.12 |
| 303.41 | 2.95 | 2.95 |
| 314.37 | 2.94 | 2.94 |
| 233.29 | 2.80 | 2.80 |
| 326.38 | 3.28 | 3.28 |
| 366.17 | 2.14 | 2.14 |
| 252.34 | 2.37 | 2.37 |
| 292.30 | 2.29 | 2.29 |
| 367.50 | 2.93 | 2.93 |
| 409.44 | 2.83 | 2.83 |
| 291.30 | 2.17 | 2.17 |
| 349.44 | 3.82 | 3.82 |
| 418.50 | 1.67 | 1.67 |
| 297.31 | 2.22 | 2.22 |
| 332.39 | 4.54 | 4.54 |
| 242.23 | 1.33 | 1.33 |
| 204.22 | 2.37 | 2.37 |
| 356.38 | 2.13 | 2.13 |
| 405.48 | 2.11 | 2.11 |
| 321.41 | 3.80 | 3.80 |
| 335.20 | 3.89 | 3.89 |
| 462.62 | 4.21 | 4.21 |
| 300.29 | 3.07 | 3.07 |
| 261.28 | 3.26 | 3.26 |
| 342.42 | 3.61 | 3.61 |
| 319.84 | 2.34 | 2.34 |
| 362.46 | 4.03 | 4.03 |
| 219.24 | 2.36 | 2.36 |
| 317.37 | 2.38 | 2.38 |
| 416.43 | 2.86 | 2.86 |
| 333.82 | 2.82 | 2.82 |
| 456.53 | 2.10 | 2.10 |
| 262.32 | 3.96 | 3.96 |
| 236.25 | 1.69 | 1.69 |
| 237.26 | 2.33 | 2.33 |
| 347.40 | 2.35 | 2.35 |
| 451.28 | 4.02 | 4.02 |
| 279.35 | 3.33 | 3.33 |
| 291.31 | 3.02 | 3.02 |
| 263.26 | 3.46 | 3.46 |
| 340.41 | 2.90 | 2.90 |
| 360.37 | 2.52 | 2.52 |
| 265.31 | 3.12 | 3.12 |
| 331.17 | 2.60 | 2.60 |
| 242.69 | 2.69 | 2.69 |
| 449.51 | 4.24 | 4.24 |
| 373.46 | 3.22 | 3.22 |
| 366.37 | 2.74 | 2.74 |
| 349.43 | 3.30 | 3.30 |
| 434.49 | 4.10 | 4.10 |
| 297.36 | 3.32 | 3.32 |
| 344.37 | 3.74 | 3.74 |
| 251.29 | 2.73 | 2.73 |
| 309.30 | 2.83 | 2.83 |
| 219.25 | 3.22 | 3.22 |
| 359.41 | 3.59 | 3.59 |
| 416.47 | 3.08 | 3.08 |
| 219.26 | 2.41 | 2.41 |
| 304.37 | 2.30 | 2.30 |
| 351.20 | 3.13 | 3.13 |
| 396.43 | 2.74 | 2.74 |
| 421.48 | 0.78 | 0.78 |
| 317.43 | 2.37 | 2.37 |
| 440.53 | 2.60 | 2.60 |
| 275.31 | 1.08 | 1.08 |
| 447.58 | 2.99 | 2.99 |
| 277.75 | 3.94 | 3.94 |
| 371.39 | 1.46 | 1.46 |
| 301.35 | 3.43 | 3.43 |
| 366.40 | 2.10 | 2.10 |
| 296.33 | 3.39 | 3.39 |
| 190.20 | 1.74 | 1.74 |
| 348.36 | 3.59 | 3.59 |
| 474.95 | 3.35 | 3.35 |
| 239.28 | 1.98 | 1.98 |
| 255.30 | 3.38 | 3.38 |
| 281.36 | 3.16 | 3.16 |
| 348.38 | 2.10 | 2.10 |
| 303.37 | 3.66 | 3.66 |
| 241.70 | 2.66 | 2.66 |
| 285.34 | 2.70 | 2.70 |
| 268.27 | 2.81 | 2.81 |
| 382.42 | 3.51 | 3.51 |
| 382.42 | 3.16 | 3.16 |
| 365.23 | 4.42 | 4.42 |
| 333.37 | 1.16 | 1.16 |
| 364.24 | 3.05 | 3.05 |
| 339.42 | 2.97 | 2.97 |
| 412.72 | 4.09 | 4.09 |
| 351.41 | 3.04 | 3.04 |
| 314.37 | 1.92 | 1.92 |
| 417.46 | 2.97 | 2.97 |
| 317.35 | 1.45 | 1.45 |
| 243.70 | 3.31 | 3.31 |
| 462.58 | 4.55 | 4.55 |
| 307.35 | 3.50 | 3.50 |
| 274.28 | 1.03 | 1.03 |
| 391.29 | 2.02 | 2.02 |
| 291.33 | 2.80 | 2.80 |
| 280.35 | 1.45 | 1.45 |
| 358.44 | 3.68 | 3.68 |
| 368.39 | 3.04 | 3.04 |
| 452.47 | 3.40 | 3.40 |
| 409.49 | 2.61 | 2.61 |
| 300.31 | 1.81 | 1.81 |
| 444.52 | 3.29 | 3.29 |
| 302.33 | 3.46 | 3.46 |
| 203.29 | 1.92 | 1.92 |
| 280.28 | 2.81 | 2.81 |
| 386.82 | 3.70 | 3.70 |
| 293.24 | 1.03 | 1.03 |
| 446.55 | 2.85 | 2.85 |
| 265.31 | 3.12 | 3.12 |
| 255.26 | 2.55 | 2.55 |
| 320.35 | 2.94 | 2.94 |
| 271.32 | 3.25 | 3.25 |
| 235.25 | 2.30 | 2.30 |
| 373.21 | 4.27 | 4.27 |
| 387.51 | 2.72 | 2.72 |
| 438.48 | 2.78 | 2.78 |
| 323.15 | 1.84 | 1.84 |
| 269.33 | 2.50 | 2.50 |
| 260.25 | 0.69 | 0.69 |
| 319.34 | 2.31 | 2.31 |
| 210.26 | 1.20 | 1.20 |
| 489.60 | 4.84 | 4.84 |
| 299.33 | 2.88 | 2.88 |
| 360.37 | 3.67 | 3.67 |
| 261.28 | 1.84 | 1.84 |
| 427.35 | 3.98 | 3.98 |
| 253.26 | 3.27 | 3.27 |
| 417.53 | 2.98 | 2.98 |
| 227.27 | 2.54 | 2.54 |
| 314.37 | 3.08 | 3.08 |
| 334.38 | 2.90 | 2.90 |
| 367.41 | 2.51 | 2.51 |
| 256.31 | 2.58 | 2.58 |
| 342.33 | 2.74 | 2.74 |
| 305.33 | 1.08 | 1.08 |
| 356.38 | 2.84 | 2.84 |
| 291.38 | 2.79 | 2.79 |
| 382.21 | 2.46 | 2.46 |
| 392.71 | 3.01 | 3.01 |
| 339.36 | 2.08 | 2.08 |
| 346.44 | 3.03 | 3.03 |
| 324.34 | 2.23 | 2.23 |
| 266.30 | 3.07 | 3.07 |
| 440.50 | 2.70 | 2.70 |
| 441.49 | 2.10 | 2.10 |
| 309.34 | 2.14 | 2.14 |
| 331.44 | 2.90 | 2.90 |
| 310.31 | 2.79 | 2.79 |
| 249.31 | 2.32 | 2.32 |
| 289.27 | 2.25 | 2.25 |
| 298.29 | 3.39 | 3.39 |
| 367.41 | 1.50 | 1.50 |
| 308.34 | 2.62 | 2.62 |
| 237.24 | 3.36 | 3.36 |
| 283.29 | 0.52 | 0.52 |
| 414.85 | 2.48 | 2.48 |
| 219.22 | 1.52 | 1.52 |
| 356.39 | 2.71 | 2.71 |
| 327.34 | 3.75 | 3.75 |
| 286.36 | 3.04 | 3.04 |
| 439.99 | 3.15 | 3.15 |
| 276.32 | 1.86 | 1.86 |
| 309.32 | 2.54 | 2.54 |
| 262.29 | 2.32 | 2.32 |
| 292.36 | 2.65 | 2.65 |
| 458.52 | 2.72 | 2.72 |
| 362.41 | 2.49 | 2.49 |
| 350.42 | 2.75 | 2.75 |
| 410.45 | 0.55 | 0.55 |
| 332.41 | 2.21 | 2.21 |
| 341.37 | 2.29 | 2.29 |
| 401.46 | 1.66 | 1.66 |
| 338.36 | 3.03 | 3.03 |
| 331.37 | 4.28 | 4.28 |
| 409.48 | 2.80 | 2.80 |
| 314.21 | 2.79 | 2.79 |
| 426.50 | 2.21 | 2.21 |
| 315.15 | 1.84 | 1.84 |
| 253.30 | 3.06 | 3.06 |
| 318.38 | 3.72 | 3.72 |
| 428.47 | 2.14 | 2.14 |
| 303.27 | 1.86 | 1.86 |
| 330.16 | 3.14 | 3.14 |
| 326.33 | 3.16 | 3.16 |
| 251.26 | 2.38 | 2.38 |
| 385.65 | 4.69 | 4.69 |
| 377.44 | 2.43 | 2.43 |
| 288.33 | 2.57 | 2.57 |
| 309.41 | 3.39 | 3.39 |
| 315.44 | 3.30 | 3.30 |
| 264.33 | 2.72 | 2.72 |
| 315.38 | 3.57 | 3.57 |
| 368.39 | 3.04 | 3.04 |
| 331.40 | 2.65 | 2.65 |
| 192.24 | 2.33 | 2.33 |
| 458.58 | 3.17 | 3.17 |
| 377.24 | 3.19 | 3.19 |
| 305.33 | 1.90 | 1.90 |
| 462.30 | 4.90 | 4.90 |
| 321.76 | 2.86 | 2.86 |
| 376.36 | 2.92 | 2.92 |
| 351.23 | 3.34 | 3.34 |
| 308.38 | 2.98 | 2.98 |
| 383.43 | 2.85 | 2.85 |
| 184.24 | 2.57 | 2.57 |
| 193.25 | 0.80 | 0.80 |
| 248.31 | 2.51 | 2.51 |
| 330.37 | 2.99 | 2.99 |
| 257.32 | 2.55 | 2.55 |
| 303.31 | 2.86 | 2.86 |
| 282.37 | 3.41 | 3.41 |
| 300.27 | 1.65 | 1.65 |
| 409.49 | 2.61 | 2.61 |
| 302.36 | 2.60 | 2.60 |
| 233.29 | 2.80 | 2.80 |
| 485.54 | 2.33 | 2.33 |
| 298.27 | 2.92 | 2.92 |
| 324.34 | 3.18 | 3.18 |
| 295.30 | 1.63 | 1.63 |
| 224.31 | 3.89 | 3.89 |
| 293.37 | 3.64 | 3.64 |
| 368.39 | 1.95 | 1.95 |
| 295.37 | 3.89 | 3.89 |
| 384.31 | 3.92 | 3.92 |
| 477.56 | 2.52 | 2.52 |
| 398.42 | 2.78 | 2.78 |
| 404.45 | 2.14 | 2.14 |
| 308.37 | 3.36 | 3.36 |
| 449.51 | 4.24 | 4.24 |
| 329.40 | 2.73 | 2.73 |
| 208.24 | 2.03 | 2.03 |
| 252.32 | 2.16 | 2.16 |
| 377.44 | 2.43 | 2.43 |
| 302.33 | 4.63 | 4.63 |
| 231.25 | 1.20 | 1.20 |
| 270.24 | 2.38 | 2.38 |
| 287.41 | 3.13 | 3.13 |
| 447.54 | 4.20 | 4.20 |
| 276.30 | 2.65 | 2.65 |
| 248.31 | 2.98 | 2.98 |
| 355.45 | 3.53 | 3.53 |
| 316.32 | 4.24 | 4.24 |
| 238.29 | 3.31 | 3.31 |
| 457.55 | 3.52 | 3.52 |
| 321.36 | 4.20 | 4.20 |
| 263.16 | 3.03 | 3.03 |
| 266.37 | 2.46 | 2.46 |
| 403.44 | 2.19 | 2.19 |
| 468.56 | 3.32 | 3.32 |
| 418.50 | 3.87 | 3.87 |
| 281.31 | 3.72 | 3.72 |
| 223.28 | 2.97 | 2.97 |
| 353.41 | 2.54 | 2.54 |
| 322.39 | 2.66 | 2.66 |
| 366.17 | 2.17 | 2.17 |
| 386.40 | 2.85 | 2.85 |
| 262.29 | 2.18 | 2.18 |
| 310.74 | 3.34 | 3.34 |
| 293.16 | 2.91 | 2.91 |
| 360.37 | 1.74 | 1.74 |
| 298.32 | 3.27 | 3.27 |
| 326.31 | 0.85 | 0.85 |
| 340.34 | 1.75 | 1.75 |
| 352.39 | 2.71 | 2.71 |
| 495.60 | 2.72 | 2.72 |
| 439.46 | 4.09 | 4.09 |
| 375.49 | 2.63 | 2.63 |
| 350.40 | 2.05 | 2.05 |
| 311.34 | 2.51 | 2.51 |
| 373.48 | 1.95 | 1.95 |
| 366.46 | 2.53 | 2.53 |
| 244.32 | 2.38 | 2.38 |
| 434.45 | 4.17 | 4.17 |
| 336.85 | 3.56 | 3.56 |
| 280.37 | 2.78 | 2.78 |
| 260.32 | 2.36 | 2.36 |
| 235.25 | 2.74 | 2.74 |
| 215.26 | 1.70 | 1.70 |
| 374.44 | 3.15 | 3.15 |
| 336.18 | 3.52 | 3.52 |
| 273.11 | 2.75 | 2.75 |
| 365.82 | 1.42 | 1.42 |
| 341.44 | 3.18 | 3.18 |
| 228.28 | 2.80 | 2.80 |
| 269.37 | 3.08 | 3.08 |
| 262.33 | 2.32 | 2.32 |
| 267.28 | 3.41 | 3.41 |
| 267.28 | 3.07 | 3.07 |
| 253.26 | 2.68 | 2.68 |
| 278.31 | 3.21 | 3.21 |
| 374.49 | 3.67 | 3.67 |
| 280.28 | 3.35 | 3.35 |
| 296.33 | 3.64 | 3.64 |
| 243.29 | 3.08 | 3.08 |
| 268.32 | 1.94 | 1.94 |
| 352.42 | 4.10 | 4.10 |
| 264.28 | 2.82 | 2.82 |
| 251.29 | 3.33 | 3.33 |
| 212.21 | 2.62 | 2.62 |
| 296.33 | 2.52 | 2.52 |
| 295.34 | 2.90 | 2.90 |
| 294.31 | 3.40 | 3.40 |
| 265.27 | 3.26 | 3.26 |
| 306.37 | 3.52 | 3.52 |