Basic Information
ID: ALA1638622
Type: Binding
Description: Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoazetidin-2-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid from human NCP1L1 expressed in HEK 293
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1638622
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.69 | 4.28 | 4.28 |
| 546.71 | 3.64 | 3.64 |
| 520.63 | 2.55 | 2.55 |
| 534.66 | 2.94 | 2.94 |
| 548.68 | 3.33 | 3.33 |
| 562.71 | 3.72 | 3.72 |
| 576.74 | 4.11 | 4.11 |
| 506.60 | 2.47 | 2.47 |
| 520.63 | 2.86 | 2.86 |
| 631.82 | 4.78 | 4.78 |
| 534.66 | 3.25 | 3.25 |
| 657.86 | 5.53 | 5.53 |
| 548.68 | 3.64 | 3.64 |
| 562.71 | 4.03 | 4.03 |
| 657.86 | 5.53 | 5.53 |
| 478.59 | 2.33 | 2.33 |
| 492.62 | 2.37 | 2.37 |
| 506.65 | 2.76 | 2.76 |
| 520.67 | 3.15 | 3.15 |
| 534.70 | 3.54 | 3.54 |
| 577.73 | 3.86 | 3.86 |
| 591.75 | 3.91 | 3.91 |
| 605.78 | 4.30 | 4.30 |
| 726.97 | 7.23 | 7.23 |
| 666.91 | 6.01 | 6.01 |
| 692.95 | 6.76 | 6.76 |
| 652.88 | 5.76 | 5.76 |
| 678.92 | 6.51 | 6.51 |
| 588.79 | 5.12 | 5.12 |
| 614.83 | 5.87 | 5.87 |
| 700.93 | 6.48 | 6.48 |
| 652.88 | 5.76 | 5.76 |
| 678.92 | 6.51 | 6.51 |
| 555.70 | 1.89 | 1.89 |
| 569.73 | 1.93 | 1.93 |
| 619.81 | 4.69 | 4.69 |
| 633.83 | 5.08 | 5.08 |
| 631.82 | 4.78 | 4.78 |
| 477.61 | 2.30 | 2.30 |
| 491.64 | 2.34 | 2.34 |
| 505.66 | 2.73 | 2.73 |
| 519.69 | 3.12 | 3.12 |
| 533.72 | 3.51 | 3.51 |
| 583.76 | 2.32 | 2.32 |
| 597.78 | 2.71 | 2.71 |
| 611.81 | 3.10 | 3.10 |
| 546.67 | 3.30 | 3.30 |
| 560.70 | 3.69 | 3.69 |
| 574.72 | 4.08 | 4.08 |
| 588.75 | 4.47 | 4.47 |
| 602.78 | 4.87 | 4.87 |
| 617.79 | 4.66 | 4.66 |
| 603.76 | 4.61 | 4.61 |
| 560.74 | 4.29 | 4.29 |
| 546.71 | 3.90 | 3.90 |
| 532.69 | 3.51 | 3.51 |
| 504.63 | 3.08 | 3.08 |
| 518.66 | 3.12 | 3.12 |
| 631.82 | 5.05 | 5.05 |
| 645.84 | 5.44 | 5.44 |
| 659.87 | 5.83 | 5.83 |
| 503.65 | 3.05 | 3.05 |
| 517.67 | 3.09 | 3.09 |
| 531.70 | 3.48 | 3.48 |
| 545.73 | 3.87 | 3.87 |
| 559.76 | 4.26 | 4.26 |
| 581.74 | 2.64 | 2.64 |
| 595.77 | 2.68 | 2.68 |
| 609.79 | 3.07 | 3.07 |
| 623.82 | 3.46 | 3.46 |
| 637.85 | 3.85 | 3.85 |
| 617.79 | 4.34 | 4.34 |
| 643.83 | 5.09 | 5.09 |
| 517.67 | 2.70 | 2.70 |
| 543.71 | 3.45 | 3.45 |
| 595.77 | 2.37 | 2.37 |
| 621.80 | 3.12 | 3.12 |
| 657.84 | 3.80 | 3.80 |
| 683.88 | 4.55 | 4.55 |
| 570.78 | 5.66 | 5.66 |
| 544.74 | 4.91 | 4.91 |
| 530.71 | 4.52 | 4.52 |
| 621.78 | 4.25 | 4.25 |
| 556.75 | 5.27 | 5.27 |
| 586.78 | 4.64 | 4.64 |
| 647.82 | 5.00 | 5.00 |
| 542.72 | 5.03 | 5.03 |
| 546.71 | 3.50 | 3.50 |
| 572.75 | 4.25 | 4.25 |
| 560.74 | 3.89 | 3.89 |
| 572.75 | 4.39 | 4.39 |
| 560.74 | 4.03 | 4.03 |
| 586.78 | 4.78 | 4.78 |
| 546.71 | 3.50 | 3.50 |
| 572.75 | 4.25 | 4.25 |
| 532.69 | 3.25 | 3.25 |
| 558.72 | 4.00 | 4.00 |
| 532.69 | 3.25 | 3.25 |
| 558.72 | 4.00 | 4.00 |
| 645.85 | 5.03 | 5.03 |
| 671.88 | 5.78 | 5.78 |
| 645.85 | 5.03 | 5.03 |
| 671.88 | 5.78 | 5.78 |
| 588.75 | 4.07 | 4.07 |
| 614.79 | 4.82 | 4.82 |
| 588.75 | 4.07 | 4.07 |
| 614.79 | 4.82 | 4.82 |
| 615.82 | 4.37 | 4.37 |
| 641.86 | 5.12 | 5.12 |
| 559.71 | 2.99 | 2.99 |
| 585.75 | 3.74 | 3.74 |