Basic Information
ID: ALA1645700
Type: Functional
Description: Antiproliferative activity against growth-resistant human PC9 cells expressing EGFR E746_A750/T790M mutant
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PC-9
Target: PC-9(ALA614102)
Document: ALA1641501
Antiproliferative activity against growth-resistant human PC9 cells expressing EGFR E746_A750/T790M mutant: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1645700
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 494.98 | 4.55 | 4.55 |
| 448.53 | 3.06 | 3.06 |
| 461.57 | 2.44 | 2.44 |
| 489.58 | 2.07 | 2.07 |
| 462.56 | 3.08 | 3.08 |
| 470.54 | 3.77 | 3.77 |
| 357.37 | 3.94 | 3.94 |
| 407.43 | 5.04 | 5.04 |
| 386.41 | 4.55 | 4.55 |
| 357.37 | 3.94 | 3.94 |
| 407.43 | 5.09 | 5.09 |
| 414.82 | 4.94 | 4.94 |
| 473.92 | 5.86 | 5.86 |
| 481.94 | 4.64 | 4.64 |
| 495.97 | 4.76 | 4.76 |
| 494.00 | 5.61 | 5.61 |
| 494.00 | 5.61 | 5.61 |
| 491.98 | 5.52 | 5.52 |
| 464.96 | 4.54 | 4.54 |
| 578.12 | 5.02 | 5.02 |
| 492.97 | 4.18 | 4.18 |
| 522.99 | 4.19 | 4.19 |
| 553.02 | 3.86 | 3.86 |
| 506.99 | 4.61 | 4.61 |
| 537.02 | 4.62 | 4.62 |
| 478.98 | 4.54 | 4.54 |
| 546.98 | 5.56 | 5.56 |
| 506.99 | 4.11 | 4.11 |
| 493.01 | 4.58 | 4.58 |
| 532.95 | 5.56 | 5.56 |
| 511.05 | 4.91 | 4.91 |
| 481.03 | 4.90 | 4.90 |
| 494.00 | 4.50 | 4.50 |
| 529.43 | 5.20 | 5.20 |
| 512.97 | 4.69 | 4.69 |
| 512.97 | 4.69 | 4.69 |
| 430.51 | 3.89 | 3.89 |
| 498.51 | 4.91 | 4.91 |
| 509.41 | 4.65 | 4.65 |