Basic Information
ID: ALA1648235
Type: Functional
Description: Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Glucagon receptor(ALA1985)
Document: ALA1641377
Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1648235
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 563.62 | 6.43 | 6.43 |
| 559.59 | 5.99 | 5.99 |
| 444.45 | 6.24 | 6.24 |
| 515.53 | 5.75 | 5.75 |
| 511.51 | 5.31 | 5.31 |
| 511.51 | 5.31 | 5.31 |
| 515.53 | 5.75 | 5.75 |
| 511.51 | 5.31 | 5.31 |
| 515.53 | 5.75 | 5.75 |
| 511.51 | 5.31 | 5.31 |
| 515.53 | 5.61 | 5.61 |
| 511.51 | 5.17 | 5.17 |
| 515.53 | 5.61 | 5.61 |
| 511.51 | 5.17 | 5.17 |
| 571.64 | 7.02 | 7.02 |
| 567.62 | 6.58 | 6.58 |
| 593.48 | 6.27 | 6.27 |
| 589.46 | 5.83 | 5.83 |
| 578.37 | 6.68 | 6.68 |
| 574.35 | 6.24 | 6.24 |
| 578.37 | 6.68 | 6.68 |
| 574.35 | 6.24 | 6.24 |
| 594.37 | 5.65 | 5.65 |
| 588.38 | 5.91 | 5.91 |
| 607.51 | 6.83 | 6.83 |
| 603.48 | 6.39 | 6.39 |
| 579.45 | 5.88 | 5.88 |
| 607.51 | 6.66 | 6.66 |
| 607.51 | 6.61 | 6.61 |
| 587.58 | 4.77 | 4.77 |
| 583.55 | 4.33 | 4.33 |
| 587.58 | 4.77 | 4.77 |
| 583.55 | 4.33 | 4.33 |
| 571.98 | 6.51 | 6.51 |
| 567.96 | 6.07 | 6.07 |
| 648.08 | 8.17 | 8.17 |
| 644.06 | 7.73 | 7.73 |
| 593.48 | 6.27 | 6.27 |
| 589.46 | 5.83 | 5.83 |
| 579.45 | 5.88 | 5.88 |
| 607.51 | 6.66 | 6.66 |