Basic Information
ID: ALA1648242
Type: Functional
Description: Antidiabetic activity in transgenic mouse expressing human GCGR assessed as inhibition of glucagon-induced blood glucose excursion at 10 mg/kg, po administered 60 mins before glucagon challenge measured after 48 mins
Format: BAO_0000218
Organism: Mus musculus
Tissue: Blood
Target: Mus musculus(ALA375)
Document: ALA1641377
Antidiabetic activity in transgenic mouse expressing human GCGR assessed as inhibition of glucagon-induced blood glucose excursion at 10 mg/kg, po administered 60 mins before glucagon challenge measured after 48 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1648242
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 567.62 | 6.58 | 6.58 |
| 589.46 | 5.83 | 5.83 |
| 578.37 | 6.68 | 6.68 |
| 574.35 | 6.24 | 6.24 |
| 588.38 | 5.91 | 5.91 |