Basic Information
ID: ALA1657947
Type: ADME
Description: Drug accumulation in Saccharomyces cerevisiae ADCDR1 expressing Candida albicans CDR1 efflux pump reenergized with glucose at pH 6.0 assessed as intracellular accumulation after 60 mins by fluorescamine staining
Organism: Saccharomyces cerevisiae
Strain: ADCDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA1657947
Drug uptake
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 89.09 | -0.58 | -0.58 |
| 306.28 | 0.74 | 0.74 |
| 160.17 | -1.08 | -1.08 |
| 495.45 | -3.48 | -3.48 |
| 183.18 | 0.78 | 0.78 |
| 171.16 | -0.95 | -0.95 |
| 231.25 | -1.57 | -1.57 |
| 148.12 | -1.71 | -1.71 |
| 3036.35 | ||
| 173.13 | -1.76 | -1.76 |
| 129.16 | 0.20 | 0.20 |
| 402.42 | -0.32 | -0.32 |
| 318.37 | -1.63 | -1.63 |
| 431.53 | -1.10 | -1.10 |
| 544.69 | -0.57 | -0.57 |
| 296.34 | 1.31 | 1.31 |
| 445.58 | 1.26 | 1.26 |
| 315.33 | -1.47 | -1.47 |
| 428.49 | -0.94 | -0.94 |
| 148.16 | -1.28 | -1.28 |