Basic Information
ID: ALA1680809
Type: Functional
Description: Antagonist activity against rat P2X4 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current by two-electrode voltage-clamp electrophysiology
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1680809
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.47 | 3.96 | 3.96 |
| 681.40 | 3.52 | 3.52 |
| 840.12 | 3.85 | 3.85 |
| 840.12 | 3.85 | 3.85 |
| 473.44 | 2.99 | 2.99 |
| 461.39 | 2.94 | 2.94 |
| 450.84 | 3.69 | 3.69 |
| 460.44 | 3.43 | 3.43 |
| 446.42 | 3.04 | 3.04 |
| 446.42 | 3.04 | 3.04 |
| 444.44 | 3.65 | 3.65 |
| 444.44 | 3.65 | 3.65 |
| 430.42 | 3.34 | 3.34 |
| 430.42 | 3.34 | 3.34 |
| 430.42 | 3.34 | 3.34 |
| 416.39 | 3.03 | 3.03 |
| 466.45 | 4.19 | 4.19 |
| 431.41 | 2.62 | 2.62 |
| 431.41 | 2.62 | 2.62 |
| 460.40 | 2.73 | 2.73 |
| 518.44 | 2.28 | 2.28 |
| 432.39 | 2.74 | 2.74 |
| 432.39 | 2.74 | 2.74 |
| 533.45 | 1.86 | 1.86 |
| 533.45 | 1.86 | 1.86 |
| 475.41 | 2.31 | 2.31 |
| 494.84 | 3.39 | 3.39 |
| 494.84 | 3.39 | 3.39 |
| 473.49 | 3.54 | 3.54 |
| 623.37 | 3.97 | 3.97 |
| 579.36 | 4.27 | 4.27 |
| 676.98 | 2.87 | 2.87 |
| 609.55 | 4.02 | 4.02 |
| 611.53 | 2.81 | 2.81 |
| 509.48 | 3.57 | 3.57 |
| 328.37 | 4.10 | 4.10 |
| 422.44 | 3.04 | 3.04 |
| 508.49 | 4.83 | 4.83 |
| 434.38 | 3.17 | 3.17 |
| 431.41 | 2.62 | 2.62 |
| 460.40 | 2.73 | 2.73 |
| 460.40 | 2.73 | 2.73 |
| 518.44 | 2.28 | 2.28 |
| 474.43 | 2.66 | 2.66 |
| 566.50 | 4.80 | 4.80 |
| 342.40 | 4.40 | 4.40 |
| 484.39 | 4.05 | 4.05 |
| 444.44 | 3.60 | 3.60 |
| 444.44 | 3.65 | 3.65 |
| 446.42 | 3.04 | 3.04 |
| 476.44 | 3.05 | 3.05 |
| 434.38 | 3.17 | 3.17 |
| 495.29 | 3.80 | 3.80 |
| 452.37 | 3.31 | 3.31 |
| 506.52 | 4.63 | 4.63 |
| 508.49 | 4.83 | 4.83 |
| 476.40 | 2.44 | 2.44 |
| 445.43 | 2.93 | 2.93 |
| 681.40 | 3.52 | 3.52 |
| 579.36 | 4.27 | 4.27 |
| 542.47 | 2.37 | 2.37 |
| 644.51 | 1.62 | 1.62 |