Basic Information
ID: ALA1680964
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1680964
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 437.90 | 2.16 | 2.16 |
| 399.90 | 1.46 | 1.46 |
| 427.95 | 2.24 | 2.24 |
| 441.98 | 2.63 | 2.63 |
| 456.00 | 3.03 | 3.03 |
| 470.03 | 3.42 | 3.42 |
| 413.92 | 2.03 | 2.03 |
| 425.93 | 2.33 | 2.33 |
| 411.91 | 1.63 | 1.63 |
| 439.96 | 2.56 | 2.56 |
| 453.99 | 2.95 | 2.95 |
| 415.90 | 1.30 | 1.30 |
| 429.92 | 1.69 | 1.69 |
| 443.95 | 2.08 | 2.08 |
| 457.98 | 2.47 | 2.47 |
| 431.96 | 2.01 | 2.01 |
| 445.99 | 2.40 | 2.40 |
| 460.02 | 2.79 | 2.79 |
| 474.04 | 3.18 | 3.18 |
| 447.94 | 2.57 | 2.57 |
| 465.93 | 2.71 | 2.71 |
| 524.04 | 4.24 | 4.24 |
| 437.90 | 2.16 | 2.16 |
| 453.97 | 2.63 | 2.63 |
| 453.97 | 2.63 | 2.63 |
| 488.41 | 3.28 | 3.28 |
| 454.96 | 2.03 | 2.03 |
| 455.95 | 1.42 | 1.42 |
| 443.91 | 1.08 | 1.08 |
| 415.85 | 0.60 | 0.60 |
| 417.48 | 1.82 | 1.82 |
| 433.55 | 2.29 | 2.29 |
| 482.35 | 2.27 | 2.27 |
| 498.42 | 2.74 | 2.74 |
| 421.45 | 1.65 | 1.65 |
| 437.51 | 2.12 | 2.12 |
| 471.45 | 2.53 | 2.53 |
| 486.53 | 3.60 | 3.60 |
| 403.46 | 1.51 | 1.51 |
| 428.47 | 1.38 | 1.38 |
| 444.53 | 1.85 | 1.85 |
| 443.52 | 2.39 | 2.39 |
| 437.90 | 2.16 | 2.16 |
| 437.90 | 2.16 | 2.16 |
| 453.97 | 2.63 | 2.63 |
| 453.97 | 2.63 | 2.63 |